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Ahmad, Aktsar Roskiana
Fakultas Farmasi Universitas Muslim Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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RIMPANG KECOMBRANG (Etlingera elator Jack.) SEBAGAI SUMBER FENOLIK Syarif, Rezki Amriati; Sari, Firdha; Ahmad, Aktsar Roskiana
Jurnal Fitofarmaka Indonesia Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : FAKULTAS FARMASI UNIVERSITAS MUSLIM INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (30.735 KB)

Abstract

Kecombrang (Etlingera elatior Jack.) is one of the plants growing in the area of Palopo, South Sulawesi. Kecombrang included in the Zingiberaceae family and rhizome of kecombrang widely used by the community as an antioxidant. This research aimed to determine the phenolic content on the methanol extract of the rhizome kecombrang. Methanol extract of rhizhome kecombrang obtained by maceration method with methanol P. Chemical component analysis used thin layer chromatography (TLC) is characterized by the appearance of spot. Determination of the phenolic content of the methanol extract of rhizomes kecombrang used the TLC-densitometry. The results showed that the phytochemical assay on methanol extract of kecombrang rhizomes positively countains 144.43 µg phenolic compounds.
MENCIPTAKAN DESA MANDIRI KESEHATAN DI DESA SALUKANAN KECAMATAN BARAKA KABUPATEN ENREKANG Ahmad, Aktsar Roskiana
Jurnal BALIRESO Vol 1, No 1 (2016)
Publisher : Jurnal BALIRESO

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Abstract

Kegiatan KKN-PPM dilaksanakan di Desa Salukanan Kecamatan Baraka Kabupaten Enrekang, Provinsi Sulawesi Selatan. Merupakan dataran tinggi dan desa unggulan agribisnis di Kabupaten Enrekang dengan hasil alam yang melimpah dan tanaman endemik berupa beras ketan pulu mandoti. Kelompok sasaran pada kegiatan ini adalah anak usia sekoah, remaja putri, ibu-ibu rumah tangga, ibu-ibu PKK dan karang taruna pada tiga dusun (Matarin, Gandeng, dan Tantido).Dari hasil diskusi dengan Pemerintah Desa dan tokoh-tokoh masyarakat ditemukan beberapa permasalahan masyarakat, sehingga ditawarkan beberapa kegiatan seperti :Penyuluhan kesehatan pada anak usia sekolah dan masyarakat umum. Pelatihan aplikasi tanaman obat (pengobatan herbal) dan pemanfaatan lahan untuk budidaya tanaman obat (pengelolaan TOGA). Pembuatan produk kesehatan sereal berbahan dasar pulu mandoti (beras ketan merah) untuk memberikan tambahan nilai ekonomis untuk masyarakat setempat. Menumbuhkan jiwa enterpreneurship masyarakat dengan mendorong terbentuknya kelompok-kelompok usaha pengolahan sumber daya alam sehingga masyarakat tidak hanya menjual hasil alam dalam bentuk bahan baku (bahan mentah) akan tetapi dapat menghasilkan produk produk yang bernilai ekonimis tinggi.Untuk mencapai target kegiatan KKN-PPM maka akan dilaksanakan beberapa kegiatan dengan tahapan sebagai berikut : sosialisasi kegiatan KKN-PPM, penyusunan program kegiatan (program pokok dan program tambahan), seminar awal untuk sosialisasi kegiatan, pelaksanaaan kegiatan dengan metode ceramah, diskusi, pelatihan dan praktek, seminar evaluasi, penyusunan laporan kegiatan, seminar akhir pada pekan terakhir kegiatan.
Kadar Fenolik Dan Flavonoid Total Dalam Ekstrak Metanol Daun Cemba (Acacia rugata (Lam.) Fawc. Rendle) Dahlia, Andi Amaliah; Amima, Nur Qadri; S, Aulya Rachma Arum; Syarif, Rezki Amriati; Ahmad, Aktsar Roskiana
Jurnal Fitofarmaka Indonesia Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Jurnal Fitofarmaka Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i1.786

Abstract

This study aims to determine and compare the phenolic and flavonoid content of methanol extract in Acacia rugata (Lam.) Fawc. Rendle leaves using UV-Vis spechtrophotometry and TLC-densitometry. The Acacia rugata (Lam.) Fawc. Rendle extracted by using maceration applied sonicator. The quantitative assay measured by spectrophotometer UV-Vis at wavelength 430 nm. The TLC–densitometry performed at wavelength of 254 nm and quercetin was as a standard. The results showed that the phenolic total showed 0.506 gGAE/g extract for spectrophotometer Uv-Vis and 0.879 gGAE/g extract for TLC-Densitometric. The flavonoid content reported 0.44 gQE/g extract and 0.73 gQE/mg extract for spectrophotometer UV-Vis and TLC Densitometric methods, respectively. 
SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOLIK BUAH BUNI (Antidesma bunius (L.) SPRENG) Arif Rahman; Abd Malik; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1004.954 KB) | DOI: 10.33096/jffi.v3i2.497

Abstract

Free radicals play a role in the occurrence of various degenerative diseases that require free-radical scavengers or antioxidants. Buni fruit (Antidesma bunius (L.) Spreng) has the bioactive components are Anthocyanins (flavonoids) that serves to the free radicals. This study aimed to measure the antioxidant activity of theethanol extract contained 70% fruit Buni obtained by using the method of nitric oxide. Simplicia buni macerated dried fruit with 70% ethanol. Extracts were obtained in the test antioxidant activity against nitric oxide radicals. The antioxidant activity against free radical absorbance measured by means of UV-Vis spectrophotometry at a wavelength of 546 nm and calcul ated IC50 values. The results shows that the fruit buni has potential as a free radical with IC50 value of 2.28 µg/mL and a comparison of quercetin with IC50 value of 5.88 µg/mL.
STANDARISASI EKSTRAK AIR DAUN JATI BELANDA DAN TEH HIJAU Ahmad Najib; Abd. Malik; Aktsar Roskiana Ahmad; Virsa Handayani; Rezki Amriati Syarif; Risda Waris
Jurnal Fitofarmaka Indonesia Vol 4, No 2 (2017): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (891.618 KB) | DOI: 10.33096/jffi.v4i2.268

Abstract

Teh hijau memiliki nama spesies Camellia sinensis (L.) Kuntze, family Theaceae dan Jati belanda (Guazuma ulmifolia Lam.) termasuk kedalam family sterculiaceae Tujuan Penelitian ini adalah melakukan standarisasi ekstrak air daun jati belanda dan ekstrak air the hijau. Ekstrak distandardisasi dengan beberapa dua parameter yaitu parameter spesifik dan parameter non spesifik. Kadar sari larut air pada jati belanda 12,88 % dan teh hijau 40,88, sedangkan kadar sari larut etanol pada jati belanda 4, 23 % dan pada teh hijau 4,23 %. Hasil pengujian kandungan kimia menunjukkan pada ekstrak jati belanda mengandung saponin dan flavonoid sedangkan pada teh hijau mengandung tanin dan flavonoid. Kadar air ekstrak daun jati belanda 0,95 % dan teh hijau 2,79%. Hasil kadar abu total jati belanda sebesar 37,61% dan teh hijau 36,84%. Kadar abu tidak larut asam yaitu pada jati belanda sebesar 3,54% dan teh hijau 3,77%. Hasil dari penetapan susut pengeringan pada ekstrak jati belanda yaitu 0,46 % dan teh hijau 0,46 %. Ekstrak jati belanda maupun teh hijau berdasarkan pengujian standarisasi meliputi parameter spesifik dan non-spesifik memenuhi standarisasi mutu bahan baku.
UJI TOKSISITAS EKSTRAK DAUN PLETEKAN (Ruellia tuberosa L.) DENGAN MENGGUNAKAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Nurhawa Vitalia; Ahmad Najib; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 3, No 1 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1242.626 KB) | DOI: 10.33096/jffi.v3i1.171

Abstract

Minnie root (Ruellia tuberosa L.) belongs to Acanthaceae family. In traditional medicine has been used as diuretic, antidiabetic, antipyretic and antihypertensive and it also recently been incorporated as a component in a herbal tea in Taiwan. This research is aim to determine LC50 value of Minnie root leaves extract (Ruellia tuberosa L.) to Artemia salina Leach shrimp larvae. Dryed samples extracted by graduate maceration with n-hexan, ethyl acetate and ethanol respectively. Rendamen n-hexane extract obtained as much as 1.158%, ethyl acetate extract as much as 2.017% and ethanol extract as much as 3.669 %. Based on qualitative screening used TLC method, ethyl acetate extracts and ethanol extracts of Minnie root (Ruellia tuberosa L.) leaves contain alkaloid, saponin, flavonoid and phenolic compounds. Toxicity assay Artemia salina Leach shrimp larvae have been conducted on leaves extracts of Minnie root (Ruellia tuberosa L.). Toxicity assay on sample extract of Minnie root (Ruellia tuberosa L.) leaves determine by counting the number died of larvae after 24 hours treatment. LC50 on sample calculated by probit analysis method. The toxicity assay showed LC50 of ethyl acetate extracts and ethanol extracts are toxic with LC50 266.07 ± 0.93 µg/mL and 142.160 ± 1.30 µg/mL.
RIMPANG KECOMBRANG (Etlingera elator Jack.) SEBAGAI SUMBER FENOLIK Rezki Amriati Syarif; Firdha Sari; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 2, No 2 (2015): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (316.059 KB) | DOI: 10.33096/jffi.v2i2.178

Abstract

Kecombrang (Etlingera elatior Jack.) is one of the plants growing in the area of Palopo, South Sulawesi. Kecombrang included in the Zingiberaceae family and rhizome of kecombrang widely used by the community as an antioxidant. This research aimed to determine the phenolic content on the methanol extract of the rhizome kecombrang. Methanol extract of rhizhome kecombrang obtained by maceration method with methanol P. Chemical component analysis used thin layer chromatography (TLC) is characterized by the appearance of spot. Determination of the phenolic content of the methanol extract of rhizomes kecombrang used the TLC-densitometry. The results showed that the phytochemical assay on methanol extract of kecombrang rhizomes positively countains 144.43 µg phenolic compounds.
UJI TOKSISITAS EKSTRAK ETANOL TERPURIFIKASI BIJI MAHONI (Switenia mahagoni) Virsa Handayani; Ahmad Najib; Rezki Amriati Syarif; Abdullah Mahmud; La Hamidu; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 6, No 2 (2019): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (613.207 KB) | DOI: 10.33096/jffi.v6i2.511

Abstract

Mahoni is a medical plant which have the potential as drug. The aims of this research were to analysis phytochemical content and to test the toxicity of ethanol extract of seed from Mahoni. The Phytochemicals that analyzed were total phenolic, total flavonoid and condensed tannin. Toxicity test was assessed using BSLT method. Extraction was done by maseration method using ethanol as the solvent. In BSLT method, the shrimp larvae were placed in a series of test solution of varied concentration. The value of LC50 were obtained based on calculation of shrimp larvae lethality percentage using probit analysis. LC50 values of ethanol extract were 0,95 ppm.
IDENTIFIKASI GOLONGAN SENYAWA ANTIOKSIDAN DENGAN MENGGUNAKAN METODE PEREDAMAN RADIKAL DPPH EKSTRAK ETANOL DAUN Cordia myxa L. Rezki Amriati Syarif; Muhajir Muhajir; Aktsar Roskiana Ahmad; Abd. Malik
Jurnal Fitofarmaka Indonesia Vol 2, No 1 (2015): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (606.66 KB) | DOI: 10.33096/jffi.v2i1.184

Abstract

Cordia myxa L .leaf is a plant from Boraginaceae family which is traditionally used as medicine of several skin diseases . The purpose of thid research is to know the chemical compound antioxidant activity of ethanolic extract of Cordia myxa L. leaf. The used extraction method was maceration method using 70% as solvent. Identification of coumpound group used  color reaction and  precipitation method respectively. While antioxidant activity test used free radical scavenging method of DPPH (1,1-dyphenyl-2 pycril Hydrazil). From the extraction result, that was found that %redamen of ethanolic extract of  Cordia myxa L .leaf 2.76%. While the determination of chemical compound showed that ethanolic extcract of  Cordia myxa L .leaf containing steroid, flavonoid, saponin, and phenol. The result antioxidant activity assay showed that ethanolic extract of Cordia myxa L .leaf has intermediate free antiradical activity with IC50 value 54.92 µg/mL. But it is potensial is lower than Quarcetin which has IC50 value 0.52 µg/mL.
UJI ANTIMITOSIS EKSTRAK ETANOLIK KLIKA SIRSAK (Annona muricata L.) TERHADAP SEL TELUR LANDAK LAUT (Tripneustes gratilla L.) TERFERTILISASI Niken Pratiwi Liambo; Abd. Malik; Aktsar Roskiana Ahmad
Jurnal Fitofarmaka Indonesia Vol 3, No 2 (2016): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (934 KB) | DOI: 10.33096/jffi.v3i2.218

Abstract

Soursop belongs to Annonaceae family. In the traditional medicine has been as anticancer, antivirus, wound healing, lowering uric acid levels. This study aims to determine the IC80value extract ethanolic of soursop bark to sea urchin egg (Tripneustes gratilla L.) fertilized. Dryed sample extracted by maceration method using ethanol solvent. Retrieved rendamen extract as much as 2,525 %. Based on qualitative test chemical components that extract ethanolic of soursop bark contain   tannins, saponins, alkaloids and flavonoids. Antimitotic test conducted on extract ethanolic of soursop bark (A.muricata) obtained by looking at the sea urchin egg cell inhibition (Tripneustes gratilla L.) to calculate IC80 values by probit analysis method. Antimitotic test results showed that the extract ethanolic of soursop bark (A.muricata) as an antimitotic active with IC80 values of 1,56 x 10-3 mg/ml. Although the potential is lower than that of vincristine inhibit 80 % of eggs fertilized with Tripneustes gratilla L. IC80value is 7,046 x 10-7 mg/ml.
Co-Authors A Amaliah Dahlia ABD. MALIK Abd. Malik Abdul Malik Abdul Rasyid, Faradiba Abdullah Mahmud Ahmad Najib Amima, Nur Qadri Anak Agung Istri Sri Wiadnyani Andi Afifah Amdar Anisa, Rianti Arif Rahman Asni Amin Asriani Suhaenah Aulya Rachma Arum Bahria Bahria Bayu Putra, Bayu Dwiyanti Puspitasari Fadlina Chany Saputri Fadliyah, Nurfadhilah Firdha Sari Firdha Sari, Firdha Hamidu, La Harti Widiastuti Harti Widiastuti Hasnaeni hasnaeni, Hasnaeni Hidayah, Andi Nurul Annisa HM, Nur Rahmah I Ketut Suada Juwita Juwita Juwita Juwita, Juwita Miswati Sudir Miswati Sudir Miswati Sudir, Miswati Muhajir Muhajir Murfat, Zulkifli Niken Pratiwi Liambo Niza, Nabila Ikhwanun Nur Qadri Amima Nur Rezky Khairun Nisaa Nurhawa Vitalia Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif Rezki Amriati Syarif, Rezki Amriati Risda Waris Rizki Yulianti R Rizqi Nur Azizah S, Aulya Rachma Arum Saida I. Suradji Selpida Handayani Siti Afrianty Daniya Ratulangi Siti Afrianty Daniya Ratulangi, Siti Afrianty Daniya Tiara Katulista Islamia Tulnisa, Hijeria Umi K. R. Karim Virsa Handayani Wahyu Wira Utami