Uji Aktivitas Ekstrak Etanol Daun Labu Siam (Sechium edule Jacq. Swartz) sebagai Antibakteri Mycobakterium smegmatis

Christel Sambou (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Douglas N. Pareta (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Sarah Sambow (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Wilmar Maarisit (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Jabes Kanter (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Jeane Mongi (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Hanna M. Rumagit (Program Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Selvana Tulandi (Program Studi Biologi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Joke L. Tombuku (Program Studi Biologi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Reky R. Palandi (Program Studi Biologi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)
Nerni O. Potalangi (Program Studi Biologi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon, Tomohon, Indonesia.)

Journal of Pharmaceutical and Sciences.
JPS Volume 6 Nomor 3 (2023)

The membrane structure of Mycobacterium smegmatis is similar to that of Mycobacterium tuberculosis, allowing TB testing to be performed on Mycobacterium smegmatis without directly testing on Mycobacterium tuberculosis. Antibacterial testing uses the paper disc method with several treatments, namely extract concentrations of 1 µg/disc, 2 µg/disc, and 4 µg/disc, as well as positive control streptomycin 2 µg/disc and negative control 70% ethanol. The research results obtained at Extract Concentrations of 1, 2, and 4 µg/disc have moderate antibacterial activity seen from the inhibitory zone diameter, namely 8.73 mm, 9.17 mm, and 9.73 mm, and the positive control is strong because it has a zone diameter of 13.27 and the negative control does not give a zone. The conclusion is that the extract of siam pumpkin leaves has moderate antibacterial activity.