Molekul: Jurnal Ilmiah Kimia
Vol 17 No 2 (2022)

Synthesis and Antimicrobial Activity of Silver N-Methyl Chitosan

Kurniasih, Mardiyah (Unknown)
Purwati, Purwati (Unknown)
Dewi, Ratna Stia (Unknown)
Budiarni, Kasandra (Unknown)



Article Info

Publish Date
21 Jul 2022

Abstract

This study synthesized silver N-methyl chitosan (Ag-NMC) and tested it for its antimicrobial and antifungal activity. Ag-NMC was characterized by FTIR, XRD, measured for its molecular weight (MW), solubility, and toxicity. The antimicrobial activity was tested by the agar diffusion method, determining the MIC (Minimum Inhibitory Concentration), MBC (Minimum Bactericidal Concentration) against Staphylococcus aureus and Escherichia coli bacteria, and determining the Minimum Fungicidal Concentration (MFC) against the fungus Candida albicans. The results showed that Ag-NMC had MW, solubility , and LC50 of 555.65 g/mol, 50 mg/mL, 945,492 mg/L, respectively. The diameter of the inhibition zone from the resulting https://www.surreyhillschallenge.com/ diffusion test showed that Ag-NMC had better antimicrobial activity than N-methyl chitosan (NMC) and chitosan. The MIC, MBC, and MFC values of Ag-NMC were always lower than that of NMC and chitosan.

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Journal Info

Abbrev

jm

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology

Description

The MOLEKUL is dedicated to fostering advancements in all branches of chemistry and its diverse sub-disciplines. It aims to publish high-quality research encompassing a wide range of topics, including but not limited to Pharmaceutical Chemistry, Biological Activities of Synthetic Drugs, ...