This research aimed to develop CPS learning media based on the Intelligent Tutoring System to improve the HOTS abilities of Science Education Students, especially on the Colligative Properties of Solutions material. The method used in this research was research and development with 4D method, namely define, design, develop and disseminate. In the definition stage, learning objectives were formulated. The design stage was carried out by designing learning media, while at the development stage, learning media were validated by media experts and material experts, the dissemination stage was carried out via YouTube and Unib e-learning. The results of the research show that the learning media validation scores by material experts and media experts were at 73 and 55 in the "Very Appropriate" category, respectively. The results of students' assessment of the feasibility of learning media were in the "Very feasible" category with conversion score of 34.94. Student responses to CPS learning media showed a mean score of 252.8 with conversion value of 4.23 in the "strongly agree" category. Student HOTS in this study was measured using pretest and posttest questions which had been prepared using HOTS indicator. Based on the evaluation results, it is known that the average student pretest score was 53.38 and the student posttest was 81.98. Meanwhile, the N-Gain value is 0.61 in the "Medium" category. Based on the research results, it can be concluded that the CPS learning media developed was very suitable for use in supporting the learning process and can increase the HOTS of science education students.
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