The International Science of Health Journal
Vol. 1 No. 4 (2023): December : The International Science of Health Journal

Literature Review Role Of Matrix Metalloproteinase In Cancer Pain

Ekawaty Suryani Mastari (Unknown)
Fitri Aidani Ulfa (Unknown)
Ningrum Wahyuni (Unknown)
Noradina Noradina (Unknown)
Meriani HS (Unknown)

Article Info

Publish Date
30 Dec 2023

Abstract

Cancer pain occurs in more than half of cancer patients and affects their quality of life. The complexities of proinflammatory molecules in the tumor microenvironment contribute to pain. The MMPs, as proteolytic enzymes involved in cancer cell migration towards the surrounding environment, demonstrate their connection to the development of pain in cancer. As complex molecules, MMPs can be influenced by various cytokines and chemokines, mainly throughout neuroinflammation, which decreases neuron sensitivity and boosts hyperexcitability in pain-controlling mechanisms.

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Journal Info
The International Science of Health Journal
Website

Abbrev

ishel

Publisher

Sekolah Tinggi Ilmu Kesehatan Kesdam IV, Diponegoro

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Description

Praktek Ilmu Bedah, Farmasi, Persalinan, Kesehatan Anak, Kesehatan Jiwa, Kesehatan Masyarakat, Kedokteran Gigi, Ilmu Pendidikan Kesehatan, Kebidanan, Ilmu Kesehatan dan Keperawatan, Kebijakan dan Manajemen Kesehatan, Gizi Masyarakat, Kesehatan Lingkungan, Epidemiologi, Kesehatan Reproduksi, Promosi ...