Indonesian Journal of Science and Pharmacy
Vol. 2 No. 1 (2024): Indonesian Journal of Science and Pharmacy

Toxicity Test Of Ethanol Extract Of Pletekan Leaves (Ruellia tuberosa L) Using The Brine Shrimp Lethality Test (BSLT) Method

Fajri, Fajrilda Aqilah (Unknown)
ridwanto, ridwanto (Unknown)
Pulungan, Ainil Fithri (Unknown)
Rani, Zulmai (Unknown)



Article Info

Publish Date
30 Aug 2024

Abstract

The pletekan plant (Ruellia tuberosa L.) is a family of Acanthaceae Ruellia tuberosa L.) one of the plants used as a medicinal plant, especially the leaves, have been used empirically for therapy as a diuretic, antidiabetic, antihypertensive. Also used in the treatment of syphilis, kidney stones, cancer, heart disease, colds, hypertension and digestive problems. The purpose of this study was to determine the toxicity by determining the LC50 in the ethanol extract of pletekan leaves (Ruellia tuberosa L). The analysis carried out was a toxicity test on the ethanol extract of pletekan leaves against Artemia Salina Leach shrimp larvae using the BSLT method with various concentrations, namely 10, 15, 20, 25, 30, 35, and 40 ppm and determining the LC50 value with probit analysis. Based on the results of the toxicity test, the LC50 value was 96.4595 µg/Ml. These results show that the ethanol extract of pletekan leaves (Ruellia tuberosa L) has a toxic effect on Artemia Salina Leach shrimp larvae.

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Journal Info

Abbrev

IJSP

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

Indonesian Journal of Science and Pharmacy (IJSP) accepts scientific articles as original research articles, short communication, reviews, and mini-reviews from anyone without any discrimination, as long as they submit articles that meet scientific principles. Indonesian Journal of Science and ...