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All Journal Indonesian Journal of Science and Pharmacy
Fajri, Fajrilda Aqilah
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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Toxicity Test Of Ethanol Extract Of Pletekan Leaves (Ruellia tuberosa L) Using The Brine Shrimp Lethality Test (BSLT) Method Fajri, Fajrilda Aqilah; ridwanto, ridwanto; Pulungan, Ainil Fithri; Rani, Zulmai
Indonesian Journal of Science and Pharmacy Vol. 2 No. 1 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v2i1.71

Abstract

The pletekan plant (Ruellia tuberosa L.) is a family of Acanthaceae Ruellia tuberosa L.) one of the plants used as a medicinal plant, especially the leaves, have been used empirically for therapy as a diuretic, antidiabetic, antihypertensive. Also used in the treatment of syphilis, kidney stones, cancer, heart disease, colds, hypertension and digestive problems. The purpose of this study was to determine the toxicity by determining the LC50 in the ethanol extract of pletekan leaves (Ruellia tuberosa L). The analysis carried out was a toxicity test on the ethanol extract of pletekan leaves against Artemia Salina Leach shrimp larvae using the BSLT method with various concentrations, namely 10, 15, 20, 25, 30, 35, and 40 ppm and determining the LC50 value with probit analysis. Based on the results of the toxicity test, the LC50 value was 96.4595 µg/Ml. These results show that the ethanol extract of pletekan leaves (Ruellia tuberosa L) has a toxic effect on Artemia Salina Leach shrimp larvae.
Co-Authors Fithri Pulungan, Ainil Ridwanto Ridwanto Zulmai Rani