Jurnal Biologi Tropis
Vol. 25 No. 2 (2025): April-Juni

Blood Glucose Level of Hyperglycemia Rats (Rattus novergicus) after Neem Gum (Azadirachta indica) Administration

Utami, Eva Tyas (Unknown)
Fajariyah, Susantin (Unknown)
Lelono, Asmoro (Unknown)
Nihayah, Husnatun (Unknown)



Article Info

Publish Date
30 Apr 2025

Abstract

Neem, a member of the Meliaceae family, is recognized to have the ability to decrease blood glucose levels. The study’s goal is to determine the neem gum (NG) impact in overcoming hyperglycemia in Wistar rats. There were three groups of rats in this study: (1) control, (2) hyperglycemic group (which got Streptozotocin (STZ) treatment but not NG treatment), and (3) hyperglycemic group (which got STZ treatment and 15% NG treatment) for three weeks. The T test results revealed notable variations before and after giving STZ. The finding indicated the blood glucose level before STZ induction in control was 86.50 ± 3.15 mg/dL, and the diabetic rat group (treated with STZ) was 87.60 ± 4.56 mg/dL. After STZ induction (7th day), there was a noteworthy rise in amount of glucose, namely 435.34 ± 120.33 mg/dL compare to the STZ treatment. The Duncan Multiple Range (DMRT) test showed there is no discernible difference between the STZ and NG treatments; however, there was a downward trend on days 14, 21, and 28. The conclusion of this study is that 15% NG has failed to decreas ehyperglycemia to normal blood glucose levels.

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Journal Info

Abbrev

JBT

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

Description

Jurnal Biologi Tropis (ISSN Cetak 1411-9587 dan ISSN Online 2549-7863) diterbitkan mulai tahun 2000 dengan frekuensi 2 kali setahun oleh Program Studi Pendidikan Biologi PMIPA FKIP Universitas Mataram, berisi hasil penelitian dan ulasan Ilmiah dalam bidang Biologi ...