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Prevalensi Buta Warna pada Siswa Sekolah Dasar di Pulau Gili Ketapang Kabupaten Probolinggo Nailatur Rifdah; Rike Oktarianti; Hidayat Teguh Wiyono; Asmoro Lelono; Husnatun Nihayah
Jurnal Ilmiah Biosaintropis (Bioscience -Tropic) Vol 7 No 2 (2022): Januari 2022
Publisher : Fakultas Matematika & Ilmu Pengetahuan Alam - Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (765.482 KB) | DOI: 10.33474/e-jbst.v7i2.453

Abstract

Buta warna merupakan salah satu kendala dalam proses pembelajaan setiap siswa tingkat dasar yang harus diketahui sejak dini. Buta warna utamanya disebabkan oleh faktor genetik. Buta warna merupakan kelainan genetik sex linkage pada kromosom X. Tujuan dari penelitian ini yaitu untuk mengetahui prevalensi penderita buta warna, frekuensi alel buta warna dan normal, dan mengetahui diagram silsilah keluarga penderita buta warna. Pengujian buta warna menggunakan metode Ishihara. Siswa yang diambil sebagai sampel yaitu 255 siswa yang telah dipilih secara acak, dengan rentang usia 8-12 tahun. Pengambilan sampel sesuai dengan prosedur pada Ethical clearance nomor 1224/UN25.8/KEPK/DL/2021. Hasil penelitian menunjukkan bahwa prevalensi penderita buta warna sebesar 3.14% dan prevalensi rang normal sebesar 96.86%. Frekuensi alel buta warna dan alel normal berturut-turut adalah 0,023 dan 0,977. Diagram silsilah pada keluarga penderita buta warna menunjukkan bahwa pola pewarisan buta warna adalah pola pewarisan bersilang (criss cross inheritance).
DIURETICS EFFECT OF SALAK (Salacca zalacca) SEED EXTRACT TO KIDNEY HISTOPATHOLOGICAL STRUCTURE OF THE WISTAR MALE RATS (Rattus norvegicus) Rike Oktarianti; Nur Aisyah Septiana; Asmoro Lelono
BIOEDUKASI Vol 19 No 2 (2021)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v19i2.25373

Abstract

Salak seed are used as natural diuretics, it's contain secondary metabolites i.e alkaloids, flavonoids and tannins. Diuretics are compounds that can increase the rate of excretion of urine volume and increase the excretion of mineral salts in the urine. The study was to determine the diuretic effect of salak seed extract on the histopathological structure of the kidney. Salak seed extract was made by maceration method using 70% ethanol and then evaporated. Rats were divided into 4 treatment groups, negative control and 3 treatment groups with the administration of salak seed extract for 7 days orally at a dose of 0.28g/kg body weight, 0.56g/kg body weight and 1.12g/kg body weight. The results showed that the treatment of salak seed extract orally for 7 days could increase urine volume. The treatment of dose 1.12g/kg body weight had highest diuretic effect as indicated by the volume of urine produced 5.00 ml. The treatment salak seed extract had no effect on creatinine and urea levels. The all treatment doses of salak seed extract had no effect on the kidney histopathological structure, i.e it was not effect on glomerular diameter or did not cause atrophy of kidney glomerular.
Waste Valuation and Problems Encountered In Waste Bank Management: A Case Study at BSU ASRI BMP Asmoro Lelono; Nur Asyia Alfiyani; Rini Nur Intani
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 1 No. 1 (2023): Mei
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v1i1.359

Abstract

Community participation-based waste management has been carried out by DKLH Jember Regency through the establishment of the Main Waste Bank its derivative organization, namely the Unit Waste Bank at a lower level. In this system, the effort being made is the integration of waste management, starting from the household as a producer, followed by sorting, then depositing it to BSU and ending with delivery to a temporary warehouse so that the waste is handled properly. This article aims to explore the potentials and problems encountered in the management of a Waste Bank which involves the participation of residents while still paying attention to aspects of economic feasibility. The research was carried out using the analitcal descriptive via interview and analysis of primary data owned by BSU ASRI BMP with due observance of scientific principles and maintaining the independence and interests of the authors. From the results of the research it is known that waste valuation efforts by providing economic value to each component of waste produced by each household are able to generate citizen interest in sorting and depositing the waste produced. The main contributors in the transfer of inorganic waste from BSU to BSI sequentially are paper, plastic and metal waste with the highest exchange rate ratio in metal waste. The main problem faced in the management of waste banks is the motivation of residents to independently handle daily waste. Besides that, there are also management constraints because the managers are housewives who must divide their time and attention for routine daily activities.
Application of fish hydrolyzate to reduce feed requirements and improve the health of broiler chickens Lelono, Asmoro; Sjaifullah, Achmad
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 1 No. 2 (2023): November
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v1i2.471

Abstract

Feed management, which accounts for 70% of overall production expenses, is one of the cornerstones of effective broiler chicken farming. The body weight, health, and nitrogen levels in faeces can all be improved by adding additives to feed. This community service's goal is to guide and support broiler chicken breeders in their usage of fish hydrolyzed for feed management. This activity was carried out in August and September 2023 in the chicken farming partner owned by Mrs. Cholili's with a production capacity of up to 20,000 in Mumbulsari village, Mumbulsari district, Jember Regency. The methods are counselling, feeding practices and assistance during the production phase. The outcome is mastering the technique for adding fish hydrolyzed to enhance the health and growth performance of chickens. This skill and knowledge could be implemented by other farmers to maximize yields by using fish hydrolyzate.
Prevalence of Phenylthiocarbamide (PTC) Taste Sensitivity and Colour Blindness in Tengger Tribe Population, Ranupani Village, Senduro, Lumajang Oktarianti, Rike; Putra, Iguh Widigda; Arofa, Resmining Mega; Lelono, Asmoro
BERKALA SAINSTEK Vol 9 No 4 (2021)
Publisher : Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bst.v9i4.26435

Abstract

The taste of sensitivity of phenylthiocarbamide (PTC), is autosomal dominant trait inherited while the colour blindness is a sex linked genetic trait on the X chromosome. The purpose of this study was to determine the distribution of taster and non taster phenotypes, prevalence of color blindness, frequency of taster and non taster alleles, and frequency of color blind alleles, as well as pedigree analysis in non taster and color blind families. The research was conducted on the Tengger tribe, in Ranupani village, Senduro, Lumajang. Determination of the sample is carryout randomly. Detection of the ability to taste PTC was respondents to taste the PTC solution from the lowest concentration of 0.32mg/L (P13) to the highest concentration of 1300 mg/L (P1). Color blindness detection by the Ishihara method. The results of the study showed that the distribution of the taster was 98.1% while the non-taster was 1.9%. The allele frequency of the dominant taster (T) was 0.86 and the recessive allele non taster (t) is 0.14. The prevalence of color blindness in the population of the Tengger tribe was 0.63% and the allele frequency for color blindness was 0.013. The pedigree analysis of non taster family showed that non taster individuals were born from taster couple (Tt) or from couple of non taster (tt) with tasters (Tt) heterozigot. While the pattern of inheritance of color blindness was criss-cross inheritance pattern, which is passed from mother to son.
The Application of Composter Reactor Technology Using The Anaerobic Fermentation Method for Processing Organic Waste at a Residential Scale Lelono, Asmoro; Alfiyani, Nur Asyia; Intani, Rini Nur; Dewi, Rosita Fitrah; Sari , Dwi Rihma
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 2 No. 2 (2024): November
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v2i2.1516

Abstract

Community-based waste management is a program designed to empower citizens, who are the primary producers of household waste, to take responsibility for ensuring that the waste they generate is sorted and utilized as efficiently as possible before disposal. This initiative aims to empower residents to manage organic waste by applying composter reactor technology through anaerobic fermentation methods within residential areas. To implement this program, we have partnered with the BSU ASRI BMP Waste Bank Unit, which has been active since 2021 and possesses experience and expertise in waste management. The activity began with planning, followed by a series of steps including socialization, demonstrations, the creation, and distribution of composters. The program concluded with an evaluation to assess the sustainability and effectiveness of the activities carried out. The results show that the application of composter reactor technology on the dasa wisma community has successfully transformed household waste into compost and liquid organic fertilizer. These products have been used as planting media and fertilizers for ornamental and horticultural plants at home gardens. Additionally, the use of decomposers has significantly reduced the volume of organic waste previously discarded by converting it into valuable products.
Struktur Histologi Trabekula Femur Mencit (Mus musculus L) Orkidektomi Pasca Pemberian Ekstrak tempe Kedelai Fajariyah, Susantin; Muta’alimah, Siti Nafi’atul; Utami, Eva Tyas; Lelono, Asmoro; Nihayah, Husnatun
JURNAL BIOS LOGOS Vol. 14 No. 3 (2024): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v14i3.56668

Abstract

Testosterone deficiency is caused by, among other things, old age, chronic disease, and testicular cancer, which results in decreased bone density. Estrogen plays a more important role in the process of bone growth and resorption than the hormone testosterone. Therefore, to prevent a decrease in density in conditions of testosterone deficiency, it is necessary to administer external phytoestrogens, including tempeh, containing isoflavones deidzein dan genistein. The aim of this study was to determine the effect of administering tempeh extract on the histological structure of the femoral trabeculae of orchidectomized mice. Mice were divided into 4 groups, namely negative control (without orchidectomy), positive control (orchidectomy), and 2 orchidectomy treatment groups, followed by administration of tempe extract at a dose of 0.6 g/ml/day (D1) and 1.2 g/ml/day (D2). Tempeh extract was administered by gavage for 15 days after a 30-day healing period for bilateral orchidectomy. One day after the last administration of tempeh extract, the mice were anesthetized and dissected to remove the femur bones to make preparations using the paraffin method and HE staining. The parameters observed were the number of osteoblasts and osteoclasts and the thickness of the femoral trabeculae. Giving soybean tempeh extract at a dose of 0.6 mg/ml/day by gavage for 15 days can cause an increase in the number of osteoblasts and trabecular thickness, as well as reducing the number of osteoclasts in the femur of orchidectomized mice.
Blood Glucose Level of Hyperglycemia Rats (Rattus novergicus) after Neem Gum (Azadirachta indica) Administration Utami, Eva Tyas; Fajariyah, Susantin; Lelono, Asmoro; Nihayah, Husnatun
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8748

Abstract

Neem, a member of the Meliaceae family, is recognized to have the ability to decrease blood glucose levels. The study’s goal is to determine the neem gum (NG) impact in overcoming hyperglycemia in Wistar rats. There were three groups of rats in this study: (1) control, (2) hyperglycemic group (which got Streptozotocin (STZ) treatment but not NG treatment), and (3) hyperglycemic group (which got STZ treatment and 15% NG treatment) for three weeks. The T test results revealed notable variations before and after giving STZ. The finding indicated the blood glucose level before STZ induction in control was 86.50 ± 3.15 mg/dL, and the diabetic rat group (treated with STZ) was 87.60 ± 4.56 mg/dL. After STZ induction (7th day), there was a noteworthy rise in amount of glucose, namely 435.34 ± 120.33 mg/dL compare to the STZ treatment. The Duncan Multiple Range (DMRT) test showed there is no discernible difference between the STZ and NG treatments; however, there was a downward trend on days 14, 21, and 28. The conclusion of this study is that 15% NG has failed to decreas ehyperglycemia to normal blood glucose levels.
IN-SILICO ANALYSIS OF THE INTERACTION BETWEEN D7 PROTEIN FROM THE SALIVARY GLAND OF Ae. albopictus AND Thromboxane A2 FOR DEVELOPING ANTIPLATELET AGENT Wathon, Syubbanul; Senjarini, Kartika; Oktarianti, Rike; Lelono, Asmoro
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 12 No. 1 (2025)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2025.8176

Abstract

The salivary glands of mosquito vector diseases contain various biological components which facilitate blood-feeding into the host's body. These components are mostly protein molecules. Numerous protein molecules in the salivary glands have gained substantial research emphasis to determine their role and function, including those in the salivary glands of Ae. albopictus. D7 protein is the main component in Aedes salivary glands, which aids in inhibiting platelet aggregation by binding to the Thromboxane A2 (TxA2) during the blood-feeding. TxA2 is a eicosanoid molecule that stimulates platelet aggregation. The protein's ability to bind TxA2 shows that this protein has potential as a new antiplatelet agent. The examination of the D7 protein in binding TxA2 was performed through an in-silico approach using the molecular docking method. This research included selecting the 3D model of the D7 protein and the TxA2 ligand, preparing the 3D model of the D7 protein, native ligands, and test ligands, targeted molecular docking method, validating the molecular docking, analysis and visualization of the docking results. The molecular docking validation shows an RMSD value of 1.657 Å. The results of molecular docking show an ΔG value of -5.60 kcal/mol, meaning that the D7 protein can bind to the TxA2 ligand stably and spontaneously. The active site of the D7 protein in binding the TxA2 ligand consists of several amino acid residues, namely THR 190, GLU 268, TYR 178, PHE 154, ILE 175, ARG176, VAL 293, TYR 248, and TYR 178. The ability of D7 protein to bind TxA2 as an inducer of platelet aggregation has demonstrated its potential as a novel antiplatelet agent. These results can pave further development of drug discovery in the medical and pharmaceutical fields.
Assessing The Javan Leopard Presence and Prey Abundance: Insights from Camera Trap Surveys in Meru Betiri National Park East Java Indonesia Kholiq, Nur; Sulistyowati, Hari; Tabah Wibisono, Hariyo; Asmoro Lelono; Retno Wimbaningrum; Sattya Arimurti; Arif Mohammad Siddiq; Adi Sucipto
BIOEDUKASI: Jurnal Biologi dan Pembelajarannya Vol. 23 No. 2 (2025)
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI FAKULTAS KEGURUAN DAN ILMU PENDIDIKAN UNIVERSITAS JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bioedu.v23i2.53715

Abstract

The use of incomplete or imbalanced data in ecological modelling and conservation planning can lead to inaccurate predictions due to limitations in detection methods. Therefore, obtaining comprehensive and precise empirical data on species presence and availability, particularly prey species is essential. This study aims to: (1) identify the presence of Javan leopards and their potential prey species, and (2) estimate the relative abundance indices (RAI) of each prey species. Using camera trap data from the Meru Betiri National Park (MBNP) survey conducted in 2024, we recorded 24 species, including the Javan leopard, and identified seventh potential prey species. We estimated relative abundance of each potential prey species was determined by dividing the number of individuals recorded in independent photos or videos by the total number of trap days and multiplied by 100. The result of RAI analysis indicated that the most abundant prey species in the study area was the long-tailed macaque, with an RAI value of 44.16 individuals per 100 trap-days, banteng was the least frequently detected species, appearing in only three independent images, with an RAI value of 0.23. The presence of Javan leopards, a charismatic flagship species, highlights the ecological significance of this area and provides valuable data for biodiversity management, serving as a foundation for future research and conservation efforts.