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The Effect of Ethanol Extract Turmeric Rhizome (Curcuma Longa) to Histologycal Structure of Rat Rectum Induced Dextran Sodium Sulphate (DSS) Nikmah, Lidia Maziyyatun; Fajariyah, Susantin; Mahriani, M.
Jurnal ILMU DASAR Vol 20 No 1 (2019)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (108.158 KB) | DOI: 10.19184/jid.v20i1.7629

Abstract

Turmeric (Curcuma longa) is a plant that people use as a traditional medicine to treat some diseases such as: anti-inflammatory, antidiarrhea, antioxidants, hepatoprotector, and others. One of the main chemical compounds contained in turmeric and has a role as anti-inflammatory is curcumin. This study was conducted to determine the effect of ethanol extract of turmeric rhizome (Curcuma longa) on the histologycal structure of rat rectum induced by Dextran Sodium Sulphate (DSS). Wistar strain rats was divided into three groups: negative control group, positive control group (1% DSS), and DSS treatment group 1% + ethanol extract of turmeric rhizome dose 200mg/KgBB. DSS is given ad libitum, while ethanol extract of turmeric rhizome is given orally. We used paraffin method and Haematoxilyn Eosin staining to make the preparation organ. The data were analyzed using One Way ANOVA test, Duncan Multiple Range Test (DMRT) test, and correlation test. The result of this study is DSS administration has an effect on decreasing average of crypt, number of Goblet cell, and depletion of rectal mucous layer. While treatment of extract turmeric rhizome can increase height of crypt and number of Goblet cell in rectal mucosal layer of rat. Keywords: Extract of turmeric rhizome, DSS, rectum, Rattus norvegicus
Keanekaragaman Jenis Echinoidea di Zona Intertidal Pantai Jeding Taman Nasional Baluran Ilman Huda, Muhammad Aris; Sudarmadji, S.; Fajariyah, Susantin
BERKALA SAINSTEK Vol 5 No 2 (2017)
Publisher : Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/bst.v5i2.5531

Abstract

Zona intertidal merupakan daerah yang terletak diantara pasang tertinggi dan surut terendah, yang mewakili peralihan dari kondisi lautan ke kondisi daratan. Luas zona intertidal sangat terbatas, akan tetapi memiliki faktor lingkungan yang sangat bervariasi, sehingga memiliki keanekaragaman organisme yang tinggi salah satunya adalah kelas Echinoidea. Kelas Echinoidea termasuk dalam anggota Filum Echinodermata yang tersebar mulai dari daerah intertidal sampai laut dalam. Echinoidea umumnya menghuni ekosistem terumbu karang dan padang lamun. Pantai Jeding merupakan pantai yang terletak di wilayah Taman Nasional Baluran yang masih belum pernah dilakukan penelitian mengenai keanekaragaman Echinoidea. Penelitian ini bertujuan untuk mengetahui keanekaragaman dan kesamarataan jenis Echinoidea di zona intertidal Pantai Jeding Taman Nasional Baluran. Metode yang digunakan dalam pengambilan sampel adalah metode transek-plot sistematis. Hasil penelitian didapatkan 8 jenis Echinoidea yang terdiri 4 ordo, 6 famili, 8 genus dan 8 spesies. Memiliki indeks Keanekaragaman (H’) jenis yang tergolong sedang dan Indeks kesamarataan (J’) Jenis yang tergolong sedang.Kata Kunci: Zona Intertidal, Echinoidea, Keanekaragaman, Pantai jeding.
Distribution Pattern of Sand Dollar (Arachnoides placenta) in the Intertidal Ecosystem of Duta Coastal, Probolinggo Regency Setiawan, Rendy; Amalia, Rizqy; Fajariyah, Susantin; Kurniawan, Joko
Buletin Oseanografi Marina Vol 13, No 3 (2024): Buletin Oseanografi Marina
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/buloma.v13i3.63314

Abstract

Species Arachnoides placenta can be found in tropical waters, one of which is in the intertidal ecosystem in Duta Coastal. Substrate types at Duta Coastal are dominated by sand and silt substrates and a small portion of muddy sand substrate. The various types of substrates at Duta Coastal are thought to be causing the population A. placenta choose a suitable habitat for their life, so that it can affect the pattern of distribution and density of A. placenta. This research aims to determine the distribution pattern and density of A. placenta in the intertidal ecosystem in Duta Coastal. This study used the method of systematic transect plots. Plots measuring 1x1 m were placed on the transects with a distance between plots of 10 meters. The number of plots laid was 332 plots. The results show the number of individuals A. placenta in the Duta Coastal intertidal ecosystem 828 individuals. The population of the A. placenta species in the Duta Coastal intertidal ecosystem is quite large because the type of substrate is suitable for the life of A. placenta Morisita Index value for the distribution pattern A. placenta is 9.3. Distribution pattern A. placenta in the Duta Beach intertidal ecosystem classified as aggregated and density values A. placenta in the intertidal ecosystem in Duta Coastal is 2.5 ind/m2. 
Struktur Histologi Trabekula Femur Mencit (Mus musculus L) Orkidektomi Pasca Pemberian Ekstrak tempe Kedelai Fajariyah, Susantin; Muta’alimah, Siti Nafi’atul; Utami, Eva Tyas; Lelono, Asmoro; Nihayah, Husnatun
JURNAL BIOS LOGOS Vol. 14 No. 3 (2024): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v14i3.56668

Abstract

Testosterone deficiency is caused by, among other things, old age, chronic disease, and testicular cancer, which results in decreased bone density. Estrogen plays a more important role in the process of bone growth and resorption than the hormone testosterone. Therefore, to prevent a decrease in density in conditions of testosterone deficiency, it is necessary to administer external phytoestrogens, including tempeh, containing isoflavones deidzein dan genistein. The aim of this study was to determine the effect of administering tempeh extract on the histological structure of the femoral trabeculae of orchidectomized mice. Mice were divided into 4 groups, namely negative control (without orchidectomy), positive control (orchidectomy), and 2 orchidectomy treatment groups, followed by administration of tempe extract at a dose of 0.6 g/ml/day (D1) and 1.2 g/ml/day (D2). Tempeh extract was administered by gavage for 15 days after a 30-day healing period for bilateral orchidectomy. One day after the last administration of tempeh extract, the mice were anesthetized and dissected to remove the femur bones to make preparations using the paraffin method and HE staining. The parameters observed were the number of osteoblasts and osteoclasts and the thickness of the femoral trabeculae. Giving soybean tempeh extract at a dose of 0.6 mg/ml/day by gavage for 15 days can cause an increase in the number of osteoblasts and trabecular thickness, as well as reducing the number of osteoclasts in the femur of orchidectomized mice.
Species Diversity of Fiddler Crabs (Uca spp.) in the Mangrove Ecosystem of Duta Coastal, Probolinggo Regency, East Java Setiawan, Rendy; Anjani, Rifkah Ajeng; Fajariyah, Susantin; Cahyono, Haris; Kurniawan, Joko
Jurnal Kelautan Tropis Vol 28, No 1 (2025): JURNAL KELAUTAN TROPIS
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkt.v28i1.24299

Abstract

Fiddler crab (Uca spp.) belongs to the Order Decapoda and Family Ocypodidae, which live by making burrows in the substrate between mangrove plants. The presence of fiddler crabs plays an important role in mangrove ecosystems, which can increase sediment mineralisation due to burrows that can increase oxygen distribution into the sediment. This research was conducted in the mangrove ecosystem of Duta coastal, Probolinggo Regency. The method used when sampling biota in this study is the transect-plot method, which is used to place 1x1 m2 plots systematically along the transect. Sampling of fiddler crabs was carried out at the lowest low tide. Samples taken were fiddler crabs in the plot. Data on the species found, the number of individuals of each species, and the total number of individuals obtained from species composition were used to calculate species diversity. Fiddler crabs (Uca spp.) found in the mangrove ecosystem Duta coastal were 10 species, namely U. perplexa, U. rosea, U. vocans, U. annulipes, U. triangularis, U. coarctata, U. tetragonon, U. vomeris, U. forcipata, and U. dussumieri. The diversity value of fiddler crab species in the Ambassador Coastal Mangrove ecosystem is moderate (Hˈ = 2.209). All species of fiddler crabs were found in the muddy sand substrate type, because the burrow structure is strong, so that when the tide, the burrow condition is maintained.
Blood Glucose Level of Hyperglycemia Rats (Rattus novergicus) after Neem Gum (Azadirachta indica) Administration Utami, Eva Tyas; Fajariyah, Susantin; Lelono, Asmoro; Nihayah, Husnatun
Jurnal Biologi Tropis Vol. 25 No. 2 (2025): April-Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i2.8748

Abstract

Neem, a member of the Meliaceae family, is recognized to have the ability to decrease blood glucose levels. The study’s goal is to determine the neem gum (NG) impact in overcoming hyperglycemia in Wistar rats. There were three groups of rats in this study: (1) control, (2) hyperglycemic group (which got Streptozotocin (STZ) treatment but not NG treatment), and (3) hyperglycemic group (which got STZ treatment and 15% NG treatment) for three weeks. The T test results revealed notable variations before and after giving STZ. The finding indicated the blood glucose level before STZ induction in control was 86.50 ± 3.15 mg/dL, and the diabetic rat group (treated with STZ) was 87.60 ± 4.56 mg/dL. After STZ induction (7th day), there was a noteworthy rise in amount of glucose, namely 435.34 ± 120.33 mg/dL compare to the STZ treatment. The Duncan Multiple Range (DMRT) test showed there is no discernible difference between the STZ and NG treatments; however, there was a downward trend on days 14, 21, and 28. The conclusion of this study is that 15% NG has failed to decreas ehyperglycemia to normal blood glucose levels.
Counseling on The Importance of Maintaining Women's Reproductive Health In Arjasa Village, Arjasa Sub-District, Jember District Fajariyah, Susantin; Utami, Eva Tyas; Nihayah, Husnatun
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 3 No. 1 (2025): Mei
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v3i1.5487

Abstract

Women's reproductive health is an important aspect in maintaining community welfare, especially in preventing various diseases related to the reproductive organs. This counseling aims to increase the understanding and awareness of the community, especially mothers in Arjasa Village, about the importance of maintaining reproductive health. The method used in this activity is in the form of interactive counseling and discussion. The stages of service activities carried out: situation analysis, coordination with the village government, and implementation of activities. This activity involved 35 female participants aged 18-35 years, the majority of whom were housewives. The counseling material includes the definition of reproductive health, factors that affect it, common diseases, as well as prevention and early detection measures. The results of the activity showed that the participants had high enthusiasm in participating in the counseling, which could be seen from the active interaction during the question and answer session. The results of the activity showed a fairly good understanding of the counseling participants as seen from the enthusiasm of the participants in participating in the counseling and discussion sessions. The main obstacle in this activity was the limited time which caused some materials to be delivered briefly. Overall, this counseling has a positive impact in increasing awareness of women's reproductive health. It is expected that follow-up in the form of collaboration with village health cadres can continue to be carried out to maintain the reproductive health of the local community.