<![CDATA[Background: Hypertension is a condition where blood pressure increases from normal or reaches 140/90 mmHg. In Indonesia, the prevalence of hypertension has increased, especially in South Kalimantan. The use of antihypertensive drugs is necessary to control blood pressure and is used long term, but it often causes side effects that can affect the patient's quality of life. So it is necessary to monitor drug side effects to monitor unwanted reactions after administering the drug. Objective: To identify the characteristics of patients who experience side effects and identify the incidence of side effects of antihypertensive drugs. Methods: The method used in this research is descriptive observational with a cross sectional design, and the sampling technique uses purposive sampling technique. The data collection instrument uses an observational sheet. Results: Based on the research results, it shows that the majority of respondents were aged 56-65 years (36.08%), female (55.70%), had elementary school education (36.72%) and worked as farmers (36.70%). The most widely used antihypertensive drug was single Captopril (44.30%) and there were 110 respondents (69.62%) who experienced drug side effects in the form of dry cough (47.27), swelling (23.63%), dizziness (16 .36%) and itching (12.72%). Conclusion: Based on the results of research conducted on 158 respondents, 110 reported experiencing drug side effects. The most commonly reported side effects are dry cough, swelling, dizziness and itching]]>
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