Jurnal Ners
Vol. 10 No. 2 (2026)

Psychological Response to Chemotherapy: The Association Between Treatment Related Side Effects and Anxiety in Breast Cancer Patients

Hayatus Sa’adah Ayu Lestari (Universitas Lambung Mangkurat)
Yuza Olsi Rahmi (Universitas Lambung Mangkurat)
Tsuwaibatul Islamiyah (Universitas Lambung Mangkurat)
Rifda Nur Achriyana Arif (Universitas Lambung Mangkurat)
Muthmainnah Muthmainnah (Universitas Lambung Mangkurat)
Yohana Agustina (Universitas Lambung Mangkurat)
Priska Ekayanti Mahdiansyah (Universitas Lambung Mangkurat)



Article Info

Publish Date
23 Feb 2026

Abstract

Anxiety is a common emotional response among patients undergoing chemotherapy and may influence treatment adherence and quality of life. Understanding the association between chemotherapy side effects and anxiety is essential to support comprehensive cancer care. This study aimed to analyze the relationship between chemotherapy side effects and anxiety in breast cancer patients undergoing chemotherapy. This study employed a quantitative correlational method with a cross-sectional design. The research was conducted at Bangil Regional Hospital from November to December 2022. A total of 104 female breast cancer patients undergoing chemotherapy were selected using purposive sampling based on inclusion and exclusion criteria. Data were collected using two instruments: a chemotherapy side effects questionnaire adapted from Portenoy et al. (1994), and the Zung Self-Rating Anxiety Scale (SAS). The data were analyzed using spearman’s rank correlation. Chemotherapy side effects were predominantly classified in the mild category, with 66 respondents (63.5%) meanwhile, anxiety levels were mostly within the normal range, as reported by 68 respondents (65.4%). Spearman rank correlation analysis demonstrated a statistically significant positive relationship between chemotherapy side effects and anxiety (ρ = 0.335, p = 0.001). There is a statistically significant positive relationship between chemotherapy side effects and anxiety levels among breast cancer patients undergoing chemotherapy, indicating that greater severity of chemotherapy side effects is associated with higher levels of patient anxiety

Copyrights © 2026






Journal Info

Abbrev

ners

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing

Description

Fokus Jurnal Ners meliputi bidang kajian riset keperawatan diantaranya Keperawatan Medikal Bedah, Keperawatan Maternitas, Keperawatan Gawat Darurat, Keperawatan Anak, Keperawatan Lansia, Keperawatan Jiwa, Keperawatan Keluarga, Keperawatan Masyarakat, Manajemen Keperawatan dan Terapi Komplementer ...