Endometriosis significantly affects women’s sexual health, manifesting as pain and dyspareunia, which reduces quality of life. In Indonesia, hormonal and surgical interventions are both used to manage endometriosis. However, the study of their effect on sexual function among Indonesia’s population is still unclear. This quasi-experimental study included 60 women, divided into two groups based on the type of therapy. This study was conducted from June to September 2024 at the Department of Obstetrics and Gynecology, Dr. Moewardi General Hospital. Outcomes were assessed with the Female Sexual Function Index (FSFI) questionnaire, before and after treatment. The analysis showed the mean rank of the surgical intervention (44.97) is higher than the hormonal intervention (16.03). The Mann-Whitney U test revealed a significant difference between the two groups of intervention (p=0.000). These findings indicate that surgical intervention is superior to hormonal therapy in improving the FSFI score that reflects sexual function among women.
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