MPI (Media Pharmaceutica Indonesiana)
Vol. 8 No. 1 (2026): JUNE

Xanthine Oxidase Inhibitory and Antioxidant Activities of Kasumba Turate and Secang Extracts Combination

Malik, Abd. (Unknown)
Dahlia, Andi Amaliah (Unknown)
Handayani, Virsa (Unknown)
Widiastuti, Harti (Unknown)
San, Htoo Tint (Unknown)
Ahmad, Aktsar Roskiana (Unknown)



Article Info

Publish Date
30 Jun 2026

Abstract

Kasumba turate flower and Secang lignum have been commonly known as traditional medicinal widely grown in South Sulawesi. Both contain active constituents, including coloring agents such as carthamin in Kasumba turate and brazillin in Secang. These plants have been commonly used in traditional medicine to treat conditions such as high cholesterol, bacterial and viral infections, gout, and as antioxidants. Gout and high cholesterol are closely related. The combination of Kasumba turate and Secang extracts was intended to enhance activity. The evaluation of the xanthine oxidase inhibitor (XOD) and antioxidant activity (AO) was performed using the reducing uric acid and antioxidant FRAP methods. The XOD inhibitory study found that the extracts have activities as follow Sample A, B, C, and Allopurinol of 1.40; 2.1967; 2.24; and 1.39 μg/mL, respectively. The antioxidant capacity of Kasumba turate, Secang extract and their combination was 122.88; 17.36; and 197.31 μg/mL, respectively. We concluded that the combination did not increase the XOD inhibitory and antioxidant capacity. The Kasumba turate extract has the highest activity among the tested extracts.

Copyrights © 2026






Journal Info

Abbrev

MPI

Publisher

Subject

Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Media Pharmaceutica Indonesiana (MPI) is a journal focusing on pharmaceutical aspects. MPI is dedicated to update and support the development of information and knowledge on pharmaceutical fields. This journal is published twice a year (June and ...