<![CDATA[The doctrine of creatio ex nihilo is a fundamental teaching in Christian theology which affirms that God created all things out of nothing. This doctrine not only explains the metaphysical origin of the world but also carries important theological implications for understanding the relationship between God, humanity, and nature. This study aims to reexamine the doctrine of creatio ex nihilo within the framework of the theology of creation by emphasizing the relationship between God, human beings, and the natural world, as well as its implications for human responsibility toward creation. The research employs a qualitative approach using a library research method. The data sources include the Holy Scriptures, official Church documents, and works of classical and contemporary theologians that discuss the theology of creation. The analysis is conducted through a systematic theological approach using a critical and reflective theological analysis. The findings show that the doctrine of creatio ex nihilo affirms the ontological dependence of all creation on God as the source of being. This understanding highlights that the world possesses intrinsic value because it originates from God and therefore should not be treated merely as an object of exploitation. Within the framework of the theology of creation, human beings, as imago Dei, hold a unique position and bear moral responsibility to care for and preserve the integrity of creation. Therefore, the theological reflection on creatio ex nihilo provides an important foundation for the development of ecological ethics in Christian faith and enriches the understanding of the relationship between God, humanity, and the whole of creation in the context of the modern world.]]>
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