National soybean demand reaches 2.3 million tons per year, but domestic production is only around 800,000–900,000 tons with farmer productivity of 0.6–2.0 tons/ha, still below the potential of 2–3 tons/ha. Low yields are primarily influenced by inappropriate fertilization techniques, especially since most land in Southeast Sulawesi is nutrient-poor Ultisol. Productivity can be increased through a combination of biofertilizers, balanced inorganic fertilizers, and superior varieties. The effectiveness of biofertilizers is optimal when supported by local organic materials such as manure or agricultural waste, for example through the application of Biofresh. The purpose of this study was to determine the synergistic effect of Biofresh Plus biofertilizer and NPK inorganic fertilizer dosages on the productivity of several soybean varieties in Ultisol land. The research design used a split-plot design with the main factor being soybean varieties (Argomulyo, Anjasmoro, Dering-1, and Dena-1), and subplot factors in the form of fertilizer combinations: A1 (Biofresh + bokashi), A2 (Biofresh + bokashi + 25% NPK), A3 (Biofresh + bokashi + 50% NPK), and A4 (100% NPK). The treatment was repeated three times, resulting in 48 treatment units. The observed variables included the number of productive branches, the number of pods per plant, the weight of seeds per plant, the weight of 100 seeds, and the yield (ton ha⁻¹). The results showed that the synergy of biofresh, bokashi, and inorganic NPK fertilizers on various soybean varieties significantly affected the number of productive branches, the number of pods, the weight of seeds per plant, and the yield per hectare. The Dering-1 (Q3A3) variety treated with Biofresh, bokashi, and 50% of the recommended NPK dose provided the highest productivity, namely 2.40 tons ha⁻¹. Keywords: Plant Productivity, Soybeans Varieties, Biofresh, NPK, Ultisol
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