BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains
Vol. 9 No. 4 (2026): BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains

Pengaruh Pemberian Ekstrak Buah Gandaria terhadap Profil Darah Tikus yang Diinduksi Karbon Tetraklorida

Muhammad zaharul ichsan (Universitas Sumatera Utara)
syafruddin Ilyas (Universitas Sumatera Utara)
Masitta Tanjung (Universitas Sumatera Utara)



Article Info

Publish Date
31 Aug 2026

Abstract

This study aims to analyze the antioxidant potential of gandaria fruit extract against carbon tetrachloride-induced free radicals based on complete blood profile analysis in experimental animals. The method used was a completely randomized design with 30 rats divided into six treatment groups, namely normal, negative, positive, and three gandaria fruit extract treatment groups at doses of 200, 400, and 600 mg/kg BW. The results showed that gandaria fruit extract had a significant effect in improving blood profile damage after CCl4 induction, contained alkaloids, flavonoids, steroids, terpenoids, saponins, and tannins, had total phenolic content of 6133 mg/kg, antioxidant inhibition activity of 81%, and an IC50 value of 90 ppm. In conclusion, gandaria fruit extract at a dose of 600 mg/kg BW was the best dose and showed potential as a hematoprotective agent. Keywords: Blood Profile, Bouea Macrophylla, Carbon Tetrachloride, Plum Mango.

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Journal Info

Abbrev

BIOEDUSAINS

Publisher

Subject

Education

Description

Bioedusains: Jurnal Pendidikan Biologi dan Sains published by Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE) as an information and communication media for practitioners, researchers and academics who are interested in the field and development of biology ...