Change is inevitable in any organization, including within a hospital setting. As healthcare institutions, hospitals face various challenges regarding policy, technology, and public demands. This study aims to analyze the influence of organizational culture and transformational leadership on readiness to change, mediated by affective commitment, among nurses at a Class C hospital in South Jakarta. A quantitative, causal research approach was employed, involving 76 nurse respondents. A total sampling technique was used based on criteria established by the researcher. Data were collected via a questionnaire featuring four response options, and the data were analyzed using SEM-PLS. The results indicate that organizational culture, transformational leadership, and affective commitment each have a positive influence on readiness to change. Furthermore, both organizational culture and transformational leadership positively influence affective commitment. Affective commitment was found to mediate the effects of organizational culture and transformational leadership on readiness to change. Theoretical and managerial implications, as well as recommendations, are discussed in greater depth in the conclusion.
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