The Effect Of The Effectiveness Of Honey, Snakehead Fish Extract Albumin, And Honey Albumin In Inhibiting The Growth Of Escherichia Coli Bacteria

Dhamar Heksa Anggaet Saputra (Universitas Wijaya Kusuma Surabaya)
Sukma Sahadewa (Universitas Wijaya Kusuma Surabaya)
Nur Khamidah (Universitas Wijaya Kusuma Surabaya)
Kartika Ishartadiati (Universitas Wijaya Kusuma Surabaya)

Student Scientific Journal
Vol 4 No 4 (2026): October

Escherichia coli-related diarrhea remains a health problem and requires natural adjunctive alternatives. Objective: To compare the effectiveness of multiflora honey, snakehead fish albumin extract, and honey-albumin against Escherichia coli growth. This in vitro experiment used the well diffusion method in negative control, honey, albumin, and honey-albumin groups, each with nine replications; inhibition zone diameters were analyzed using the Kruskal-Wallis test and post hoc comparisons. The mean inhibition zones were 27.01 mm for honey-albumin, 26.46 mm for honey, 2.65 mm for albumin, and 0 mm for negative control, with a significant difference among groups (p < 0.001). Honey-albumin and honey effectively inhibited Escherichia coli, whereas albumin showed weak inhibition; honey-albumin had the highest descriptive value but did not differ significantly from honey.