<![CDATA[This study examines the role of Muhammadiyah as an agent of socio-political transformation in Minangkabau, a region characterized by the interaction between modernist Islamic movements and the cultural philosophy of Adat Basandi Syarak, Syarak Basandi Kitabullah. Using a qualitative approach through library research, this study analyzes academic literature, journal articles, and official organizational documents related to Muhammadiyahs activities in West Sumatra. The analysis is conducted using the perspectives of contemporary social movement theory, focusing on resource mobilization, political opportunity, and framing processes. The findings indicate that Muhammadiyah functions not only as a religious organization but also as a dynamic social movement that mobilizes institutional resources in education, health, and economic sectors to strengthen its social influence. Furthermore, Muhammadiyah strategically utilizes political opportunities without engaging in partisan politics and frames progressive Islamic values in harmony with Minangkabau cultural principles. This study concludes that Muhammadiyah in Minangkabau represents a form of Islamic social movement that successfully integrates faith, culture, and modernity in a balanced and transformative manner.]]>
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