<![CDATA[The development of Artificial Intelligence (AI) has increasingly driven changes in the management and development of Micro, Small, and Medium Enterprises (MSMEs) in Indonesia. This study aims to analyze the role of AI in driving organizational change in MSMEs through the aspects of AI readiness, reskilling, organizational agility, and innovation. The study employs a Systematic Literature Review (SLR) method with a descriptive qualitative approach to relevant national and international literature published during the 2020-2026 period. The findings indicate that the successful adoption of AI is determined not only by technological readiness but also by organizational readiness and human resource competencies. AI readiness and reskilling contribute to enhancing the ability of MSMEs to adapt to change, which subsequently strengthens organizational agility and supports innovation in products, processes, services, and business models. This review demonstrates that integrating AI with organizational readiness and human resource competency development can serve as a foundation for MSMEs to build competitive advantage and sustainability amid digital transformation. Therefore, AI should be viewed not merely as a technology but as a strategic capability that supports organizational change and the development of MSMEs.]]>
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