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Paediatrica Indonesiana

paediatrica-indonesiana
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Published by Ikatan Dokter Anak Indonesia

ISSN : 00309311 EISSN : 2338476X DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of health practice throughout the world.

Arjuna Subject : -

Articles 2,127 Documents

145 146 147 148 149

Genetic inheritance pattern in prurigo Hebra Siti Aisah Boediardja; Wahyuning Ramelan; Santoso Cornain
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

A study was conducted to analyze the multifactorial genetic inheritance pattern in prurigo Hebra (PH). Fiftyprobands (PH patients) consisting of 11 males and 39 females, with age ranged from 5-30 years were included in this study.A three-generation family tree was obtained from each subject, from which a total of 79 families were eligible for analysis. Foreach family the possible mode of inheritance, namely autosomal dominant (AD) or autosomal recessive (AR), was predicted.The families were then grouped according to the mode of inheritance. Analysis was conducted using Chi-square test,comparing the observed occurrence of PH and the expected value for each mode. To rule out mutation, the second methodwas applied, which only families with more than one affected child were analyzed, was used. The genetic inheritancepattern was not consistently compatible either with AR or AD. This finding, and other supporting facts, such as femalepreponderace, the role of HLA and the lower morbidity rate compared to the expected rate in AR or AD mode, indicated thatthe genetic inheritance of PH follows a multi-factorial pattern.

Hypoglycemia in preterm babies Incidence and risk factors Asril Aminullah; Dita Setiati; Sudigdo Sastroasmoro
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

Hypoglycemia is one of the most common problems in neonates, especially in preterm babies. Although in themajority of cases the outcome is good, symptomatic or asymptomatic hypoglycemia may give significant complications thatmay cause death or developmental delay later in life. We conducted a cross sectional study from September 5, 1999 throughMay 8, 2000 to identify factors associated with hypoglycemia in preterm babies treated at the Division of Perinatology, CiptoMangunkusumo Hospital, Jakarta. There were 112 babies included in the study, with the mean gestational age of 33.3 (range22 to 37, SD 4.2) weeks, and mean birth weight of 1801 (range 850 to 2440, SD 420) grams. Twenty-seven of the 112 infantsshowed hypoglycemia. Univariate analysis disclosed that birth weight, degree of perinatal asphyxia, small for gestational age(SGA), presence of respiratory distress syndrome, mothers with preeclampsia or eclampsia, and mothers who had intravenousinfusion of glucose during labor were significantly associated with hypoglycemia in preterm babies. Gestational age,meconium staining, or infant of diabetic mother were not significantly associated with neonatal hypoglycemia. On logisticregression analysis to control confounders we found that only the degree of perinatal asphyxia and small for gestational agewere associated with hypoglycemia in those preterm babies.

Management of vaccination - related anaphylaxis Ariyanto Harsono
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

Anaphylaxis is a systemic, immediate hypersensitivity reaction due to IgE mediated immunologic release ofmediators from mast cells and basophils. Features of severe condition are obstruction of the upper airway from tissueswelling, marked bronchospasm, and hypotension. In vaccination related anaphylaxis, optimal management begins withprevention: prevaccination screening including questions about possible allergy to any component of vaccine, and anticipationof anaphylaxis by observation at least 15 minutes following vaccination are very important. The essential treatment isprompt administration of adrenaline. Since hypotension is due to a shift of fluid from intravascular to extravascular space, themainstay of treatment should be the restoration of intravascular volume. Since anaphylaxis can be biphasic administration ofcorticosteroid in preventing late phase reaction can be postulated.

Development of children of 2 â€“ 3 years old from pre-prosperous family and prosperous family stage II Haris Marta Saputra; Sulaiman Yusuf; Noval Azis; Amir Syarifuddin; Bistok Saing
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

In this study we assess the condition of children development of 2-3 years of age in prosperous family, preprosperousfamily and prosperous family stage II, and find the related factors. This was a cross sectional study on 94children of pre-prosperous family and 94 children of prosperous family stage II at Medan Tuntungan district from December1998 up to March 1999. Data is obtained by questionnaires and examination of the developmental bases by Denver II Method.Statistical analysis of relationship between 2 qualitative variables is tested by chi-square. In the pre-prosperous family wefound 67 children with (35.6%) normal development and 27 (14.4%) children with abnormal development, on the prosperousfamily stage II there were 81 (43.1%) children with normal development and 13 (6.9%) children with abnormal development.We found significant difference between the children development of pre-prosperous and prosperous stage II (p<0.05),significant relationship between children development within 2-3 years of age and the parentsâ€™ education level of the Preprosperousfamily (p<0.05), and no significant relationship of the following factors: mothers employment status, motherâ€™sage, number of family and the childâ€™s order in the family.

Pulmonary tuberculosis in childhood nephrotic syndrome (A cross sectional study) Taralan Tambunan; Attila Dewanti; Bambang Madiyono; Nastiti N Rahayoe
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

Childhood tuberculosis persists as an important global health problem. Tuberculosis is one of the commonestimportant complications in children with nephrotic syndrome. Tuberculosis may interfere with the response to steroid therapyand is still being the commonest morbidity cause in children with nephrotic syndrome. To find out the prevalence, clinicalfeatures, and the impact of tuberculosis in children with nephrotic syndrome, a cross sectional study was conducted on 100nephrotic children consisted of 63 males and 37 females at the Cipto Mangunkusumo Hospital from April 1st to October 30th,1999. Pulmonary tuberculosis was detected on 15 cases ( 95% CI : 8% - 22% ) , consisted of 8 boys and 7 girls. Most of themaged 10 â€“ 16 years old (66,6%) and 86,7% were undernourished. The combination of clinical judgement, chest X-ray andMantoux test were helpful in establishing the diagnosis. The majority of tuberculosis cases (80%) were detected on frequentrelapsers and steroid dependent groups of the nephrotic syndrome. A significant correlation were noted in tuberculosis withundernutrition and unfavorable response to steroid (frequent relapser and steroid dependent cases).

A case of pediatric AIDS in Dr. Sutomo Hospital Surabaya, Indonesia Ismoedijanto Ismoedijanto; Rosanti Yustina; Rahayu Tri Lestari; Hidayat Burhan
Paediatrica Indonesiana Vol 41 No 3-4 (2001): March 2001
Publisher : Indonesian Pediatric Society

We report a 2-year old girl who suffered from HIV. The diagnosis was based on history, clinical findings, andlaboratory work-up. Suspicion of the presence of HIV was started when the girl continued to have wasting syndrom e withseveral focal infections unresponsice to ordinary treatment. The patient past away following severe diarrhea and apparentlysepsis.

Varicella antibody in healthy children Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 39 No 1-2 (1999): January - February 1999
Publisher : Indonesian Pediatric Society

Varicella is the most contagious viral exanthematous disease, which has a variable clinical course. We studied a seroepiderniologicaJ study on varicella antibody in 350 healthy children at Department of Child Health, Medical School, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta; from May to July 1998. The aim of this study was to get figures of varicella antibody in healthy chiJdren which can be used as a baseline data in the decision of recommendation in varicella vaccination. Subjects were 1-12 years old children with no history of varicella infection or immunization. The varicella antibody was determined by using Etisa assay (Enzygnost lest). Among 350 healthy children, 42.9% were males; they were divided into 3 age groups: 1-3, 4-7 and 8-12 years. Fourty two children (11.1 %) had seropositive varicella antibody (above protective level 0.2 mIU/ml). The prevalence of subclinical valicella significance increased with increasing age. Subjects with clinical or subclinical varicella had the same figure of age specific prevalence. The mean varicella antibody in each age group was almost similar. The minimum varicella antibody titer was quite similar between 1-3 and 4-7 age group, but not in 8-12 age group. Forty one percent had history of varicella contact, older chiildren had more history of contact.

Risk factors of upper gasterointestinal tract bleeding caused by stress ulcer Abdul Latief; Alan Roland Tumbelaka; Rulina Suradi; WEnny Lazdya Taifur
Paediatrica Indonesiana Vol 39 No 1-2 (1999): January - February 1999
Publisher : Indonesian Pediatric Society

During the period of December 1st 1997 until April 30th 1998, an observational study with cross sectional design was conducted at the Pediatric Intensive Care Unit (PICU). Risk factors of the occurrence of upper gastrointestinal tract bleeding (VGTB) on patients admitted to the PICU Medical School University of Indonesia/ Cipto Mangunkusumo Hospital were described analysed. Upper gastrointestinal tract bleeding was confirmed if there was evidence of brown or coffee ground material of the gastric fluid in the nasogastric or gastrotomy tube, hematemesis or melena, which was subsequently proved by benzidin test. Â The risk factors in this study was defined based on the risk factors found from previous studies i.e. shock, sepsis. severe head injury, multiple complication, liver insufficiency, pneumonia, respiratory failure, intervention during treatment (operation >3 hours, ventilator, corticosteroid >3 days). From 26 patients with UGTB risk factors in this study, 19 persons (73%) developed UGTB. The proportion of UGTS was not different on the patient's characteristic (age, sex, nutritional status). UGTB found were bleeding through nasogastric tube (58%) and occult bleeding 37%, hematemesis only one person (II %).The majority of VGTB occurred on the 3rd Â day of hospitalization (84%) and after ventilator usage of >48 hours (58%). Patient who underwent >3 hours operations were craniotomies. All the patients who received >3 days of corticosteroid (4 persons) developed VGTS.

Benefits of infant calendar action poster to improve the compliance of growth and development monitoring Sudiyanto Darmosubroto; Sudigdo Sastroasmoro; Rini Sekartini
Paediatrica Indonesiana Vol 39 No 1-2 (1999): January - February 1999
Publisher : Indonesian Pediatric Society

A community based study was conducted among infants between 0-12 months old about the compliance of growth and development monitoring, with the provision of infant calendar action postern. The subjects of study residing at Cipinang Cempedak areas,Mere fonowed-up from March 1997 until March 1998. One hundred infants providedÂ· with the action postern comprised the intervention group, and 100 infants not provided with the action posters comprised the non intervention or the control group. Twenty infants of the control group and 18 infants of the intervention group dropped out because they moved out areas or didn't show up at the subsequent visit. More than half of the parents has middle income with Rp 134,832.35 â€“ Rp 1,664,733.75 per month, 75.3% the fathers were employees of private enterprises. Eighty two of the intervention group (36 male infants or 43.9% and 46 female infants or 56.1 %) and 80 of the non intervention group d (39 male infants or 48.8 % and 41 female infants or 51.2%) participated in this study. The results showed that the compliance of periodical visits of growth and development monitoring of the intervention group was significantly better than that of the control group. Other results show that the intervention group got proper feeding, had adequate nutritional status, and had complete immunizations as recommended. And sustained contraceptive practice by the mothers.

Clinical aspects and white blood cell count in children with urinary tract infection Hendrik B. Tokan; Komang Kari
Paediatrica Indonesiana Vol 39 No 1-2 (1999): January - February 1999
Publisher : Indonesian Pediatric Society

The purpose of this study was to evaluate the clinical aspects and to count white blood cells in attempt to flnd simple parameters to predict urinary tract infection (UTI) prospectivecaly. Twenty four children with pyuria were studied, the history of clinical symptoms of urinary tract infection and blood leucocyte count were obtained. Local symptoms was the commonest symptom found in this study (87.5%), followed by fever (75.0%). If urine culture was taken as the gold standard, the predictive value of positive local symptoms with pyuria to urinary tract infection was 76.19%, sensitivity 88.88% and specificity 16.66%. The predictive value of history of fever with pyuria ti urinary tract infection was 76.47"10, sensitivity 72.22% and specificity 33.33%. The predictive value of leucocytosis with pyuria to urinary tract infection was 76.47%, sensitivity 72.22% and specivicity 33.33%. Meaning that the local symptoms, fever or leucocytosis with pyuria were not a good tool for the diagnosis of urinary tract infection, but probably useful as a screening procedure to distinguish the posibility of urinary treat infection.

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