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INDONESIA
Journal of Medical Biomedical and Applied Sciences
Published by Innovative Journal
ISSN : -     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Arjuna Subject : -
Articles 112 Documents
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Celiac Disease and Schizophrenia Richard P Conti, Jacqueline M Arnone,
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.12

Abstract

The relationship between schizophrenia and celiac disease (CD) has been reported in the research literature for over 70 years. CD is a T-cell mediated autoimmune inflammatory disease of the small intestine and is activated by the consumption of prolamins found in wheat, rye, oats or barley in genetically predisposed individuals. Incidence and prevalence rates for CD in the United States (US) are widespread, affecting 1% of the aggregate population in not at-risk groups, or1 out of 133 persons. Gluten, the trigger for CD and cause for damage to the lining of the small intestine, has been demonstrated to impair the nervous system. Neurologic disorders including ataxia, epilepsy and headache have been well documented in the literature. Psychiatric conditions including depression, anxiety and schizophrenia have also been studied with great interest among adults and children with CD. Additionally, impaired cognitive function has also been reported in individuals with CD and schizophrenia. Past and current studies on schizophrenia have demonstrated a reduction in psychotic symptoms following adherence to a gluten-free diet, however studies with smaller sample sizes showed no significant differences. Recommendations for future empirical research to further investigate the relationship between schizophrenia, cognitive function and CD are discussed.
Knowledge and Practices of Stroke Survivors Regarding Secondary Stroke Prevention, Khomas Region, Namibia Amukugo Hans Justus, Jachi Peter,
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.13

Abstract

The purpose of this study were in two fold namely to determine the knowledge, practices and, challenges as well as the information sources of stroke survivors and also educational practices by stroke management team with regard to secondary stroke prevention, Khomas Region, Namibia.A quantitative, descriptive and explorative design was used. Data was collected from (n=8) stroke management team members and (n=60) stroke survivors discharged stroke survivors from the Katutura State Hospital, in year 2012. Collected data was analysed using Epi Info statistical package version 5.3.1.Although the stroke management team participated in this study acknowledged that they played a role in the health education of stroke survivors with regard to prevention of secondary stroke, it appears that Knowledge and practice on secondary stroke prevention among stroke survivors is very low despite the availability information sources available. The study also revealed that half of the stroke survivors who participated in the study were unable to name a single appropriate action to take to prevent secondary stroke. A significant proportion of stroke survivors also continue to smoke and or consume alcohol contrary to expectations and recommendations. Only a relatively small percentage of stroke survivors comply with lifestyle changes prescribed to them such as diet modification and engaging in physical exercise.
A Two Stage Oxidative Decarboxylation of di carboxylic acid by Pyridiniumdichromate in perchloric acid media B K Dangarh, Shikha Soni, Shilpa Rathore
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.14

Abstract

Oxidation of di carboxylic acid viz- tartaric acid by pyridiniumdichromate (PDC) in perchloric acid medium has been studied. Active oxidizing species involved is protonated PDC. First order plot log (a-x) versus time is broken in two straight lines. Some induction period is also observed. Effect of concentration of substrate, PDC, HClO4, Mn (II), Ce (III) and ionic strength has been investigated. Thermodynamic parameters have been evaluated. Energy of activation is 53.14 and 56.58 kJ mol-1 for two successive stages of oxidation. Entropy of activation is low and negative. Although the activation energy does not correspond to C-C bond breaking, but the reaction products indicate C-C bond breaking. Suitable mechanism has been proposed involving complex formation.
Incidence and Non – Pharmacological Management of Dysmenorrhea Ernald Zeqja, Alma Imami Lelçaj, Robert Qirko,
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.15

Abstract

Aim: The aim of this study is to determine the prevalence of primary dysmenorrhea, its impact in life quality also non-pharmacological treatment methods. Method: This was a cross sectional study conducted in 2015. In this study participated 320 female students of the Faculty of Technical Medical Sciences, University of Medicine, Tirana, Albania. For the data collection was used a questionnaire. Results: The prevalence of primary dysmenorrhea was 85%. The severity of pain referred by students was: 50% moderate pain, 34% severe pain, and 16% mild pain. 51% of students don’t use drugs to relieve the menstrual pain, while 49% use painkiller. The medications used to treat or reduce the symptoms of dysmenorrhea were: 43% Acetaminophen, 41% Ibuprofen, 9% Mefenamic acid, 6% Aspirin and 2% Naproxen. Over 86% females included in this study, use self-management strategies for menstrual pain. Among the most used non-pharmacological strategies of self-management to reduce the pain were: sleeping 54 %, resting 47.4%, lie on one’s stomach 37.1 %, wearing loose garments 34.5 %, etc. Also resulted that the most affected activity by the dysmenorrhea were: concentration during classes 76.8%, daily activity 75.7%, and relations with friends 51.8%, social activity 50%, the family relationship 47.8%, test results 45.9%, school attendance 41.5% and participation in exams 23.5%.Conclusions: Dysmenorrhea and accompanying symptoms have a negative impact on a significant number of students by influencing their physical, social and the academic activity. Non-pharmacological methods should be promoted more and more because they are easy to use, cost effective and without adverse collateral effects.
Effect of Different Microbial Treatments on Germination, Seedling Growth and Other Quality Parameters of Maize (Zea mays L.) Dr. Anurag Titov, Azad Ahmad Wani,
Journal of Medical Biomedical and Applied Sciences Vol 3 (2016)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v3i0.16

Abstract

The cultivated species “Zea mays L.” belongs to family poaceae (Graminae) which is the fifth largest family consisting of 10,000 species and at least 600 genera, unquestionably the most important family providing majority of food. In the present study, the experiment pro-tray method was conducted at Krishi vigyan Kendra (KVK) Ujjain (M.P.) to find out the possible effects of different microbial seed treatments includes Phosphorus solubilizing bacteria (PSB), Trichoderma viride and Azatobacter on seed germination, seedling length, vigour index and its contributing characters and subsequent seed quality parameters of maize. These microbial inoculants were thoroughly mixed with compost @ 15g/Kg compost before sowing. Results of the study showed that all treatments significantly enhanced seed germination, seedling length, Seedling vigour, chlorophyll content and leaf area of maize. The highest germination percentage (83.8%), Shoot length (25.8%), Root length (10.1%), total seedling length (35.3cm), seedling dry weight (0.27mg), Seedling vigour index SV-I (3429 mg), Vigour index SV-II (26.3mg), Leaf area (16.35 cm2) and Chlorophyll content like Chl. a, Chl. b and Total chl. (0.4948 mg/g, 0.4521 mg/g and 0.9466mg/g) and other parameters were obtained in seeds treated with Phosphorus solubilizing bacteria (PSB) followed by Azatobacter and Trichoderma viride. Hence, the results suggested that seeds treated with these microbial treatments can be considered as efficient alternative bio-fertilizers to promote better seed quality in terms of germination percentage, shoot length, Root length, seedling length, seedling dry weight, vigour index, leaf area and chlorophyll content.
Modulation effect of Herbal extracts on the antibacterial activity of Tetracycline Bayor MT, Annan K, Gbedema SY, Adu F,
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.17

Abstract

As part of our ongoing study to screen local herbs for their possible usefulness in chemotherapy of infectious diseases, we assessed extracts from sixteen herbs for their antimicrobial properties and their influence on the activity of tetracycline. The minimum inhibito-ry concentrations (MIC) of tetracycline against Staph. aureus, B. subtilis, P. aeruginosa, E. coli and S. typhi were determined alone and in the presence of sub-inhibitory concentrations of the extracts by the Kirby–Bauer agar diffusion method of antibacterial assay. Twelve of the extracts potentiated the antibacterial activity of tetracycline against at least one of the test bacteria
Antihyperglycaemic and Hepatoprotective Effect of Phyllanthus Emblica Fruit in Diabetic Animal Model M, Mittal
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.18

Abstract

The present study is aimed to evaluate the antihyperglycemic activity of ethanolic extract of Phyllanthus emblica fruits in alloxan in-duced diabetic rats. Whistar rats were made made diabetic with alloxan and ethanolic extract of P.emblica is administred in a dose of 100mg/kg and 150mg/kg body weight for antidiabetic activity. Blood glucose levels were estimated in all groups on 0, 10th, 20th, 30th day of treatment with P.emblica. The cholesterol, triglycerides, AST, ALT, ALP were estimated on 30th day of treatment in all group compared against diabetic control group. The ethanolic extract of fruit of P.emblica 100mg/kg & 150 mg/kg body weight showed dose dependenent reduction in blood glucose level in alloxan induced diabetic rats, cholesterol, triglyceride and other hepatic markers are also reduced when treated with ethanolic extract of P.emblica in alloxan induced diabetic rats. 
Risk Factor Analysis for Cardiovascular Diseases in Pregeriatric Type 2 Diabetes Mellitus Subjects U, Iyer
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.19

Abstract

Pregeriatric type 2 diabetic subjects were enrolled to identify the various risk factors for cardiovascular diseas-es. The risk factors analysis on 120 diabetic subjects showed a high prevalence of overweight, obesity, abdo-minal obesity, hypertension and metabolic syndrome. Poor metabolic control as evident from HbA1c was seen in 60% of the diabetic subjects. Dyslipidemia was a common feature. Majority of the subjects had 4-8 risk fac-tors and the most prominent risk factors were overweight/obesity, abdominal obesity, hypertension and low HDL-C levels. The multiple risk factor scenario highlights the need to improve the lifestyle patterns of the pop-ulation to reduce the risk of cardiovascular diseases.
Randomized Double Blind Comparison of Two Brands of Clopidogrel in Inhibition of Platelet Aggregation AA, Azeemi
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.20

Abstract

To compare the anti platelet effects of locally manufactured clopidogrel with the anti platelet effect of clopido-grel manufactured by multinational pharmaceutical abroad.
Antioxidants of Eichhornia crassipes: The World’s Worst Aquatic Weed N, Lata
Journal of Medical Biomedical and Applied Sciences Vol 1 (2014)
Publisher : Journal of Medical Biomedical and Applied Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15520/.v1i0.21

Abstract

The recent revival of interest in plant medicines across the globe and consequent pressure on precious herbal resources, calls for the use of plants through scientific screening and validation. Free radicals and reactive oxygen species (ROS) have aroused significant interest among scientists in the past decades. Their broad range of effects on the biological systems causing various diseases has drawn attention of many experimental works. The world’s worst aquatic weed Eichhornia crassipes usually ranges from tropical desert to subtropical or warm temperate desert to rainforest zones. Ascorbic acid (vitamin C) one of the most extensively studied anti-oxidants has been detected in majority of plant cell types. Compounds of Quinones like anthraquinone considered to be a chemical antioxidant and possible therapeutic agents. Therefore, present investigation was planned to detect the presence of two bio-active compounds viz. Ascorbic acid and Quinones in the shoot and rhizome of Eichhornia crassipes by Thin Layer Chromatography (TLC) technique. The result obtained indicates that though plant is an aquatic weed is good services of phytochemicals needed for mainten-ance of good health, can also be exploited in manufacture of drugs. Its screening and scientific evaluation proves beneficial for the mankind along with the management of the plant.

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