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INDONESIA
Jurnal Biodjati
Published by Universitas Islam Negeri Sunan Gunung Djati Bandung
ISSN : 25481606     EISSN : 25414208     DOI : 10.15575/biodjati
Core Subject : Science,
Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences
Arjuna Subject : -
Articles 15 Documents
 1   2 
Search results for , issue "Vol 6, No 1 (2021): May" : 15 Documents clear
In Silico Activity Identification of Cyclo Peptide Alkaloids from Zizyphus Spina-Christi Species Against Sars-Cov-2 Main Protease Taufik Muhammad Fakih; Dwi Syah Fitra Ramadhan; Fitrianti Darusman
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10603

Abstract

The COVID-19 has spread worldwide and become an international pandemic. The promising target for drug discovery of COVID-19 was SARS-CoV-2 Main Protease (Mpro), that has been successfully crystallized along with its inhibitor. The discovery of peptide-based inhibitors may present better options than small molecules for inhibitor SARS-CoV-2 Mpro. Natural compounds have such a wide potential and still few explored, Zizyphus spina-christi is one of the medicinal plants that have many pharmacological activities and contains a peptide compound from alkaloids class, i.e. cyclopeptide alkaloids, that is interesting to explore as SARS-CoV-2 Mpro inhibitor. The compound structure was drawn and optimized using density functional theory 3-21G method. The protein chosen was the high resolution of SARS-CoV-2 MPro receptor (1.45 Å) with PDB ID: 6WNP, in complex with boceprevir. Molecular docking simulation was performed using Autodock4 with 100 numbers of GA run, the validation methods assessed by RMSD calculation. Furthermore, the prediction of pharmacological activity spectra was carried out using the PASS Prediction server. The results showed RMSD value was 1.98 Å, this docking method was valid. The binding energy of all compounds showed better results than the native ligand (Boceprevir). The in silico PASS prediction results indicated that all compounds showed antiviral activity. Some compounds showed protease inhibitory activity, i.e Ambiphibine-H, Franganine, and Mauritine-A, and the highest Pa (Predicted activity) value showed by Mauritine-A compounds. It can be concluded that the cyclopeptide compounds of Zizyphus spina-christi were indicated to have a potential as COVID-19 therapy targeting SARS-CoV-2 Mpro.
Bryophyte Diversity in Mount Prau, Blumah Village, Central Java Lianah Lianah; Niken Kusumarini; Fitriana Rochmah; Fadla Orsida; Mukhlisi Mukhlisi; Milya Ulfa Ahmad; Ainun Nadhifah
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.11693

Abstract

Bryophytes are a major component of the ecosystem in Indonesia. Due to their sensitiveness, the abundance and diversity of bryophytes in an ecosystem are influenced by environmental conditions. This study aimed to determine the diversity of bryophytes based on ecological parameters in the village of Blumah Kecaman Plantungan, Kendal Regency which is directly adjacent to the Mount Prau protected forest, Central Java. The data collection method used was the exploratory method and the descriptive exploratory method with survey techniques. Observation was carried out by exploring an area of  3 kilometers, every 1 km distance. An observation station was made consisting of station 1 Jiwan hamlet, station 2 Garung, and station 3 at Cengkek and Gondan springs. The specimens were identified based on taxonomic literature. Each species was collected as a specimen for further identification in the laboratory. Abiotic environment parameters such as temperature, humidity, altitude, light intensity, pH and slope were observed. The results showed that Blumah village still has high plant diversity, especially bryophytes. The more humid, the higher the place, the lower the temperature and light intensity, the more species diversity. Based on the identification results, 21 species were recorded, which includes 15 species of mosses, 4 species of liverworts, and 2 species of hornworts. The index value of bryophyte species diversity was in the medium category, and the index value of species richness and species dominance were at low levels.
RELATIONSHIP BUTTERFLY OF DIVERSITY (ORDO LEPIDOPTERA) WITH TROPICAL PLANTS IN THE MURIA MOUNTAIN KUDUS, CENTRAL JAVA Melisa Oktaviani Sukma; Lianah Lianah; Saifullah Hidayat
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10070

Abstract

The aims of this research is to know relationship betweef butterflies diversity and tropical flower plants in the Muria Mountain  at Kudus City of Central Java. The research use quadrat sampling transect method with three stations (along 2 km). Research was conducted in Maret and Juni 2020. The tools used insectnet, termohigrometer, luxmeter, digital camera,  rollmeter, GPS, jar and identification book. Data and analyzed for research using Shannon-Wiener index diversity (H’), Evenness index (E), Relative Abundance (Pi), Simpson Dominance Index (D), Density (KR) Frequency (FR), and Important Value Index (IVI).  Results of research showed that at least 40 species of 6 family butterflies at Mt. Muria. Survey results of Mt. Muria area has a middle Diversity, middle Evenness, and low dominance. Leptosia nina was the most relative abundance, frequency, density and INP highest species of butterflies. Butterflies were found frequently feeding on flower tropical plants. Two species of flower tropical plants was the most used of butterflies are Lantana camara, and Chromolaena odorata. Mt. Muria was optimal abiotic factors for butterflies habitat.
In Vitro Pancreatic Lipase Inhibitor Activity of Mangifera foetida Leaves Extract Oktira Roka Aji; Riris Asyhar Hudaya; Diah Asta Putri
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10646

Abstract

Obesity is a condition where there is excessive fat in the body. Weight loss can be accomplished by inhibiting fat absorption through the inhibition of pancreatic lipase activity, a key enzyme in fat metabolism. Natural products from plants contain various phytochemical compounds that can act as pancreatic lipase inhibitors. This research was conducted to determine the lipase inhibitor activity of the methanol extract of Mangifera foetida leaves. Mangifera foetida leaves were extracted and then the total phenolic and flavonoid levels were determined. The extract was tested for its ability to inhibit pancreatic lipase in vitro. The inhibitory activities of the extract and Orlistat were measured using p-nitrophenyl palmitate as a substrate at concentrations of 31.25, 62.5, 125, 250, and 500 µg/mL. The results showed that the extracts of young leaves (YL) and mature leaves (ML) contained phenol and flavonoid compounds. The IC50 values of young leaf extract (YL) and mature leaves (ML) were 45.22 and 35.50 µg/ml, respectively. In conclusion, the Mangifera foetida leaf extract can be promoted as a good source of anti-obesity compounds
Organic Waste as Fertilizer to Increase the Number of Peanuts (Arachis hypogaea L.) Flowers Enceng Sobari; Ferdi Fathurohman
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.6538

Abstract

Peanut has high economic value and a significant role in food needs. the national food supply needs for peanuts to date have not been sufficient. This study aimed to determine the effect of organic waste which in this case is mushroom baglog compost and sheep manure on the flowers and pods of peanuts. The study was conducted on March-July 2018 in Subang district using the simple experimental plot method and group-randomized factorial design with two factors with each treatment done triplicate. The first factor is the baglog compost (soil without baglog compost, 90 g/plants, 120 gr/plants); the second factor is sheep manure dose (without sheep fertilizer, 90 gr/ plants, 120 gr/plants). The results showed that the application of baglog compost and sheep manure fertilizer at concentrations of 90 g and 120 g, respectively increased the number of flowers and potential pods. Moreover, Sheep manure fertilizer at a concentration of  120 g/plant, increased the dry weight of pods, seed, and 100 seeds even though was not significant.
Bacterial Contamination at Whiteleg Shrimp (Litopeanaeus vannamei) in Aquaculture Mashuri Masri -; Eka Sukmawaty; Fatmawati Nur; Suriani Suriani
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.11812

Abstract

Indonesia has a very high biodiversity, which has later become one of the natural products of interest to the international community, including fishery products. One of the high-demand Indonesian fishery products is whiteleg shrimp Litopeaneus vannamei. However, safety food Exported whiteleg shrimp products must meet the criteria, including free from bacterial contamination such as Escherichia coli, Salmonella, Vibrio cholera. This study attemptted to analyze E. coli, Salmonella, V. cholerae contamination in 3 ponds in Bojo, Cilellang, and Palanro Village in District Malusetasi, Barru Regency, South Sulawesi. Two samplings for each pond were conducted in the morning were pond water and  fresh whiteleg shrimp. SNI 2728-2018 specifies the quality and safety requirements for fresh shrimp. This standard applies to whole or headless fresh shrimp handled from fresh shrimp and does not apply to fresh shrimp that has undergone further processing. Based on SNI 2728-2018, the E. coli test showed positive in Cilellang Village (sample A) with 11 MPN/g, negative in Palanro Village (sample B) and in Bojo village (sample C) with the value of <2 MPN/g. Escherichia coli test showed positive in sample D (Vannamei shrimp in Cilellang Village) and sample E (Vannamei shrimp in Palanro Village) with 2.0 MPN/g, 17 MPN/g, respectively. Only sample F (Vannamei shrimp in Bojo village ) showed a negative result. As for the Salmonella test, positive results showed in sample A, while sample B and sample C showed negative results. The Vibrio cholerae test showed negative at all samples. . This study concludes that Whiteleg shrimp from ponds in Mallusetasi District is classified as safe for consumption.
Habitat and Distribution Modeling of Prehistoric Hippos (Hippopotamus sivalensis spp.) During Pleistocene in Java Island Andriwibowo Andriwibowo; Adi Basukriadi; Erwin Nurdin
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10250

Abstract

Currently, there are only 2 extant species of hippos including common (Hippopotamus amphibius) and pygmy hippos (Choeropsis liberiensis) . But in prehistoric times, there were several species. During  Pleistocene these species were known to migrate to Java Island from Asian Continent and the species was Hippopotamus sivalensis spp. In this regard, this study aimed to model the habitat of H. sivalensis spp., ecology, and biodiversity of Hippopotamus sivalensis spp. based on the fossil record. The model was developed based on the Principal Component Analysis (PCA) method using the R statistical package. The results showed that there were 7 populations of H. sivalensis spp. that lived at various altitudes with an average of 177 m above sea level (95% CI : 123-232 m). According to PCA, there were at least 2 separate populations of H. sivalensis spp. One population occupies the forest while another occupies a habitat close to the coast. Currently the habitat for H. sivalensis spp. already changed. Based on habitat modeling, H. sivalensis spp. inhabit streams with submerged aquatic plants and shrubs and trees growing along river banks.
Morphological characteristic and Phenetic Relationship of Lysurus periphragmoides Collected from West Java Rudy Hermawan; Laifa Fusvita; Naufal Hafizh Nugraha; Mega Putri Amelya
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10724

Abstract

Lysurus is one of the unique genera in Basidiomycetes. It has a stinky odor and slime on the head. The unusual-shaped makes the species in Lysurus easily to be identified. One of Lysurus had been found in West Java, Indonesia namely L. periphragmoides. The specimen was deposited into Herbarium Bogoriense with code BO 24418. This study aimed to obtain specimens and characterize the Lysurus BO 24418 using morphological characteristics, and analyze the phenetic relationship among Lysurus species. Lysurus BO 24418 has two phases (egg and mushroom). The egg phase is usually hypogeous underground. The mushroom has a head and stem. The head bears the mature spore with slime distribute malodor. The stem has a hollow and spongy texture with a yellowish color. The numerical data of morphological characters of species in Lysurus were analyzed using NTSys ver 2.1 software. Ten characters were used to build a dendrogram using Sequential Agglomerative Hierarchical Nested (SAHN) cluster analysis with Unweighted Pair Group Method with Arithmetic Mean (UPGMA). Phallus indusiatus was selected as an outgroup. The analyses showed the specimen was classified as L. periphragmoides with 100% of similarity coefficient and it was close L. gardneri with 40,4% of similarity coefficient. The characters that cluster among them are stem surface, head type, egg diameter, and spore max length
Preliminary Study on Antibacterial Activity of Sawo Kecik (Manilkara kauki (L.) Dubard) Roots Extract Novida Pratiwi; Rini Retnosari; Sitoresmi Prabaningtyas
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.7708

Abstract

The roots of sawo kecik (Manilkara kauki (L.) Dubard) contain astringent that can be used to treat diarrhea for infants. However, the active antibacterial substance in sawo kecik roots has not been known. Therefore, the research to understand the antimicrobial activity of sawo kecik roots extract against Escherichia coli and Staphylococcus aureus was performed. Sawo kecik roots were macerated using methanol and chloroform. The result was then treated with E.coli and S.aureus with a concentration of 5 ppm and compared to negative control (solvent) and further observed and analyzed how reduced the bacterial growth with Two Ways ANOVA without interaction. The research results indicated that the sawo kecik roots methanol extract was effective to slow down the growth of S.aureus (0.160 ± 0.007) but ineffective against E.coli, whereas sawo kecik roots chloroform extract was not effective to reduce both bacteria. It can be concluded that further research is required to measure and verify the antibacterial activity of the extract using higher concentration samples and different research methodology.
The Ethnobotany Study of The Foodstuffs by Local Communities in The Bulumario Village, North Sumatera Marina Silalahi; Khairissa Trisliani Asmara; Nisyawati Nisyawati
Jurnal Biodjati Vol 6, No 1 (2021): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v6i1.10353

Abstract

Food is a primary human need. Various foods are initially obtained from plant species. Village people have used various food plants based on local knowledge and belief. The aims of this research were to elucidate (1) various food plants traditionally utilization by local people of the Bulumario Village, North Sumatra; (2) plant organs of food plants that are traditionally used by the local people of Bulumario village. The method used in this study was qualitative. Data were collected through surveys, interviews, and participatory observation. A total of 46 respondents were interviewed consisting of 22 men and 24 women who determined by purposive sampling. Data were analyzed was descriptively using descriptive statistics. A total of 83 species belonging to 66 genera and 36 families have been used by local communities in Bulumario village as foodstuffs. Those used as a source of carbohydrates (7 species), fruit sources (15 species), vegetables (32 species), and spices (21 species). Based on plant part used, the foodstuffs are fruit (34 species), leaves (21 species), and stems (13 species).  The composition of food plants are cultivated (53 species), wild (18 species), and semi-cultivated (12 species). Solanum torvum, Garcinia attrovidis, Etlingera elatior, and Zanthoxylum acanthopodium are spices especially in Bulumario Village which have bioactivity as an antimicrobial so they are potential to be developed as a natural preservative. Pakkat (Calamus hookerianus, Calamus metzianus, Calamus thwaitesii and Plectocomiopsis geminiflora) have the potential to be developed as a vegetable or carbohydrate source.

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