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Journal of Applied Pharmaceutical Research

joapr
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Published by Creative Pharma Assent

ISSN : - EISSN : 23480335 DOI : 10.18231

Core Subject : Health,

Medicine & Pharmacology

Journal of Applied Pharmaceutical Research (JOAPR) is an official publication of Creative Pharma Assent (CPA). It is an open access, peer review online international journal. JOAPR is primarily focused on multiple discipline of pharmaceutical sciences (Pharmaceutics, Pharmaceutical Technology, Biopharmaceutics, Cosmetic Technology, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Herbal drugs/ formulations, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest) which publish quarterly. JOAPR also includes evaluation of pharmaceutical excipients & their practical application to research & industry based efforts. The aim of the scientific journal, JOAPR is to present a wide area for the current researchers to share their noble works and ideas in terms of the research papers, review articles and short communications. JOAPR only publish the original research works with a definite innovation and novelty after thorough reviewing. The paper must have a suitable and proper scientific background.

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Articles 6 Documents

Search results for , issue "Vol. 5 No. 3 (2017)" : 6 Documents clear

Acne: current perspective Kamra, Manju; Diwan, Anupama
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

Acne vulgaris or acne is a multi factorial chronic inflammatory disease of pilosebaceous unit. Globally it affects approximately 9.4% of the population. It is characterized by blackheads and white heads, pinheads, large papules which may lead to scarring. Other than scarring, its main effects are psychological, such as distress and reduced self-esteem. Up to 80% of teenage girls and 90% of teenage boys are afflicted with acne. Adult acne, although less common than adolescent acne, is a significant problem for 3% to 6% of adult men and 5% to 12% of adult women. It is the most common chronic skin disorders which require urgent attention. Successful treatment of acne requires careful selection of anti-acne agents.

Screening of poly vinyl chloride degrading bacteria from plastic contaminated area of Baddi Kumar, Sahni; Teotia, U. V. S; Singh, Yogendra
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

Plastic wastes are posing ever increasing environmental concerns. Recent research works have shown that most of the constituents of plastics can be degraded by microbes and the film plastics can be treated by microbial systems. In this study, poly vinyl chloride (PVC), degrading bacteria’s were isolate and characterize from soil dumped with plastics. The PVC degradating bacterial were identified as E.Coli, Staphylococcus, Pseudomonas and Klebsiella. It was observed that maximum degradation by Pseudomonas and degradation after 10 months was 40.53%, 23.06%, 10.92% and 5.32% for Pseudomonas, Klebsiella, Staphylococcus and E.Coli respectively.This work concluded that soil contains bacteria’s that have ability to carry degradation of poly vinyl chloride (PVC)

Development and validation of stability indicating HPTLC method for estimation of dextromethorphan hydrobromide Gandhi, Santosh V; Dyandyan, Shubhangi K.
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

A simple, sensitive and accurate stability indicating HPTLC method has been developed and validated for estimation of Dextromethorphan hydrobromide in bulk and pharmaceutical dosage form. The drug was spotted on precoated silica gel 60 F254 aluminum plates using Toluene: Methanol: Triethylamine (8.5:1:0.5 v/v/v) as mobile phase. The retention factor (Rf) was found to be 0.60±1.92. The detection of band was carried at 225 nm. The drug was subjected to different stress conditions like acid, base, neutral hydrolysis, oxidation, thermal degradation and photolysis. The method was successfully validated according to ICH guidelines Q2 (R1). The data of linear regression analysis indicated a good linear relationship over the concentration range of 2000-20000 ng/band with correlation coefficient 0.991. The method found to be accurate as results of the recovery studies are close to 100 %. The developed method was found to be simple, sensitive, selective, accurate and repeatable for analysis of and can be adopted for routine analysis of drug in bulk and pharmaceutical dosage form

Nitrite contents in various masticatories prevailing in the state of Assam – a pilot study Bharadwaj, Rituraj; Barooah, Prajjalendra; Saikia, Snigdha; Haloi, Jayanta; Deka, Manab; Sahu, Bhanu P; Medhi, Subhas
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

Background: The habit of using masticatories is quite common among the population of the state Assam. There are numerous types of masticatories available throughout the state, most of which include areca nut in different forms, accompanied with beetle leaves and tobacco leaves and other associated substances added for flavor. Aim: To determine the level of nitrite present in different types of masticatories prevailing in the state. Materials & Methods: The classical Griess method was used for the estimation of nitrite in different types of these masticatories prevailing in the state Assam (n=35) using the basic diazotization principle and spectrophotometric determination. Statistical Analysis used: The results obtained were analyzed statistically by using SPSS V.16 software. Results: The result of the study indicate the amount of nitrite in different types of these masticatories, among which highest levels of nitrite was found in raw areca nut with beetle leaves without lime. The presence of lime decreases the amount of nitrite (p<0.05) whereas, the presence of beetle leaves and unprocessed areca nut increases the amount of nitrite (p<0.05) in the masticatories used by the people of the state. Conclusion: From the study conducted, it can be concluded that the presence of lime reduces the amount of nitrite in the masticatories, whereas the presence of beetle leaves and unprocessed areca nut contribute higher amount of nitrite in the masticatories

Development and evaluation of time controlled release tablet of ketoprofen for the treatment of Rheumatoid Arthritis Sharma, P H; Avari, J. G.
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

The aim of present study was to develop and evaluate time controlled release tablet of Ketoprofen intended for rheumatoid arthritis. The cardinal sign of rheumatoid arthritis are stiffness, swelling and pain of one or more joints of the body characteristically most severe in the morning. Rheumatoid arthritis shows a significant circadian variation in its symptoms. Time controlled release tablet delivers the drug at definite time or in controlled rate. It consist of core tablet coated with two layers, the inner swelling layer and outer rupturable. Before compression of core tablet, drug- excipients compatibility study and precompression parameters were investigated. Core tablet was prepared by direct compression method. The core tablets are coated with crosscarmellose sodium as inner swelling layer with different coating level. The prepared tablet again evaluated and coated with rupturable layer of ethylcellulose. The free film of ethylcellulose was evaluated for various parameters. The effect of microcrystalline cellulose and coating level of rupturable layer and swellable layer on lag time were investigated. The results shows as the amount of microcrystalline cellulose increase in core tablet the lag time decreases. The lag time increases with increase in coating level of swelling layer and rupturable layer. The water uptake study shows that higher ethylcellulose levels retards the water uptake and prolongs the lag time.

Evaluation of phytochemical parameters, antibacterial and antihelminthic activity of leaves and bark extracts of plant Bombax ceiba Shah, Suyogya; Ghimire, Kamana; Gupta, Amit Kumar; Pokhrel, Priyanka; Banerjee, Janmajoy; Khanal, Hemanta; Pradhananga, Mahalaxmi
Journal of Applied Pharmaceutical Research Vol. 5 No. 3 (2017)
Publisher : Creative Pharma Assent

Bombax ceiba, commonly known as the red silk-cotton tree, is a large, briefly deciduous tree occurring in warm monsoon forests in southern Asia. Various phytochemical constituents present in different plant parts has been already reported earlier to possess many biological activities, here in this work extraction was performed by mixture of solvent (distilled water: ethanol) as well as the individual solvents (water) and (ethanol). The phytochemical screening of the leaves and barks was found to exhibit the presence of carbohydrates, glycoside, saponin, phytosterol phenol, tannins, flavonoid, proteins and diterpenes and negative result for alkaloids in all the solvent extracts. The ethanolic extract of leaves was subjected to antihelmenthic activity and the result was found to be moderate

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-

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Journal Mail Official
japr.editor@gmail.com

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Plot No. 105/42, Opposite electricity sub station, Changorabhata, Raipur (Chhattisgarh), India 492001

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INDONESIA