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Rachmat Kosman
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As-syifaa Jurnal Farmasi
Published by Universitas Muslim Indonesia
ISSN : 20854714     EISSN : 25029444     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, Pharmaceutical Chemistry, Drug Discovery, Pharmacokinetics, Pharmaceutical Biology, Community and Clinical Pharmacy, Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI" : 12 Documents clear
UJI AKTIVITAS ANTIOKSIDAN ISOLAT FUNGI ENDOFIT DAUN GALING-GALING (Cayratia trifolia L.) DENGAN METODE 1,1-DIPHENYL-2-PICRYLHYDRAZIL (DPPH) Magfirah Abdullah; Fitriana Fitriana; St. Maryam
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.617

Abstract

Endophytic fungi generally produce secondary metabolites that have beneficial biological activities such as anticancer, antiviral, antibacterial or antioxidant compounds. The aim of this study was to examine the antioxidant activity of galling-galing leaf endophytic fungi isolate (Cayratia trifolia L.) by 1,1-diphenyl-2-picrylhydrazil (DPPH) method. This study used IDGG-03 endophytic fungi isolate fermented for 21 days using MYB medium then extracted and evaporation was carried out. The fermentate extract obtained was then tested qualitatively and quantitatively for antioxidant activity. Qualitative results using TLC plates indicate that galling-leaf fungi isolates have antioxidant activity which is characterized by the presence of yellow spots on a purple background. And in the quantitative test IC50 68,133 µg / mL was obtained, which indicated the antioxidant activity of galling-vane leaf endophytic fungi isolate (Cayratia trifolia L.) classified as a strong antioxidant.
FORMULASI DAN EVALUASI FISIK SEDIAAN KAPSUL EKSTRAK DAUN CINCAU HIJAU (Cyclea barbata Miers ) SEBAGAI ANTI INFLAMASI Fitria Wulandari; Fitri Wahyu Widyawati; Khusnul Rizaldi; Fauzia Ningrum Syaputri
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.638

Abstract

One of the Indonesian plants that can be used is green grass jelly leaf (Cyclea barbata Miers) because it contains alkaloids, polyphenols, saponins and flavonoids that can prevent inflammation. Inflammation is an environmental physiological response caused by damage or damage to the tissue that functions, reduces, or confines an injuring agent or injured tissue. The purpose of this study was to formulate green grass jelly leaf extract into anti-inflammatory capsules. This research begins with the maceration of the simplicia extraction process of green grass jelly leaves using ethanol 96% solvent. Granule preparation used dry granulation method with vivapur 101 which varied in 3 formulas, namely (1: 1, 1: 1,5, 1: 2). The next step was a physical evaluation test of granules including moisture content, flow properties, angle of rest, carcass index, compressible density and true density and a physical evaluation test including organoleptic test, weight uniformity and disintegration time. The results of the evaluation test that have been carried out show that formula 3 with a thick extract concentration: vivapur 101 (1: 2) is the most optimal, because it meets the evaluation test requirements with a moisture content value of dry extract granules 1.5% and a water content value of granule capsules. green grass jelly leaves 1.1%.
PROFIL SOSIODEMOGRAFI DAN TERAPI ANTIRETROVIRAL PADA PASIEN HIV/AIDS RAWAT JALAN RSUD RADEN MATTAHER JAMBI PERIODE TAHUN 2017-2018 Jelly Permatasari; Muhammad Budi; Indri Meirista
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.627

Abstract

As a result of the decline in the immune system it is very susceptible to various diseases (opportunistic Infections) that can be prevented by the presence of antiretroviral therapy with various complications. Sociodemographic Profile is a human picture related to the purpose of the study, Sociodemographic research in HIV / AIDS patients is still rarely found, therefore Sociodemographic Profile is important to know as a basis for information that can be used to prevent transmission of HIV / AIDS. The purpose of this study was to determine the Sociodemographic Profile and ARV therapy in outpatient HIV / AIDS patients at Raden Mattaher Jambi Hospital in the 2017-2018 period. This research method is descriptive by retrospectively collecting data from medical record data. The results showed in the Age group 26-35 years (41.94%), Male sex (70.97%), the last high school education (61.29%), Employee / Private employment history (54.84%) , based on the highest transmission Heterosexual (84.95%), with Marital marital status (83.87%), based on the highest HIV / AIDS status namely HIV (94.62%). Based on ARV therapy, most combinations of Efavirens + Lamivudin + Tenofovir (59.14%).
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN INFEKSI SALURAN PERNAFASAN DI PUSKESMAS RAWAT JALAN KECAMATAN SIULAK MUKAI KABUPATEN KERINCI TAHUN 2018 Rasmala Dewi; Deny Sutrisno; Andral Pramirta
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.626

Abstract

Respiratory infections a major health problem that is commonly found in Indonesia. The height prevalence of respiratory tract infections and their effects have consequences high consumption of over the counter medicines and antibiotics. This research aims to evaluating the use of antibiotics which includes the right patient, the right indication of the drug, the right dose, and the interaction of the drug in patients with respiratory infections in outpatien health centers in the district of Siulak Mukai in Kerinci District in 2018. This study is a observational research is descriptive in nature by collecting data on records medical outpatients retrospectively according to age inclusion criteria 25 years, patients with a diagnosis of respiratory tract infections in outpatient health centers in the district of Siulak Mukai, Kerinci Regency in 2018, complete medical record data and analyzed with the guidelines of Pharmaceutucal Care 2005 with descriptive methods. The results of evaluating the use of antibiotics in patients with respiratory tract infections in outpatient clinics in the district of Siulak Mukai in Kerinci Regency in 2018, showed that 100 % apporopriate treaments, as well as the incidence of antibiotic drug interactions by 2 events.
UJI AKTIVITAS EKSTRAK ETIL ASETAT DAUN KAYU JAWA (Lannea coromandelic (Houtt.) Merr.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA TIKUS PUTIH (Rattus norvegicus) Bayu Putra; Safriani Rahman
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.720

Abstract

Wound healing is a process of repairing skin and soft tissue when these organs are injured. One of the plants that are presumed to affect wound healing is Kayu Jawa (Lannea coromandelic (Houtt.) Merr.). This research aims to determine the healing effect of burns and the effective dose of ethyl acetate extract of Kayu Jawa’s leaves. The animal test that has been induced using a hot plate with temperature 100oC stuck at the back of mice were divided into 5 (five) groups. Group 1 Na.CMC as Negative control, Group 2 Lanakeloid-E as Positive control, Group III, IV, and V were extract ethyl acetate of Kayu Jawa’s leaves (Lannea coromandelic (Houtt.) Merr) with 3 dosage variations namely, 75 mg/kg, 150 mg/kg, and 300 mg/kg were given topically 2 times a day for 21 days. Then wound area measure using calipers. The group with 300 mg/kg dosage has the best effect for reducing wound area of burns, with statistical value not significantly different from the comparison group (Lanakeloid-E) with a percentage value of 84%.
PROFIL KADAR GLUKOSA DARAH PASIEN DIABETES MELLITUS TIPE 2 YANG MENGGUNAKAN ATORVASTATIN 20 MG DI RUMAH SAKIT MADANI, ANUTAPURA DAN UNDATA PERIODE 2015-2019 Lestari, Widya; Mukaddas, Alwiyah
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.607

Abstract

Atorvastatin is one of the lipophilic statins that can cause diabetes through some mechanisms, such as liphophilic properties, it’s activities to insulin secretion, insulin signaling, and adiponectin levels. The purpose of this research is to know demographic data, profile of when blood sugar levels, and the time needed for atorvastatin to increase blood sugar when type 2 diabetes mellitus patients use atorvastatin for 20 mg. This research is observational descriptive research with retrospective data collection approach by looking at the usage of atorvastatin, with total samples 22 patients obtained from medical record data at Madani hospital, Anutapura and Undata in Palu in the period of 2015-2019. This research result shows that the demographic data of the average age of type 2 diabetes mellitus patients in which complications of dysplidemia that uses atorvastatin for 20 mg are in the age of 45-56 years old, female gender (57.14%), with the last education of Senior High School (38.09%) and occupation as Government Employees (33.33%), the time needed for atorvastatin 20 mg to increase blood sugar is 2 months (the difference is 26.38 mg/dl; percentage 19.52%) and the percentage of highest blood sugar increase is one year, which is 93.91%.
UJI EFEKTIVITAS EKSTRAK ETANOL KULIT PISANG MAS (Musa acuminata Colla) TERHADAP PENURUNAN KADAR KOLESTEROL TIKUS (Rattus norvegicus) HIPERLIPIDEMIA Sukmawati, Sukmawati; Wati, Aulia; Asmaliani, Ira; Meilinda, Mega
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.645

Abstract

Hyperlipidemia is the escalation level of cholesterol and triglyceride in blood. Lady finger banana peel had chemical flavonoid, tanin, and saponin contents having the activity to reduce cholesterol level. The research aimed to determine the effect of cholesterol level reduction of ethanol exctract of lady finger peel on hyperlipidemia rat. The research used twenty rats divided into five groups. Group I (negative control) was given Na. CMC of 1% b/v, group II (positive control) was given simvastatin of 1,023 mg/kgBW, group III, IV, V groups were given the extract of 500 mg/kgBW 1000 mg/kgBW, and 1500 mg/kgBW. The rats were fed a high dietary fat during treatment and induces with pristine cholesterol for twenty one days. The measurement of rat cholesterol level was conducted on day 0, 22 and 36. The result were statistically processed using One Way Anova proceeded to Post Hoc Bonferroni. The result of the research showed that the positive control group had no different tangible effect to ethanol extract of lady finger banana groups (p>0,5). In conclusion, the ethanol extract of lady finger banana had the activity in reducing cholesterol level with effective doses of 500 mg/kgBW, 1000 mg/kgBW, and 1500 mg/kgBW.
EVALUASI PENGGUNAAN ANTIBIOTIK DENGAN METODE ATC/DDD DAN DU 90% DI PUSKESMAS AUR DURI KOTA JAMBI PERIODE 2016-2018 Andriani, Yuni; Martua, Aris Sahat; Andriani, Medi
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.628

Abstract

Introduction: Since 23 years ago, WHO transferred ATC (Chemical Therapeutic Chemical) and DDD (Defined Daily Dose) as a global standard for the study of drug use, one of which is antibiotics. Drug Use Method 90% (DU 90%) method that shows the grouping of drugs that fall into the 90% category of use that is often used in conjunction with an analysis of the use of ATC / DDD drugs. Research Objectives: determine the use of antibiotics in Aur Duri Health Center in Jambi City based on the ATC / DDD method and DU 90% for the 2016-2018 period. Research Methods: Retrospective data collection using ATC / DDD and DU 90% methods. Results: Of the four types of antibiotics, the highest DDD value was obtained at Aur Duri Health Center for the period of 2016-2018, namely amoxicillin antibiotics. Antibiotics that entered the DU 90% segment at Aur Duri Health Center based on data for the 2016-2018 period were amoxicillin, ciprofloxacin and tetracycline. The most quantitative data using the ATC / DDD method is amoxicillin with the highest number of 39.39 DDD / 1000 KPRJ / Year in Aur Duri Puskesmas in 2017.
ANALISIS KADAR FENOLIK FRAKSI ETIL ASETAT DAUN PETAI CINA (Leucaena leucocephala) (Lam.) de Wit) SECARA SPEKTROFOTOMETRI Uv-Vis Sari, Intan Purnama; Abidin, Zainal; Maryam, St
Jurnal Ilmiah As-Syifaa Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.681

Abstract

Traditionally, river tamarind leaves (Leucaena leucocephala (Lam.) De Wit.) can be used as medicine for injuries, swollen, diarrhea and also as antiseptic. The river tamarind leaves contains several main compounds such as alkaloids, saponins, flavonoids, phenols, mimosine, lectin, protein, oil, calcium, phosphorus, iron, vitamin A and vitamin B. The research aimed to determine the phenolic levels found in the ethyl acetate fraction of the leaves. The extraction was done by maceration method using ethanol 96% then fractionated with ethyl acetate solvent. The obtained fraction was analysed by UV-Vis spectrophotometry method at the maximum wavelength of 761 nm using gallic acid as a standard. Based on the qualitative test, river tamarind leaves positively contained phenolic. The phenolic compound contained in the ethyl acetate fraction was 0.176 mgGAE/g in that every gram of ethyl acetate fraction had phenolic of 0.176 mg equivalent to garlic acid.
IDENTIFIKASI MEDICATION ERROR PADA RESEP PASIEN PEDIATRI di PALU INDONESIA Firdayanti Firdayanti; Amelia Rumi
As-Syifaa Jurnal Farmasi Vol 12, No 2 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v12i2.635

Abstract

 Medication error is an event that is detrimental to the patient and can also endanger the safety of the patient, occurring as long as the patient is in a preventable health care workforce. This research aims to determine the form and percentage of medication error on prescription pediatric patients aged 2 months – 18 years in one of the hospitals in the city of Palu, Indoenesia. This research is a descriptive cross-sectional research with data retrieval conducted prospectively with the total sampling method. The sample of this study has 118 prescription paediatric patients in the period of September to October 2019. With the results of the research medication error in the prescribing  phase ie no SIP doctor 92.37%, no high patients 92.37%, no weight 90.67%, no age of the patient 72.88%, no medical record number 64.40%, no dosage form 58.47. Phase of transcribing error is no patient status 81.65%, no age of the patient 72.88%, no apparent medical record number 59.32%, not clear the dosage form of 53.38%. The dispensing error is a 61.86% incorrect or incomplete tag. The administration error phase of the patient is not given an explanation about the cure 66.10%%, it can be concluded that it has been medication error in one of the hospitals in the city of Palu, Indonesia

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