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INDONESIA
Berkala Ilmiah Kedokteran Duta Wacana
Published by Universitas Kristen Duta Wacana
ISSN : 24609684     EISSN : 24768863     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Ilmiah Kedokteran Duta Wacana is a Scientific Journal to publish medical research articles, and other scientific medical articles from Medical Faculty of Duta Wacana Christian University academic community and also receive articles from other resources with appropriate and related topics. The policies taken for the largest composition of articles are the results of research, but can also receive scientific articles in the form of literature review and case reports. To maintain the quality of writing, Berkala Ilmiah Kedokteran Duta Wacana also cooperate with other Medical Education Institutions, especially in the recruitment of reviewer partner to conduct a "review" of all incoming articles. Funding for publication is entirely sourced from the Faculty of Medicine and also from Duta Wacana Christian University.
Arjuna Subject : -
Articles 161 Documents
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THE EFFECT OF A TRIPOD CANE ON THE FUNCTIONAL MOBILITY OF PATIENTS WITH KNEE OSTEOARTHRITIS Nelson Sudiyono
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.164

Abstract

Background: Canes have been recommended as walking aids for knee osteoarthritis to reduce the loading on the affected knee. Patients are usually recommended to hold the cane in the contralateral hand to the affected knee. Nevertheless, some patients prefer to hold the cane ipsilateral to the affected knee. However, the effect of using ipsilateral or contralateral tripod cane on functional mobility in patients with knee osteoarthritis is still unknown Objective: To compare the immediate effect of ipsilateral and contralateral tripod cane usage on functional mobility in patients with symptomatic knee osteoarthritis Method: This cross-sectional study involved 30 overweight or obese patients with symptomatic unilateral or bilateral knee osteoarthritis (Kellgren Lawrence grade 2 and 3) who never use a cane. Functional mobility was evaluated with Time Up and Go test in three conditions; without walking aid, with tripod cane contralateral and ipsilateral to the more painful knee. Results: The TUG time of aid-free walking is 4.75 (p < 0.001, 95% CI 3.79 - 5.71) seconds faster than ipsilateral cane use and 6.69 (p < 0.001, 95%CI 5.35 - 8.03) seconds faster than contralateral cane use. The TUG time of ipsilateral cane use is 1,94 (95% CI, 1.13 - 2.79) seconds faster than contralateral. Conclusion: Patients with symptomatic knee OA who use tripod cane ipsilateral to the more painful knee have higher functional mobility than the contralateral.
ARSITEKTUR JAMINAN KESEHATAN INDONESIA: CAPAIAN, KRITIK DAN TANTANGAN MASA DEPAN (THE ARCHITECTURE OF INDONESIAN HEALTH INSURANCE: ACHIEVEMENT, CRITIQUE, AND FUTURE CHALLENGE) Silvester Hari Purnomo
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.173

Abstract

This book has thoroughly described the achievements, critiques, and challenges in the future of the Indonesian health insurance architecture. The author describes his vision of the ideal universal health coverage (UHC) for the country impeccably. His experience as a general practitioner and public health practitioner since the early days of national insurance establishment has shaped his writing style. The author opens with an introduction to the principles of health insurance, such as the aggregation of funds and insurance risks. He also describes the health insurance scheme in various countries before discussing Indonesia’s situation. The historical development of Indonesian health insurance is aptly presented. Its concepts, albeit under frequent changes are presented as though they have already manifested in architecture. Detailed programmes of the national health insurance, which is organised by BPJS Kesehatan (Badan Penyelenggara Jaminan Sosial Kesehatan) are presented with its challenges and difficulties. The frequent adjustment of fund collection and service payment scheme (e.g. the utilisation of case-based group method to replace the diagnosis-related group in service payment scheme) is also described thoroughly. Outstanding claim with a lag of payment time to the service providers is another example of the system shortcoming mentioned in this book. The author emphasises on the breadth of primary care coverage which includes government-owned primary health care centred and private general practitioners’ clinics. Regardless of the valuable information on the national insurance scheme, there is a lack of the definition and the systematic description of the “architecture” terminology. The readers might need a further picture of the dynamics of a new-born UHC system. The book seems to be directed to the general readers, yet placing more sophisticated knowledge which suitable for higher education students from health or medical discipline. This warrants further clarification on the scope of the audience and reorganises the contents accordingly. There is a potential for utilisation for educational purposes, where the chapter organisation may be modified to the number of periodic class sessions, including a chapter dedicated to changing issues and future challenges. The author has incorporated actual data, visualised in various graphs. However, the print quality is lacking so the readers might difficult to interpret them. The general population needs enticing figures, while the academic audience would prefer detailed graphics and data tabulation. In addition, there are important changes in the insurance policy between print date and this review, such as the significant change in insurance premium. This issue is quite important to be added in the future revisions. The reviewer deems the book important. The book itself has its own architecture, achievement, critiques, and challenges. Despite the effort to reach readers from the general population, the medical and health finance policy students would be the most benefited audience. This book is a good introduction to more advanced topics in the health insurance discipline, with routine revisions on dynamic changes in Indonesian healthcare insurance architecture.
OPTIMAL CONDITION FOR MULTIPLEX POLYMERASE CHAIN REACTION (PCR) IN DETECTING ASCARIS LUMBRICOIDES, TRICHURIS TRICHIURA, AND NECATOR AMERICANUS IN PRESERVED STOOL Christiane Marlene Sooai; Elsa Herdiana M; Supargiyono Supargiyono
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.171

Abstract

Background: Multiplex PCR examination is one of the molecular examination methodologies applied to detect soil-transmitted helminth (STH) infection. Optimization of the multiplex PCR method is a complex process, but it is necessary to obtain both a correct detection process and a satisfactory DNA product. Objective: To determine whether multiplex PCR can be optimized to diagnose STH from Indonesian isolates, and to find the optimal method for detection of A. lumbricoides, T. trichiura, and N. americanus infections in stool that have been stored for 3 years. Methods: A total of 15 samples were examined, and these samples were previously examined by using a microscopic method, then continued with optimization steps. Result: The optimal PCR mixture used primers targeting COI gene for A. lumbricoides, 18S rDNA for T. trichiura and ITS1 for N. americanus, 15 µl of Go Taq Green Master Mix, 5 µl of the 3 pairs of primers, 5 µl of DNA template and 4 µl of DdH2O, and the condition was 30 minutes of 950C denaturation, 30 second of 530C annealing and 1 minute of 720C extension, repeated for 35 cycles. Conclusion: Multiplex PCR can be optimized for STH detection from Indonesian isolates. The successful detection using the multiplex PCR method was influenced by sample preparation prior to DNA isolation, which includes several steps i.e. homogenization of samples using bead beaters and passing samples on liquid nitrogen rapidly.
ADVANCE DIAGNOSTICS TO RESOLVE INTRICATE AND NEGLECTED HEALTH PROBLEMS IN INDONESIA Teguh Kristian Perdamaian
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.187

Abstract

We are proud to present the first full English edition of BIKDW starting from this fifth volume in 2020. In this issue, we present articles on the utilisation of medical technology for daily clinical practice, and research on preventive medicine
CAPTURING TUBERCULAR MENINGITIS PROGRESSION IN CHILDREN WITH MULTI-SLICED COMPUTED TOMOGRAPHY (MSCT) SCAN: A PROSPECTIVE CASE REPORT Sherlyta Revania Ranuh
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.161

Abstract

Background: Tubercular meningitis in children poses a diagnostic challenge, either for its detection and follow-up. Neuroimaging is essential in the diagnosis process and early identification of complication or sequelae. Computed tomography (CT) scan is widely available in secondary and tertiary hospitals in Indonesia, which would improve the management of paediatric tubercular meningitis case. Objective: To describe the clinical progression of a child with tubercular meningitis from detection to sequelae at Bethesda Hospital, Yogyakarta. Case description: A 7-year-old boy was admitted to the emergency unit with acute headache, vomiting, and prolonged fever. Tuberculosis transmission indicated from the mother, which on TB treatment. Non-contrast multi-sliced computed tomography (MSCT) scan was performed on the first-day admission, on the 8th day of admission, before and after VP-shunt procedure for life-threatening hydrocephalus and the follow-up. There was an obvious disease progression shown by CT scan from the early stage, the onset of hydrocephalus, deteriorating hydrocephalus, and post-VP-shunt procedure. The periventricular infarct extended over time, concordant with worsening symptoms. Conclusion: Paediatric tubercular meningitis diagnosis relies on accurate neuroimaging studies to identify the specific sign. In the disease progression, the sign as early as slight hyperdensity should lead to meningitis diagnosis, and earlier treatment of hydrocephalus might prevent further debilitating sequelae or even fatal complications of tubercular meningitis.
DIFFUSE-WEIGHTED MAGNETIC RESONANCE IMAGING (DW-MRI) FOR CRYPTOGENIC STROKE DIAGNOSIS IN YOUNG ADULT FEMALE: A CASE REPORT Lothar Matheus Manson Vanende Silalahi
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 1 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i1.165

Abstract

Background: Ischaemic stroke is caused by various aetiology. Cryptogenic stroke diagnosis is established when no aetiologies are discovered although clinical manifestations are consistent with acute stroke. Diffusion-weighted magnetic resonance imaging (DW-MRI) is one neuroimaging modalities which could be useful in exploring aetiology instead of excluding intracranial haemorrhage. There are many conflicting pieces of evidence of the benefit using DW-MRI to confirm the presence or the absence of brain lesions. Objective: To report a clinical case of ischemic stroke with negative evaluation on advanced neuroimaging studies (DW-MRI). Case Description: A female, 35 years old, presented to the emergency unit with a 6 hours history of prickling sensation before admission. There were no risk factors of stroke, and no other neurological symptoms. The neurologic examination reveals left hemihypesthesia, with normal results on laboratory examination for stroke risk factors and negative ischemic lesion on brain DW-MRI. Explorative examination on cardiac aetiologies was negative. Patient was given a standard regimen for acute stroke management despite the negative results and established as a cryptogenic stroke case. Conclusion: Diagnosis of ischemic stroke should rely mainly on clinical findings, with consideration of cryptogenic stroke when there is no aetiology found after thorough examination. Nevertheless, comprehensive examination on cardiac function and coagulation tests should be performed whenever possible to determine the cause of ischaemic stroke.
THE RELATIONSHIP OF CERVICAL VERTEBRAL MATURATION (CVM) STAGE AND ANTEROPOSTERIOR FACIAL DIMENSIONS IN INDONESIAN POPULATION MAHINDRA AWWALUDIN ROMDLON; Setiadi W Logamarta; Yulia Anggraeni
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.179

Abstract

Background: Growth and development are two different but interrelated and difficult to separate factors. The growth spurt in boys is different from girls. Facial growth is closely related to overall body growth, one of which is the growth of the cervical vertebrae. Objective: The objective of this study was to determine the anteroposterior dimensions of the face based on the maturation levels of cervical vertebrae in 12-14 years old children. Method: Quantitative research using an analytic observational method with a cross-sectional approach was conducted on 21 boys and 21 girls. Measurement of anteroposterior facial length (S-A' and PTM-A) and assessment of cervical vertebral bone maturation level using the Hassel and Farman method. Results: Independent t-test results showed that there was a significant difference (p
APPROPRIATE LABORATORY AND IMAGING APPROACH FOR EARLY DIAGNOSIS IN HOSPITAL SETTING Teguh Kristian Perdamaian
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.240

Abstract

The main objective of global health is to reduce preventable death equally throughout the world. One important strategy is primary prevention through health promotion and early detection. Early diagnosis is defined as several methods to determine in patients the nature of a disease or disorder at its early stage of progression. In a referral health system, such as Indonesia, early diagnosis could be implemented both in primary care and secondary or tertiary referral hospital. Primary care centres screens fatal diseases, such as cancer and cardiovascular risk factors, mostly in asymptomatic patients with identified risk of having the diseases. Accordingly, the early detection programme has been designed for large population in a community setting. It is uncommon for hospitals in Indonesia applying primary prevention where most of the patients are referred with at least a couple of differential diagnoses. Subsequently, early diagnosis in hospital setting would be defined either as accelerating the diagnosis confirmation or detecting any uncommon findings on patients with atypical presentation. In some situation, early detection of life-threatening condition at hospital would prolong or even prevent death. Aside from accurate history taking and comprehensive physical examination, advance laboratory procedure and imaging might assist in early detection at hospital setting. This time, our issue presents case reports on the benefit of early detection in the management of rare disease, anaemia, and COVID-19 pandemic among patients without symptoms or with atypical presentation. In developed countries, most of known congenital diseases were screened prenatally or immediately after delivery. The most common practice in Indonesia is a regular prenatal ultrasound and through physical examination of the baby in their first week. However, this approach would still miss many rare diseases with delayed presentation such as Legg-Calve-Perthes Diseases (LCPD). Pradyana and Astuti1 discussed a paediatric case of LCPD highlighting the difficulty in diagnosis confirmation on a limp gait symptom. Serial imaging not only important in case follow-up, but also to detect newly existing abnormalities which verify the presence of LCPD. Iron deficiency anaemia (IDA) primarily affects women and children in Indonesia. Currently, school-based screening of haemoglobin in teenage girls could prevent the sequalae of IDA through iron supplementation. Early detection in anaemia would determine the presence of IDA before the declined haemoglobin. Recently, international investigators discovered novel biomarker to detect the presence of IDA in asymptomatic patients. Fenty described the potential of using reticulocyte haemoglobin equivalent (Ret-He) to characterize IDA amongst asymptomatic patients in hospital settings.2 This approach would be beneficial for screening purpose in high-risk population, both in community and hospital setting. During COVID-19 pandemic, early diagnosis is a necessity to reduce the infection rate with early quarantine. However, challenging situation might come in patients with atypical presentation, such as gastritis. Widiastana et al describe the later COVID positive result on patients with gastritis which nonresponsive to general treatment.2 The patients did not have any classical signs and symptoms of COVID-19, hence in the community, misdiagnosis of similar condition might exacerbate the rising infection cases.
A REVIEW OF QUALITY CONTROL IN HISTOCHEMISTRY AND IMMUNOHISTOCHEMISTRY STAINING Yustina Nuke Ardiyan
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.180

Abstract

Background: Tissue staining methods need controls to give best quality results. Controls is necessary to support the validity, correctness, and reliability of the staining results. Haematoxylin and Eosin (HE) and immunohistochemistry (IHC) staining require different control quality. Objective: To discuss the utilization of controls used in tissue staining. Method: This is a narrative review with literature from 2008-2016. Results: Routine staining usually does not require any control. Specific stainings require controls to support the validity, correctness, and reliability of the staining results. Histochemistry staining requires only positive control, while positive and negative controls must be included in IHC staining. A tissue section which expresses the protein of interest is reffered to positive control, whereas those without any target antigen expression are defined as negative control. Conclusion: Histochemistry and IHC staining controls are needed to obtain the validity of the tissue or cell samples.
SERIAL IMAGING OF A CHILD WITH LEGG-CALVE-PERTHES DISEASE AT BETHESDA HOSPITAL, YOGYAKARTA: A CASE REPORT Jourdy Kharisma Pradnyana
Berkala Ilmiah Kedokteran Duta Wacana Vol 5, No 2 (2020): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v5i2.162

Abstract

Background: Legg-Calve-Perthes disease (LCPD) is a rare condition of idiopathic avascular necrosis of the femoral head, mostly affects children under fifteen old. Most cases only affect one femoral head; bilateral involvement only occurs in about 15% of cases. Early diagnosis and prompt intervention play an important role in the prognosis to prevent degenerative damage on the bones and joints. Objective: To describe a case of Legg-Calve-Perthes disease in a 9-year-old boy in Bethesda Hospital, Yogyakarta. Case Description: A 9-year-old boy came with one month history of worsening pelvic pain to Bethesda Hospital, Yogyakarta. He also showed limping and limited mobility. Initial imaging studies did not find any abnormalities. Further follow-up with MSCT scan related to the complaint of persistent pain showed defects of left hip joint indicating Legg-Calve-Perthes disease. The patient undergone skin traction treatment which shows modest improvement on serial radiographic examinations during hospital admission. Conclusion: The rarity of LCPD warrant thorough imaging studies on children with unexplainable severe hip joint pain. Treatment should be initiated as early as possible after diagnosis to prevent further bone damage and worsening prognosis. Conservative management with skin traction would benefit the patient in restoring normal anatomy and optimal joint congruence to prevent degenerative damage to the joints.

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