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Berkala Ilmiah Kedokteran Duta Wacana
Published by Universitas Kristen Duta Wacana
ISSN : 24609684     EISSN : 24768863     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Berkala Ilmiah Kedokteran Duta Wacana is a Scientific Journal to publish medical research articles, and other scientific medical articles from Medical Faculty of Duta Wacana Christian University academic community and also receive articles from other resources with appropriate and related topics. The policies taken for the largest composition of articles are the results of research, but can also receive scientific articles in the form of literature review and case reports. To maintain the quality of writing, Berkala Ilmiah Kedokteran Duta Wacana also cooperate with other Medical Education Institutions, especially in the recruitment of reviewer partner to conduct a "review" of all incoming articles. Funding for publication is entirely sourced from the Faculty of Medicine and also from Duta Wacana Christian University.
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Articles 161 Documents
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COVID-19 MANIFESTATION IN A CHILD WITH LUNG METASTASES OF OSTEOSARCOMA: A CASE REPORT Yulwhinar Cego Saputra
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 1 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i1.232

Abstract

Background: COVID-19 (Corona virus disease-19) is an infectious disease caused by a new type of corona virus which in the same group of the virus that causes Severe Acute Respiratory Syndrome (SARS), where the incubation period for infection is 1-14 days or up to 24 days, accompanied by symptoms of a respiratory tract infection and other organ systems. The number of recent cases in November 2020 was 59.8 million worldwide. Elderly patients and people with comorbid diseases are at high risk of developing severe manifestations of this viral infection. Osteosarcoma is a deadly bone cancer that often causes patients to die from metastases to the lungs Purpose: The purpose of this study is to report cases of COVID-19 in a 9-year old child patient with a history of osteosarcoma at Bethesda Hospital Yogyakarta. Case Description: A 9-year old female patient came to the emergency room complaining of fever, cough, severe chest pain, and shortness of breath since 3 weeks before being admitted to the hospital. The patient had a past medical history of osteosarcoma since 1.5 years before being admitted to the hospital and an amputation procedure on the right arm was carried out, no specific illness in the family history was found. The general condition of the patient appears to be moderate with delirium consciousness (E4V6M1). Vital sign examination showed a pulse rate of 130 beats per minute, an oxygen saturation of 85% and a breath rate of 30 beats per minute. CT scan without contrast shows a massive left pleural effusion, malignancy/metastatic mass of the left lung, with pneumonic opacity in the right lung. Conclusion: COVID-19 is an infectious disease caused by SARS-CoV-2 and causes severe manifestations in patients with comorbid diseases including pulmonary metastases. CT-Scan modalities are used as a basis for diagnosis other than RT-PCR. Management of COVID-19 is in the form of supportive therapy based on the degree of disease severity.
ABCC8 EXON 16-3 C>T POLYMORPHISM IS ASSOCIATED WITH INSULIN SECRETION IN PATIENTS WITH TYPE 2 DIABETES IN YOGYAKARTA Johana puspasari Dwi Pratiwi
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 1 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i1.251

Abstract

Background ABCC8 is a gene encoding the SUR1 subunit of the KATP Channel which plays a central role in insulin secretion from the beta cell, hence its potential as the candidate risk gene in the development of type 2 Diabetes Mellitus (DM type 2). the polmorphism of ABCC8 exon 16 -3 C>T has been investigated in various populations with inconsistent result. Therefore, this study aimed to explore the association of the polymorphism with DM type 2 in Yogyakarta population. Method a number of 40 patients with DM type 2 and 44 patients without DM type 2 were recruited as case and control subjects, respectively. the polymorphism was genotyped using PCR-RFLP. The association between insulin secretion and the polymorphism was analyzed with ANOVA and Post Hoc Test. Chi-square and odds ratio were employed to determine whether the polymorphism was a risk of DM type 2. Results There was a significant difference between CC and CT genotypes among subjects with DM type 2 (p=0,005). Fasting insulin concentration exhibited a significant difference between CC and TT genotypes among DM type 2 subjects (p=0,013). Allele T frequency was found to be 0,45 among DM type 2 subjects and 0,48 among non DM subjects, there was no significant difference of allele T frequency between DM type 2 and non DM subjects (p=0,723, OR=0,90, CI: 0,49-1,65). Conclusion ABCC8 exon 16 -3 C>T polymorphism was not associated with DM type 2 prevalency in Yogyakarta population, however the impact of the polymorphism on diabetes pathogenesis in DM type 2 can not be excluded because of the association with insulin secretion in DM type 2 subjects.
CARA MUDAH MERAWAT LUKA (AN EASY WAY TO CARE FOR WOUNDS) Yacobus Christian Prasetyo
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.461

Abstract

Merupakan resensi buku Cara Mudah Merawat Luka.
Case Report Tuberculous Spondylitis in Elderly with Polyneuropathy Isabella Diah Ayu Laraswati; Lie Adityo Hansen
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.272

Abstract

Background Tuberculous (TB) spondylitis or Pott’s Disease is a manifestation of extrapulmonary tuberculosis infection caused by the hematogenous and lymphomatous spread of Mycobacterium Tuberculosis, causing infection in the vertebral bones. Approximately 10% of extrapulmonary TB cases are TB spondylitis. Pulmonary and extrapulmonary tuberculosis cases are considerable cases in developing countries. Indonesia is a country with the third-highest prevalence of TB in the world after China and India.Objective The aim of this study was to report a case of TB spondylitis in a 66 years old woman with polyneuropathy at Bethesda Hospital Yogyakarta.Case description A 66 years old female patient presented with complaints of pain and difficulty in moving the left lower limb 3 months ago. The patient had a history of hypertension 5 years ago, while the family history was not specific. The patient was generally in pain with full awareness and cooperation. Vital sign examination showed blood pressure 140/80 mmHg, pulse 82 beats per minute, and respiratory rate of 22 breaths per minute. The lumbosacral-MRI examination was performed without contrast material and L2-L5 TB Spondylitis, with L2-L3 Disc protrusion, was found.Conclusion Tuberculous spondylitis (TB) may cause paradiscal inflammation, edema, and progressive bone destruction due to lysis of anterior bone tissue and secondary ischemia which will lead to collapse. Pain, difficulty moving, and local swelling are the most common complaints. Abnormalities in the curvature, misalignment of the vertebrae, deformity and bone destruction might be found in MRI radiological imaging. Treatment of TB spondylitis prioritizes administering of anti-TB drugs combined with immobilization using a girdle. The prognosis for TB spondylitis varies depending on the clinical manifestations.
BIOFILMS AND ANTIBIOTIC RESISTANCE Tejo Jayadi
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.464

Abstract

The physician and health practitioner’s attention and alertness to biofilm existence and the consequences of biofilm in the biotic and abiotic environment are important to improve hygiene practice, rational antibiotic prescription, controlling the spread and emergence of emergency antibiotic resistance in healthcare facilities and community. The majority of chronic persistence and recurrent infection because of antibiotic resistance is biofilm infection, so needed precision and power alternative approach of management and therapy.
Case Report Chest Non-contrast ct-scan findings and follow up a patient suspected covid-19 infection Ngesti Chintia Dewi; Sutaryanu Dermoredjo Dermoredjo
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.274

Abstract

Background Covid-19 is an infection caused by SARS-CoV-2. Chest X-Ray (CXR) examination doesn’t show the radiographiccharacteristic of Covid-19 infection. Thorax CT-Scan is the gold standard imaging for pneumonia Covid-19 infection.Aim The purpose of this report is to describe a case of bronchopneumonia in a male patient aged 48 years old at Bethesda Hospital Yogyakarta during the Covid-19 pandemic.Case Description A 48 years old male patient came to the Bethesda Hospital in Yogyakarta with a complaint of fever 1 week before being hospitalized. The patient also complained of cough, sore throat, rhinorrhea, shortness of breath, malaise, and decreased appetite. The rapid test result shows SARS-CoV2 IgM and IgG (+), PCR swab Covid-19 results (+). Bronchopneumonia was concluded by CXR examination and chest non-contrast CT-Scan showed Covid-19 infection imaging characteristics. Later on, the patient showed clinical and radiological improvement.Conclusion Covid-19 is an infection caused by the SARS-CoV-2. Common symptoms are fever, cough, sore throat, shortness of breath, and malaise. CXR examinations on patients with Covid-19 infection show images of pneumonia, in this case, bronchopneumonia was concluded. CT-scan shows characteristic imaging of Covid-19 infection can support the decision on regular ward admission versus ICU and for follow-up in regular ward admission.
Inhibitive Properties of Anredera Cordifolia Extract on Escherichia Coli Swimming Motility Alexander Tobias Kristanto; Maria Silvia Merry; Suryani Hutomo
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.304

Abstract

Background Escherichia coli, a Gram-negative bacterium, is one of the main etiology of urinary tract infection (UTI). An important pathogenicity factor influencing biofilm production is its motility, swimming, or swarming. Anredera cordifolia (AC) leaves have been proven to have an antibacterial effect on various Gram-positive and Gram-negative bacteria, including E. coli.Objective To determine the effect of AC leaves extract on swimming motility property of E. coli derived from UTI patients. Methods AC leaves were extracted with the maceration method. E. coli was identified and isolated from UTI patients. There are4 diluting concentrations of AC leaves extract (from 875 mg per ml to 7000 mg per ml) and one negative control. The preparation underwent incubation, inoculation, and re-incubation. Swimming motility was measured manually, and the result was tested for significant difference between each dose with one-way ANOVA (limit of significance is 0.05)Results On AC leaves extract concentration of 1750 mg per ml, the swimming motility has been inhibited significantly compared to negative control and lower concentration of 875 mg per ml (0.543 cm vs 1.673 cm and 1.358 cm, respectively; p < 0.001). Increasing concentration (3500 mg per ml and 7000 mg per ml) did not show a significant difference in inhibition compared to 1750 mg per ml (0.539 cm and 0.530 vs 0.543).Conclusion AC leaves extract with a concentration of at least 1750 mg per ml would inhibit the swimming motility of E. Coli derived from UTI patients.
Vitamin D Status In Epileptic Adults With Valproic Acid Therapy At The Neurology Clinic, Diponegoro National Hospital, Semarang Santoso Jaeri; Adelia Putri Maharani; Dwi Ngestiningsih; Arinta Puspita Wati; Hasna Syariva
Berkala Ilmiah Kedokteran Duta Wacana Vol. 6 No. 2 (2021): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v6i2.431

Abstract

Background Epilepsy is a brain disease characterized by repeated unprovoked seizures at least two times with an interval of more than 24 hours between the first seizure and subsequent seizures. Valproic acid is an anti-seizure drug. Long-term use of valproic acid may be associated with metabolic disorders such as weight gain, and lipid profile changes, including vitamin D levels.Objectives To determine the correlation between the duration of valproic acid therapy and serum vitamin D levels in adults using valproic acid.Methods An observational analytic study with a cross-sectional design. The demographic and duration of valproic acid use were determined using questioner, and the serum vitamin D levels were measured using the ELISA method. The normality test was carried out using the Shapiro-Wilk test and then continued with the Pearson test to determine the correlation between the duration of valproic acid therapy and serum vitamin D levels. The results showed significance if the p-value <0.05.Results The mean serum vitamin D level among subjects was low (16.44+4,24 ng/mL), furthermore, there is no significant correlation between the duration of valproic acid therapy and serum vitamin D levels (p=0.956, r=-0,011).Conclusion There is vitamin D deficiency among adults with epilepsy but, the duration of valproic acid therapy does not correlate with serum vitamin D levels.
MEDICAL CLERKSHIPS' PERCEPTION AND FACTORS IN ACQUISITION OF KNOWLEDGE AND SKILLS DURING COVID-19 PANDEMIC Oscar Gilang Purnajati; Fransisca Galuh Widowati; Haryo Dimasto Kristianto
Berkala Ilmiah Kedokteran Duta Wacana Vol. 7 No. 1 (2022): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v7i1.475

Abstract

Background The global COVID-19 pandemic has changed Medical Education in general. Many changing policies are a challenge, and we must evaluate the results. Medical clerkship program presents a challenge of its own. Delay in rotation time, work restrictions, and reduced contact with patients can cause a lack of accuracy and realism in integrating knowledge and skills that should be the outcome of this clerkship.Objective We need to explore the impact of COVID-19 pandemic in clinical rotation in general perception and the factors that influence the acquisition of knowledge and skills in medical clerkship education.Method A qualitative study by comparing 2 groups, before pandemic and during pandemic group and explores the factors that influence the acquisition of knowledge and skills through focus group discussions (FGD).Results Conclusion The general perception obtained in this study included workload and knowledge acquisition, and the specific factors that influenced the acquisition of knowledge and skills were the existence of role models, feedback, and teaching and learning models during the pandemic.Conclusion The COVID-19 pandemic did not significantly affect knowledge acquisition of medical clerkship, but it had some effect on skill acquisition. Specific factors that influenced medical clerkship learning during this pandemic were role modelling and teaching-learning because of reduced face-to-face session between the clinical supervisors and the student. The feedback factor was almost not affected.
Obesity Genetics Hendi Wicaksono
Berkala Ilmiah Kedokteran Duta Wacana Vol. 7 No. 1 (2022): BERKALA ILMIAH KEDOKTERAN DUTA WACANA
Publisher : Faculty of Medicine Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/bikdw.v7i1.531

Abstract

Obesity is a health problem that become burden all over the world, and  affected all age groups. An increase in body weight above normal often characterises it. Genetic and environmental factors are known to be the main cause of obesity. Based on several studies, it turns out that genetic factors play a role of 40-60% in the incidence, however the role of genetic factors in obesity still not fully explained. The author wrote the topic of genetics and obesity based on his research experience regarding genotype polymorphisms associated with obesity. The aim of this book is to provide a new perspective on genetic factors as a causal factor and how genetics plays a role in obesity.

Page 12 of 17 | Total Record : 161

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