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JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
Published by Universitas Gadjah Mada
ISSN : 20888139     EISSN : 24432946     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
JMPF is the first open access journal in Indonesia specialized in both research of pharmaceutical management and pharmacy practice. Articles submitted in JMPF are peer reviewed, we accept review articles and original research articles with no submission/publication fees. JMPF receives manuscripts in both English (preferably) and Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. JMPF is also open for various fields such as pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, goverment policies related to pharmacy, and pharmaceutical care.
Arjuna Subject : -
Articles 6 Documents
 1 
Search results for , issue "Vol 7, No 4" : 6 Documents clear
Analysis of Drug Management Influence with the Success of Theraphy on Members of Pandangdia Community Patients with Diabetes Mellitus Umi Athiyah; Abdul Rahem
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33345

Abstract

Drug management is essential in quality and efficacy assurance, especially to achieve therapeutic outcome of chronic diseases; such as Diabetes mellitus. This study was observational and cross-sectional. The objective of this study was to analyze the influence of drug management towards achievement of therapeutic outcome amongs patients with diabetes mellitus. Thirty-five patients (members of a community of diabetic patients in Bangkalan) were voluntarily involved in this study as respondents. A validated and reliable questionnaire was used to collect the data. The result showed that appropriate drug use and proper drug storage influenced achievement of therapeutic outcome. While, place to get medicines and infomation resource had no correlation with achievement of therapeutic outcome.
Evaluation of Oral Antidiabetic Dosing and Drug Interactions in Type 2 Diabetic Patients Nova Hasani Furdiyanti; Fania Putri Luhurningtyas; Ratna Sari; Yulianti Yulianti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33263

Abstract

Indonesia is listed as the country with the highest type 2 diabetes mellitus patients number 4 in the world. Accuracy of treatment is necessary in the success of therapy for type 2 diabetes mellitus patients. Inaccurate dosage or drug interaction events can lead to treatment failure or even cause adverse effects in patients. Patients with type 2 diabetes mellitus usually have comorbidities that tend to get therapy with many drugs, thus increasing the risk of drug interactions. Drug interactions with oral antidiabetes are known to exist that can be life-threatening. The aim of this research is to know the accuracy of dose of oral antidiabetika drug and drug interaction event in type 2 diabetes mellitus patient. This research is a descriptive retrospective observational study. Data collection is done retrospectively, and sampling method is purposive sampling. Research subjects were all inpatients of type 2 diabetes mellitus 26 - 65 years old, who received oral antidiabetes therapy period 2016 at RS Sultan Agung Semarang, and meet the criteria of inclusion and exclusion. The data analyzed the incidence of drug interaction and dosage accuracy (based on dose parameter and frequency of administration). The results of the study in 86 subjects showed that the most widely used single therapy was metformin (50,98%) while the most used combination therapy was metformin and glimepiride (57,14%) .The incidence of drug interaction was 5%, between glimepiride and aspirin with a pharmacokinetic mechanism occurring in 4 patients. The percentage of inaccurate doses of oral antidiabetic drugs was 3.5%, which occurred in patients taking metformin and acarbose.
Evaluation of Antihypertension Drugs on Patients Diabetes Mellitus in RSI Sultan Agung Semarang 2016 Dian Oktianti; Nurul Fitria Dewi; Meiji Pujiawati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33342

Abstract

More than 50% of patients with type 2 diabetes mellitus are associated with hypertension. Uncontrolled blood pressure in patients with type 2 diabetes mellitus correlated with the onset of cardiovascular and cerebrovascular complications. Therefore, proper blood pressure management is needed to delay and prevent complications. Selection of appropriate antihypertensive drugs along with appropriate doses is one way to inhibit the possibility of complications. The purpose of this study is to know about the accuracy of the use of antihypertensive drugs and doses used. This research is a descriptive and observational retrospective research. The subjects of the study were 88 patients with diabetes mellitus with accompanying hypertension. Data taken include antihypertensive, antidiabetes mellitus, laboratory data. The data obtained are then analyzed descriptively using JNC edition 8 and DIH 2015. The results showed that there were 88 samples meeting the inclusion and exclusion criteria. The commonly used single antihypertensive group is Angiotensin Receptor Blocker (ARB) of 56.09%, and antihypertensive combination is Angiotensin Receptor Blocker (ARB) - Calsium Chanel Blocker (CCB) of 65.95%. Based on the results of analysis, the results obtained for the right drug and the patient is 98.86% and for the accuracy of the dose obtained 97.72%.
Pattern of Antibiotic in Community-Acquired Pneumonia (CAP) Comparison in Type A and B Hospital Ika Puspita Sari; Titik Nuryastuti; Rizka Humardewayanti Asdie; Anton Pratama; Endang Estriningsih
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33261

Abstract

Pneumonia is a threat to all States. CAP treatment in hospitals typically uses empirical antibiotic therapy with IDSA/ATS guidelines. This research aimed to compare empirical antibiotic therapy of CAP patients in types A and B hospital and to analyze the variations that occur and compare the outcome of the therapy. The research was conducted retrospectively by collecting data from the medical records of patients diagnosed with CAP. The inclusion criteria in this research were male and female adult patients aged ≥18 years who had complete medical record data. Patients who underwent inpatient care in the in-patient wards (non ICU) of type A and B hospital received empirical antibiotic therapy. Data from type A hospital (RS A) were taken within the period of January 2014-December 2016, while data from type B hospital (RS B) were taken in January 2013-December 2016. The number of patients with CAP in hospital A is 72, whereas in hospital B, it is 34. Patients with malignancy and immunocompromise were excluded from this research. In this research, germs found in hospital A were mapped, while no gynecologic examination/culture was performed in hospital B. The outcome of the treatment was an improvement in response 5-7 days after empirical antibiotics was given, as reported by a physician and/or by an improvement in the x-ray thorax results. Patient demographic data and antibiotic therapy pattern were analyzed descriptively. Outcome of patient therapy was analyzed using Chi square statistics with 95% confidence level.The results showed that empirical antibiotic therapy in CAP patients in type A hospital were largely based on IDSA/ATS guidelines, whereas in it is the opposite for type B hospital. Outcomes of patient therapy in A and B hospitals showed patient improvement of about 76%. In type A hospital, the cause of CAP is largely negativeGram bacteria which are still sensitive to cephalosporin/carbapenem (cefpirom, ceftasidim, cefepim, and imipenem) and aminogicosida (amikacin, netilmisin, and tobramisin).
Validity and Reliability Test of Indonesian Version B-IPQ to CRF Outpatients in RSUD Soedarso Pontianak Nurul Hadisa; Ressi Susanti; Robiyanto Robiyanto
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33340

Abstract

Brief Illness Perception Questionnaire (B-IPQ) Instrument is a questionnaire to identify and assess the patient's perception of the disease, especially patients with chronic diseases. Chronic renal failure (CRF) is one of incurable diseases with the expensive cost of care and treatment. B-IPQ instrument has never been used yet in Indonesia to assess patients’ perceptions of chronic renal failure which have experience haemodialysis especially in Pontianak, West Kalimantan. The aim of this study was to determine the validity and reliability of B-IPQ instrument in Indonesian version on CRF patients at haemodialysis room RSUD Dokter Soedarso Pontianak. This study was a non-experimental study using cross-sectional method and prospective data collection. The sample is selected using non-probability sampling method rather purposive sampling technique, 30 CRF patients who had haemodialysis in November-December 2016 were taken as respondent. The validity test was conducted using Pearson correlation (correlation values ≥0.3) and reliability test using internal consistency (Cronbach alpha coefficient ≥0.7) technique. Validity test results showed a correlation value of each question was >0.3 (p: 0.05) and reliability test results showed Cronbach alpha coefficient was 0.755>0.7 (p: 0.05). The conclusion of this study was the B-IPQ instrument in Indonesian version is valid and reliable to measure the chronic renal failure patients’perception at haemodialysis room RSUD Dokter Soedarso Pontianak. Hence B-IPQ Indonesian version can be used directly to measure the perception of the disease in patients with CRF in order to help improve the quality of life of patients.
Correspondence Analysis between Me Too Drugs Formulation with Patent Information and the Analytical Method (Case Study: Amlodipine Tablets - PT Indofarma (PERSERO) Tbk.) Fetrikani Andartaji; Gede Bayu Suparta; Marchaban Marchaban
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.33260

Abstract

One of the blockbuster drugs that has been off-patent and attract domestic pharmaceutical industry to produce a lot of version of me too is anti-hypertensive drugs Norvask®, in which the active ingredient is the salt form of amlodipine besylate. The goal of this study is to verify the conformity between me too drugs formulation and patent information (Case study: Amlodipine Tablets – PT Indofarma (Persero) Tbk). The results are expected to change the views of people who often doubt that me too drugs quality are smaller than patent drugs. The analysis method used in this study is performed descriptively. Information about amlodipine formulation obtained from PT Indofarma (Persero) Tbk is verified with the active substance test results obtained from amlodipine drugs on the market. After that, the total results can be compared with the proprietary patent information obtained from United States Patent and Trademark Office (USPTO) website. The result showed that there is a compatibilty between formulation of me too drugs and patent information (Case Study: Amlodipine – PT Indofarma (Persero) Tbk) in major issues such as compotition, active ingredient, level of active ingredient, dosage form and production process. Profile dissolution which is owned by amlodipine tablet from PT Indofarma (Persero) Tbk remains equivalent to the innovator product (Norvask®), although there was a modification by adding an excipient X. Amlodipine tablet generic produced by PT Indofarma (Persero) Tbk is me too 100% (identical).

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