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Farmasains : Jurnal Ilmiah Ilmu Kefarmasian

farmasains
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Published by Universitas Muhammadiyah Prof. Dr. Hamka

ISSN : 20866968 EISSN : 26219816 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is an national journal published by Faculty of Pharmacy and Science University of Muhammadiyah Prof. DR. HAMKA. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is aimed at being a medium for research results dissemination and scientific paper exchanges on the pharmaceutical field among academics, practitioners, regulators, and public. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is issued two times annually, i.e., in April, and October.The Editor receives rigorous research manuscripts that have not been offered for publication elsewhere. Since its first issue published in 2010. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian has become a CrossRef Member since 2019. Therefore, all articles published by Farmasains: Jurnal Ilmiah Ilmu Kefarmasian will have unique DOI number with p-ISSN 2086-6968 dan e-ISSN 2621-9816

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Articles 5 Documents

Search results for , issue "Vol. 3 No. 2 (2016)" : 5 Documents clear

VARIASI KONSENTRASI ASAM SITRAT SEBAGAI SUMBER ASAM TERHADAP SIFAT FISIK TABLET EFFERVESCENT EKSTRAK KERING KULIT BUAH MANGGIS (Garcinia mangostana L) inding gusmayadi; pramulani mulya lestari; erike trisnande
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 2 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Citric acid is an acid source in effervescent tablet it reacts rapidly, can increase dissolving time. In this research, extract was made into effervescent tablet. The research aimed at knowing increased concentration of citric acid as acid source can improve the physical characteristic of effervescent tablet. Pericarp mangosteen dry extracts macerated by water, and powder made by spray dryer. Dry extract was made into 5 formulas effervescent tablet with the different concentrations of citric acid, 15%, 20%, 25%, 30% and 35% as acid sources. The tablets were evaluated included organoleptic evaluation, weight uniformity, size uniformity, hardness, friability, and dissolving times. The result of dissolving time are 10,50±0,57 minutes, 4,52±1,04 minutes, 3,32±0,13 minutes, 3,13±0,14 minutes and 3,42±0,14 minutes. By one way ANOVA test dissolving time data showed differences each other 95% in signifigancies. It can be concluded that increasing of citric acid gave effect on dissolving time, and the citric acid with concentration of 35% can reduce dissolving time of the pericarp mangosteen (Garcinia mangostana L.) dry extract effervescent tablets.

IDENTIFIKASI INTERAKSI OBAT-OBAT POTENSIAL PADA PASIEN GAGAL GINJAL KRONIK RSPAD GATOT SOEBROTO maifitrianti maifitrianti
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 2 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Drug interactions are directly related to factors such as polypharmacy, aging, hepatic metabolism and decreased renal function. Polypharmacy is common in drug prescriptions of chronic kidney disease patients. A study of the prescription patterns of drugs with potential interactions would be of interest to prevent drug related adverse events. The aim of this study was to identify potential drug-drug interactions among chronic kidney disease among hospitalized patients in Gatot Soebroto Army Hospital, Jakarta period October to December 2015 This study was an observational research with descriptive approach. Data were obtained retrospectively. Data was collected from patient’s medical record. The sampels were hospitalized patients with chronic kidney disease in Gatot Soebroto Army Hospital, Jakarta period October to December 2015 that received at least two drugs in one prescribing pattern. The samples which fulfilled the inclusion criteria were 63 patients and found as many as 443 potential drug interactions. Drug interactions with pharmacodynamic mechanism were 235 cases (53.04%) and pharmacokinetics as much as 208 cases (46.96%). A total of 334 cases (75.39%) were drug interactions with moderate severity. drug interactions are commonly seen in the prescriptions of chronic kidney disease patients which can lead to serious adverse events if not detected early.

PENGARUH PENINGKATAN KONSENTRASI PEKTIN SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK MARSHMALLOW ANTISARIAWAN EKSTRAK KENTAL DAUN SAGA (Abrus precatorius L.) rahmah elfiyani; ari widayanti; budiarti rahayu
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 2 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Saga leaves (Abrus precatorius L.) have anti-thrush activity and contain glisirizin. Glisirizin is a compound of saponin glycosides non hemolytic, class of triterpenoid and have anti-parasitic activity. This study aims at knowing effect of increasing concentration of pectin as gelling agent on physical properties marshmallow. Saga leaves extract made in to marshmallow 4 formulas, with variations of concentrations of pectin 0.7%, 0.8%, 0.9% and 1%. The physical properties evaluations included organoleptic, uniformity of weight, uniformity of size, moisture content, and texture. The hardness test result data obtained in 859.33; 710.03; 677.13; 506.36 gf, the cohesiveness test result data 0.7375; 0.8247; 0.8780; 0.9327 gs, the springiness test result data 0.7255; 0.8142; 0.8530; 1.0236 gs. Data were analysed using one-way ANOVA followed by Tukey test. The result showed that the higher concentration of pectin will increase springiness and cohesiveness and reduce hardness of marshmallow of viscous saga leaves extract.

UJI EFEK ANTIGLAUKOMA INFUS DAUN KITOLOD (Isotoma longiflora (L) C.Presl) TERHADAP TIKUS PUTIH JANTAN BERDASARKAN TEKANAN BOLA MATA siska siska; hadi sunaryo; teja kusuma wardani
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 2 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Glaucoma is abnormality in the eyes of the increasing pressure (intraocular) that able to push optic nerve so that can cause nerve optic damage in the eyes. The damage to the optic nerve can cause visual field reduction, so that can cause blindness. Increased intraocular pressure caused by inhibition of aqueous humeous. The mechanism of medication for glaucoma is to reduce intraocular pressure. Kitolod leaves (Isotoma longiflora (L) C.Presl.) One of the many wild plants used to treat eyes diseases in traditional societies, one to treat glaucoma, therefore to prove activities as antiglaucoma then do research in order to determine the effect infuse of kitolod leaf to the intraocular pressure. This research uses 5 groups negative, positive, concentration 40%, concentration 50%, concentration 60%. This research use the inducer prednisolone acetate eye drops 1% and the positive comparator is pilocarpine 2% eye drops. Measurement of eyes pressure use the tonometer Schiotz The results of the research showed that concentration 60% has effects of lowering the eye pressure is comparable with pilocarpine 2% eye drop.

PENGARUH EDUKASI DAN HOMECARE OLEH FARMASIS TERHADAP PENGETAHUAN DAN KEPATUHAN PASIEN DIABETES MELITUS TIPE 2 vony nofrika; syamsuddin syamsuddin; Sesilia A Keban
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 3 No. 2 (2016)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Increased knowledge and compliance of type 2 DM patient should be supported by the pharmaceutical services in the form of education and homecare. The purpose of this research to determine the effect of the implementation of pharmacists services in improving the knowledge and compliance of type 2 DM patient so that blood sugar levels can be controlled properly. this research is a prospective, quasi-experimental methods nonequivalent control group design. Respondents were 108 people divided into 3 groups of intervention namely the control group, the intervention group I conducted Education twice by using booklet media, and the second intervention group was educated and homecare pharmacist respectively twice. The results showed that the average value of knowledge and compliance in the intervention group I showed an increase from 68.81 to 70.06 and 2.01 to 0.38. While in the intervention group II there was an increase from 66 to 72,34 and 3,97 to 0,14. GDPP levels before the intervention included poorly controlled categories turned to moderate control after intervention II.

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