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INDONESIA
Indonesian Journal of Rheumatology
Published by Indonesian Rheumatology Association
ISSN : 20861435     EISSN : 25811142     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific and medical practice in rheumatic diseases and connective tissue disorders. This journal is self-focused on rheumatic disease and connective tissue disorders in the form of original article (extended and/or concise reports), review articles, editorial letters, leaders, lesson from memorable cases, book reviews, and matter arising. Both in clinical and laboratory including animal studies.
Arjuna Subject : -
Articles 252 Documents
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Quantitative Evaluation of Proteinuria with Urinalysis Test and Comparing Its Correlation with Random Spot Urine PCR and 24-Hour Urine Protein in SLE Patients: Analysis of proteinuria Chun Ruh Ng; Yet Lin Loh; Dawan Khadijah
Indonesian Journal of Rheumatology Vol. 14 No. 2 (2022): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v14i2.214

Abstract

Introduction: Lupus nephritis is an important concern among systemic lupus erythematosus (SLE) patients in Asia, and its mortality rate was reported to be 6 times higher compared to the general population. 24-hour urine protein collection has long been used as the gold standard test to assess proteinuria. This study aimed to assess the correlation of urinalysis test with random spot urine protein-creatinine ratio (PCR) compared with 24- hour urine protein. Methods: This was a retrospective study. The electronic medical records of all SLE patients seen in the rheumatology clinic of Hospital Sultan Ismail from 1st January 2017 to 1st January 2021 were reviewed. Patients who had urinalysis, urine protein-creatinine ratio, and 24-hour urine protein tests were identified. Data on demography, urinalysis, random spot urine protein-creatinine ratio, and 24-hour urine protein were obtained and analysed. Results: The correlation between urinalysis and 24-hour urine protein was strong (r=0.702), whereas the correlation between urinalysis and urine PCR was stronger (r=0.797). Our study also showed the correlation between random urine protein-creatinine ratio and 24-hour urine protein is strong (r=0.782). Conclusion: Urinalysis correlates well with both random spot urine protein-creatinine ratio and 24-hour urine protein, and the correlation is stronger with urine protein-creatinine ratio.
Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Glucocorticoid-induced Osteoporosis Bagus Putu Putra Suryana; Rudy Hidayat; Laniyati Hamijoyo; Radiyati Umi Partan; Yulyani Werdiningsih; Surya Darma; RM Suryo Anggoro; Anna Ariane; Faisal Parlindungan; Mirza Zaka Pratama; Harry Isbagio; Handono Halim; Cesarius Singgih Wahono; Sumariyono
Indonesian Journal of Rheumatology Vol. 14 No. 2 (2022): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v14i2.216

Abstract

Background: Patients receiving long-term glucocorticoid therapy are at risk of developing GIOP. However, until today, there is still no guideline that specifically explains how to diagnose and manage GIOP patients in Indonesia. Methods: 10 selected rheumatologists from the Indonesian Rheumatologist Association (IRA) made recommendations based on key questions formed by a steering committee from IRA. These recommendation materials were taken from several online databases such as Pubmed, Science Direct, and Cochrane. Level of evidence and grades of recommendation were then assigned, and every member of the panelist team will assign a score for the level of agreement. Results: A total of 17 recommendations regarding screening, prevention, diagnosis, therapy, and monitoring for GIOP were made. Conclusion: These recommendations can be used for adult patients receiving long-term glucocorticoids with or at risk of developing GIOP. The prevention measure, diagnostic, therapy, and monitoring algorithm in this recommendation are all created with the consideration of Indonesia’s clinical setting, facility, and drug availability.
Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Osteoarthritis (Knee, Hand, Hip) Rakhma Yanti Helmi; Najirman; Ida Ayu Ratih Wulansari Manuaba; Andri Reza Rahmadi; Pande Ketut Kurniari; Malikul Chair; Ika Vemilia Warlisti; Eka Kurniawan; Harry Isbagio; Handono Kalim; Rudy Hidayat; Laniyati Hamijoyo; Cesarius Singgih Wahono; Sumariyono
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.225

Abstract

Background: Osteoarthritis (OA) is the most common form arthritis in the world, and its prevalence is predicted to rise higher in the future due to increasing life expectancy and growing number of elderly population. With the emergence of new treatment options in the last several years, a better understanding of OA diagnosis and management is required by every physician in Indonesia. Methods: A panel of eight selected rheumatologists from the Indonesian Rheumatologist Association (IRA) developed recommendations based on key questions formulated by a steering committee from IRA. These recommendation materials were taken from several online databases such as PubMed, Science Direct, and Google Scholar. Level of evidence and grades of recommendation were then assigned, and each member of the panelist team will assign a score to express their level of agreement. Results: A total of 25 recommendations discussing the diagnosis, pharmacological and non-pharmacological therapies, as well as monitoring for OA were formulated. Conclusion: These recommendations can be used to help clinicians in accurately diagnosing OA and choosing the most suitable therapy for their patients. All recommendation statements were tailored to the clinical setting, facility, and drug availability in Indonesia.
The Role of Antioxidants as Adjuvants of Fibromyalgia Management Sabrina Chusnul Chotimah; Hamzah Shatri; Rudi Putranto; Edward Faisal; Vinandia Irvianita; Yanuar Ardhani; Dika Sinulingga
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.233

Abstract

Fibromyalgia is a condition with complex polysymptomatology characterized by chronic widespread pain, fatigue, sleep disturbances, and functional symptoms. Oxidative stress plays a role in the etiology of pain which is the main symptom of fibromyalgia. The symptoms of fibromyalgia are related to the balance of oxidant and antioxidant. Antioxidants from certain nutrients can act to counter the high level of free radicals, in order to maintain the oxidative stress/antioxidant balance. Antioxidant such as coenzyme Q10, vitamin C and E, magnesium, and acetyl-L-carnitine have the potential benefit as adjuvants in treating fibromyalgia by reducing pain.
Tuberculosis Arthritis: A Diagnostic Challenges Desak Putu Gayatri Saraswati Seputra; Pande Ketut Kurniari
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.237

Abstract

Background: Tuberculosis infection still poses a significant health problem, especially in developing countries. While most of tuberculosis cases affect the pulmonary organ, this infection may also involve other organs such as bones and joints. Case presentation: We reported a case of 23-year-old female patient with a history of recurrent pain and swelling in the right knee. On physical examination of the right knee, bulging sign was found, accompanied by tenderness, warmth on palpation, and limited active and passive movement. Radiographic examination was suggestive for septic arthritis in the right knee. Debridement and biopsy were performed, and TB PCR examination of the debridement tissue was found to be positive for Mycobacterium tuberculosis. The histopathological finding was also consistent with tuberculosis infection. The patient was subsequently treated with antituberculosis drugs and underwent rehabilitation therapy, resulting in a satisfying response. Conclusion: Diagnosis of tuberculosis arthritis in this case was established based on the presence of clinical symptoms, radiological findings, tissue TB PCR, and histopathological findings. Both surgical and pharmacological interventions were performed, which yielded favorable results. Tuberculosis arthritis was often misdiagnosed as arthritis for other causes, resulting in delays in providing medical intervention. Therefore, increased understanding of tuberculosis arthritis is necessary to facilitate early diagnosis and improve therapeutic outcome.
A Patient with Granulomatosus with Polyangiitis (Wegener’s Granulomatosis): A Case Report: A Case Report Harris Hardian; Pande Ketut Kurniari; Gede Kambayana
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.240

Abstract

Background: Granulomatosus with Polyangiitis (GPA) is an Anti-neutrophilic Cytoplasmic Antibodies (ANCA) Associated Vasculitis (AAV) which involves small to moderate-sized vessels. GPA has a variety of clinical manifestations caused by tissue ischemia and organ affected. Diagnosis of GPA remains challenging, and its actual incidence may be higher than reported. In 1990, the American College of Rheumatology (ACR) published diagnostic criteria for GPA. Guidelines of management of GPA has improved survival in last decade, but results remain unsatisfactory. Induction agents with immunosuppressive agents and glucocorticoid, and the newer agent Rituximab are recommended as first choice treatment. Case presentation: A 64-year-old male presented with current episode of joint pain and a history of recurrent respiratory tract infections. After a series of laboratory and radiologic examinations, lung biopsy was performed, and the result was suggestive of GPA. The patient was managed with induction remission agent and reported improvement in both clinical and laboratory parameters. Conclusion: Granulomatosus with Polyangiitis is a limitedly reported case. This report was presented to raise awareness of the diagnosis when faced with similar clinical symptoms. Early detection and diagnosis in GPA allow for prompt and better management with the target to achieve and maintain remission, as demonstrated in this case.
Efficacy and Safety of Stem Cell Transplantation in Rheumatoid Arthritis: A Systematic Review of Trials Eric Ferdinand; Grady Krisandi; Phoniex Angellia
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.241

Abstract

Background: Rheumatoid arthritis (RA) is an autoimmune disorder that deteriorates the quality and function of the synovium membrane, resulting in chronic inflammation, pain, and progressive joint destruction. Based on previous clinical research, stem cell transplantation has shown a promising therapeutic effect for RA based on its anti-inflammatory, immunomodulatory, and regenerative properties. This systematic review aims to evaluate the efficacy and safety of stem cell transplantation for rheumatoid arthritis therapy. Methods: A literature search was performed via PubMed, ProQuest, EBSCOHost, EMBASE, SCOPUS, Cochrane, DOAJ, and clinicaltrial.gov databases, selecting studies that evaluated the effect of stem cells on rheumatoid arthritis from inception to April 7, 2023. The Cochrane Risk of Bias was used to assess randomized controlled trials and ROBINS-I was used to assess clinical trials. Results: 7 randomized controlled trials (RCTs) and 12 non-randomized studies involving 682 subjects were included in this review. Stem cell transplantation was related with better outcomes based on significant improvement of the DAS28 score, HAQ score, ACR score, and laboratory parameters. There were no significant changes in safety parameters compared to the baseline value and control group. Fever, flu-like symptoms, nausea, and vomiting were the most frequently reported adverse effects. Nevertheless, this review revealed a moderate risk of bias and high heterogeneity of the efficacy outcomes of RCTs. Conclusion: Stem cell-based therapies provide clinical benefits for rheumatoid arthritis patients with satisfactory safety measures.
Simultaneous Cervical and Lumbar Spinal Degenerative Stenosis: Diagnostic and Treatment Challenge Wendlassida Joelle Stéphanie TIENDREBEOGO/ZABSONRE; Denlewende Sylvain ZABSONRE; Abdoulaye SANOU; Amitandi Armand 1er Jumeau OGOABIGA; Yakouba HARO; Inoussa ZOUNGRANA; Fulgence KABORE; Dieu-Donné OUEDRAOGO
Indonesian Journal of Rheumatology Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v15i1.243

Abstract

Background: In simultaneous cervical and lumbar degenerative stenosis (tandem spinal stenosis), the cervical clinical signs may mask the lumbar ones. Treatment is initially conservative in non-plegic cases. In the event of surgery, there is no consensus regarding the segment to be approached first. The purpose of this work was to describe our management of this condition. Methods: This was a 6-year retrospective study in the rheumatology and neurosurgery departments. All usable medical records of cases of simultaneous degenerative stenosis of the cervical and lumbar spine were included. Results: We retained 84 squares. The average age was 57.1 years; the sex ratio 0.9. All the patients presented cervical and lumbar clinical signs. They had started at the lumbar spine in 46 cases (54.8%) and cervical in 38 cases (45.2%). A full spinal MRI had been performed in 50%. Conservative treatment was effective in 36 patients (42.9%). Of the 32 patients (66.7%) operated, 16 had been operated both the cervical and lumbar spine (7 simultaneous surgeries including percutaneous discolysis in one of the segments in 4 cases). The cervical spine had been operated on first in 7 of the 9 cases of staggered surgery. After an average follow-up of one month, the evolution was favorable in 47 cases (56%); stationary 21 (25%). Conclusion: Conservative treatment was effective in about half of the cases. Full spine MRI and staggered surgery were the most commonly performed. However, simultaneous surgery prioritizing the least aggressive gestures seems better.
Correlation between Uric Acid Levels and the Severity of Psoriasis Vulgaris Patients Pristia Widya Monica; Nurrachmat Mulianto
Indonesian Journal of Rheumatology Vol. 13 No. 3: Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i3.248

Abstract

Introduction: Psoriasis vulgaris (PV) is a recurrent chronic inflammatory skin disease characterized by erythematous, scaly, well-defined plaques with the greatest predilection, generally in the areas of the elbows, knees, scalp, and lower back. The psoriasis area and severity index (PASI) is one of the most widely used evaluation tools to determine the development of psoriasis vulgaris in a patient. Hyperuricemia is the dominant risk factor for PV when compared to other known risk factors, such as obesity or metabolic syndrome. This study aimed to determine whether there is a relationship between serum uric acid levels and the severity of PV based on the PASI score. Methods: Cross-sectional study with one-time sampling conducted from December 2021 to February 2022 in psoriasis vulgaris patients who came to the Dermatology and Venereology clinic at Dr. Moewardi General Hospital, Surakarta, Indonesia. All data were statistically analyzed using SPSS 26. Variables, including age, gender, disease duration, body mass index, and uric acid levels, were subjected to univariate analysis. Bivariate analysis was then followed by a parametric test. The p-value <0.05 was considered significant. Results: There were 36 patients during the study period. The average uric acid level was 6.0135, with an average PASI score of 10.6388. The relationship between uric acid levels and the severity of psoriasis vulgaris was found to be significant, with a value of p = 0.025. Conclusion: There is a significant relationship between uric acid levels and the severity of psoriasis vulgaris, where the higher the uric acid level, the more severe the severity of psoriasis vulgaris.
Post Operative Management in Intensive Care of Obstructive Jaundice caused by Choledocholithiasis: A Case Report Liliriawati Ananta Kahar; Wiwi Monika Sari
Indonesian Journal of Rheumatology Vol. 13 No. 3: Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i3.257

Abstract

Introduction: Gallstones are a very common problem in the global population. 10%-25% of affected people may have specific symptoms, and 1%-2% of them may experience major complications. Case presentation: 83-year-old female patient complained of yellow in her eyes and skin. Patients also felt pain in the right upper abdomen. Laboratory examination revealed increased bilirubin serum. Abdominal Ultrasound examination showed Obstruction of the Bilier Ductus caused by a stone at ductus sisticus and sludge of the gallbladder. The patient was diagnosed with Jaundice obstruction caused by obstruction of the bile ducts due to a stone at the ductus sisticus with a history of nephrectomy, Hypertension, and type 2 diabetes. The patient underwent Laparoscopic cholecystectomy, ERCP, and stent biller, After the procedure, the patient was admitted to the intensive care unit. Conclusion: Understanding the patient's comprehensive medical and surgical history is fundamental in understanding the postoperative patient in the intensive care unit. Adequate resuscitation is necessary for good clinical perfusion and physiological stability of the patient.

Page 25 of 26 | Total Record : 252

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