cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
Indonesian Journal of Rheumatology
Published by Indonesian Rheumatology Association
ISSN : 20861435     EISSN : 25811142     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Rheumatology is a peer-reviewed open access journal on rheumatic diseases and connective tissue disorders. This is an official journal of Indonesian Rheumatology Associantion (IRA) and published twice a year since 2009. Our mission is to encourage the development of scientific and medical practice in rheumatic diseases and connective tissue disorders. This journal is self-focused on rheumatic disease and connective tissue disorders in the form of original article (extended and/or concise reports), review articles, editorial letters, leaders, lesson from memorable cases, book reviews, and matter arising. Both in clinical and laboratory including animal studies.
Arjuna Subject : -
Articles 252 Documents
 21   22   23   24   25 
Idiopathic CD4+ Lymphocytopenia in Overlap Syndrome (Systemic Sclerosis with Dermatopolimyositis) Sumartini Dewi; Tasya Aniza Yusuf; Fahrizal Yanuar
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.165

Abstract

Background : Idiopathic CD4 T cell lymphocytopenia (ICL) is a rare syndrome with varied clinical manifestation, characterized with lymphopenia and decreased in CD4 level without HIV infection or other possible cause of immunodeficiency state. Autoimmune diseases might be a clinical manifestation of ICL. However, it is not known whether ICL triggered an autoimmune diseases, or it is a complication of said diseases. Objective : Awareness of ICL in patient with known autoimmune diseases whom admitted to the hospital for severe infection. Methods : This case report showed a 24-years old woman with prolonged fever since 4 moths ago. It was accompanied with oral ulcers, skin rash in face and trunks, and weakness of lower extremities. She was diagnosed with systemic sclerosis since 2016 and routinely came to rheumatology outpatient clinic in Hasan Sadikin Hospital but stopped coming for past 4 months since pandemic. Her current medication was only 4 mg of methylprednisolone. Results : She had high temperature (38.5 degree Celsius) and tachycardia. Physical examination revealed a single lymphadenopathy at neck. Raynaud phenomenon, calcinosis, and sclerodactyly was found in lower extremities. Dermatomyositis was diagnosed based by heliotropic skin rash. Laboratory tests showed leukopenia, absolute lymphocyte count 135.2 cell/mm3, absolute CD4 39/uL, CK level of 3296 and nonreactive anti-HIV. The patient underwent empirical antibiotic treatment, but unfortunately passed away. Conclusion : ICL is a rare case, following an infection, autoimmune diseases, or unspecified malignancy. Clinician’s awareness toward ICL could prevent fatal opportunistic infection which often happens to patients with immunodeficiency state.
Should Patient with Autoimmune Inflammatory Rheumatic Diseases (AIIRD) be vaccinated with COVID-19 Vaccines? Cesarius Singgih Wahono; Perdana Aditya; Faisal Parlindungan; RM. Suryo Anggoro KW; Anna Ariane; Herlina Yani; Andi Raga Ginting; Lisa Kurnia Sari; Pande Ketut Kurniari; Ratih Manuaba; Ika Vemilia; Rudy Hidayat; Sumariyono Sarmidi; Harry Isbagjo
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.167

Abstract

Vaccination is a very important measure for the prevention of various infections worldwide including the recent COVID-19 disease. However, until now the COVID-19 vaccine with various platforms has not been clinically tested on autoimmune inflammatory rheumatic disease (AIIRD) patients, due to caution against possible side effects and unknown efficacy. Several recent studies proved that there is increased risk of SARS-CoV-2 infection in AIIRD patients and moreover, those patients also have worse COVID-19 outcomes. Thus, patients with AIIRD should be prioritized for vaccination because they have an increased burden of infections, including COVID-19. Many studies showed that inactivated/non-live vaccine is safe for AIIRD patients and do not cause disease exacerbations. We conclude that benefits of vaccination greatly outweigh the risks of infection and therefore, COVID-19 vaccines can also be administered safely in stable AIIRD patients.
Effect of Vitamin D Supplementation in Disease Activity, Activity-Related Markers, Inflammatory Marker and Serum Calcium of Systemic Lupus Erythematosus Patiens: A Systematic Review and Meta-Analysis G Kambayana; Dwijo Anargha Sindhughosa; Pande Ketut Kurniari; Wira Gotera; Yenny Kandarini
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.168

Abstract

Background: Effect of additional supplementation of vitamin D toward Systemic lupus erythematosus (SLE) disease activity still differ in results obtained between studies being conducted. The current meta-analysis systematically analyzed the effect of vitamin D supplementation on SLE disease activity with updated literature, also its effect toward other parameters. Material and Methods: Relevant literatures were obtained from PubMed database and Google Scholar. The obtained studies were analyzed using fixed effect model or random effect model. Results: Five eligible studies with a total of 318 participants were included. Vitamin D supplementation did not affect the total SLEDAI score in SLE patients with pooled mean difference of -0.96 (p =0.09; 95% CI: -2.06 to 0.14). Serum vitamin D level increased after administration of vitamin D with pooled mean difference of 12.67 (p =0.001; 95% CI: 5.04 to 20.29). vitamin D supplementation increase serum calcium levels, with pooled difference of 0.07 (p = 0.006; 95% CI: 0.02 to 0.12). Pooled results from two studies obtained vitamin D supplementation did not affect ESR, C3 and C4. Conclusions: Current meta-analysis obtained no significant changes in SLEDAI scores due to vitamin D supplementation. In contrast, serum vitamin D and serum calcium levels were increased.
Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Rheumatoid Arthritis Rudy Hidayat; Bagus Putu Putra Suryana; Linda Kurniaty Wijaya; Anna Ariane; Rakhma Yanti Hellmi; Endy Adnan; Sumariyono
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.173

Abstract

Introduction: Rheumatoid arthritis (RA) is an autoimmune rheumatic disease which often found in daily practice and requires certain considerations in recognizing clinical appearance also managing the disease as it often causes permanent joint damage, disability, even premature death. This recommendation is expected to become the latest reference for diagnosis and management of RA in Indonesia. Methods: The steering committee was formed by the Indonesian Rheumatology Association (IRA) to formulate key questions; conduct literature search, selection, and review; then formulate recommendation statements for diagnosis, therapy, and monitoring of RA. Furthermore, the steering committee determined the level of evidence and grades of the recommendations. After that, the level of agreement (LOA) was determined for each item by panelists including rheumatology consultants who have been appointed by IRA to represent Indonesia regions. Results: The steering committee established 30 recommendations including diagnosis, the role of laboratory and radiology tests, general treatment, the use of glucocorticoids, sDMARD, bDMARD, and tsDMARD. This recommendation also discusses guidelines on monotherapy, combination therapy, treatment strategies (treat-to-target), tapering, and continuous clinical remission. Treatment on co-morbidities and complications are also included in brief. Conclusion: IRA recommendations regarding the diagnosis and management of RA was made by considering various aspects such as the availability of drugs and supporting facilities, socioeconomic and cultural conditions in Indonesia, as well as the latest research that can be applied to Indonesian population.
Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Axial Spondyloarthritis 2021 Ayu Paramaiswari; R.M. Suryo Anggoro Kusumo Wibowo; Yulyani Werdiningsih; Arief Nurudhin; Surya Darma; Lita Diah Rahmawati; Sumartini Dewi; Rudy Hidayat; Sumariyono
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.174

Abstract

Objective. Recommendations for spondyloarthritis are made to provide guidelines in diagnosis establishment, therapy, and monitoring of axial spondyloarthritis cases.Method. Literature searches were conducted online. The drafting team determines the levels of evidence (LOE) and grades of recommendation (GOR). After conducting a discussion, each recommendation that has been agreed upon by the drafting team is then classified based on the levels of evidence and grades of recommendation. The final step in the preparation of these recommendations is to determine the level of agreement (LOA) on each recommendation carried out by a team of panelists who have been appointed by IRA.Results. Twenty recommendations regarding axial spondyloarthritis were established. Strong recommendations or GOR A include: Ax-SpA diagnosis can be made according to the 2010 ASAS criteria, or the 1984 modified New York criteria specifically for the US; conventional radiographic examinations and MRI of the sacroiliac joints and vertebrae may be used as evaluators of disease activity and predictors of therapeutic response, as well as patients who do not respond to NSAIDs (within 4 weeks) can be administered a combination of NSAIDs and anti-TNF, and if it is not possible, a combination of NSAIDs and anti-IL-17A (Secukinumab, Ixekizumab).Conclusion. These recommendations provide a direction for clinicians to diagnose and manage spondyloarthritis.
Indonesian Rheumatologist Association (IRA) Recommendations for Diagnosis and Management of Peripheral Spondyloarthritis 2021 Sumartini Dewi; Arief Nurudhin; Ayu Paramaiswari; R.M. Suryo Anggoro Kusumo Wibowo; Yulyani Werdiningsih; Surya Darma; Lita Diah Rahmawati; Rudy Hidayat; Sumariyono
Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i1.175

Abstract

Objective. Spondyloarthritis recommendations are made to provide guidance in diagnosis, treatment, and monitoring of peripheral spondyloarthritis cases.Method. Literature searches were conducted online. The drafting team determines the levels of evidence (LOE) and grades of recommendation (GOR). After conducting a discussion, each recommendation that has been agreed upon by the drafting team is then classified based on the levels of evidence and grades of recommendation. The final step in the preparation of these recommendations is to determine the level of agreement (LOA) on each recommendation carried out by a team of panelists who have been appointed by IRA.Result. Thirty five recommendations regarding peripheral spondyloarthritis were compiled. There are 6 strong recommendation or GOR A for psoriatic arthritis and 8 recommendations for enteropathic arthritis.Conclusion. These recommendations provide directions for clinicians to diagnose and to manage peripheral spondyloarthritis.
Avascular Osteonecrosis in Systemic Sclerosis Patient: Risk Factors and Role of Vasculopathy? Safarina Kharima Laitupa; Perdana Aditya Rahman
Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i2.162

Abstract

Avascular Necrosis (AVN) or osteonecrosis refers to the death of osteocytes and osteoblasts. Sites such as the femoral head, the head of the humerus and the mandibular with restricted access to local blood supply are particularly vulnerable to osteonecrosis. Various traumatic and non-traumatic causes of AVN are known, including systemic autoimmune diseases. Among traumatic causes, physical trauma, decompression sickness or radiation may be cited. In the non-trauma cases, two theories are disputed: the first concerns the occurrence of an intravascular coagulation and the second one attributes the ischemia to extravascular compression. AVN has been well described in patients with autoimmune diseases such as systemic lupus erythematosus, but in systemic sclerosis (SSc) patients, there have been limited case reports and case series. We present a case of a 32-year old woman with systemic sclerosis on corticosteroid and avascular osteonecrosis and elaborating possible etiologies or mechanism of avascular osteonecrosis in SSc.
Difference between the Decrease in P1NP Concentration and MRSS Within 3 Months Treatment of Systemic Sclerosis Devy Priyantini Hanafi; Sumartini Dewi; Andri Reza Rahmadi
Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i2.184

Abstract

Introduction: Systemic sclerosis is characterized by extensive and progressive organ fibrosis leads to organ failure and death. Progression of skin thickening is a predictor of morbidity and mortality. Due to the limitation of modified Rodnan skin score (MRSS) sensitivity in detecting small changes in skin fibrosis, thus we proposed Procollagen Type I N-Terminal Propeptide (P1NP) as potential biomarker. This study aimed to analyze the difference between the decrease in P1NP concentration and MRSS within 3 months treatment of systemic sclerosis. Methods: We conducted a retrospective cohort of paired numerical comparative analytic methods, as follow up of a study done by Vincent et al. and Dewi et al. Analyzis of MRSS changes and serum P1NP concentrations were done prior to treatment (baseline), and on week 4th, 8th and 12th treatment. Result: Fifty-nine subjects were enrolled in the study. We analyzed the results of P1NP and MRSS at 4th, 8th and 12th weeks of treatment, there was a significant decrease in mean rank of P1NP and MRSS (p=0.033 and <0.001). The effect of MRSS change was greater than P1NP. The highest decreasing effect of MRSS was obtained at week 8th (?2 = 0.424, 42.4% decrease effect), and the largest decrease effect of P1NP was obtained at week 12th (?2 = 0.120; 12% decrease effect). Conclusion: There was a difference in decreasing P1NP concentrations and MRSS in systemic sclerosis within 3 months of observation. MRSS showed a larger decrease in change than P1NP after treatment.
Is There Any Correlation between Anti-Ro 52 Antibody Level with Hematological Abnormalities in Systemic Lupus Erythematosus? Andiyang R. Diredja; Amaylia Oehadian; Laniyati Hamijoyo
Indonesian Journal of Rheumatology Vol. 14 No. 1 (2022): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i2.186

Abstract

Background: Systemic lupus erythematosus (SLE) is a complex autoimmune disease with various clinical and serological manifestations. Previous studies have shown conflicting results about the association of anti-Ro 52 autoantibodies with hematological abnormalities in SLE. We investigated the correlation between anti Ro 52 autoantibody with anemia, leucopenia, and thrombocytopenia in patients with SLE. Methods: Sixty-two bio archives serum of an SLE patient at the Division of Rheumatology, Department of Internal Medicine, Hasan Sadikin General Hospital, Bandung, Indonesia from 2017 to 2019 were enrolled in the study. Anti-Ro 52 levels were examined using the ELISA method. The clinical data, treatment, and hematology paparametersere were analyzed retrospectively. Results: Among 62 bio-archive serum, four subjects were excluded because of incomplete data. Fifty-eight patients, all females were enrolled. We identified 57 (98.3%) subjects corticosteroid, 31 (53.4%) azathioprine and 28 (48.3%) chloroquine. A correlation coefficient of anti-Ro 52 levels and hemoglobin, leukocyte and platelets were -0.037 (p = 0.391), 0.065 (p = 0.315) and 0.092 (p = 0.246), respectively. Conclusion: No correlation was found between anti Ro 52 antibody levels with haematological abnormalities in patients with SLE. Further studies need to evaluate whether other antibodies play important role in haematological abnormalities in SLE.
Progressive Systemic Sclerosis with Interstitial Lung Disease Post Radio Ablation in Graves Disease's Patient: A Case Report Maha Chakri Willheljulya; Sumartini Dewi; Andri Reza
Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology
Publisher : Indonesian Rheumatology Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ijr.v13i2.188

Abstract

Systemic sclerosis (SSc) is a connective tissue disease marked by degenerative microvascular abnormalities and immune system activation, resulting in skin and internal organ fibrosis. The link between thyroid problems and systemic sclerosis is unknown. Although several studies have demonstrated that patients with systemic sclerosis develop Graves' illness as the condition progresses, only a few have reported that Graves' patients develop progressive systemic sclerosis. It is an uncommon instance of multiple autoimmune illnesses in which SSc develops gradually after the birth of the first child and the patient had Graves' disease since the age of 17 and had thyroid ablation 5 years ago. SSc illness has a characteristic clinical appearance, involving the skin to the rest of the body and internal organs, particularly the lungs.

Page 23 of 26 | Total Record : 252

 21   22   23   24   25 

Filter by Year

2009 2023


Reset
Filter By Issues
All Issue Vol. 15 No. 1 (2023): Indonesian Journal of Rheumatology Vol. 13 No. 3: Indonesian Journal of Rheumatology Vol. 14 No. 2 (2022): Indonesian Journal of Rheumatology Vol. 14 No. 1 (2022): Indonesian Journal of Rheumatology Vol. 13 No. 2 (2021): Indonesian Journal of Rheumatology Vol. 13 No. 1 (2021): Indonesian Journal of Rheumatology Vol. 12 No. 2 (2020): Indonesian Journal of Rheumatology Vol. 12 No. 1 (2020): Indonesian Journal of Rheumatology Vol. 11 No. 2 (2019): Indonesian Journal of Rheumatology Vol. 11 No. 1 (2019): Indonesian Journal of Rheumatology Vol. 10 No. 2 (2018): Indonesian Journal of Rheumatology Vol 10, No 1 (2018) Vol. 10 No. 1 (2018): Indonesian Journal of Rheumatology Vol 9, No 2 (2017) Vol. 9 No. 2 (2017): Indonesian Journal of Rheumatology Vol 9, No 1 (2017) Vol. 9 No. 1 (2017): Indonesian Journal of Rheumatology Vol. 8 No. 2 (2016): Indonesian Journal of Rheumatology Vol 8, No 2 (2016) Vol 8, No 1 (2016) Vol. 8 No. 1 (2016): Indonesian Journal of Rheumatology Vol 5, No 1 (2014) Vol. 5 No. 1 (2014): Indonesian Journal of Rheumatology Vol. 4 No. 1 (2013): Indonesian Journal of Rheumatology Vol 4, No 1 (2013) Vol. 3 No. 1 (2011): Indonesian Journal of Rheumatology Vol 3, No 1 (2011) Vol 2, No 3 (2010) Vol 2, No 2 (2010) Vol. 2 No. 2 (2010): Indonesian Journal of Rheumatology Vol 2, No 1 (2010) Vol. 2 No. 1 (2010): Indonesian Journal of Rheumatology Vol. 1 No. 2 (2009): Indonesian Journal of Rheumatology Vol 1, No 1 (2009) Vol. 1 No. 1 (2009): Indonesian Journal of Rheumatology More Issue