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Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
Journal Mail Official
ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
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Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 12 Documents
Search results for , issue "Vol. 34, No. 1 Januari - Maret 2013" : 12 Documents clear
Pencitraan Resonansi Magnetik Kardiovaskular pada Penyakit Jantung Bawaan Oktavia Lilyasari
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.297

Abstract

Pencitraan merupakan suatu hal yang fundamental dalam diagnosis Penyakit Jantung Bawaan (PJB). Pencitraan Resonansi Magnetis Kardiovaskular (Cardiovascular Magnetic Resonance/CMR) menjadi teknik penting dalam diagnosis dan tatalaksana penyakit kardiovaskular. Data contagious 3D yang merupakan kekuatan CMR sangat efektif memberikan gambaran lengkap patologi anatomi PJB sederhana ataupun kompleks. CMR dapat menyajikan gambar tiga dimensi dengan resolusi tinggi dan memungkinkan untuk rekonstruksi visualisasi kelainan jantung yang kompleks.Saat ini pencitraan dengan menggunakan CMR menjadi tekhnik penting dan adekuat dalam menilai fungsi ventrikel, aliran dinamis intra kardiak, termasuk regurgitasi dan stenosis katup, aliran pembuluh darah besar, karakterisasi anatomi kelainan bawaan yang kompleks, terutama yang berhubungan dengan vena sistemik dan pulmonal, hubungan antar ruang jantung (atrioventricular connection, ventriculo-arterial connection). CMR juga dapat mengurangi jumlah prosedur kateterisasi diagnostik untuk evaluasi pre dan post tindakan intervensi bedah maupun non bedah, sehingga dapat meminimalisasi efek radiasi yang ditimbulkan oleh prosedur kateterisasi.Beberapa kesulitan timbul saat melakukan pemeriksaan CMR pada anak yang kecil. Diperlukan beberapa penyesuaian untuk menghasilkan kualitas gambar yang optimal, karena ukuran struktur jantung yang lebih kecil, frekuensi nadi yang lebih cepat, kesulitan atau ketidakmampuan untuk mengikuti komando tahan nafas dan kurangnya kerjasama pasien.Penggunaan klinis CMR tergantung dari usia dan kondisi klinis pasien. Pencitraan Resonansi Magnetik Kardiovaskular menjadi teknik utama terutama pada anak-anak yang cukup besar, remaja atau dewasa pada kelainan anatomi yang kompleks, dan evaluasi post operasi.
Keberhasilan Jangka Panjang Ablasi Radio Frekuensi Takikardia Right Ventricular Outflow Tract Hauda El Rasyid; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.298

Abstract

Background. Right Ventricular Outflow Tract (RVOT) tachycardia is frequentlyfound in clinical practice. Despite of its good prognosis no need itusually affects the reproductive age (20-40 years) and can be very symptomatic.Radio frequency ablation (RFA) is a recommended therapeuticoption of RVOT tachycardia. The aim of this study is to evaluate longtermresultsof RFA in National Cardiovasxular Center Harapan Kita.Method. A retrospective cohort study conducted to subjects with RVOTtachycardia who underwent RFA during period of 2005-2011. Clinicalcharacteristics are revealed from medical record and electrophysiologycharacteristics are revealed from electrophysiology recording system(PruckaTMandWorkmateTM). ECG morphology assessed by 2 observersusing digimatic calliper MitutoyoTM. Patients that received pharmacologicaltherapy act as control group. All patients are observed up to 1 year.Results. Sixty two patients underwent RFA (mean age of 43,56 ± 11,77year,46 female). ECG morphologies are all left bundle branch blok (LBBB),inferior axis, transtitional zone ? V4. Based on ECG morphology, septal siteare majority of cases. Mean EA (earliest activation) is 41,26 ± 16,94 ms,median 39,50 ms. An acute successful rate of RFA is 79%.Long termsuccessrate is 83,9 % as compare to only 40,9% in medical therapy group(RRR77%, p=0.001). Septal origin site is an independent factor of success ofRFA RVOT tachycardia.Conclusion. RFA of RVOT tachycardia is safe and effective with betterlongterm result as compare to pharmacological therapy.
Kajian Rasio EPC dan Ce c Sebagai Prediktor Disfungsi Endotel pada Pasien dengan Kelompok Risiko Tinggi Berdasarkan Framingham Risk Score 10 Years Wiwit Nurwidyaningtyas; Djanggan Sargowo; Achdiat Agoes; Titin Andri W; S Satuman
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.299

Abstract

Research background. Circulating Endothelial Cells (CEC) is a reflection of endothelial damage or endothelial stress, increasing of CEC amount depend on endothelial mechanism, edothelial adhesivity damage and cellular apoptosis as a result of decreasing sitoskleleton function. If higher exposure affects the increasing of CEC amount,VEGF other growth factor mediators will be reflected as endothelial stress manifestation which roles in the increasing of re-population and Endothelial Progenitor Cells (EPC) differentiation. Endothelial Progenitor Cells is a mononuclear cell (a part of stem cell) that could change to be mature endothel and roles in re-edothelialisation and neovascularisation. This research aimed to investigate the ratio of EPC : CEC in risk group through Framingham Risk Score (FRS) 10 years approach as endothelial dysfunction predictor.Research method and result. There were 55 research subjects whom taken by FRS scoring and devided into some risk groups and two control groups. They were control group I (health) and control group II (sick). Base blood was taken to every each of them to analyze their EPC and CEC with Flowcytometry. EPC was analyzed by CD34 Per CP Santa Cruz SC-19621 and CD 133 FITC (fluorescein isothiocyanate) Bioss bs-0395R-FITCmarker.WhileCEC was analyzed CD45 FITC Biolegend 202205 dan CD 146 PE Biolegend 134704 marker. Result showed, there was significant ratio differences of EPC : CEC in those six groups which was proven by p-value 0.032< ? (0.05). The higher ratio was in high risk group (139.06).Conclusion. Research showed that EPC amount was increase related to the increasing of high risk level according to FRS 10 years, but its increasing did not followed by its ability to homing in injury area as role part in re-endothelialisation process. It found that EPC amount was higher in high risk group than in low risk group.
Circulating Endothelial Progenitor Cells is a predictor in Atherosclerosis: Is it really a promising candle? Anwar Santoso
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.300

Abstract

Circulating endothelial progenitor cells (CEPC) are supposed to be a subset of bone marrow-derived peripheral blood mononuclear cells (PBMC), revealing immature surface markers common to hematopoietic stem cells, such as CD 34 and CD 133 and endothelial lineage markers. These cells can be isolated from peripheral, umbilical cord, and bone marrow blood. CD 34 represents a marker of immature stem cells that is commonly used to characterize CEPC together with other surface antigens. Though, as CD 34 is also expressed at lower levels on mature endothelial cells, most recent studies used CD 133, a marker of more immature hematopoietic stem cells that is now considered the best surface marker to define, identify and isolate the CEPC1. CD 133 (also known as AC 133 or prominin) is highly conserved antigen with unknown biological activity. It would be expressed on hematopoietic stem cells, but not on mature endothelial cell and monocytes. In order to reflect the endothelial cells, there is general agreement for the use of at least one additional marker, such as vascular endothelial growth factor receptor-2 (VEGFR-2 or KDR), while others are platelet-endothelial cells adhesion molecules-1 (PECAM-1), von Willebrand factor, c-kit, Tie-2, vascular endothelial-cadherin and VEGFR-12.
Interpretasi Hasil Pemeriksaan MRI Kardiak pada Penyakit Jantung Koroner Sony Hilal Wicaksono; Fachmi Ahmad Muslim; Vienna Rossimarina
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.301

Abstract

Seorang pasien dapat didiagnosis penyakit jantung koroner (PJK) melalui empat cara: kematian jantung mendadak, sindrom koroner akut, angina pektoris stabil paska revaskularisasi, dan hasil diagnostik noninvasif (Computed Tomography scan/CT scan koroner, Single Photon Emission Computed Tomography Myocardial Perfusion Imaging/SPECT MPI nuklir atau Magnetic Resonance Imaging/MRI)1. Pemeriksaan noninvasif memegang peranan penting, yaitu sebagai satu-satunya cara mendiagnosis PJK asimtomatik. Oleh sebab itu, pemahaman mengenai interpretasi hasil pemeriksaan noninvasif seperti CT scan koroner, SPECT MPI nuklir atau MRI kardiak dimasukkan dalam kompetensi dasar program pendidikan spesialis jantung dan pembuluh darah menurut Kolegium PERKI.
Kulit Manggis Menghambat Aktivasi Nuclear Factor ?B (NF-?B) dan Menurunkan Ekspresi ICAM-1 pada Tikus dengan Diet Tinggi Kolesterol H Hendarto; Mohammad Saifur Rohman; Djanggan Sargowo
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.302

Abstract

Background: Atherosclerosis is widely viewed as an inflammatory disease with hypercholesterolemia being a dominant underlying risk factor. This study aimed to determine the effect of mangosteen pericarp in inhibition of NF-?B activation and ICAM-1 expression in rat fed with high cholesterol.Methods and Results: Various doses of crude extract mangosteen pericarp were administered to the high fat diet wistar rats and the activity of NF-?B measured by immunohistochemistry to assess nuclear NF-?B expression and the ICAM-1 expression. The high fat diet resulted significant increased serum LDL levels. Increased nuclear NF- ?B activation and ICAM-1 expression were also observed in high fat diet rats in concurrence with increased serum LDL. The inhibitory effect on NF- ?B activity and ICAM-1 expression was observed when 400 mg of mangosteen pericarp crude extract was administered and even showed a higher inhibitory effect in 800 mg of mangosteen pericap treated rats. The 800 mg extract treatment resulted in decreased ICAM-1 expression similar to those of non high fat rats.Conclusion: The administration of 800 mg mangosteen pericarp crude extract significantly inhibited NF-?B activation and reversed the expression of ICAM -1 to the normal level in high cholesterol diet rats.
Of All Antioxidants, Would One Finally Be Used Clinically For Atherosclerotic Disease? Suko Adiarto
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.303

Abstract

Oxidation of LDL by oxygen free radicals results in unregulated uptake of modified LDL by macrophages in arterial wall. This is considered a key initiating factor for development and progression of atherosclerotic process. It is then logical to hypothesize that anti-oxidants, which can directly scavenge free radicals, can be useful in preventing atherosclerotic process. Initial support for this hypothesis accumulated rapidly from numerous in-vitro studies.
Ablasi Septal pada Pasien dengan Hypertrophic Obstructive Cardiomyopathy pada Pasien dengan Gagal Nafas Jusuf Endang; H Haryadi; Siska Suridanda; Andika S; Roy Christian; I Irmalita; Sunu Budi Raharjo; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.304

Abstract

Hypertrophic Obstructive Cardiomyopathy (HOCM) prevalence is about 1 among 500 population. It is caused by genetic malformation. Dyspnoe, angina pectoris and syncope are clinical manisfestation. Pharmacological and non-pharmacological treatments can be performed to relieve the obstructive symptoms. Recently alcohol septal ablation has been proven improve haemodynamic and functional status.We report a case of HOCM patient with refractory lung oedema and intubated due to respiratory failure that was immediatelly improved afterseptal ablation.
Intervensi Koroner pada pasien Angina Pektoris Stabil: Penggunaan Fractional Flow Reserve sebagai Alat Pengambil Keputusan Angioplasti Januar Wibawa Martha
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.305

Abstract

Coronary angioplasty is a definitive, percutaneous intervention to improve myocardial oxygen supply. The benefit of coronary angioplasty for stable angina pectoris is still a controversy. The COURAGE trial had shown that angioplasty for stable angina pectoris gave no additional benefit compared with optimal medical therapy, while the recently done FAME II trial showed the opposite. FAME II trial proved that angioplasty could reduce MACEs in stable angina pectoris patients. The conflicting results from COURAGE and FAME II trials is due to the difference in decision making methodology used for angioplasty. COURAGE used plain angiogram while FAME II utilized Fractional Flow Reserve (FFR) as a tool to decide whether a lesion should undergo angioplasty. The result of FAME II demonstrate FFR is far more reliable to determine coronary lesion which cause ischemia, hence a better decision making tool for angioplasty. The specificity of FFR is proven high, while angiography has an excessive false positives. The use of FFR before angioplasty is still low although there is a considerable evidence that FFR is a better decion making tool for angioplasty compared to angiography. Health economic analysis displayed the use of FFR for stable angina pectoris is cost effective in the long term.
Seleksi Kandidat Balloon Mitral Valvuloplasty pada Stenosis Mitral Rematik Amiliana M Soesanto
Jurnal Kardiologi Indonesia Vol. 34, No. 1 Januari - Maret 2013
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v34i1.306

Abstract

Balloon Mitral Valvulotomy (BMV), sometimes also referred to as Percutaneous Transcatheter Mitral Commissurotomy (PTMC) is becoming a common treatment option for patients with mitral stenosis. Compared to surgical valvotomy, it has less procedural risk, shorter hospital stay and comparable outcome. However, that good result can only be achieved in selected good candidates. This article will give a highlight of some consideration to choose a good candidate for BMV mostly evaluated by echocardiography.

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