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Raymond Pranata
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Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
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INDONESIA
Indonesian Journal of Cardiology
Published by Indonesian Heart Association
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Arjuna Subject : Kedokteran - Cardiology and Cardiovascular Medicine
Articles 9 Documents
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Search results for , issue "Vol. 36, No. 2 April - Juni 2015" : 9 Documents clear
Benarkah Obat Penghambat Pompa Proton Meningkatkan Risiko Infark Miokard? Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.459

Abstract

Isu tentang pengaruh obat Penghambat Pompa Proton (P3) terhadap kejadian kardiovaskular mayor sudah cukup lama menjadi debat di kalangan kardiologi. Berbagai studi terkait masalah ini telah dilakukan tetapi memberikan hasil yang kontradiktif. Ching dkk1 meneliti hampir 3300 pasien pasca intervensi koroner perkutan yang dibagi jadi dua kelompok yaitu dengan dan tanpa P3. P3 yang dikonsumsi meliputi lansoprazole, pantoprazole, omeprazole dan esomeprazole. Pada pengamatan selama 9 bulan didapatkan insiden mortalitas, revaskularisasi dan kejadian kardiovaskular mayor yang lebih tinggi pada kelompok P3 dengan rasio hazard 1.7. Sebaliknya metanalisis dari 23 studi oleh Kwok dkk memperlihatkan tidak terdapat perbedaan kejadian kardiovaskular mayor pada pasien yang mengkonsumsi klopidogrel dan P3.2Sebuah studi yang dimuat di jurnal terbuka Plos One pertengahan tahun ini cukup mengejutkan kalangan kardiologi. Shah dkk3 melakukan studi observasional dari sekitar 16 juta data rekam medis dan menyimpulkan bahwa obat P3 berhubungan dengan peningkatan risiko infark miokard pada populasi umum. Enam belas persen penderita penyakit refluks gastroesofageal (GERD) yang diberi P3 menunjukkan peningkatan risiko infark miokard (95%IK 1.09 hingga 1.24) dan peningkatan risiko mortalitas kardiovaskular (HR 2.0, 95%IK 1.07 hingga 3.78, p = 0.031).Jadi ada dua isu besar terkait P3, yaitu diduga meningkatkan kejadian kardiovaskular mayor pada pasien penyakit jantung koroner (PJK) dan peningkatan kejadian infark miokard pada populasi umum. Bagaimanakah sikap yang harus diambil oleh para klinisi terkait hal di atas? Tulisan ini merupakan suatu stimulus agar para klinisi melihat lebih seksama pengaruh interaksi P3 pada pasien maupun populasi umum.
Cardiac Cachexia dan Dampaknya terhadap Sintasan Penderita Gagal Jantung Aninka Saboe; Badai B. Tiksnadi; Augustine Purnomowati; Toni M. Aprami
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.460

Abstract

Background. Cardiac cachexia (CC) is one of indicator of poor prognosis in heart failure. Unfortunately, its existence is often overlooked by many cardiologists, this is further complicated by small number of study concerning CC, and the controversial issues they encompasses.Methods. The aim of this study is to analyze the survival in heart failure (HF) patients with cachexia complications. A retrospective cohort study was conducted on the data from Hasan Sadikin General Hospital HF registry from March 2013 – August 2014. The inclusion criteria was the data registry (registry’s inclusion criterias: HF patients above 18 years of age with left ventricle ejection fraction (LVEF) below 40%, time onset of HF more than 6 months and exclusion criterias were valvular diseases as primary etiology of HF). The exclusion criteria was if the patients have other chronic disease (COPD, CKD, cancer). Cardiac cachexia was diagnosed in patients fulfilling the criteria from international cachexia consensus.Results. There were 39 patients, most of them were female (61.5%), with mean LVEF 28.5% (+6.7). Cardiac cachexia was diagnosed in 6 (15.3%) patients. At 6 months of follow-up after initial enrollment, the cumulative rate of death from cardiovascular cause was 83% among cachectic as compared 37.5% among noncachectic patients p=0.001 Adjusted HR (95%CI) = 8.05 (2.40–27.04). There were no association between mortality with sex (p=0.268), etiology of HF (p=0.288), LVEF (p=0.061), comorbid condition (hypertension p=0.237, diabetes mellitus p=0.163).Conclusions. We conclude that patients with cardiac cachexia is independent predictor of death in HF and warrants a special consideration in the management of HF.
Hubungan Kadar Soluble Intercellular Adhesion Molecule-1 dan Soluble Vascular Cell Adhesion Molecule-1 dengan Gradasi Trombosis Atrium Kiri pada Stenosis Mitral Elen Elen; Pramono Sigit; Yoga Yuniadi; Ismoyo Sunu
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.461

Abstract

Background. The relationship between inflammation and coagulation has been widely described, which adhesion molecules play important role in inflammation. Soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) seem to be related to thrombosis in few previous studies. The level of those molecules were increased in mitral stenosis (MS), however their relationship with left atrial thrombosis gradation is still unknown.Methods. Patients with moderate-severe MS (without any significant mitral regurgitation) who underwent transesophageal echocardiography were recruited consecutively in September-October 2013. They were divided into 3 categories of left atrial thrombosis gradation: non-thrombus without dense left atrial spontaneous echo contrast (LASEC) group, and non-thrombus with dense LASEC group, and thrombus group.Results. A total of 39 subjects were enrolled in the study with a mean age of 40.97±9.61 year. Moreover, 71.8% of them were female and 67.7% of them had atrial fibrillation (AF). Evaluation on left atrial thrombosis gradation as mentioned above showed that sICAM-1 levels were 284.74 (218.79-321.00) ng/mL, 346.86 (125.68-698.12) ng/mL, and 395.93 (171.44-1021.53) ng/mL, consecutively (p=0.280). While sVCAM-1 levels gradually increased based on those groups consecutively: 729.01 (543.93-967.80) ng/mL, 1066.00 (581.36-2470.60) ng/mL, and 1158.00 (668.66-2498.30) ng/mL (p=0.016). Multivariate analysis showed that AF and mitral valve area (MVA) influence thrombosis gradation.Conclusion. Difference in sVCAM-1 levels were found among left atrial thrombosis gradation groups in mitral stenosis, but its effect on thrombosis gradation was influenced by AF and MVA.
Pengalaman Awal Tindakan MitraClip di Pusat Jantung Nasional Harapan Kita, Jakarta Prima Almazini; Nani Hersunarti; Rarsari Soerarso; Bambang Budi Siswanto; Doni Firman; Amiliana M Soesanto
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.462

Abstract

Background: Percutaneous mitral valve repair (PMVR) with MitraClip is considered as an optional treatment for patients with significant MR who are high risk for having surgery. This novel therapy is less invasive, safe, and effective for MR reduction, and hence improve symptoms of heart failure, as well as reverse left ventricle remodeling. The purpose of this study was to report the early experience of Mitraclip procedure for treating significant MR at the National Cardiovascular Center Harapan Kita.Methods: This retrospective study was conducted at National Cardiovascular Center Harapan Kita Hospital, Jakarta. The data was retrieved from computerized database and medical records from February 2014 to January 2015, and then analyzed with SPSS.Results: A total of 6 patients with age 51 - 75 years old, underwent MitraClip procedure. Of all patients, the MR were severe in 5 patients and moderate in 1 patient. One was female and 5 were male. Among these patients, 2 were degenerative MR and 6 were functional MR. Two patients were treated with single MitraClip and 4 patients required double MitraClip. Post proccedure, there was reduction of MR to mild was achieved in 2 patients and to moderate in 4 patients. The left ventricular end diastolic dimension decreased from 66 ± 6.5 mm at baseline to 59 ± 7.3 mm (p=0.04) and end systolic dimensions decreased from 50 ± 10.6 mm at baseline to 48 ± 10.0 mm before discharge (p=0.27) as evaluated from predischarge echocardiography. At one month after procedure, 2 patients were in New York Heart Association (NYHA) functional class I and 4 patients were in class II. In-hospital mortality was 0%. Only 1 patient was re-hospitalized after procedure due to heart failure.Conclusion: From our early experience, MitraClip was considered an effective and safe option for patients with functional and degenerative MR who are at high risk for open-heart surgery. Left ventricle dimension, NYHA functional class, MR reduction, and re-hospitalization rate were improved after procedure.
Trombolisis dengan Panduan Kateter pada Pasien dengan Iskemia Tungkai Akut Derajat IIB Yanna Indrayana; Djanggan Sargowo
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.463

Abstract

Acute limb ischemia was defined as sudden decrease in limb perfusion of less than 14 days duration, resulting in variable ischaemic clinical manifestation and potential risk of limb loss. We reported a case female 64 years old with sudden onset of right leg pain in last 3 days with history of hipertension, Diabetes Mellitus and heart failure. From physical examination of lower extremity was found pulselessness, pallor, paresthesi, poikilothermia, paralysis, and pain at the level of A. Poplitea dextra. Diagnosis was confirmed with Duplex Ultrasonography. From arteriography we found thrombus with subtotal occlusion at proximal a. Femoralis dextra and diffuse stenosis at the distal. Operation was not carried out as the request of the patient and it was decided to performed Catheter-directed Thrombolysis. In evaluation there was flow improvement at a. Femoralis dextra but it did not reach peripheral perfussion due to reperfussion injury.
Fibrilasi Atrium pada Penyakit Paru Obtruktif Kronik Silmi Kaffah; Yoga Yuniadi; Erlang Samoedro
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.464

Abstract

Chronic Obstructive Pulmonary Disease (COPD) often coexists with cardiovasculae disease (comorbidities) that may have a significant impact in prognosis. Atrial fibrillation (AF) is the most common comorbid, which is supraventricular tachyarrhythmias uncoordinated and ineffective atrial activation. Emergence of atrial fibrillation if not handled properly associated with morbidity and mortality are high . Exact pathogenesis of AF in COPD but may associated with atrial factors , inflammation ,activation of the renin - angiotensin - aldosterone system (RAAS), coronary heart disease , disorders of the autonomic tone and pharmacological. Complications of AF consisted of thromboembolic events including stroke. The management of AF with COPD should be adjusted to optimize therapeutic result
Regurgitasi Mitral Kronik: Waktu Intervensi yang Optimal Estu Rudiktyo; Amiliana M. Soesanto
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.465

Abstract

Chronic mitral regurgitation is commonly encountered valve disease. In this disease, there is volume overload on the left ventricle leading to left ventricle dilatation and dysfuction. Surgical or percutaneous intervention can improve prognosis, however optimal timing of intervention still controversial. In the past, timing of intervention was based solely on symptoms and left ventricle function. There have been recent advances in our knowledge, diagnosis, and treatment of mitral regurgitation. All of these advances have provided an incentive to change the indication for timing of operations in patients with mitral regurgitation, setting a new paradigm of an early operation before the onset of ventricular dysfunction. In this article we will outline these newer advances and provide recommendations regarding optimal timing of intervention for mitral regurgitation.
Myocardial Bridging: Peran ct dan mri dalam Diagnosis dan Stratifikasi Risiko Sony Hilal Wicaksono
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.466

Abstract

PendahuluanMyocardial bridging (MB) adalah anomali kongenital arteri koroner yang paling umum ditemukan. MB adalah bila terdapat sebagian segmen dari arteri koroner yang berjalan epikardial mengambil jalur menukik ke dalam miokard sehingga menciptakan jembatan di atas segmen arteri koroner tersebut. Insidens MB berdasarkan temuan studi-studi otopsi, didapatkan angka terendah adalah 15% dan angka tertinggi 85%.1 Arteri koroner yang paling sering mengalami myocardial bridging adalah Left Anterior Descending (LAD), yang berdasarkan studi-studi didapatkan angka terendah 67% dan angka tertinggi 98% pasien.2,3 MB dikategorikan termasuk varian normal arteri koroner, dan sebagian besar kasus tidak menampilkan gejala, namun terdapat kasus yang menjadi masalah. Gejala dan gambaran elektrokardiografi yang ditimbulkan oleh iskemia pada MB tidak spesifik sehingga sulit dibedakan dengan iskemia akibat aterosklerosis arteri koroner.4 MB menyebabkan kompresi segmen arteri sehingga terjadi perubahan hemodinamika yang mengakibatkan iskemia, sehingga dapat tampil dengan gejala dan tanda khas iskemia seperti angina, atau temuan iskemia miokard berdasarkan uji stres, datang dengan sindrom koroner akut, temuan disfungsi ventrikel kiri, aritmia bahkan hingga kematian jantung mendadak.5Kemaknaan klinis MB yang tidak spesifik dan rentangnya luas mulai dari dianggap varian normal hingga dapat fatal menjadikan MB perlu mendapatkan perhatian di awal untuk mendapatkan data diagnosis anatomi MB kemudian stratifikasi risiko sesuai kemaknaan fisiologis.
Evaluasi Alat Pacu Jantung Permanen Dari Elektrokardiogram Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 36, No. 2 April - Juni 2015
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v36i2.467

Abstract

KasusSeorang pria, 67 tahun datang ke poli jantung di RSU Jambi dengan riwayat pemasangan alat pacu jantung di RSU Bengkulu 6 bulan yang lalu. Tidak terdapat keluhan dan pasien dapat melakukan aktivitas sehari-hari sebagai seorang pensiunan pegawai negri sipil.Rekaman EKG diperlihatkan pada gambar di bawah ini,

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