cover
Contact Name
Raymond Pranata
Contact Email
raymond_pranata@hotmail.com
Phone
+6282112918892
Journal Mail Official
ijc@inaheart.org
Editorial Address
Editorial Office: Heart House, Jalan Katalia Raya No. 5, Kota Bambu Utara West Jakarta, 11430 - Indonesia Telephone: +62 21 5681149, Fax: +62 21 5684220 Email: ijc@inaheart.org
Location
Kota adm. jakarta barat,
Dki jakarta
INDONESIA
Indonesian Journal of Cardiology
ISSN : 28303105     EISSN : 29647304     DOI : -
Core Subject : Health,
Indonesian Journal of Cardiology (IJC) is a peer-reviewed and open-access journal established by Indonesian Heart Association (IHA)/Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI) [www.inaheart.org] on the year 1979. This journal is published to meet the needs of physicians and other health professionals for scientific articles in the cardiovascular field. All articles (research, case report, review article, and others) should be original and has never been published in any magazine/journal. Prior to publication, every manuscript will be subjected to double-blind review by peer-reviewers. We consider articles on all aspects of the cardiovascular system including clinical, translational, epidemiological, and basic studies. Subjects suitable for publication include but are not limited to the following fields: Acute Cardiovascular Care Arrhythmia / Cardiac Electrophysiology Cardiovascular Imaging Cardiovascular Pharmacotherapy Cardiovascular Public Health Policy Cardiovascular Rehabilitation Cardiovascular Research General Cardiology Heart Failure Hypertension Interventional Cardiology Pediatric Cardiology Preventive Cardiology Vascular Medicine
Articles 712 Documents
Pengaruh Ekstrak Kulit Manggis (Garcinia Mangostana Linn) Sebagai Antioksidan Terhadap Tikus Model Aterosklerotik Muhammad Dicky Hafisalevi; Meddy Setiawan; Djanggan Sargowo
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.55

Abstract

Backgrounds: Atherosclerosis defined by accumulation of Low density Lipoprotein (LDL) and inflammatory cells in tunica intima triggered by oxi-dative stress. Oxidative stress increase the level of Malondialdehid(MDA) which its activity inhibited by superokside dismutase (SOD) as endogenous antioxidant. Extract from pericaps of mangosteen has antioxidants activity that can inhibit the release of free radicals through reactive oxygen species (ROS) are characterized by increased levels of SOD and decrease levels of MDA rats serum. Objectives: aim of this research is to evaluate effect of extract from pericarp of mangosteen (Garcianna mangostana Linn) as antioxidants in rats models of atherosclerosis.Methods: The subjects of the research were 30 white rats (Rattus novergi-cus Strain wistar), divided into 5 groups (negative control, positive control, administration of extract  from pericarp of mangosteen 200, 400, and 800 mg/kg, p.o for 90 days) exploying True Experimental with The Post Test Only Control Group Design.The parameters used in this study is the SOD and MBA are read using spectrophotometry and analyzed by test of ANOVA, BNT1% test, using correlation and regression test.Results and discussion: Based on the statistic analysis, the value of MDA is MDA (r= -0,809; Sig = 0,000 < 0,01 and 2=0,655) and SOD(r = 0,565; Sig= 0,000 < 0,01 and 2=0,391). Whereas oral administration (800 mg/kg) dose of extract from pericap of mangosteen has a good result by increasing the level of SOD and decreasing the level of MDA.Conclusion: This research suggests that extract from pericarp of mangosteen may be potent antioxidant.
Buah Manggis: the Queen of Fruit Faisal Baraas
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.56

Abstract

Ketidak-keseimbangan antara radikal bebas dan antioksidan kini diketahui sebagai penyebab utama dari berbagaipenyakit degeneratif, seperti kanker dan penyakit jantung. Akumulasi radikal bebas yang berlebihan dapat menyebabkan peroksidasi lipid, pro-tein dan DNA di dalam inti sel. Stres oksidatif adalah ketidak-seimbangan antara produksi radikal bebas oksigen dengan antioksidan yang tersedia di dalam sel. Dalam hal-hal tertentu, produksi radikal bebas oksigen dapat meningkat, sementara antioksi dan yang tersedia tidak mencukupi untuk menetralisirnya. Pada orang-orang yang beranjak tua,  kecenderungan itulah yang mudah terjadi, dimana produksi radikal bebas oksigen cenderung meningkat dengan meningkatnya usia, sementara produksi antioksidan di dalam sel ataupun asupan antioksi dan dari luar seringkali sudah mulai cenderung berkurang.
ARB dibandingkan non-ARB dalam Menurunkan Komplikasi Kardiovaskular pada Pasien Hipertensi dengan Risiko Tinggi: Laporan Berbasis Bukti Alvin Nursalim; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.59

Abstract

Background: High risk hypertensive patients have an increased risk of developing cardiovascular complication. It is better to use a proven cardio protective drugs to reduce blood pressure in high risk hypertensive patients. Angiotensin II receptor Blocker (ARB) is one type of antihyper-tensive drugs with cardioprotective effect for hypertensive patients withoutother risk factor. Whether cardioprotective effect of ARB also apply for a more specific population such as high risk hypertensive patients need to be investigated.Aim: To determine the efficacy of ARB compared to non-ARBs in preventing cardiac event in a more specific population, such as high risk hypertensive patients.Methods: A search was conducted on PubMed and Cochrane. The selection of title and abstract was done using inclusion and exclusion criterias. Three original articles were found and used as the evidence tor the clinical question. The selected studies were critically appraised for validity, importance and applicability.Result: According to Sawada et al, the blood pressure lowering effect was similar between valsartan and non-ARB groups. The cardiovascular events in valsartan group is lower compared to non-ARB groups (relative risk: 0.54, 95% confidence interval 0.4-0.7, p< 0.001). The administration of valsartan as compared to non-ARB, also reduce the occurence of angina pectoris (Relative risk: 0.52, 95% Confidence Interval 0.31–0.86, P=0.01058). Cohn JN et al showed that there was no significant differences in the candesartan group in terms of total death and primary endpoints. The only significant finding in this article was the lower rate of diabetes mellitus in the candesartan group.Conclusion: Valsartan, as compared to non-ARB, reduce cardic event in high risk hypertensive patients.
Sindrom Lutembacher Sebuah Penilaian ekhokardiografi Muhammad Barri Fahmi; Amiliana Mardiani; Ganesja M Harimurti
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.60

Abstract

Lutembacher’s syndrome (LS), consisted of Atrial Septal Defect(ASD) and Mitral Stenosis (MS), is a very rare form of cardiac anomaly. Rene Lutembacher’s first described this syndrome in 1916. Currently, any combination of ASD, congenital or iatrogenic and MS, acquired or congenital is referred as LS.By using echocardiography, the hemodynamic of LS could be assesed. Pathophysiologically, the hemodynamic of ASD is related to the magnitude and direction of shunting across the interatrial communication. The determinants of the amount of shunting are the defect size and theventricles relative resistance to inflow. In MS, the restricted in?low leads to increased diastolic pressures in the left ventricle. This resulted in marked accentuation of the left-to-right shunt.We reported a case of a 34 years old female, first came to Harapan Kita National Cardiac Center, in 2010. She was diagnosed with LS, and was planned to have ASD closure and mitral valve repair by surgery. However, she refused to undertake the procedure. In summary, to illustrate the interactions between ASD and MS, the presence of ASD underestimated the severi?y of MS; meanwhile the existence of MS magnified the left to right shunt in patients with ASD.
Sistem Jejaring Pelayanan Kegawat-Daruratan Kardiovaskular di Wilayah DKI Jakarta dan Sekitarnya Surya Dharma; Anna Ulfah Rahajoe; Sunarya Soerianata
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.61

Abstract

A tremendous progress has been made in the management of patients with ST elevation myocardial infarction (STEMI) over the last 20 years. Primary percutaneous coronary intervention (PPCI) is the preferred option for treating STEMI patients, but offering an easy, direct and fast access to this procedure is still difficult due to geographic and structural medical  services differences, especially in developing countries such as Indonesia.Analysis of Jakarta Acute Coronary Syndrome registry 2010 showed a proportion of patients not recieving acute repercusion therapy of 59% from 654 STEMI patients and majority of them  (52%) were from inter-hospital referral. The time from onset of infarction to hospital admission was more than 12 hours in almost 80% cases. Network organization is central to  optimize patient care at the acute stage of an MI and there is a strong need to build a cardiovascular care unit network system that is well organized in Jakarta. This involves a  multidisciplinary approach that should give an appropriate diagnosis and initial treatment with rapid and safe transport to a PCI capable hospital. Thus, harmonizing the activities of all hospitals in Jakarta that will give the best cardiovascular services to the community by providing two acute reperfusion therapy options (PPCI or pharmaco-invasive strategy)  depending on the time needed for the patient to reach the cath-lab.
Sindrom Brugada: Diagnosis dan Tatalaksana Reza Octavianus; Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.62

Abstract

Brugada syndrome associated with high incidence of sudden death in young and otherwise healthy adults in many parts of the world. The Brugada syndrome which is characterized by an  ST-segment elevation in the right precordial ECG leads, is a familial disease that displays an autosomal dominant mode o? transmission with incomplete penetrance. The first and only gene to be linked to Brugada syndrome is SCN5A, the gene that encodes for the subunit of the cardiac sodium channel gene. More than 80 mutations in SCN5A have been linked to the syndrome.Based on ECG characteristics the syndrome divided into three types. Brugada syndrome is definitively diagnosed when a type 1 ST-segment elevation is observed in >1 right precordial lead (V1 to V3) in the presence or absence of a sodium channel– blocking agent, and in conjunction with one of the following: documented ventricular fibrillation (VF), polymorphic ventricular tachycardia (VT), a family history of sudden cardiac death at < 45 years old, coved-type ECGs in family members, inducibility of VT with programmed electrical stimulation, syncope, or nocturnal agonal respiration. Currently, an implantable cardioverter defibrilla?or (ICD) is the only proven effective treatment for the disease.
Very Fast Tachycardia: What is the mechanism? Yoga Yuniadi
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.64

Abstract

Seorang pria umur 59 tahun datang ke UGD Pusat Jantung Nasional Harapan Kita dengan keluhan berdebar sangat cepat disertai rasa sesak dan nyeri dada. Keluhan ini sudah dirasakan sejak 1 jam sebelum masuk rumah sakit. Pemeriksaan fisik terlihat keadaan umum sakit sedang tanpa tanda hipoperfusi. Tekanan darah 105/87 mmHg dengan denyut nadi sulit dihitung karena terlalu cepat. Pemeriksaan laboratorium dalam batas normal kecuali Rekaman EKG di UGD ditampilkan sebagai Gambar 1. Suatu takikardia QRS sempit regular dengan gambaran gelombang P di belakang kompleks QRS dapat merupakan suatu atrioventricular reciprocating tachycardia (AVRT), atrial takikardia/atrial flutter, atau atipikal atrioventricular node reentrant tachycardia (AVNRT). Bagaimana membedakan antara ketiga ke-mungkinan supraventrikular aritmia tersebut?
Penilaian Severitas Regurgitasi Aorta Andre P Ketaren; Amiliana M Soesanto
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.65

Abstract

Aorta regurgitasi (AR) adalah salah satu gangguan katup yang sering ditemukan. Ekokardiografi merupakan salah satu alat bantu diagnostik yang sangat penting untuk mendiagnosa AR serta untuk menilai severitas dari AR. Di siniakan disampaikan metode-metode ekokardiografi yang mudah dipraktekkan sehari-hari namun memiliki sensitivitas dan spesifisitas yang tinggi untuk menilai severitas dari AR.Penilaian severitas AR dengan ekokardiografi menggunakan berbagai modalitas, di antaranya ekokardiografi dua dimensi (2D), colour Doppler, pulsed wave(PW) Doppler dan continuous wave(CW) Doppler. Masing-masing modalitas saling melengkapi satu sama lainnya. Di dalam rekomendasi European Association of Echocardiography(EAE) dan American Society of Echocardiography(ASE) mengenai penilaian regurgitasi katup dengan ekokardiografi, terdapat beberapa metode untuk menentukan severitas dari AR.
Dispersi Qt dan T-Wave Alternans pada Elektrokardiogram dengan repolarisasi Dini Reza Octavianus; Yoga Yuniadi; Budhi Setianto
Jurnal Kardiologi Indonesia Vol. 33, No. 2 April - Juni 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i2.66

Abstract

Background. It has been well known that early repolarization is only normal ECG variant without significant clinical consequences. However, recent studies show variable results of its relation to ventricular arrhythmias occurence. This study is aimed to seek corellation between early repolarization with more established ventricular arrhythmia marker.Methods. Corellation of early repolarization with QT dispersion and T wave alternans (TWA) in comparation with normal ECG pattern was conducted in a cross secional study. QT interval was measured using tangential methods. QT dispersion is defined as difference of longest and shortest QT interval in 12-lead ECG. TWA is determined by means of time domain modified moving average (MMA).Results. Twenty six subjects with early repolarization and 36 subjects with normal ECG participated in this study. Median age was 30 (20-49) years. Maximum TWA are 29. 5 (9 – 81) vs. 27 (5–81) (p= 0.493), and QT dispersion 20.4 (2.8–47.2) vs. 13.2 (2.4–46.0) ms (p=0.053) in early repolarization and normal ECG group respectively.Conclusion. No significant different of QT dispersion and TWA between subjects with early repolarization as compare to that with normal ECG.
Teknologi Terkini dalam Tatalaksana Intervensi Non Bedah Penyakit Jantung Bawaan Radityo Prakoso; Dewi Hapsari Suprobo
Jurnal Kardiologi Indonesia Vol. 33, No. 1 Januari - Maret 2012
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.v33i5.67

Abstract

Dalam dua hingga tiga dekade terakhir bidang intervensi kardiak telah mengalami kemajuan yang pesat baik dalam hal jumlah tindakan dan jenis tindakan. Inovasi teknologi telah menopang kemajuan terapi intervensi non bedah penyakit kardiovaskular pada anak-anak dan usia dewasa. Terapi intervensi telah menjadi terapi alternatif yang cukup diterima pada kasus penyakit jantung bawaan, meliputi penutupan defek atrial (ASD), defek septum ventrikel tipe muskular (VSD muskular), duktus arteriosus paten (PDA), memperlebar stenosis aorta dan pulmonal seperti yang akan dibahas di bawah ini, sehingga pasien tidak selalu harus menjalani pembedahan. Adanya terapi intervensi non bedah ini juga sangat membantu mengurangi prosedur pembedahan yang diperlukan. Sedangkan pada beberapa kasus yang kompleks, apabila pendekatan secara per kutan sulit untuk dilakukan atau pasien juga membutuhkan perbaikan pada kelainan kardiak lain, pendekatan secara hibrid yaitu terapi intervensi bedah dikombinasi dengan intervensi perkutan dapat dilakukan pada penderita penyakit jantung bawaan.

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