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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
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Depo Medroxyprogesterone Acetate Injection was Associated with a Greater Risk of Diabetes Mellitus: a Study at East Jakarta Public Health Centres Bonaville, Edwin
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 2, April 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To study the relationship between the history of contraceptive injection depo medroxyprogesterone acetate (DMPA) exposure with incidence of diabetes mellitus and the associated risk factors. Methods: This is a case-control study conducted in 6 Public Health Centers in East Jakarta involving 30 cases of diabetes mellitus and 61 controls. Body mass index (BMI), parity, type of contraception, duration of contraceptive use, history of gestational diabetes and breastfeeding were assessed in each group. Data were analyzed with Chi Square or Fisher’s test, and logistic regression. Results: The mean age of the subjects was 45.00 (35-67) years, with a median number of parity of 3.00 (0-7), and the median of BMI was 27.31 (15.24 to 40.27). The number of DMPA injections users was 31.9% and the mean duration of contraception usage was 5.36 ± 4.42 years. There was a correlation between the history of DMPA injections with incidence of diabetes mellitus, with an odds ratio of 3.36 95% CI [1.098 to 10.469]. The risk persisted after adjustment of age and BMI. Conclusion: DMPA exposure was associated with a greater risk of diabetes mellitus. Risk was associated with length of use and persisted after adjusment with age and BMI. [Indones J Obstet Gynecol 2012; 36-2: 100-4 Keywords: depo medroxyprogesterone acetate (DMPA), diabetes mellitus
Kadar D-dimer pada ibu hamil dengan preeklampsia berat dan normotensi di RSUP Dr. Kariadi BIRAWA, A.D.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 2, April 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengetahui dan menganalisis kadar D-dimer sebagai penanda terjadinya preeklampsia berat. Bahan dan cara kerja: Dari bulan Mei - Agustus 2007 dilakukan penelitian potong lintang secara konsekutif di Poliklinik Hamil (145), Instalasi Gawat Darurat (IGD), Kamar Bersalin RSUP Dr. Kariadi/FK. UNDIP Semarang. Semua ibu hamil dengan umur kehamilan > 20 minggu dan memenuhi kriteria preeklampsia berat dan kriteria normotensi dilibatkan dalam penelitian ini setelah sesuai kriteria inklusi serta mendapatkan penjelasan dan mengikuti persetujuan ikut dalam penelitian. Materi pemeriksaan D-dimer diambil dengan cara pengambilan darah vena sebanyak 3cc yang dicampur lithium heparin. Sampel darah diperiksa kadar D-dimer dengan menggunakan alat CARDIAC Ddimer. Data dianalisis secara deskriptif, uji Mann Whitney dan uji korelasi Spearman menggunakan SPSS for Windows v. 15. Bermakna apabila p
Characteristics of Maternal Mortality Cases in a Tertiary Hospital Indarti, Junita; Irawan, Ferry Y
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1251.405 KB) | DOI: 10.32771/inajog.v4i3.431

Abstract

Objective: To identify the characteristics of maternal mortality cases in a tertiary hospital in Jakarta, including socio-demographic characteristics, previous medical and obstetric history, and patient’s clinical condition on arrival at the hospital. Method: This was a survey to identify the descriptive data of maternal mortality cases through medical records during study period. Manual review of 51 medical records was conducted for 2 years from January 2013 to December 2014 in Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital (RSCM). Result: Of 51 cases of maternal deaths, 46 subjects (90.19%) had nine years of minimum education background. There were two subjects less than 21 years old and another was 42 years old. None of these subjects were using intrauterine device (IUD) or implant as the contraceptive methods where 66.6% subjects with underlying disease never used contraception. Ninety-two percent of subjects did antenatal care (ANC) regularly and 80.4% (41 subjects) of them was done in midwives. There were 14 subjects (29.78%) who had ANC in the first trimester of pregnancy. Severe preeclampsia is the most prevalent complication in pregnancy (26 subjects, 65%), which all (100%) patients arrived at RSCM with HELLP Syndrome. Therefore, preeclampsia was the leading cause of death in RSCM. Conclusion: The characteristics of maternal death in RSCM are prevalent in the group of 25-34 years old with the high school as the educational background. Most of them are multiparity and do not use the long-term contraceptive methods. Preeclampsia is the major cause of maternal death in RSCM. Keywords: maternal mortality, risk factors, tertiary hospital
A Comparison between the Level of Interleukin 10 (IL-10) in Aterm and Preterm Labor Lisangan, Yusri
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 4, October 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To compare the level of interleukin 10 in aterm and preterm labor. Method: The research was conducted from November 1st 2011 until January 31st 2012. The subjects were pregnant women underwent labor during the period who had agreed to participate in this study. The study was conducted in the Obstetrics and Gynecology departments of several teaching hospitals of Hasanuddin University in Makassar. The study design was cross sectional with 48 samples. The data were analysed by using the Mann Whithney test. Results: The result revealed that there was an increase of interleukin 10 level in mothers with preterm labor, in comparison with the control group (p < 0.05). Conclusion: The level of interleukin 10 in mothers with preterm labor are higher than aterm labors less than espective. [Indones J Obstet Gynecol 2012; 36-4: 163-6] Keywords: interleukin 10, preterm labor
Relation between CYP17 Polymorphism and Hyperandrogenemia in Polycystic Ovarian Syndrome Wiweko, Budi
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 1, January 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To find 5-untranslated region polymorphism of CYP17 gene and its connection with hyperandrogenemia in polycystic ovarian syndrome. Methods: A cross sectional descriptive study with consecutive random sampling method. Body mass index, ovarian morphology by ultrasonography, fasting insulin level, fasting blood glucose level, 17-hydroxyprogesterone level, total testosterone level, serum hormone binding globulin level, and CYP17 gene polymorphism in 45 subject with PCOs and 45 control subject who attend Yasmin clinic of Cipto Mangunkusumo General Hospital with menstruation problems were measured. CYP17 gene polymorphism was evaluated using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method with MspA1 restriction enzyme. Results: In PCOs group, the genotype distribution were; 11.1% subject with genotype CC, 71.1% subject with genotype TC and 17.8% subject was wild type TT. In non PCOs group, the genotype distribution for CC, TC and TT respectively were 13.3%, 46.7% and 40%. There was significant difference between both group in distribution of TC and TT genotype, with p value 0.013. Frequencies of allele c and allele t in PCOs group were 47% and 53%. In non PCOs group, frequency of allele c and t were 37% and 63%. There were tendency for higher frequency of allele c in the PCOs group but the difference was not statistically significant. Median FAI value for genotype CC homozygote, TC heterozygote and TT homozygote in PCOs group respectively were; 6.82 (6.07 - 8.23); 5.59 (0.25 -21.45) and 4.74 (3.48 - 8.88). There was tendency for increase FAI value in PCOs group corresponds to variant allele, but the result was not statistically different. Conclusion: There were higher proportion of CC homozygote and TC heterozygote genotype in PCOs patient with tendency of increasing FAI value. [Indones J Obstet Gynecol 2011; 35-1: 3-7] Keyword: polycystic ovarian syndrome, free androgen index, CYP17 polymorphism
index INAJOG, INAJOG
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (76.618 KB) | DOI: 10.32771/inajog.v4i4.454

Abstract

N/A
Kanker Serviks: Penyakit Keganasan Fatal yang Dapat Dicegah SUWIYOGA, K.
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 1, January 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

N/A
Ki-67 Expression is Correlated with Cyst Size and Stage of Endometriosis Alif, Muhammad
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To analyze the association between Ki-67 expression with the cyst size and stage of endometriosis, and the correlation strength between them. Methods: A cross-sectional analytic observational study involving 56 paraffin blocks from subjects diagnosed with endometriosis, who had undergone laparotomy or laparoscopic surgery. The study is conducted in Dr. Hasan Sadikin Hospital in September-November 2012. Results: Shows a significant association between Ki-67 expression and the size of endometriotic cyst (p < 0.0001), also with a strong correlation (r = 0.55) according to Guilford criteria. There is also a significant association between Ki-67 expression and the endometriosis stage (p < 0.0001), with a strong correlation (r = 0.564) according to Guilford criteria. Conclusion: Ki-67 expression is correlated with the cyst size and stage of endometriosis. [Indones J Obstet Gynecol 2013; 1-3: 124-8] Keywords: endometriosis stage, endometriotic cyst size, Ki-67
Tantangan, Harapan dan Pengobatan Alternatif dalam Meningkatkan Produktivitas dan Kualitas Hidup Wanita Menopause* RAMBULANGI, J.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 2, April 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Fitoestrogen yang berasal dari tumbuh-tumbuhan dan memiliki struktur kimia serta fungsi biologi menyerupai estradiol diharapkan dapat dimanfaatkan untuk mengatasi permasalahan kesehatan wanita menopause yang terkait dengan rendahnya kadar estrogen.
Expression of p16INK4a Biomarker has a Diagnostic Value in Predicting the Progressivity of Precancerous Cervical Lesion Indarti, Junita
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 3, July 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To evaluate clinical value of p16INK4a biomarker level, by doing p16INK4a immunocytochemistry staining, as a predictor of progressivity of precancerous cervical lesion. Method: Design of this research is case-control study which will be stratified. Research was conducted in Cytology Laboratorium, Gynecology Specialistic Division, Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital from August 2007 to September 2008. Immunocytochemistry examination was conducted in Anatomic Pathology Department, Dr. Hasan Sadikin Hospital. We divided the sample into two categories; patients with and without cervical intraepithelial neoplasia (CIN). This research will evaluate HPV infection and p16INK4a biomarker by doing p16INK4a immunocytochemistry (ICC) staining. Results: We have done immunocytochemistry examination in 130 patients, 26 without CIN and 104 with CIN. Immunocytochemistry cut-off point level is 50, which means value < 50 means low (L) p16INK4a expression and in reverse, value ≥ 50 means high (H) p16INK4a expression. The bivariate analysis of our study were p16INK4a (H) expression has the risk of CIN 1 with OR 8.4, for CIN 2 with OR 13 and for CIN 3 with OR 21, greater than p16INK4a (L) with all p values are significant. ICC p16INK4a (H) expression, age, number of sexual partners, and education are contributory to the risk of progressivity in CIN. The multivariate analysis demonstrates, ICC expression of p16INK4a (H) has a risk (OR) of CIN 1 17.19 times greater than p16INK4a (L); p16INK4a (H) expression’s OR for CIN 2 is 25.56; and for OR CIN 3 is 37.32. The expression of p16INK4a has a significant p value and high OR, thus ICC expression of p16INK4a is suggested to be included in the algorithm of precancerous cervical lesion guidelines and scoring of probability of CIN as an alternative to HPV DNA considering less cost of the test. In this research, we found a scoring model to determine probability of progressivity in precancerous cervical lesion. Conclusion: The expression of p16INK4a has a diagnostic value in predicting the progressivity of precancerous cervical lesion. [Indones J Obstet Gynecol 2010; 34-3: 125-30] Keywords: p16INK4a expression, immunocytochemistry, predictor of progressivity, precancerous cervical lesion

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