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Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)

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Published by Perkumpulan Obstetri dan Ginekologi Indonesia

ISSN : 23386401 EISSN : 23387335 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology Public Health

The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.

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Articles 1,760 Documents

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The Comparison of Clinical and Surgical Staging of Cervical Cancer: A Retrospective Study on Patients at Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia Pradipta, Bram
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 1, January 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To evaluate the accuracy of clinical examination in determining the stage of operable cervical cancer and the extent of the disease. Method: The study involved 58 subjects from outpatient, emergency unit, and ward of Department of Obstetrics and Gynecology Dr. Cipto Mangunkusumo Hospital, from January 2008 to December 2010 with a diagnosis of cervical cancer. Patients who were diagnosed with cervical cancer up to stage IIA were included and patients lost to follow-up, receiving preoperative neo-adjuvant chemotherapy, and died before getting treatment were excluded. The outcomes evaluation were postoperative clinical staging, including the presence of enlarged lymph nodes, parametrial involvement, and tumor size. Lymph nodes, parametrial, and the tumor size were assessed from the surgery and pathological anatomy results. Result: The age distribution of 58 subjects ranged from 25 to 70 years (mean 48.39 years, SD 8.82). Squamous cell carcinoma was the most frequent type (44.9%), followed by adenocarcinoma (24.1%). Errors in preoperative clinical staging compared with postoperative was 40% in stage IA1, 9.52% in stage IB1, 17.65% in stage IB2, and 7.14% in stage IIA. Sensitivity, specificity, positive predictive value, and negative predictive value for preoperative clinical examination of lymph nodes were 11.1%, 100%, 100%, and 85.96%. Sensitivity, specificity, positive predictive value, and negative predictive value for preoperative clinical examination of parametrial involvement were 37.5%, 100%, 100%, and 90.90%. Sensitivity, specificity, positive predictive value, and negative predictive value for preoperative clinical examination of the tumor size were 91.84%, 88.89%, 97.83% and 66.67%. Conclusion: Clinical examination has limitation, especially in determining lymph nodes and parametrial involvement. Other diagnostic modalities in determining the extent of the disease is necessary. Enforcement of the right diagnosis in patients with cervical cancer is needed to determine the appropriate treatment. [Indones J Obstet Gynecol 2011; 35-1: 25-9] Keywords: staging, cervical cancer, preoperative, postoperative

Incidence and Audit of Treatment on Third and Fourth Grade Perineal Tear Santoso,, Budi I; Pamungkas, Satriyo
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 1, January 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To describe the incidence of 3rd and 4th grade perineal tear in Dr. Cipto Mangunkusumo hospital on the period of 2011 - 2014 and its compatibility of treatment based on RCOG guidelines. Methods: Data were collected through medical records on women who had vaginal delivery in Dr. Cipto Mangunkusumo hospital from January 2011 to December 2014. This was a descriptive study with cross sectional design. Results: The incidence of 3rd and 4th grade perineal tear each year were 3.55%, 4.35%, 3.95%, and 1.77% consecutively. About 100% treatment were accompanied by consultant; 3.5% performed in operating theatre; 90.7% were given postoperative antibiotic; 42.2% were given urinal catheter in 1x24 hour postoperative; 100% were given analgesic. About 61.4% of procedures were not compatible with RCOG guidelines. Conclusion: The study showed that the incidence of 3rd and 4th grade of perineal tear was 3.66% for 4 years and the compliance to RCOG standard was 38.6%. [Indones J Obstet Gynecol 2017; 5-1: 35-41] Keywords: incidence, RCOG, third and fourth grade of perineal tear, treatment

Kajian pemberian neoadjuvant kemoterapi pada karsinoma ovarium stadium lanjut di RS Dr. Cipto Mangunkusumo tahun 2000 - 2005 FAUZIAH, I.; ANDRIJONO, ANDRIJONO
Indonesian Journal of Obstetrics and Gynecology Volume. 31, No. 2, April 2007
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Tujuan: Mengevaluasi pemberian perioperatif neoadjuvant kemoterapi pada penderita karsinoma ovarium stadium lanjut di RS Dr. Cipto Mangunkusumo Jakarta, serta mengetahui pencapaian sitoreduksi optimal, morbiditas pembedahan dan kualitas hidup. Rancangan/rumusan data: Studi retrospektif deskriptif pada pasien karsinoma ovarium lanjut yang mendapat neoadjuvant kemoterapi antara 1 Januari 2000 hingga 30 Juni 2006. Bahan dan cara kerja: Data diambil secara berurutan dari status penderita karsinoma ovarium stadium lanjut yang ada di catatan medik rawat inap dan rawat jalan di bagian Obstetri dan Ginekologi RS Dr. Cipto Mangunkusumo Jakarta antara 1 Januari 2000 hingga 30 Juni 2006. Data yang diperoleh diolah dengan menggunakan program statistik SPSS 12. Hasil: Didapatkan 29 pasien selama kurun waktu penelitian. Pemilihan pasien yang akan diberi neoadjuvant kemoterapi tidak berdasarkan pada nilai CA 125 > 500 U/mL, serta tidak berdasarkan temuan ascites dan efusi pleura. Kemungkinan berdasarkan dari keadaan umum pasien, sayangnya data tersebut tidak diperoleh pada penelitian ini karena ketidaklengkapan data. Dari 29 pasien tersebut, 8 pasien respon terhadap terapi dan kemudian dilakukan pembedahan. Pencapaian sitoreduksi optimal pasien karsinoma stadium lanjut yang diberikan neoadjuvant kemoterapi sebesar (37,5%), lebih tinggi dibandingkan penelitian multicenter pada terapi konvensional yang hanya 20-30%. Namun, belum dapat dilihat bahwa pemberian neoadjuvant kemoterapi juga dapat menurunkan morbiditas pembedahan dan memperbaiki kualitas hidup pada pasien dengan keadaan umum buruk, karena ketidaklengkapan data. Kesimpulan: Sitoreduksi optimal dilakukan pada 37,5% pasien yang mendapat neoadjuvant kemoterapi, lebih tinggi dibandingkan dengan pencapaian dengan terapi konvensional. Belum didapatkan perbedaan dalam hal morbiditas dan perbaikan kualitas hidup. [Maj Obstet Ginekol Indones 2007; 31-2: 86-91] Kata kunci: karsinoma ovarium stadium lanjut, neoadjuvant kemoterapi, residu tumor, perdarahan, perawatan ICU, kualitas hidup

Management of Abnormal Cervical Cytology: Atypical Squamous Cells of Undetermined Significance (ASC-US) and Atypical Squamous Cells cannot exclude High Grade Intraepithelial Lesion (ASC-H) Liedapraja, Mediana s.
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To review for the management of abnormal cervical cytology: atypical squamous cells of undetermined significance (ASCUS) and atypical squamous cells cannot exclude high-grade intraepithelial lesion (ASC-H) as a treatment of cervical precancerous lesions in order to avoidexcessive treatment, reduce of unnecessary examinations and to provide cost effectively. Method: Literature study on published literatures and studies about the management of cervical cytology. Conclusion: The results of ASC-US cervical cytology and ASC-H is aninitial screening to detect precancerous cervical lesions. Definitive therapy should be done when finding a low-grade lesions (LSIL) and high degree of lesion(HSIL) squamous intraepithelial. A clinician expected to understand the natural history of HPV infection and the management of precancerous cervical lesions properly. [Indones J Obstet Gynecol 2013; 37-3: 166-170] Keywords: ASC-H, ASC-US, cervical cytology abnormalities, cervical precancerous lesion.

Laceration Extension in Median and Mediolateral Episiotomy Utama, Bobby I; Junizaf, Junizaf; Santoso, Budi I; Ermawati, Ermawati; Hakim, Surahman
Indonesian Journal of Obstetrics and Gynecology Volume. 3, No. 1, January 2015
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To compare the laceration extension between median and mediolateral episiotomy in women with perineal body sized more than 2.5 cm. Method: A single‐blind RCT study was conducted on 104 women receiving median episiotomy and 104 women receiving mediolateral episiotomy at Dr. M. Djamil Hospital Padang and Reksodiwiryo Military Hospital Padang. Result: There was no difference in laceration extension in both groups, but pain in the first 24 hours and pain after day 14 was higher on mediolateral group than the median group (p=0.005 and p=0.008, respectively). Conclusion: There is no difference in terms of laceration extension between median and mediolateral episiotomy, but the pain is higher in the mediolateral group. [Indones J Obstet Gynecol 2015; 1: 38‐43] Keywords: laceration extension, median episiotomy, mediolateral episiotomy

Postlaparoscopic GnRHagonist Therapy does not Improve Spontaneous Conception Rates of Women with Endometriosis Tjandraprawira, Kevin D; Djuwantono, Tono
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 2, April 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the reproductive benefits of combining laparoscopic surgery with GnRH-agonist hormonal therapy in treating women with endometriosis. Methods: This is a non-randomized prospective analytic study of patients with endometriosis conducted in a private hospital in Bandung during the period of January 2014 to December 2015, whom were later followed up after 12-24 months for assessment of post-surgical reproductive performance. A total of 121 patients were enrolled, 60 of which received post-surgical GnRH-agonist hormonal therapy. Results: We discovered that 56 women (46.3%) eventually achieved spontaneous conception after surgery but upon further analysis, it was discovered that GnRH-agonist played no significantly meaningful role in improving the spontaneous pregnancy rates of these patients (OR 1.539; 95% CI 0.750-3.159; p-value 0.239). Furthermore, even though there was a wide range as to when they achieved conception, those untreated with hormonal therapy tended to conceive far more quickly than those who were (5.91 ± 6.28; 8.56 ± 4.24; p-value: 0.011). Conclusion: Post-laparoscopic GnRH-agonist administration to women with endometriosis does not significantly improve their chances of spontaneous conception. In fact, such administration seems to delay it. [Indones J Obstet Gynecol 2017; 5-2: 87-93] Keywords: endometriosis, GnRH-agonist, laparoscopy

Etiologies of Male Infertility in Dr. Cipto Mangunkusumo Hospital, Jakarta Seno, Doddy H.
Indonesian Journal of Obstetrics and Gynecology Volume. 35, No. 3, July 2011
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To have description about the etiologies of male infertility in Dr. Cipto Mangunkusumo Hospital. Method: This was a retrospective study of 315 male infertility patients treated at the Urology Department Dr. Cipto Mangunkusumo Hospital from January 2009 to June 2011. Result: There were 78 patients excluded from the analysis due to incomplete or missing data. The available data consisted of 237 males, with a median age of 35 years old. The median duration of infertility was 4 years. Primary infertility was identified in 89.4% and secondary infertility in 10.6% of all cases. Semen analysis results were classified as normal 2.5%, aspermia 1.3%, azoospermia 41.4%, multiple abnormal parameters 38.0%, single abnormal parameter (oligozoospermia 7.6%, asthenozoospermia 6.8%, teratozoospermia 2.1%), and cryptozoospermia 0.4%. From 237 subjects, there were 39 men (15.9%) with multiple etiologies of male infertility. The most common etiology in this study was varicocele (48.5%). Other etiologies were idiopathic 27.8%, acquired factors 14.3%, obstruction 8.0%, congenital anomalies 6.3%, urogenital infection 2.5%, sexual factors 2.1%, endocrine disturbance 2.1%, no demonstrable cause 1.3%, and other abnormalities 0.8%. This study also found Y-chromosome microdeletions in 2.5% of subjects or 6/98 (6.1%) of azoospermic patients. Lifestyle factors associated with male infertility were smoking 31.6%, alcohol consumption 13.4%, hot-bathing 6.7%, and sauna 2.9%. Conclusion: There are numerous possible contributing factors of male infertility, and varicocele was the most commonly identified etiology in this study. Some of our patients were presented very late for infertility treatment, therefore prompting the necessity to increase general awareness of male infertility in the society. [Indones J Obstet Gynecol 2011; 35-3: 130-4] Keywords: azoospermia, varicocele, risk factor

Prevalensi penderita Overactive Bladder pada pegawai perempuan di lingkungan Departemen Obstetri dan Ginekologi RSUPN Dr. Cipto Mangunkusumo Jakarta AGUSTINA, N.; SANTOSO, B. I.; JUNIZAF, JUNIZAF
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 2, April 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Tujuan: Mengetahui prevalensi penderita overactive bladder (OAB) pada pegawai perempuan di Lingkungan Departemen Obstetri dan Ginekologi RSUPN Dr. Cipto Mangunkusumo Jakarta serta mengetahui sebaran gangguan OAB tersebut menurut beberapa faktor risiko seperti usia, paritas, cara persalinan, status menopause, obesitas dan riwayat operasi histerektomi. Rancangan/rumusan data: Studi observasional deskriptif dengan rancangan potong lintang. Bahan dan cara kerja: Penelitian ini dilakukan pada 250 orang responden yang bekerja di lingkungan Departemen Obstetri dan Ginekologi RSUPN Dr. Cipto Mangunkusumo Jakarta yang memenuhi kriteria, tanpa batasan usia, yang dipilih secara acak. Lalu diberikan kuesioner yang terdiri dari beberapa pertanyaan dan dilakukan pengukuran tinggi dan berat badan untuk menentukan besarnya nilai indeks massa tubuh (IMT) responden tersebut. Bagi responden yang menunjukkan gejala-gejala OAB dilakukan pemeriksaan urinalisa untuk menyingkirkan adanya infeksi saluran kemih maupun glukosuria. Kemudian bagi responden yang memiliki hasil urinalisa dalam batas normal diberikan lembaran daftar harian berkemih untuk membuktikan adanya pola gangguan OAB. Responden yang terbukti mengalami gangguan OAB tersebut selanjutnya dilakukan pemeriksaan fisik guna menyingkirkan adanya kelainan organ. Hasil: Dari 250 orang responden didapatkan 89 orang (35,6%) yang mengaku mengalami gangguan berkemih (inkontinensia urin) dan sebanyak 66 orang di antaranya menunjukkan gejala klinis OAB sesuai definisi yang telah ditetapkan oleh The International Continence Society (ICS) tahun 2002. Rerata usia subjek penelitian OAB ini adalah 40,8 tahun dengan usia termuda 20 tahun dan usia tertua responden adalah 65 tahun. Responden terbanyak adalah pada kelompok usia 40 hingga 49 tahun yaitu sebanyak 90 orang (36%). Dari 66 orang responden yang menunjukkan gejala OAB terdapat 40 orang (60,6%) yang memiliki hasil urinalisa dalam batas normal, terdapat 21 orang (31,8%) glukosuria, dan yang terdeteksi adanya infeksi saluran kemih (ISK) pada penelitian ini ada 5 orang (7,5%). Setelah dikonfirmasi melalui lembaran daftar harian berkemih pada 40 orang responden yang dicurigai menderita OAB tersebut yaitu yang mempunyai hasil urinalisa dalam batas normal, didapatkan 39 responden yang terbukti menderita gangguan OAB serta tidak ditemukan adanya kelainan pada pemeriksaan fisik. Sehingga ketigapuluhsembilan orang inilah yang akhirnya didiagnosa sebagai penderita OAB (15,6) dengan 31 orang di antaranya merupakan tipe campuran, yaitu selain menderita SIU ia juga menderita OAB secara bersamaan. Usia rerata subjek penderita OAB yang berjumlah 39 orang tersebut adalah 44,5 tahun dengan nilai SD 7,5. Pada penelitian ini terlihat kecenderungan timbulnya gangguan OAB dengan pertambahan usia, cara persalinan pervaginam khususnya dengan bantuan ekstraksi vakum, jumlah paritas, status menopause, obesitas serta riwayat operasi histerektomi. Kesimpulan: Prevalensi penderita OAB pada pegawai perempuan yang bekerja di lingkungan Departemen Obstetri dan Ginekologi RSUPNCM Jakarta adalah 15,6% (39 orang). Faktor usia, cara persalinan, paritas, status menopause, obesitas, dan riwayat operasi histerektomi merupakan faktor-faktor yang cenderung berpengaruh terhadap timbulnya gangguan OAB. [Maj Obstet Ginekol Indones 2008; 32-2: 82-92] Kata kunci: overactive bladder, urge inkontinensia, stres inkontinensia urin, daftar harian berkemih

Higher Preoperative Endometrial Cancer Risk Showed More Advanced Stage Iskandar, Jasmine
Indonesian Journal of Obstetrics and Gynecology Volume. 2, No. 2, April 2014
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Objective: To evaluate the preoperative endometrial cancer risk as a guidance to choose the type of surgical approach based on European Society for Medical Oncology guideline (2009). Method: Cross-sectional study involved 73 endometrial cancer patients of Dr. Cipto Mangunkusumo Hospital, from January 2006 to December 2012 which obtained from medical record. The inclusion criteria were endometrial cancer patients with complete D&C, ultrasonographic, and postoperative histopathological reports. Endometrial cancer risk of recurrence was classified according to ESMO 2009 and final diagnosis and stage based on FIGO. Result: From 405 patients, only 73 patients had complete reports. Most of the them were postmenopausal (54.8%), non-nulliparity (79.9%), and obese (49.5%) women. According to risk of recurrence stratification, low, intermediate and high risk were found in 12 patients, 27 patients, and 34 patients. Based on FIGO, there were 60.2% early and 39.8% advanced stage. In high risk group, rates of advanced stage were prominent compared to other groups. There were 38.3% patients with postoperative positive lymph nodes metastases. Conclusion: Most of the endometrial cancer patients were preoperatively diagnosed as high risk. The commonest stage after surgical examination were IIIC. High risk of recurrence showed more positive lymph node compared to low or intermediate risk. Result of preoperative histopathological and myometrial invasion compared to postoperative results were showed to be inconsistent. Patients with â¥ 2 myometrial invasion had more positive lymph nodes metastases. Endometrial cancer risks compared to FIGO stage showed the higher the risk, the more advanced the stage were. [Indones J Obstet Gynecol 2014; 2: 99-105] Keywords: endometrial cancer, FIGO stage, high risk, histological type, intermediate risk, low risk, lymph node.

INDEX Volume 5, No. 1 - 4 2017 Subaktiansyah, Eko; Della, Frachma
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

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eko subaktiansyah

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