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INDONESIA
Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia)
Published by Perkumpulan Obstetri dan Ginekologi Indonesia
ISSN : 23386401     EISSN : 23387335     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The Indonesian Journal of Obstetrics and Gynecology is an official publication of the Indonesian Society of Obstetrics and Gynekology. INAJOG is published quarterly.
Arjuna Subject : -
Articles 1,760 Documents
 7   8   9   10   11 
Laparoskopi Oklusi Tuba Anestesi Lokal (LOTAL) SUHADI, A.
Indonesian Journal of Obstetrics and Gynecology Volume. 33, No. 1, January 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Untuk mengevaluasi ’Laparoskopi Oklusi Tuba dengan Anestesi Lokal’ (LOTAL) sebagai sterilisasi perempuan di RS Setjonegoro Wonosobo Jawa Tengah. Bahan/cara kerja: Penelitian analitis deskriptif bersumber dari data sekunder pada 666 kasus LOTAL di RS Setjonegoro Wonosobo Jawa Tengah dalam periode 2007. Kanula Rubin dimasukkan ke serviks uteri, pasien Trendelenburg dalam posisi lithotomi. Anestesi lokal dengan Lidocain 1% 10 ml disuntikkan sub-umbilikal. Pneumoperitoneum dilakukan dengan memasukkan gas CO2 2,5 liter ke dalam rongga perut. Sterilisasi Laparoskopi dilakukan dengan satu sayatan subumbilikal, dan tuba dilakukan oklusi dengan menggunakan cincin Fallope atau elektrokauter bipolar. Hasil: Selama tahun 2007 LOTAL dikerjakan pada 666 kasus dengan periode interval tanpa mondok. Dalam periode yang sama dilakukan tubektomi dengan metode bedah terbuka 22 dan vasektomi 26 kasus. Waktu rata-rata 10 - 15 menit. Kehamilan terjadi pada satu kasus (0,15%). Sebagian besar kasus pulang 2 jam pascatindakan. Tidak ditemukan kematian dan komplikasi yang berarti. Kesimpulan: LOTAL cukup aman, efektif dan akseptabel sebagai sterilisasi perempuan. [Maj Obstet Ginekol Indones 2009; 33-1: 56-60] Kata kunci: LOTAL, angka kegagalan kehamilan, sterilisasi perempuan
Vitamin D Supplementation to Reduce the Risk of Preeclampsia: Is It True? Sungkar, Ali
Indonesian Journal of Obstetrics and Gynecology Volume. 4, No.3, July 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.229 KB) | DOI: 10.32771/inajog.v4i3.430

Abstract

N/A
Fertility Outcomes after Laparoscopic Reversal of Tubal Sterilization Hadisaputra, Wachyu
Indonesian Journal of Obstetrics and Gynecology Volume. 36, No. 3, July 2012
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To know pregnancy outcome in the tubal reversal of sterilized women. Method: Literature review. Results: Sterilization is considered the most common contraception methods in United States of America, approximately 39% women in reproductive age (15 - 44 years) used this method. However, approximately 15% of these patients deplored this decision due to the influence of their own environment and some factors, such as: young age, the death of a child, the disability of child, and change of partner/ remarried. Tubal reanastomosis or tubal reversal is a surgical procedure that attempts to restore the fallopian tube patency following sterilization. To date, the modern procedure is performed by doing an excision of the tubal segment and reanastomosis by transabdominal laparoscopy. Recently, the laparoscopic technology has developed and evolved rapidly as the robotic assisted laparoscopy was invented. There is alternative method for restoring the fertility in sterilized women who regretted the decision of being sterilized. Unlike the tubal reversal which is conducted in order to restore the tubal function, the IVF is performed to bypass the function of tubes in fertility. The major advantage for laparoscopic surgery is short postoperative stay duration with minimal tissue handling, less postoperative adhesions, and diminish morbidity rate. Despite of its major drawback, high-cost of robotic machine and machine maintenance; there are advantages of robotic laparoscopy compared to the conventional laparoscopy, such as improved dexterity, more precise and accurate articulation, reduced tremor, and better visualization of the operating field. In vitro fertilization (IVF) is the hallmark in the era of assisted reproductive technology and became an alternative option to regain the fertility in sterilized women. Conclusion: The pregnancy rate and live birth rate in laparoscopy, robotic and open surgery were relatively similar. Surgical reversal to women younger than 40 is recommended and laparoscopic reversal should be performed if the expertise is available. It is reasonable to counsel IVF to over 40 women. [Indones J Obstet Gynecol 2012; 36-3: 154-60] Keywords: gynecology, IVF, pregnancy outcomes, reanastomosis, robotic laparoscopy, tubal reversal
Two Designated Pathways of Ovarian Cancer and the Crucial Implications to the Treatment Putri, Henny M.A. Rachmasari
Indonesian Journal of Obstetrics and Gynecology Volume. 33. No. 4, October 2009
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To review the two designated pathways of ovarian cancer and their implications to the management of ovarian cancer. Method: Literature review Result: A proposed carcinogenesis of ovarian cancer has been developed based on a long history of pathological and molecular genetic findings. It divides ovarian cancer as having designated type I or type II pathway. Type I pathway involves ovarian carcinomas with low-grade serous subtype, mucinous, clear cell and endometrioid subtypes. They grow in a stepwise manner, shows low response toward platinum-based chemotherapy and mostly relate to MAPK pathway mutations. High-grade serous ovarian carcinomas which are often found in rapid-aggressive progression with poorer prognosis are suggested as type II pathway. Their major mutations are mainly in TP53. Optimal surgery and adjuvant chemotherapy are the treatment for both confined and advanced cancers. However, the optimal cytoreduction in type II pathway is becoming more important to increase overall survival or disease-free interval. The strategy of screening type II pathway is proposed to be shifted from detection of stage I tumors to detection of minimal ovarian carcinomas probably by biomarkers since the rapid inception is hardly found. Meanwhile the BRCA1/2 screening and classification should be improved for the hereditary breast/ovarian cancer screening. Mutations of KRAS, BRAF, PTEN and CTNNB1 occur majorly in the type I tumors. Therefore, targeted chemotherapy and inhibitor treatments which are investigated foremost in type II recurrence of ovarian malignancies may also be directed to the low response of type I pathway to platinum-based chemotherapy. Conclusion: A different strategy based on the tumorigenesis of ovarian cancer should be considered in term of screening, primary approach and following chemotherapy since there are some distinctive patterns in both pathways. [Indones J Obstet Gynecol 2009;33-4:239-46] Keywords: ovarian cancer, carcinogenesis, screening, cytoreduction, chemotherapy
Efficacy and Safety of Cryotherapy in "See and Treat" Program in Jakarta Primary Health Centre Lestari, Linda; Purwoto, Gatot; Nuranna, Laila
Indonesian Journal of Obstetrics and Gynecology Volume 4, No. 4, October 2016
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (100.393 KB) | DOI: 10.32771/inajog.v4i4.453

Abstract

Objective: To evaluate the efficacy and safety of cryotherapy in "See and Treat" program in Jakarta Primary Health Care. Method: Using descriptive cross-sectional design, data from medical records were taken with total sampling method. We took the VIA result, cryotherapy procedure, first-marriage age, number of marriage, parity, smoking habit, and the use of contraception. Data were analyzed univariately. Result: Of 86 data, the percentage of cryotherapy to change from positive to negative of VIA result was 90.70%. We did not find the progressivity to invasive cancer. Conclusion: Cryotherapy is effective to manage the cervical precancerous lesion in "See and Treat" program. [Indones J Obstet Gynecol 2016; 4-4: 227-233] Keywords: cryotherapy, Indonesia, see and treat, visual inspection of acetic acid (VIA)
Primary Prevention of Gynecologic Cancers ANDRIJONO, ANDRIJONO
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 4, October 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Pendahuluan: Terdapat tiga jenis kanker yang banyak diderita oleh wanita dalam bidang ginekologi, yaitu kanker serviks, kanker ovarium dan kanker endometrium. Patofisiologi kanker serviks hampir dikenal dengan baik, sedangkan patofisiologi kanker ovarium mulai terbuka, dan patofisiologi kanker endometrium juga mulai diketahui. Dengan dasar tersebut dilakukan penelitian terhadap faktor risiko timbulnya kanker ginekologi. Pengenalan faktor risiko yang didapat dari penelitian epidemiologi menjadi dasar untuk melakukan upaya pencegahan primer kanker ginekologi. Pencegahan primer dilakukan dengan memberikan nasihat dan terapi yang mempunyai pengaruh menurunkan risiko timbulnya kanker ginekologi. Tujuan: Menyampaikan kebijakan pencegahan primer kanker ginekologi berdasarkan hasil penelitian epidemiologi. Bahan dan cara kerja: Kajian pustaka. Hasil: Kanker serviks risikonya dapat diturunkan dengan menghindari pola pasangan ganda, menghindari merokok, mengkonsumsi makanan yang kaya vitamin C. Kanker ovarium risikonya dapat diturunkan dengan memberi kontrasepsi oral, menyusui, sterilisasi ataupun histerektomi. Kanker endometrium dapat diturunkan risikonya dengan memberikan kontrasepsi oral kombinasi, menurunkan berat badan. Kesimpulan: Dapat dilakukan upaya menurunkan risiko timbulnya kanker ginekologi melalui pencegahan primer. [Maj Obstet Ginekol Indones 2006; 30-4: 245-8] Kata kunci: pencegahan primer, kanker ginekologi
Serum Adiponectin Level is Lower in Patients with Endometriotic Cyst Anwar, Ruswana
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 3, July 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objectives: To analyse the difference of serum adiponectin level between patients with endometriotic cyst and those with non-endometriotic cyst, and its difference between endometriosis stages. Methods: This is a cross-sectional comparative analytical study involving 25 women with endometriotic cyst and 25 women with nonendometriotic cyst, which had undergone laparoscopy or laparotomy surgery. Blood samples were withdrawn and checked for serum adiponectin level in PRODIA laboratory in Jakarta. Serum adiponectin level of both groups were then measured and compared. The study was conducted in Dr. Hasan Sadikin Hospital in September- December 2012. Results: Shows no significant difference in subjects’ characteristic which are age (p = 0.994) and BMI (p = 0.267). There is a significant difference (p < 0.0001) between serum adiponectin level in endometriosis group (mean = 3.91 ± 1.976) with level of which in nonendometriosis group (mean = 8.59 ± 1.977). There is no significant difference (p = 0.384) of serum adiponectin level between stage III endometriosis (mean = 4.24 ± 1.8168) and stage IV endometriosis (mean = 3.54 ± 2.1531). Conclusion: Serum adiponectin level in patients with endometriotic cyst is significantly lower compared to level of which in patients with non-endometriotic cyst. There is no significant difference of serum adiponectin level between endometriosis stages. [Indones J Obstet Gynecol 2013; 1-3: 119-23] Keywords: adiponectin, endometriotic cyst, non-endometriotic cyst, endometriosis stage
Educational program for enhancing parental competency and outcomes of preterm infants RUSTINA, Y.; SUCHAXAYA, P.; SRISUPHAN, W.; AZWAR, A.; HARRISON, L. L.
Indonesian Journal of Obstetrics and Gynecology Volume. 30, No. 1, January 2006
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Menilai efektivitas program edukasi terhadap kompetensi orang tua dan status kesehatan bayi kurang bulan di JABOTABEK, Indonesia. Bahan dan cara kerja: Studi ini menggunakan rancangan posttest only, time series. Sebanyak 54 orang tua dan bayinya diambil secara purposif, dan dikelompokkan menjadi kelompok kontrol (n=27 pasang) dan kelompok perlakuan (n=27 pasang) dengan cara teknik menjodohkan berat badan lahir dan usia kehamilan bayi. Kelompok perlakuan mendapat program edukasi yang dikembangkan oleh peneliti berdasarkan teori pembelajaran sosial dari Bandura dan studi literatur. Kelompok kontrol mendapat asuhan konvensional. Hasil: Para Ibu dan Bapak yang berpartisipasi dalam program edukasi memperlihatkan tingkat kompetensi yang lebih tinggi pada saat bayi keluar dari rumah sakit (RS), 2 minggu, dan 6 minggu setelah bayi keluar dari RS dibandingkan dengan kelompok kontrol dengan tingkat kemaknaan (p < .05). Bayi-bayi yang orang tuanya berpartisipasi dalam program edukasi mempunyai berat badan lebih tinggi pada 2 minggu dan 6 minggu setelah keluar dari RS dibandingkan dengan bayi-bayi dari kelompok kontrol. Walaupun demikian, perbedaan tersebut tidak bermakna. Bayi-bayi dari orang tua yang berpartisipasi dalam program edukasi mempunyai frekuensi kunjungan akut yang lebih rendah pada 2 minggu dan 6 minggu setelah bayi keluar dari RS dibandingkan dengan bayi-bayi dari kelompok kontrol, tetapi perbedaan ini tidak bermakna. Tidak ditemukan adanya rawat ulang pada bayi-bayi yang orang tuanya berpartisipasi dalam program edukasi dalam 2 minggu setelah bayi keluar dari RS. Sebagai perbandingan, 7,4% bayi pada kelompok kontrol mengalami rawat ulang pada periode ini. Perbedaan ini tidak bermakna. Kesimpulan: Temuan ini mengindikasikan bahwa program edukasi dapat meningkatkan kompetensi orang tua dalam merawat bayi prematur. Terdapat kecenderungan peningkatan berat badan, penurunan kunjungan akut bayi, dan juga penurunan rawat ulang pada bayi. [Maj Obstet Ginekol Indones 2006; 30-1: 59-66] Kata kunci: bayi kurang bulan, program edukasi, kompetensi, rawat ulang. Objective: To test the effectiveness of an educational program on parental competency and outcomes of preterm infants in JABOTABEK region, Indonesia. Materid and methods: This study was a posttest only, time series design. Purposive sampling was used to recruit 54 parents and their infant who were assigned to a control group (n = 27 pairs) and an experimental group (n = 27 pairs) by matching infant’s weight and gestational age. The experimental group received an educational program deve-loped by the researcher based on Bandura’s Social Learning Theory and a review of the literature. The control group received only conventional care. Result: Mothers and fathers who participated in the educational program demonstrated higher level of competency at the time of the infant’s hospital discharge, at 2 weeks, and at 6 weeks after the infant’s discharge than those in the control group with a significant level of (p < .05). Infants of parents who participated in educational program had higher weight at 2 weeks and at 6 weeks after discharge than those in the control group. However, the differences were not significant. Infants of parents who participated in an educational program had fewer acute care visits at 2 weeks and at 6 weeks after discharge than those in the control group but, the differences were not significant. There were no hospital readmissions in infants of parents who participated in the educational program during the first 2 weeks after discharge. In comparison, 7.4% of control group infants had hospital readmissions during this period. This difference was not significant, however. Conclusion: These findings indicated that educational program could enhance parental competency in caring for their preterm infants. There was the inclination to increase infant’s weight, reduce infant’s acute care visits, and also reduce infant’s hospital readmissions. [Indones J Obstet Gynecol 2006; 30-1: 59-66] Keywords: preterm infants, educational program, competency, hospital readmission.
Gonadotoxic Effect of Combined Chemotherapy on Anti Müllerian Hormone (AMH) Level in non-Gynecologic Cancer Patients in Reproductive Age Jasirwan, Shanty Olivia F.
Indonesian Journal of Obstetrics and Gynecology Volume. 34, No. 3, July 2010
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Objective: To assess the effect of combined chemotherapy on levels of Anti-Müllerian Hormone (AMH). Method: This is a prospective cohort study on 12 non-gynecologic cancer women aged 20 - 40 years who received combined chemotherapy treatment. AMH levels and menstrual pattern before and after three months of chemotherapy were examined. The relationships between age, chemotherapy regimens and the cumulative doses on the change of AMH were also analyzed. Result: The median age of subjects was 37 years (range 20 - 40 years). Pre chemotherapy AMH analysis revealed an inverse correlation between age and AMH levels (r = -0.715; p = 0.009). AMH levels after 3 months of combined chemotherapy drastically declined to 84.6% (p = 0.002). Multivariate analysis indicated that age and total cumulative dose were the main factors contributing to the AMH levels reduction (r = -0.679; p = 0.002 and r = 0.405; p = 0.027). Ten of 12 subjects (83.3%) experienced amenorrhea after 3 months of chemotherapy and had lower level of pre and postchemotherapy AMH compared to those who still maintained normal periods (p = 0.03 and 0.02). Conclusion: AMH levels in non-gynecological cancer women who received combined chemotherapy decreased dramatically after 3 months of chemotherapy. Main factors that contribute to this were the cumulative dose and age. Most of these subjects experienced amenorrhea after 3 months of chemotherapy. [Indones J Obstet Gynecol 2010; 34-3: 119-24] Keywords: ovarian reserve, chemotherapy, Anti Müllerian Hormone (AMH), ovarian function, gonadotoxic
Efek zat aromatase inhibitor dan GnRH agonis terhadap kadar Vascular Endothelial Growth Factor-A pada kultur jaringan endometriosis AS’ADI, A.S.; HESTIANTORO, A.; ARLENI, ARLENI
Indonesian Journal of Obstetrics and Gynecology Volume. 32, No. 1, January 2008
Publisher : Indonesian Socety of Obstetrics and Gynecology

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Abstract

Tujuan: Menganalisa efek zat aromatase inhibitor, GnRH agonis dan kombinasi keduanya terhadap kadar Vascular Endothelial Growth Factor-A (VEGF-A) pada kultur jaringan endometriosis dalam lingkungan kadar steroid seks yang berbeda. Tempat: RS Fatmawati, RSUPN Dr. Cipto Mangunkusumo, Klinik Kesehatan Reproduksi Raden Saleh Jakarta dan Laboratorium MAKMAL FKUI. Rancangan/rumusan data: Penelitian eksperimental. Bahan dan cara kerja: Selama kurun waktu Juni 2006 - April 2007, terkumpul 15 sampel jaringan endometriosis dari 15 pasien endometriosis. Sampel yang didapat berasal dari dinding kista endometriosis dan dari bercak-bercak endometriosis pada genitalia interna. Semua sampel diolah sesuai protokol yang dibuat. Ada 4 sampel (27%) yang berhasil tumbuh baik dalam medium kultur. Dari 4 sampel tersebut hanya 3 sampel yang mendapat perlakuan. Masing-masing sampel dibagi ke dalam 7 well dengan jumlah sel pada masing-masing well 7,1 - 9,1 x 103 sel/ml : well 1 ditambahkan Testosteron 100 nM/L, well 2 ditambahkan Testosteron 100 nM/L dan Estradiol 10 nM/L, well 3 ditambahkan Testosteron 100 nM/L, Estradiol 10 nM/L dan Letrozol (aromatase inhibitor) 10 nM/L, well 4 ditambahkan Testosteron 100 nM/L dan Letrozol 10 nM/L, well 5 ditambahkan Testosteron 100 nM/L, Letrozol 10 nM/L dan Leuprolide asetat (GnRH agonis) 100 ng/ml, well 6 ditambahkan Testosteron 100 nM/L dan Leuprolide asetat 100 ng/ml, well 7 tanpa perlakuan (kontrol). Setelah diinkubasi selama 72 jam, supernatannya diambil dan dilakukan pemeriksaan kadar VEGF-A dengan teknik ELISA. Hasil: Nilai median kadar VEGF-A yang paling tinggi terjadi pada pemberian Testosteron + Estradiol yaitu 20,228 pg/ml dan ini lebih tinggi bila dibandingkan kontrol yang hanya 9,233 pg/ml, maupun dengan sampel yang hanya diberikan Testosteron saja yaitu 9,944 pg/ml. Nilai median kadar VEGF-A pada sediaan yang diberikan Testosteron + Estradiol yaitu 20,228 pg/ml, bila dibandingkan dengan sampel yang mendapatkan perlakuan yang sama dan ditambahkan Letrozol (aromatase inhibitor) terjadi penurunan menjadi 14,205 pg/ml. Nilai median kadar VEGF-A pada sampel yang diberikan Testosteron + Letrozol (aromatase inhibitor) 16,335 pg/ml, Testosteron + Letrozol + Leuprolide asetat (GnRH agonis) 10,653 pg/ml dan Testosteron + Leuprolide asetat 11,364 pg/ml. Nilai terendah terjadi pada sampel yang diberikan Aromatase inhibitor + GnRH agonis. Kesimpulan: Nilai median kadar VEGF-A cenderung meningkat pada sampel yang diberikan Testosteron dan Estradiol. Nilai median kadar VEGF-A cenderung lebih rendah pada sampel yang diberikan kombinasi aromatase inhibitor dan GnRH agonis. [Maj Obstet Ginekol Indones 2008; 32-1: 11-21] Kata kunci: kultur jaringan endometriosis, testosteron, estradiol, letrozol, leuprolide asetat, VEGF-A, ELISA

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