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INDONESIA
Indonesian Journal of Medicine
Published by Universitas Sebelas Maret
ISSN : -     EISSN : 25490265     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Indonesian Journal of Medicine (IJM) is an international, open-access, and double-blind peer-reviewed journal, focusing on the intersection of biomedical science, clinical medicine, and community medicine. The journal began its publication on August 20, 2015, and is published online three times yearly. It is academically designed for all physicians, health researchers, and health care professionals, regardless of their medical specialties, or type of employment.
Arjuna Subject : -
Articles 15 Documents
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Search results for , issue "Vol. 9 No. 3 (2024)" : 15 Documents clear
Effectiveness of Ethanol Extract and Ethyl Acetate Fraction of Breadfruit Leaves (Artocarpus altilis) as Antihyperglycemia Daulay, Agus Husein; Siahaan , Jekson Martiar; Syahrir, Lesmana; Tambunan, Ronald Tunggul Hotmarojahan
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.753

Abstract

Background: The rising diabetes mellitus (DM) population is a public health concern. Pharmaco­therapy for DM can cause side effects and is often inaccessible, necessitating alternative therapies like medicinal plants. Breadfruit leaves (Artocarpus altilis) have antidiabetic effects. This study aimed to examine the antihyperglycemic effect of ethanol extract and ethyl acetate fraction of bread­fruit leaves on alloxan-induced diabetic male white rats (Rattus norvegicus). Subjects and Method: This was a randomized controlled trial. Sample was 35 male white Wistar rats (Rattus norvegicus sp.) divided into 7 groups. The study was conducted at the Phytochemical Laboratory and Animal House, Faculty of Medicine, Indonesian Methodist University, from April to May 2023. The dependent variables were body weight, blood glucose levels, and diameter of the islets of Langerhans. The independent variables were variations in the dose of ethanol extract and ethyl acetate fraction of breadfruit leaves. Body weight was measured by scales. Blood glucose was measured using glucometer. Diameter of the islets of Langerhans was measured using computer-based image analysis system. Data were analyzed using Anova and Kruskal-Wallis tests. Results: Weight loss was better in the group given the ethyl acetate fraction at a dose of 200 mg/kgBW compared to the other groups. Administration of ethanol extract at a dose of 200 mg/kgBW showed a better reduction in blood glucose levels compared to the other groups, where P < 0.05 between K4 and K3, K5, and K7 on day 5. Ethanol extract at a dose of 200 mg/kgBW was able to improve the diameter of the islets of Langerhans induced by alloxan. Conclusion: A 200 mg/kg BW dose of ethyl acetate fraction reduces body weight. A 200 mg/kg BW dose of ethanol extract reduces blood glucose and improves pancreatic islet diameter.
Citicoline in Acute Ischemic Stroke: Case Report Rimbun, Surjadi; Anto, Endy Juli
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.764

Abstract

Background: Stroke is the third most common disease after heart disease and cancer and a leading cause of disability worldwide. The most common type of stroke is non-hemorrhagic stroke (SNH) or Acute Ischemic Stroke, which accounts for about 85-87% of all cases. The purpose of this case report is to examine the benefits of citicoline in a patient with SNH. Case Presentation: In this case, a 63-year-old man was admitted to the Emergency Room of the Agung Mulia Inpatient Clinic on February 25, 2023 with complaints of inability to move his right arm and leg since 5 days before entering the clinic. The complaint was felt suddenly when the patient woke up in the morning. The patient also complained of weakness and difficulty speaking and slurred speech accompanied by difficulty swallowing. The voice could still speak but was unclear but the patient understood what was being said to him. Other complaints such as headaches, nausea, vomiting, bowel and urination disorders, and fainting were denied by the patient. The patient was treated at a hospital near his house on February 21, 2023 and underwent a CT scan of the head and was treated as an outpatient. The results of the CT scan on February 21, 2023, axial section of the head without intravenous contrast, obtained the following results: Infraterritorial cerebellum and 4th ventricle appear normal, Supreterritorial hypodense lesions appear on the left lateral periventricular and in the left parietal, No midline shift, Cortical sulci and prominent ventricular system. It was concluded that the left lateral periventricular and left parietal cerebral infarction were in accordance with Non-Hemorrhagic Stroke (SNH). Senile cerebral atrophy. Based on anamnesis, physical examination, and supporting examinations. The clinical diagnosis in this case was right hemiparesis and paresis of nerves VII, IX, and X, et causa non-hemorrhagic stroke (SNH) with electrolyte disorders (Electrolyte Imbalance), given general and specific management. Results: For general management that can be given is semi-fowler position, oxygen administra­tion, administration of antihypertensive drugs and maintaining fluid and nutritional intake. While specific management with pharmacology by administering citicoline and clopidogrel is given to this patient. Conclusion: Citicoline works to prevent brain damage (neuroprotection) and helps the formation of cell membranes in the brain (neurorepair). The benefits of citicoline in this patient are seen in motor and neurological improvements based on NIHSS assessments.  
Comparison of Sleep Quality Between Acupuncture Therapy and Blue Pela Flower Tea in Adolescents: A Randomized Controlled Trial Latifah, Shafa; Prasetya, Hanung; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.765

Abstract

Background: Reduced sleep quality will have an impact such as decreased concentration, emotional disturbances, health and daily activities. There are several factors outside of puberty (hormonal) that cause the percentage of insomnia sufferers to be higher among adolescents, including lifestyle and environment which are the causes of insomnia in adolescents. Positive findings have been found in a study reporting that acupuncture and herbal butterfly pea flower tea can improve patient health and sleep quality. This study aims to determine the comparison of acupuncture therapy and herbal butterfly pea flower tea. Subjects and Method: This study is a quantitative study with a Randomized Controlled Trial (RCT) design. This study was conducted at SMKN 5 Merangin in March-April 2024. A sample of 120 students was selected using simple random sampling. The dependent variable in this study is sleep quality in cases of insomnia. The independent variables in the study are acupuncture therapy and butterfly pea herbal tea. Result: The best intervention for improving sleep quality was acupuncture (Mean= 3.65; SD= 1.12), which was better than butterfly pea tea (Mean= 2.13; SD= 1.09) or nothing (Mean= 0.20; SD= 1.20), and the difference between the groups was statistically significant (p<0.001). Conclusion: The best intervention to improve sleep quality was acupuncture compared to butterfly pea herbal tea.
Meta-Analysis of the Effect of Heavy Lifting on Low Back Pain Among Health Workers Khairunnisa; Tamtomo, Didik Gunawan; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.766

Abstract

Background: Low back pain is common in healthcare workers including doctors, nurses, midwives and physiotherapists, due to the nature of their work. These healthcare workers are often involved in tasks that involve heavy lifting. Manual patient handling, and awkward postures that are an integral part of care may have an effect on musculoskeletal injuries. This study aims to analyze the effect of heavy lifting on low back pain among healthcare workers. Subjects and Method: This study is a systematic review and meta-analysis study. The search for articles was carried out in accordance with the PICO Model eligibility criteria which include: P = Health workers, I = Heavy lifting, C = No heavy lifting, O = Low back pain. The articles used came from 2 databases, namely: PubMed and Science Direct. The keywords used were "heavy lifting" AND "low back pain" OR "musculoskeletal of low back pain” AND "healthcare professional" OR "healthcare workers". The inclusion criteria in this study included full-text articles with a cross-sectional study design, the relationship measure used was the adjusted Odds Ratio (aOR), articles published in the range 2014-2022, and the outcome was Low back pain. Articles were analyzed using the PRISMA diagram and the Review Manager 5.4.1 application. Results: 9 articles from Ethiopia, Japan, Malaysia, Nigeria, Pakistan, Saudi Arabia and Uganda. Healthcare workers who performed heavy lifting increased lower back pain by 4.36 times compared to those who did not, and the results were statistically significant (aOR=4.36; 95% CI=3.07 to 6.20; p<0.001). Conclusion: A meta-analysis of 9 cross-sectional studies concluded that heavy lifting increases low back pain in healthcare workers.
Meta-Analysis: Effect of Acupuncture Therapy on HbA1c Levels in Type II Diabetes Mellitus Wahyu, Fatimah; Prasetya, Hanung; Murti, Bhisma
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.774

Abstract

Background: Diabetes mellitus is a chronic condition that occurs when there is an increase in glucose levels in a person's blood because the body cannot produce enough of the insulin hormone, or cannot use the insulin it produces effectively. This study aims to estimate the effect of acupuncture therapy on changes in HbA1c in people with type II diabetes mellitus. Subjects and Method: This research is a systematic review and meta-analysis carried out using the PRISMA flow diagram and PICO model including Population = Type II diabetes patients; Intervention = Acupuncture Therapy; Comparison= No acupuncture therapy or sham acupuncture; Outcome= Change in HbA1c and quality of life. Article searches through journal databases include: PubMed, Science Direct, Google Scholar, Springer Link, BMC and Hindawi. Search keywords: acupuncture, AND "type 2 diabetes mellitus", "acupuncture for diabetes mellitus type 2" AND HbA1c OR "quality of life" AND "randomized controlled trial". Inclusion criteria are full paper articles, Randomized Controlled Trial (RCT) research. The measure of relationship used is Mean SD. Eligible articles were analyzed using the Revman 5.3 application. Results: Randomized Controlled Trial (RCT) from China, England, Iran, Egypt and Taiwan. Acupuncture therapy can reduce HbA1c in type II diabetes mellitus patients by 0.57 units higher than in controls (SMD -0.57; 95% CI= -1.15 to 0.02; p=0.060). Acupuncture therapy improved the quality of life in type II diabetes mellitus patients by 0.87 units compared to controls (SMD 0.87; 95% CI= 0.00 to 1.74; p=0.050). Conclusion: Acupuncture therapy is effective in reducing HbA1c levels and improving quality of life in patients with type II diabetes mellitus.

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