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Effectiveness of Ethanol Extract and Ethyl Acetate Fraction of Breadfruit Leaves (Artocarpus altilis) as Antihyperglycemia Daulay, Agus Husein; Siahaan , Jekson Martiar; Syahrir, Lesmana; Tambunan, Ronald Tunggul Hotmarojahan
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.753

Background: The rising diabetes mellitus (DM) population is a public health concern. Pharmacotherapy for DM can cause side effects and is often inaccessible, necessitating alternative therapies like medicinal plants. Breadfruit leaves (Artocarpus altilis) have antidiabetic effects. This study aimed to examine the antihyperglycemic effect of ethanol extract and ethyl acetate fraction of breadfruit leaves on alloxan-induced diabetic male white rats (Rattus norvegicus). Subjects and Method: This was a randomized controlled trial. Sample was 35 male white Wistar rats (Rattus norvegicus sp.) divided into 7 groups. The study was conducted at the Phytochemical Laboratory and Animal House, Faculty of Medicine, Indonesian Methodist University, from April to May 2023. The dependent variables were body weight, blood glucose levels, and diameter of the islets of Langerhans. The independent variables were variations in the dose of ethanol extract and ethyl acetate fraction of breadfruit leaves. Body weight was measured by scales. Blood glucose was measured using glucometer. Diameter of the islets of Langerhans was measured using computer-based image analysis system. Data were analyzed using Anova and Kruskal-Wallis tests. Results: Weight loss was better in the group given the ethyl acetate fraction at a dose of 200 mg/kgBW compared to the other groups. Administration of ethanol extract at a dose of 200 mg/kgBW showed a better reduction in blood glucose levels compared to the other groups, where P < 0.05 between K4 and K3, K5, and K7 on day 5. Ethanol extract at a dose of 200 mg/kgBW was able to improve the diameter of the islets of Langerhans induced by alloxan. Conclusion: A 200 mg/kg BW dose of ethyl acetate fraction reduces body weight. A 200 mg/kg BW dose of ethanol extract reduces blood glucose and improves pancreatic islet diameter.

PENYULUHAN PENCEGAHAN STUNTING PADA ANAK DI SD NEGERI 060919 Tarigan, Juliyanti; Syahrir, Lesmana; Tiji, Wijaya Taufik; Simangunsong, Batara; Pasaribu, Sumihar M.R.; Gea, Melfan J.; Harianja, Ester G.; Tampubolon, Gelberd V.M.; Simalango, Penina T.; Ginting, Lucky A.B.; Sibuea, Charina T.Y.; Pangaribuan, Megaria Evhiphanias; Simanullang, Yolanda K.H.R.; Ginting, Mischkel A.; Meha, Panahian M.
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp208-211

Stunting is a situation where a child's height is stunted compared to the height of children his age. In Indonesia, stunting is a problem in the health sector that is still high. This condition occurs because children are malnourished for a long time with signs of failure in the child's growth and development (growth faltering) which starts from pregnancy until the child is 2 years old. This is the formulation of our problem in holding outreach activities on the topic of Stunting at SD Negeri 060919, Kec. Medan Sunggal, Medan city. This article was created with the aim of providing education and information regarding stunting prevention. Thus, this activity is very useful in providing information about how to prevent and reduce the incidence of stunting. It is hoped that this activity will be carried out at SD Negeri 060919, Kec. Medan Sunggal, Medan City to pay more attention to the nutritional intake of mothers and children, so that the incidence of stunting in Indonesia is reduced.

PENYULUHAN PENCEGAHAN STUNTING PADA ANAK DI SD NEGERI 060919 Tarigan, Juliyanti; Syahrir, Lesmana; Tiji, Wijaya Taufik; Simangunsong, Batara; Pasaribu, Sumihar M.R.; Gea, Melfan J.; Harianja, Ester G.; Tampubolon, Gelberd V.M.; Simalango, Penina T.; Ginting, Lucky A.B.; Sibuea, Charina T.Y.; Pangaribuan, Megaria Evhiphanias; Simanullang, Yolanda K.H.R.; Ginting, Mischkel A.; Meha, Panahian M.
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 2 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No2.pp208-211

Stunting is a situation where a child's height is stunted compared to the height of children his age. In Indonesia, stunting is a problem in the health sector that is still high. This condition occurs because children are malnourished for a long time with signs of failure in the child's growth and development (growth faltering) which starts from pregnancy until the child is 2 years old. This is the formulation of our problem in holding outreach activities on the topic of Stunting at SD Negeri 060919, Kec. Medan Sunggal, Medan city. This article was created with the aim of providing education and information regarding stunting prevention. Thus, this activity is very useful in providing information about how to prevent and reduce the incidence of stunting. It is hoped that this activity will be carried out at SD Negeri 060919, Kec. Medan Sunggal, Medan City to pay more attention to the nutritional intake of mothers and children, so that the incidence of stunting in Indonesia is reduced.

Hubungan Gaya belajar, Motivasi, dan Penyesuian diri Hasil Prestasi Belajar Mahasiswa Kedokteran Silaban, Elfrida Megawaty; RVO, Ivonne; Syahrir, Lesmana
Jurnal Kedokteran Methodist Vol. 15 No. 2 (2022): Jurnal Kedokteran Methodist
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: Education Faculty of Medicine in Indonesia has the aim of educating students with a learning process to complete their education. To see the success of learning from students, it is seen from the cumulative achievement index (GPA) which is a reflection of the results achieved from learning from the beginning of the semester to the end. Factors that can affect learning outcomes are learning styles, motivation and self-adjustment. Objective: To determine the relationship between learning styles, motivation, and self-adjustment to the learning achievement of medical students at HKBP Nommensen University. Method : This research is a quantitative research that uses a cross sectional. The number of samples is 62 respondents. Sampling was done by purposive sampling. The research was conducted at the Faculty of Medicine HKBP Nommensen Stambuk 2018 using the google form. Data presentation includes univariate and bivariate analysis using Pearson Correlation. Result : The results of bivariate analysis showed that there was a positive relationship between learning style and learning achievement (p-value= 0.006), there was a positive relationship between motivation and learning achievement (p-value <0.05), and there was a positive relationship between self-adjustment to learning achievement outcomes (p-value <0.05). Conclusion: Based on this research, it can be concluded that the variables of learning style, motivation, and self-adjustment have a significant and positive relationship to the learning achievement of medical students at HKBP Nommensen Stambuk 2018.

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