Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Oto Rhino Laryngologica Indonesiana

orli
Website

Published by Perhimpunan Dokter Spesialis Telinga Hidung dan Tenggorok Bedah Kepala Leher Indonesia

ISSN : 02163667 EISSN : 25983970 DOI : -

Core Subject : Health,

Health Professions Medicine & Pharmacology

Journal Othorhinolaryngologica Indonesiana is a peer-reviewed and open access journal that focuses on promoting otorhinolaryngology-head and neck surgery that publishes research reports, case reports, and literature reviews, to increase knowledge and updating diagnostics procedurs on otorhinolaryngology-head and neck surgery.

Arjuna Subject : -

Articles 481 Documents

1 2 3 4 5

Hubungan frekuensi dan intensitas tinitus subjektif dengan kualitas hidup pasien Dimas Adi Nugroho; Muyassaroh Muyassaroh; Zulfikar Naftali
Oto Rhino Laryngologica Indonesiana Vol 45, No 1 (2015): Volume 45, No. 1 January - June 2015
Publisher : PERHATI-KL

Latar belakang: Tinitus subjektif menimbulkan stres, depresi, kecemasan, dan penurunan kualitashidup. Frekuensi dan intensitas tinitus dilaporkan berhubungan dengan beratnya gangguan pada pasien.Hubungan frekuensi dan intensitas tinitus dengan kualitas hidup pasien menggunakan kuisioner TinnitusHandicap Inventory (THI) belum pernah dilaporkan di Indonesia. Tujuan: Menganalisis hubunganfrekuensi dan intensitas tinitus subjektif dengan kualitas hidup pasien. Metode: Desain penelitian potonglintang . Sampel penelitian adalah pasien tinitus subjektif yang datang ke klinik THT-KL RSUP Dr. Kariadi.Frekuensi dan intensitas tinitus diperiksa pitch-matching dan loudness-matching dengan audiometernada murni. Kualitas hidup dinilai menggunakan skor THI. Analisis data dengan uji korelasi. Hasil:Subjek penelitian sebanyak 31 pasien, laki-laki 15 orang (48,4%) dan perempuan 16 orang (51,6%),dengan rentang umur 25-60 tahun. Pasien dengan pendengaran normal sebanyak 18 orang (58,1%) dankurang pendengaran sebanyak 13 orang (41,9%). Gangguan kualitas hidup pasien terbanyak didapatkangangguan sedang, sebanyak 12 (38,7%). Frekuensi tinitus berhubungan dengan kualitas hidup pasien(p=0,005) dengan tingkat korelasi sedang (r=0,491). Intensitas tinitus berhubungan dengan kualitas hiduppasien (p=0,043) dengan tingkat korelasi lemah (r=0,365). Kesimpulan: Frekuensi dan intensitas tinitusberhubungan dengan kualitas hidup pasien. Kata kunci: tinitus subjektif, kualitas hidup, Tinnitus Handicap InventoryABSTRACT Background: Subjective tinnitus causes stress, depression, anxiety, and decrease quality of life. Thefrequency and intensity of tinnitus has been reported to have correlation with patients discomfort.Correlation between frequency and intensity of tinnitus with quality of life using Tinnitus HandicapInventory (THI) questionnaires has never been reported in Indonesia. Objective: To analize correlationbetween frequency and intensity of subjective tinnitus with quality of life. Method: Cross sectionalstudy was used in this research. Samples of the study were subjective tinnitus patients who attendedOtolaryngologic clinic Kariadi Hospital. Frequency and intensity of tinnitus was examined by pitchloudnessmatching using pure tone audiometry. Quality of life was assessed by THI scores. Correlationtest used to analize the data. Results: Subject of the study were 31 patients, consisted of 15 (48,4%)males and 16 (51,6%) females, age range between 25-60 years old. Eighteen (58,1%) patients had normalhearing and 13 (41,9%) with hearing loss. The highest disturbance of quality of life obtained in patientswas moderate handicap in 12 (38,7%) patients. Correlation between frequency of tinnitus with qualityof life was statistically significant (p=0,005) with moderate level of correlation (r=0,491). Correlationbetween intensity of tinnitus with quality of life was statistically significant (p=0,043) with weak level ofcorrelation (r=0,365). Conclusion: Frequency and intensity of subjective tinnitus had correlation withquality of life. Keywords: subjective tinnitus, quality of life, Tinnitus Handicap Inventory

Perbedaan transpor mukosiliar pada pemberian larutan garam hipertonik dan isotonik penderita rinosinusitis kronis Sarwastuti Hendradewi; Novi Primadewi; Nurmala Shofiyati
Oto Rhino Laryngologica Indonesiana Vol 46, No 2 (2016): Volume 46, No. 2 July - December 2016
Publisher : PERHATI-KL

Latar belakang: Rinosinusitis kronis (RSK) merupakan inflamasi mukosa hidung dan sinus paranasal dengan jangka waktu gejala 12 minggu atau lebih. Transpor mukosiliar merupakan suatu mekanisme pertahanan lokal pada hidung dan sinus paranasal. Pada RSK terjadi disfungsi transpor mukosiliar. Tujuan: Mengetahui perbedaan transpor mukosiliar pada pemberian larutan garam hipertonik dan isotonik pada penderita RSK. Metode: Penelitian eksperimental murni dengan desain uji klinis randomisasi. Sampel terdiri dari dua kelompok, yaitu RSK yang mendapat larutan garam isotonik dan RSK yang mendapat larutan garam hipertonik. Tiap kelompok terdiri dari 25 sampel. Waktu transpor mukosiliar dilakukan pra dan pasca terapi memakai uji sakarin. Hasil: Secara keseluruhan, selama dua minggu masa terapi, didapati penurunan waktu transpor mukosiliar pada kelompok pasien yang diberi larutan garam hipertonik (13,00±2,12 menit) lebih besar dibandingkan pada kelompok pasien yang diberi larutan garam isotonik (6,84±2,54 menit) dan secara statistik terdapat perbedaan yang signifikan (p<0,001). Kesimpulan: Pemberian larutan garam hipertonik dapat menurunkan waktu transpor mukosiliar lebih besar dibandingkan larutan garam isotonik pada penderita rinosinusitis kronis.Kata kunci: Transpor mukosiliar, larutan garam isotonik, larutan garam hipertonik, rinosinusitis kronis ABSTRACT Background: Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinuses mucosa with periods of symptoms 12 weeks or more. Mucociliary transport plays a role as local defense mechanism of the nasal and paranasal sinuses. In CRS, there are dysfunctions on the mucociliary transport. Purpose: This study aimed to find out the difference of mucociliary transport after nasal washing with hypertonic and isotonic saline solutions in patients with CRS. Methods: This was a pure experimental study with randomized controlled trial designs. The sample was divided into 2 groups: CRS with isotonic saline solution and CRS with hypertonic saline solution treatment. Each group was consisted of twenty five samples. The mucociliary transport time examination were performed pre and post treatment by using saccharin test. Result: During the 2 weeks of therapy, the overall of mucociliary transport time reduction in the group of patients given hypertonic saline solution (13.00±2.12 minutes) were bigger than in the group of patients who were given isotonic saline solution (6.84±2.54 minutes) and there was a significant difference statistically (p<0.001). Conclusion: Hypertonic saline solution is better than isotonic saline solution in reducing mucociliary transport time.Keywords: Mucociliary transport, isotonic saline solution, hypertonic saline solution, chronic rhinosinusitis

Patogenesis dan diagnosis gangguan napas saat tidur dengan Drug Induce Sleep Endoscopy (DISE) Elvie Zulka Kautzia Rachmawati; Wresty Arief; Susyana Tamin; Rahmanofa Yunizaf; Fauziah Fardizza
Oto Rhino Laryngologica Indonesiana Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017
Publisher : PERHATI-KL

Latar belakang: Obstructive sleep apnea (OSA) ialah penyakit kronis yang terjadi akibat episode intermiten sumbatan jalan napas komplit atau sebagian saat tidur. OSA dapat menimbulkan komplikasi seperti hipertensi, diabetes melitus, stroke dan excessive daytime sleepiness yang dapat berakibat fatal. OSA merupakan bagian dari gangguan napas saat tidur. Tujuan: Mengindentifikasi letak atau level dan konfigurasi sumbatan pada saat tidur. Tinjauan pustaka: Cara untuk mendiagnosis OSA adalah nasofaringolaringoskopi dengan Muller`s maneuver, pemeriksaan polisomnography (PSG), dan drug induce sleep endoscopy (DISE). Pemeriksaan PSG merupakan standar baku emas untuk mendapakan nilai apnea-hipopnea index (AHI) yang menentukan derajat OSA. Pemeriksaan untuk mengidentifikasi lokasi sumbatan jalan napas yang menyebabkan peningkatan resistensi aliran udara adalah Muller`s maneuver dan DISE. Pada pemeriksaan DISE, digunakan propofol atau midazolam secara intravena untuk menstimulasi keadaan sumbatan pada saat tidur, dilanjutkan dengan pemeriksaan nasofaringolaringoskopi. Kesimpulan: Pemeriksaan ini merupakan cara yang sangat terpercaya untuk menentukan level sumbatan pada keadaan tidur, sehingga jenis tindakan operasi yang dilakukan menjadi lebih tepat. Kata kunci: Drug induced sleep endoscopy, midazolam, propofol, manuver Muller’s, obstructive sleep apnea, polisomnografi ABSTRACT Background: Obstructive sleep apnea (OSA) is a common chronic disorder caused by intermittent episodes of complete or partial upper airway obstruction during sleep. It may lead to complications such as hypertension, diabetes mellitus, stroke, as well as excessive daytime sleepiness which can be fatal. OSA is a part of sleep disorder breathing. Purpose: To identify the sites or the levels of obstruction and its configuration. Literature review: Muller’s maneuver upon nasopharyngoscopy, polysomnography (PSG), and drug-induced sleep endoscopy (DISE) are the modalities for diagnosing OSA. Polysomnography is the gold standard examination for OSA, one of the variables; the apnea-hipopnea index (AHI) is used to determine the presence and severity of OSA. Muller’s maneuver and DISE are the examination to identify the sites responsible for increase in airflow resistance. DISE technique uses intravena injection of propofol or midazolam to produce obstruction in a “natural sleep” condition followed by nasopharyngolaryngoscopy examination. Conclusion: DISE is considered as a very reliable means to define the level of obstruction during sleeping, thus could help to determine appropriate surgery. Keywords: Drug induced sleep endoscopy, midazolam, propofol, Muller’s maneuver, obstructive sleep apnea, polisomnography

Hubungan otitis media supuratif kronis disertai kolesteatom dengan gangguan pengecapan Lusiana Herawati Yammin; Joseph Bambang Soemantri; Lukmantya -
Oto Rhino Laryngologica Indonesiana Vol 43, No 1 (2013): Volume 43, No. 1 January - June 2013
Publisher : PERHATI-KL

Background: Chorda tympanic nerve runs through the middle ear between the long crus of the incus andmanubrium of the mallei. Chorda tympanic nerve supplies the front two-thirds of the tongue taste. Many studieshad reported about gustatory alteration caused by ear surgery, but there were only small numbers of study aboutthis alteration in chronic otitis media (COM) patients prior to surgical treatment. Purpose: To find out whether theCOM patient with cholesteatoma have taste alteration or not, to investigate the relationship between COM withcholesteatoma (cholesteatoma level) to gustatory disorder (gustatory level) and the taste alteration in COMpatients with cholesteatoma before and after mastoidectomy surgery. Method: This was an analytic observationalstudy with cross sectional design. Sampling method was accidental sampling that involved 18 patients. Gustatoryfunction before and after surgery was examined using a taste strip test. Statistical analysis used in this study wasSpearman correlation test and Repeated ANOVA test. Results: Subjectively there was no taste disorder complaintamong these patients, although objectively there were patients that had taste disorder. The highest taste disordersfound in this study was hipogeusia (55,56%) followed by ageusia (22,22%) and normal taste (22,22%). Spearmancorrelation test between COM with cholesteatoma (cholesteatoma level) to gustatory disorder (gustatory level) wasp<0,05 and r=-0,543. Repeated ANOVA test taste alteration in COM patients with cholesteatoma before and aftermastoidectomy surgery was p >0,05. Conclusion: Most of COM patients with cholesteatoma had alteration of tasteprior to surgery. There was significant correlation between cholesteatoma level to gustatory disorder and thehigher cholesteatoma level,the lower the gustatory level. Statistically there was no significant differences gustatoryfunction in COM patients with cholesteatoma before and after surgery.Keywords: COM patient with cholesteatoma, gustatory, surgery. ABSTRAKLatar belakang: Nervus korda timpani berjalan melalui telinga tengah di antara prosesus longus inkus danmanubrium malei. Nervus korda timpani mempersarafi pengecapan dua pertiga depan lidah. Banyak penelitian tentangperubahan pengecapan akibat operasi telinga tengah, tetapi sedikit penelitian tentang perubahan pengecapan padapenderita otitis media supuratif kronis (OMSK) sebelum operasi. Tujuan: Mengetahui ada tidaknya penderita OMSKdengan kolesteatom yang mengalami gangguan pengecapan, adanya hubungan antara OMSK dengan kolesteatom(tingkat kolesteatom), gangguan pengecapan (tingkat pengecapan) dan ada tidaknya perubahan pengecapan padapenderita OMSK dengan kolesteatom sebelum dan setelah operasi mastoidektomi. Metode: Penelitian merupakanpenelitian observasional analitik dengan pendekatan cross sectional. Pengambilan sampel menggunakan teknikaccidental sampling melibatkan 18 penderita OMSK dengan kolesteatom. Pemeriksaan fungsi pengecapan dilakukansebelum dan setelah operasi menggunakan tes strip pengecapan. Analisis statistik menggunakan uji korelasi Spearmandan uji Repeated ANOVA. Hasil: Penderita OMSK dengan kolesteatom secara subjektif tidak mempunyai keluhanperubahan pengecapan, meskipun secara objektif penderita ada yang mengalami gangguan pengecapan. Hipogeusiamenempati proporsi terbanyak (55,56%) diikuti oleh ageusia (22,22%) dan pengecapan normal (22,22%). Hasil ujikorelasi Spearman antara OMSK dengan kolesteatom (tingkat kolesteatom) terhadap gangguan pengecapan (tingkatpengecapan) yaitu p < 0,05 dan r = -0,543. Hasil uji Repeated ANOVA pengecapan penderita OMSK dengankolesteatom sebelum dan setelah operasi mastoidektomi yaitu p>0,05. Kesimpulan: Sebagian besar penderita OMSKdengan kolesteatom telah mengalami penurunan pengecapan. Didapatkan hubungan bermakna antara tingkatkolesteatom dan tingkat (gangguan) pengecapan. Semakin tinggi tingkat kolesteatom pada penderita OMSK semakinmenurun tingkat pengecapan. Secara statistik tidak ada perbedaan bermakna perubahan pengecapan penderita sebelumdan setelah operasi.Kata kunci: OMSK dengan kolesteatom, pengecapan, operasi.

Hubungan jenis bakteri aerob dengan risiko tuli sensorineural penderita otitis media supuratif kronis Dyah Prathiwi Wahyudiasih; Edi Handoko; Endang Retnoningsih
Oto Rhino Laryngologica Indonesiana Vol 41, No 2 (2011): Volume 41, No. 2 July - December 2011
Publisher : PERHATI-KL

Background: Sensorineural hearing loss (SNHL) as sequelae of chronic supurative otitis media(CSOM) is still debatable. Previous researches had shown the role of bacterial toxin upon the roundwindow membrane which could induce SNHL. Purpose: To find the relationship between the kind ofaerobic bacteria with the risk of SNHL in CSOM patients. Method: This study used cross sectional 2005 toDecember 31design and involved 45 CSOM patients with SNHL in Dr. Saiful Anwar hospital from January 1, 2010. The specimen for microbacterial cultures and sensitivity tests were taken from themastoid antrum during mastoidectomy. Statistical analysis employed Spearman correlation test, t-test,and Mann Whitney. Result: The mean values of bone conduction threshold (BCT) in all of CSOM cases,especially in dangerous type CSOM patients, with bacteria culture showed Staphylococcus aureus werehigher than others bacteria (p<0.05). Conclusion: There was significant relationship between the kindof aerobic bacteria with the BCT averages in CSOM patients, especially dangerous type CSOM patients.s Keywords: CSOM, SNHL, aerobic bacteria, toxin, bone conduction threshold Abstrak : Latar belakang: Tuli sensorineural yang disebabkan oleh otitis media supuratif kronis (OMSK)mekanismenya belum diketahui secara pasti. Beberapa penelitian telah menunjukkan peran toksin bakterimerusak telinga dalam, sehingga menyebabkan tuli sensorineural. Tujuan: Mengetahui hubungan antarajenis bakteri aerob dengan risiko tuli sensorineural penderita OMSK. Metode: Penelitian ini menggunakandesain cross sectional dengan melibatkan 45 penderita OMSK yang disertai tuli sensorineural di RSUDDr. Saiful Anwar Malang, pada periode 1 Januari 2005-31 Desember 2010. Kultur bakteri diambil dariswab antrum mastoid saat operasi mastoidektomi. Analisis statistik yang digunakan adalah uji Spearman,uji t dan Mann Whitney. Hasil: Rerata ambang hantaran tulang cenderung lebih tinggipadapenderitadengan hasil kultur Staphylococcus aureus dibanding jenis bakteri lainnya. Hal ini berlaku pada penderitaOMSK keseluruhan dan OMSK tipe maligna saja (p>0,05). Kesimpulan: Terdapat hubungan bermaknaantara jenis bakteri aerob dengan rerata ambang hantaran tulang penderita OMSK, khususnya OMSKtipe maligna. Kata kunci: OMSK, tuli sensorineural, bakteri aerob, toksin, ambang hantaran tulang

Efektivitas Pelargonium sidoides terhadap penurunan gejala rinosinusitis kronik alergi tanpa polip disertai gangguan tidur Ahmad Juwaeni; Teti Madiadipoera; Iwin Soemarman; Sinta Sari Ratunanda
Oto Rhino Laryngologica Indonesiana Vol 44, No 1 (2014): Volume 44, No. 1 January - June 2014
Publisher : PERHATI-KL

Latar Belakang: Rinosinusitis kronik tanpa polip adalah inflamasi mukosa hidung dan sinus paranasal lebih dari 12 minggu. Etiologinya multifaktorial, terbanyak alergi. Gejala utamanya kongesti hidung, hidung berair, nyeri wajah, gangguan penciuman, dan menyebabkan gangguan tidur. Gangguan tidur disebabkan kongesti hidung dan peningkatan mediator inflamasi IL-1, IL-6, dan TNF-α. Tujuan: Membuktikan efektivitas terapi adjuvan rinosinusitis kronik alergi tanpa polip disertai gangguan tidur menggunakan ekstrak Pelargonium sidoides. Perbaikan gejala dan tanda klinis, serta penurunan kadar IL-1, IL-6, dan TNF- α sekret hidung sebagai indikator. Metode: Quasi-experimental open labelledpre and posttest design pada 20 sampel, dibagi menjadi dua kelompok. Kelompok pertama diterapi larutan cuci hidung NaCl isotonis, semprot hidung kortikosteroid dan ekstrak Pelargonium sidoides. Kelompok kedua (kontrol) tidak diberikan ekstrak Pelargonium sidoides. Gejala klinis dinilai dengan Total Nasal Score Symptoms (TNSS), Visual Analog Scale (VAS), dan nasoendoskopi. Kualitas hidup dengan Rhinoconjuntivitis Quality of Life Questionnaires (RQLQ), dan Sinonasal Outcame Test-20 (SNOT-20). Hasil: Penurunan skor Total Nasal Score Symptoms (TNSS) (p=0,001), Visual Analog Scale (VAS) hidung tersumbat (p=0.018), VAS hidung berair (p=0,02), VAS nyeri wajah (p=0,008),skor nasoendoskopi (p=0,03), dan Rhinoconjuntivitis Quality of Life Questionnaires (RQLQ) activity (p=0,003), sleep (p=0,001), non-nose/eye symptoms (p=0,005), dan emotional (p=0,01) pada kelompok perlakuan berbeda bermakna dibandingkan kelompok kontrol berdasarkan uji Mann-Whitney. Tidak ada perbedaan bermakna pada skor SNOT-20 (p=0,096), penurunan kadar IL-1 (p=0,529), IL-6 (p=0,529), dan TNF-α (p=0,971). Kesimpulan: ekstrak Pelargonium sidoides secara klinis efektif sebagai terapiadjuvan rinosinusitis kronik alergi tanpa polip disertai gangguan tidur, namun tidak didukung penurunan kadar IL-1, IL-6, dan TNF-α sekret hidung. Kata kunci: gangguan tidur, IL-1, IL-6, TNF-α, Pelargonium sidoides, rinosinusitis kronik alergi tanpa polip. ABSTRACTBackground: Chronic rhinosinusitis without nasal polyps is inflammation of the nasal and paranasal sinus mucosa that lasts more than 12 weeks. It has multifactorial etiologies, and allergy is the most common. Its main symptoms are nasal congestion, runny nose, facial pain, smell disturbance, and can cause sleep disturbances. Sleep disturbances caused by nasal congestion and increased of inflammatory mediators IL-1, IL-6, and TNF-α. Purpose: To prove effectiveness of Pelargonium sidoides extract as adjuvant therapy in allergic chronic rhinosinusitis without nasal polyps accompanied by sleep disturbances. The indicators are improvement of clinical signs and symptom, and decreased level of IL-1, IL-6, and TNF-α nasal secretions. Methods: Quasi-experimental design with 20 samples, dividedinto two groups. First group treated with isotonic nasal saline solution, corticosteroid nasal spray, and extract of Pelargonium sidoides. Second group (control) were not given extract of Pelargonium sidoides. Clinical symptoms were measured with TNSS, VAS, and nasoendoscopy. Qualityof Life measured by RQLQ and SNOT-20. Results: TNSS (p= 0.001), nasoendoscopy score, VAS nasal congestion (p=0,018), rinorrhea (p=0,02) facial pain (0,008), and improving RQLQ activity (p= 0.003), sleep (p=0.001), non-nose/eye symptoms (p=0,005), and emotional (p=0,01) in the treated group significanly difference compare to the control group based on Mann-Whitney tes. No significant difference in SNOT-20 score , and decreased levels of IL-1, IL-6, and TNF-α. Conclusion: Pelargonium sidoides extract can be used as adjuvant therapy of chronic allergic rhinosinusitis without nasal polyps with sleep disturbance, but not supported by decrease of IL-1, IL-6, and TNF-α.nasal secretion.Keywords: IL-1, IL-6, TNF-α, Pelargonium sidoides, allergic chronic rhinosinusitis without nasal polyps, sleep disturbance.

Kajian faktor-faktor yang berhubungan dengan skor nasalance pada pasien celah palatum Duhita Yassi; Dini Widiarni; Tri Juda Airlangga; Lestaria Aryanti; Muchtarudin Mansyur
Oto Rhino Laryngologica Indonesiana Vol 45, No 2 (2015): Volume 45, No. 2 July - December 2015
Publisher : PERHATI-KL

Latar belakang: Celah bibir dan palatum merupakan kelainan proses pertumbuhan area orofasial yang menimbulkan permasalahan kompleks. Penelitian ini menitikberatkan permasalahanyang terkait dengan fungsi bicara. Tujuan: Penelitian ini melaporkan gambaran skor nasalance padacelah palatum, hubungan antara skor nasalance percontoh celah palatum dan tanpa celah palatum sertafaktor-faktor yang berhubungan dengan skor nasalance. Metode: Desain penelitian adalah comparativecross sectional. Pengambilan percontoh dilakukan dengan purposive sampling. Dilakukan wawancara,pengisian kuesioner, pemeriksaan THT, audiometri, timpanometri, nasoendoskopi, dan nasometri.Hasil: Didapatkan gambaran rerata skor nasalance percontoh celah palatum. Terdapat perbedaanbermakna antara skor nasalance percontoh celah palatum dan tanpa celah palatum pada Uji Gajah danUji Hantu (p<0,001). Pada analisis multivariat secara keseluruhan faktor-faktor yang berhubungandengan skor nasalance (adenoid, otitis media efusi, serta gangguan pendengaran) dan keberadaancelah palatum berpengaruh secara signifikan terhadap skor nasalance untuk semua uji nasalance(p<0,05) pada pengujian terhadap kedua kelompok percontoh. Bila dilihat secara parsial faktor adenoidberpengaruh secara signifikan terhadap skor semua uji nasalance baik pada analisis kedua kelompokpercontoh maupun pada percontoh celah palatum saja. Kesimpulan: Rerata skor nasalance kelompokcelah palatum lebih tinggi daripada kelompok tanpa celah palatum. Didapatkan peran faktor yangberpengaruh terhadap skor nasalance, khususnya adenoid. Diperlukan penelitian lebih lanjut terhadappercontoh sesudah operasi sehingga bisa dijadikan sebagai evaluasi terhadap keberhasilan tindakan. Kata kunci: celah palatum, skor nasalance, tonsil, adenoid, otitis media efusi, gangguan pendengaran ABSTRACTBackground: Cleft lip and palate is an orofacial malformation and associated with many problems. This study concerned in speech problem in cleft palate patients. Purpose: This study reportednasalance score in cleft palate patients, the correlation between nasalance score in cleft palate and noncleft palate groups and also some factors related with nasalance score in cleft palate patients. Methods:The design of this study was comparative cross sectional, with purposive sampling. Data was collectedwith interview, questioner apllication, ENT examination, audiometry, tympanometry, nasoendoscopy,and nasometry. Results: The result of this study reported the mean of nasalance score in cleft palatepatients. There was significant difference in nasalance score between cleft palate and non cleft palatepatients in Uji Gajah and Uji Hantu (p>0,05). In multivariate analysis, in general the factors relatedwith nasalance score (adenoid, otitis media with effusion, and hearing loss) and cleft palate itself weresignificantly correlated with nasalance score in all nasalance test (p<0,05) in both groups analysis butno signifficant correlation in cleft palate group analysis. Partially, adenoid was significantly correlated in both group analysis and cleft palate group analysis. Conclusion: The mean of nasalance score incleft palate group was higher than non cleft group. Some factors in this study, especially adenoid had corelations with nasalance score. It needs further study to evaluate the nasalance score patients withcleft palate after surgery to compare the results. Keywords: cleft palate, nasalance score, tonsil, adenoid, otitis media with effusion, hearing disturbance

Pengaruh cuci hidung terhadap gejala, transpor mukosiliar, dan eosinofil hidung pada pekerja pabrik kayu Ayu Citra Resmi; Riece Hariyati; Anna Mailasari Kusuma Dewi
Oto Rhino Laryngologica Indonesiana Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017
Publisher : PERHATI-KL

Latar belakang: Bekerja di lingkungan dengan debu kayu menyebabkan inhalasi partikel melaluisaluran pernapasan termasuk hidung. Pajanan debu kayu dapat menimbulkan keluhan di hidung, gangguantranspor mukosiliar hidung (TMSH), dan reaksi inflamasi di mukosa rongga hidung. Cuci hidung NaCl0,9% dianggap dapat mengurangi gejala, memperbaiki TMSH, dan mengurangi mediator inflamasi dimukosa rongga hidung.Tujuan: Membuktikan pengaruh cuci hidung NaCl 0,9% terhadap perbaikan skorgejala, waktu TMSH, dan jumlah eosinofil hidung.Metode: Penelitian intervensi, uji acak terkendali disebuah pabrik kayu pada bulan Januari – Maret 2016. Sampel pekerja yang telah memenuhi kriteria inklusidan eksklusi, kemudian dihitung skor gejala hidung menggunakan SNOT20, waktu TMSH dan jumlaheosinofil hidung. Kelompok perlakuan diberi cuci hidung NaCl 0,9% sebanyak 2 kali per hari dan selalumenggunakan masker. Kelompok kontrol memakai masker saja. Perlakuan diberikan selama 2 minggu,setelah itu dihitung kembali skor gejala SNOT 20, waktu TMSH, dan jumlah eosinofil hidung.Hasil:Didapati subyek penelitian sebanyak 36 orang pekerja pabrik kayu, 18 sampel diberi perlakuan dan 18sampel kontrol. Skor gejala hidung dan waktu TMSH setelah perlakuan, lebih baik dibanding kontrol(p<0,05). Jumlah eosinofil hidung setelah perlakuan tidak lebih rendah dibanding kontrol (p=0,324).Kesimpulan: Cuci hidung NaCl 0,9% terbukti berpengaruh terhadap perbaikan skor gejala hidung danwaktu TMSH, tetapi tidak berpengaruh terhadap jumlah eosinofil hidung.Kata kunci: Debu kayu, transpor mukosiliar, SNOT20, eosinofil, cuci hidung, NaCl 0,9% ABSTRACTBackground: Working in wood dust exposure causes particle inhalation through respiratory system,including the nose. It promotes nasal symptoms, nasal mucocilliary transport (NMCT) disfunction, andinflamatory response of nasal mucosa. Nasal saline irrigation 0.9% is considered to decrease symptoms,restore nose mucocilliary transport, and decrease inflamatory mediator in nasal mucosa hence workingcaused-diseases. Purpose: To find out the effect of nasal saline irrigation 0.9% on symptoms score,NMCT, and eosinophil count. Method: Interventional study, randomized controlled trial at a wood factoryduring January – March 2016. Samples which fulfilled inclusion and exclusion criteria, were examinedtheir nasal symptoms score by SNOT20, NMCT time, and nasal eosinophil count. Treatment group wasgiven nasal saline irrigation 0.9% twice a day and always wore mask during work. On the other hand,control group only wore mask during work. The treatment was given for two weeks and reexamination ofSNOT20 symptoms score, NMCT time and nasal eosinophil count were conducted afterwards. Comparativeanalysis test between two groups in this study was using unpaired t-test. Results: There were 36 samplesin this study, 18 as control group and 18 as treatment group. We found that nasal symptoms score andNMCT time after the treatment were improved, compared to the control group (p<0.05). Neverthelessnasal eosinophil count in the treatment group was not improved compared to the control group (p=0.324).Conclusion: Nasal saline irrigation 0.9% gave positive effect to the improvement of the nasal symptomsscore and NMCT, but it had no significant influence to the nasal eosinophil count.Keywords: Wood dust, mucocilliary transport, SNOT20, eosinophil, nasal saline irrigation

Gangguan pendengaran dan gangguan jalan napas bagian atas pada Mukopolisakaridosis tipe II Tri Juda Airlangga
Oto Rhino Laryngologica Indonesiana Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018
Publisher : PERHATI-KL

Latar belakang: Penyakit Mukopolisakaridosis (MPS) tipe II atau sindrom Hunter adalah gangguan terkait dengan kromosom X resesif yang disebabkan defisiensi enzim iduronate-2-sulfatase sehingga memicu penimbunan heparan sulfat dan dermatan sulfat. Gangguan pada pendengaran dan pernapasan bagian atas merupakan masalah umum yang terjadi pada penyakit ini. Tujuan: Untuk memberikan informasi mengenai gangguan pendengaran dan gangguan pernapasan bagian atas pada penyakit MPS tipe II. Kasus: Tiga pasien terdiagnosis MPS tipe II dengan gangguan pendengaran dan hipertrofi adenoid. Metode: Didapatkan 4 jurnal yang relevan setelah dilakukan penelusuran literatur dan penapisan dengan kriteria inklusi dan eksklusi. Hasil: Empat jurnal yang terdiri dari 3 laporan kasus dan 1 artikel penelitian menggambarkan gangguan pendengaran dan gangguan jalan napas bagian atas pada pasien dengan mukopolisakaridosis tipe II. Kesimpulan: Pendekatan multidisipliner diperlukan untuk mendiagnosis serta mengobati pasien MPS tipe II secara dini, agar dapat menunjang perkembangan individu dan sosial serta meningkatkan kualitas hidup pasien. Background: Mucopolysaccharidoses (MPS) type II is X-linked recessive disorder caused by iduronate-2-sulfatase enzyme deficiency and leads to the accumulation of heparan sulfate and dermatan sulfate. Hearing loss and upper respiratory track problems are commonlyoccur in this disorder. Purpose:To provide information about hearing loss and upper airway problems in MPS type II disorder. Cases: Three patients had been diagnosed as mucopolysaccharidoses type II with hearing loss and adenoid hypertrophy.Methods: Four relevant journals were obtained after literature searching and screening was performed using inclusion and exclusion criteria. Results: Out of 4 journals, 3 case reports and 1 research article were describing hearing loss and upper respiratory problems in patients with MPS type II. Conclusion:Multidisciplinary approach is needed for making early diagnosis and determining the treatment of mucopolysaccharidoses type II patients, in order to support individual and social development and to improve the patients’quality of life.

Efektivitas imunoterapi terhadap gejala, temuan nasoendoskopik dan kualitas hidup pasien rinosinusitis alergi Yuwan Pradana; Teti Madiadipoera; Melati Sudiro; Arif Dermawan
Oto Rhino Laryngologica Indonesiana Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012
Publisher : PERHATI-KL

Background: Rhinosinusitis is one of major health problems which increased the economic burden. With symptoms include nasal congestion, rhinorrhea, facial pain, and sometimes reduced or loss of smell, this condition may impair work productivity and quality of life (QOL). Rhinosinusitis is one of the comorbidity of allergic rhinitis. Allergen specific immunotherapy provides protection against the occurence of allergic symptoms and inflammatory reactions due to allergen exposure, that results in improvement of QOL of allergic rhinosinusitis patients. To assess the effectiveness of immunotherapy in the severity of the disease, nasal symptoms, nasoendoscopic findings, drugs intake, and the QOL in allergic rhinosinusitis patients treated with specific immunotherapy. Methods: A retrospective descriptive study conducted at the Rhinology-Allergy Clinic of ORL-HNS Department, Dr.Hasan Sadikin General Hospital, Bandung, on January - December 2011, towards 25 patients, by anamnesis, severity of the disease using Visual Analogue Scale (VAS), nasal symptoms from Weeke, Davis and Okuda, nasoendoscopic findings from Lund-Kennedy, drug intake score, and QOL assesment using Rhinoconjuctivitis Quality of Life Questionaire. Results: There was a significant correlation (p<0,05) between specific immunotherapy for 1 year observed by reduced disease severity, reduced nasal symptoms, nasoendoscopic findings improvement, reduced drug intake, and increased Quality of Life which shows significant results from 3 months after immunotherapy using Wilcoxon differential test (p<0,001). Conclusion: Immunotherapy for 1 year was significantly reduced disease severity, reduced nasal symptoms, improved nasoendoscopic findings, reduced drug intake, and improvement of QOL in patients with allergic rhinosinusitis began from 3 months after immunotherapy and maintained afterwards. Key words: allergic rhinosinusitis, nasal symptoms, nasoendoscopy, specific immunotherapy, quality of life Abstrak : Latar belakang: Rinosinusitis merupakan salah satu masalah kesehatan yang semakin meningkat sehingga menjadi beban besar terhadap perekonomian masyarakat. Dengan gejala berupa hidung tersumbat, rinore, nyeri pada wajah dan dapat disertai berkurang atau hilangnya penciuman, kondisi ini dapat menurunkan produktivitas kerja dan kualitas hidup. Rinosinusitis merupakan salah satu komorbiditas dari rinitis alergi. Imunoterapi alergen spesifik bertujuan untuk memberikan perlindungan terhadap timbulnya gejala alergi dan reaksi inflamasi akibat pajanan alergen, sehingga dapat meningkatkan kualitas hidup pasien rinosinusitis. Tujuan: Membuktikan efektivitas imunoterapi terhadap tingkat beratnya penyakit, gejala hidung, nasoendoskopi, penggunaan obat dan kualitas hidup pasien rinosinusitis alergi yang diberikan pengobatan imunoterapi selama 3, 6, dan 12 bulan. Metode: Dilakukan penelitian deskriptif retrospektif, di Poliklinik Rinologi Alergi Ilmu Kesehatan THT-KL RSHS Bandung, dalam periode JanuariDesember 2011 pada 25 pasien, menggunakan anamnesis, tingkat berat penyakit berdasarkan Visual Analogue Scale (VAS), gejala hidung berdasarkan Weeke, Davis dan Okuda, pemeriksaan nasoendoskopi berdasarkan Lund-Kennedy, penggunaan obat dan penilaian kualitas hidup dengan Rhinoconjuctivitis Quality of Life Questionaire. Hasil: Didapatkan hubungan bermakna berdasarkan uji chi-kuadrat-Friedman antara imunoterapi selama 1 tahun (p<0,05) terhadap penurunan tingkat berat penyakit, penurunan gejala hidung, perbaikan temuan nasoendoskopi, penurunan penggunaan obat, serta peningkatan kualitas hidup. Didapat perbaikan secara bermakna sejak 3 bulan pasca imunoterapi (p<0,001) berdasarkan uji beda Wilcoxon. Kesimpulan: Imunoterapi selama 1 tahun efektif terhadap penurunan tingkat berat penyakit, penurunan gejala hidung, perbaikan temuan nasoendoskopi, penurunan penggunaan obat, serta peningkatan kualitas hidup pada pasien rinosinusitis alergi, dengan perbaikan sejak 3 bulan dan bertahan hingga 1 tahun pasca-imunoterapi. Kata kunci: rinosinusitis alergi, gejala hidung, nasoendoskopi, imunoterapi, kualitas hidup

Page 3 of 49 | Total Record : 481

1 2 3 4 5

Filter by Year

2004 2025

Filter By Issues

All Issue Vol. 55 No. 1 (2025): VOLUME 55, NO. 1 JANUARY - JUNE 2025 Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024 Vol. 54 No. 1 (2024): VOLUME 54, NO. 1 JANUARY - JUNE 2024 Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023 Vol. 53 No. 1 (2023): VOLUME 53, NO. 1 JANUARY - JUNE 2023 Vol 52, No 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022 Vol. 52 No. 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022 Vol. 52 No. 1 (2022): VOLUME 52, NO. 1 JANUARY - JUNE 2022 Vol 52, No 1 (2022): VOLUME 52, NO. 1 JANUARY - JUNE 2022 Vol 51, No 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021 Vol. 51 No. 2 (2021): VOLUME 51, NO. 2 JULY - DECEMBER 2021 Vol 51, No 1 (2021): Volume 51, No. 1 January - June 2021 Vol. 51 No. 1 (2021): Volume 51, No. 1 January - June 2021 Vol. 50 No. 2 (2020): Volume 50, No. 2 July - December 2020 Vol 50, No 2 (2020): Volume 50, No. 2 July - December 2020 Vol 50, No 1 (2020): Volume 50, No. 1 January - June 2020 Vol. 50 No. 1 (2020): Volume 50, No. 1 January - June 2020 Vol 49, No 1 (2019): Volume 49, No. 1 January-June 2019 Vol 49, No 1 (2019): Volume 49, No. 1 January-June 2019 Vol. 49 No. 1 (2019): Volume 49, No. 1 January-June 2019 Vol 49 (2019): Volume 49, No. 2 July - December 2019 Vol. 49 (2019): Volume 49, No. 2 July - December 2019 Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018 Vol 48, No 2 (2018): Volume 48, No. 2 July - December 2018 Vol 48, No 1 (2018): Volume 48, No. 1 January - June 2018 Vol 48, No 1 (2018): Volume 48, No. 1 January - June 2018 Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017 Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017 Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017 Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017 Vol 46, No 2 (2016): Volume 46, No. 2 July - December 2016 Vol 46, No 2 (2016): Volume 46, No. 2 July - December 2016 Vol 46, No 1 (2016): Volume 46, No. 1 January - June 2016 Vol 46, No 1 (2016): Volume 46, No. 1 January - June 2016 Vol. 45 No. 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 2 (2015): Volume 45, No. 2 July - December 2015 Vol 45, No 1 (2015): Volume 45, No. 1 January - June 2015 Vol 45, No 1 (2015): Volume 45, No. 1 January - June 2015 Vol 44, No 2 (2014): Volume 44, No. 2 July - December 2014 Vol 44, No 2 (2014): Volume 44, No. 2 July - December 2014 Vol 44, No 1 (2014): Volume 44, No. 1 January - June 2014 Vol 44, No 1 (2014): Volume 44, No. 1 January - June 2014 Vol 43, No 2 (2013): Volume 43, No. 2 July - December 2013 Vol 43, No 2 (2013): Volume 43, No. 2 July - December 2013 Vol 43, No 1 (2013): Volume 43, No. 1 January - June 2013 Vol 43, No 1 (2013): Volume 43, No. 1 January - June 2013 Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012 Vol 42, No 2 (2012): Volume 42, No. 2 July - December 2012 Vol 42, No 1 (2012): Volume 42, No. 1 January - June 2012 Vol 42, No 1 (2012): Volume 42, No. 1 January - June 2012 Vol 41, No 2 (2011): Volume 41, No. 2 July - December 2011 Vol 41, No 2 (2011): Volume 41, No. 2 July - December 2011 Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011 Vol 41, No 1 (2011): Volume 41, No. 1 January - June 2011 Vol 40, No 2 (2010): Volume 40, No. 2 July - December 2010 Vol 40, No 2 (2010): Volume 40, No. 2 July - December 2010 Vol 34 (2004): Volume 34, No. 4 October - December 2004 More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
Dini Widiarni Widodo

Contact Email
journalorli@gmail.com

Phone
-

Journal Mail Official
journalorli@gmail.com

Editorial Address
-

Location
Unknown,

Unknown

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Dini Widiarni Widodo

Contact Email journalorli@gmail.com

Phone -

Journal Mail Official journalorli@gmail.com

Editorial Address -

Location Unknown, Unknown INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Dini Widiarni Widodo

Contact Email
journalorli@gmail.com

Phone
-

Journal Mail Official
journalorli@gmail.com

Editorial Address
-

Location
Unknown,

Unknown

INDONESIA