ISM (Intisari Sains Medis) : Jurnal Kedokteran
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Articles
1,063 Documents
<![CDATA[The conventional management of periapical cyst caused by post-dental treatment failure: A case report ]]>
<![CDATA[Florence Ariyana Manuputty]]>;
<![CDATA[Sylvyana M]]>;
<![CDATA[Tasman A]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018) ]]>
Publisher : <![CDATA[DiscoverSys Inc. ]]>
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DOI: 10.15562/ism.v9i2.269
<![CDATA[Background: Periapical cyst is the typical type of cyst that found in dental practices. Periapical cyst is an advanced phase of dental infection due to caries. Untreated caries will leads to pulpitis and develop to pulp necrosis. Periapical cyst is formed following the necrotic pulp. This study aims to describe the conventional management by enucleation technique to periapical cyst due to post-dental treatment failure.Case Description: A 22-years-old female patient came to oral and maxillofacial surgery clinic with a chief complaint of palatal swelling since eight months ago. On clinical examination, there was palatal swelling of 2x1x1 cm in size and radiograph showed a periapical cyst about pulp gangrene of teeth 21 and 22. Trauma history was found about 5 years ago with anterior teeth fractured and treated with restoration. The cyst was treated by enucleation and extraction was carried out for pulp gangrene teeth. There was no obturator insertion. The treatment showed a good prognosis and no secondary infection noticed.Conclusion: The treatment of periapical cyst was successfully by non-surgery conventional therapy with endodontic treatment and surgery method by enucleation for the bigger lesion. Cyst enucleation can be done without any complication, such as periodontal tissue damage.]]>
<![CDATA[Efek penutupan Diastema menggunakan Silicone Guide dengan Komposit Nanofiller: Laporan Kasus ]]>
<![CDATA[Rudy Djuanda]]>;
<![CDATA[Fadli Azhari]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018) ]]>
Publisher : <![CDATA[DiscoverSys Inc. ]]>
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DOI: 10.15562/ism.v9i2.270
<![CDATA[Background: Midline diastema is an aesthetic problem that can occur in anterior teeth where the closure of it can be performed by direct composite restorations. This study aims to see the benefits of using silicone guides and nanofiller composite resins to provide a smooth and esthetic restoration surface effect on the diastema closure.Case Description: A 24-year-old woman came to the clinic with complaints of a gap in the front teeth which was considered to be very disturbing appearance. Patients had a desired to fix their teeth due to uncomfortable feeling when smiling. Clinically, there was a diastema between the teeth 11 and 21. There was no caries found and teeth were found to be vital. While other teeth had a normal shape and there was no gap between the teeth. The gingival tissues around the tooth look normal and good oral hygiene and there was no low frenulum. Diastema closure using nanofiller composite restorations showed a good prognosis.Conclusion: Midline diastema closure using silicone guide can provide precise results according to the analysis, either on the anatomy of the palatal, labial and dental midline. The use of nanofiller composite resins at the closure of midline diastemic can provide advantages of both strength and maximum polishing results.]]>
<![CDATA[Pengaruh kombinasi Surface Pre-Treatment dan waktu inisiasi penyinaran terhadap kebocoran Mikro Restorasi RMGIC di RSGM Provinsi Sumatera Selatan ]]>
<![CDATA[Aisyah Humairah]]>;
<![CDATA[Rinda Yulianti]]>;
<![CDATA[Martha Mozartha]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018) ]]>
Publisher : <![CDATA[DiscoverSys Inc. ]]>
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DOI: 10.15562/ism.v9i2.271
<![CDATA[Background: Microleakage of RMGIC may occur due to smear layer interfere with the adhesion mechanism. Surface pretreatment to remove smear layer has been suggested. This study aims to evaluate the effect of combination surface pretreatment (dentin conditioner and acid-etch) and delayed light initiation on microleakage RMGIC restoration.Methods: Class V cavities were prepared on 32 maxillary premolars which have fulfilled inclusion criteria and randomly divided into 4 groups. Cavities were pretreated with dentin conditioner (group I and II) and acid-etch (groups III and IV). All cavities were restored with RMGIC and immediate light initiation (group I and III), delayed light initiation for 3 minutes (group II and IV). All specimens were thermo-cycled and immersed in Rhodamine-B 2% dye solution for 24 hours at 37° C. Specimens were sectioned parallel to the axis of the tooth and the extent of Rhodamine-B dye penetration was examined under a USB Digital Microscope.Results: Statistical analysis revealed significant differences between time initiation group (3 minutes and 0 minutes) (P < 0.05). T-test results showed a significant difference between groups I and IV and Group III and IV (P< 0.05).Conclusion: This study showed that there is no effect of the combined surface pretreatment and delayed light initiation on microleakage RMGIC restoration]]>
<![CDATA[Efektifitas ekstrak lidah buaya terhadap jumlah sel fibroblast pada proses penyembuhan luka incisi marmut ]]>
<![CDATA[Putu Sulistiawati Dewi]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018) ]]>
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DOI: 10.15562/ism.v9i3.272
<![CDATA[Latar belakang : Proses pembedahan seringkali melibatkan tindakan insisi yang dapat menyebabkan kerusakan jaringan, dimana kerusakan jaringan ini akan menstimulasi terjadinya proses pemulihan atau yang biasa disebut dengan proses penyembuhan luka. Penyembuhan luka merupakan proses yang dinamis dan terdiri dari fase inflamasi, fase proliferasi dan fase maturasi. Sel fibroblas mulai muncul pada fase proliferasi. Salah satu tanaman herbal yang berperan dalam penyembuhan luka adalah lidah buaya yang berkhasiat membantu proses regenerasi sel, anti bakteri, anti jamur dan anti inflamasi Tujuan : Penelitian ini dilakukan untuk mengetahui efektifitas ekstrak lidah buaya terhadap jumlah sel fibroblas dalam proses penyembuhan luka insisi pada hewan marmut. Metode : Penelitian ini menggunakan 9 ekor marmut jantan dewasa berumur 5-6 bulan dengan berat sekitar 700-800 gram. Dua buah luka insisi dibuat pada punggung masing-masing marmut dengan panjang insisi kurang lebih 1,5 cm, kedalaman 2 mm dan dengan jarak antar insisi kurang lebih 3 cm, insisi dibuat vertikal pada daerah punggung marmut. Luka insisi pertama kemudian diberi perlakuan dengan ekstrak lidah buaya 75% sebagai kelompok uji, sedangkan luka insisi kedua diberi aquades sebagai kelompok kontrol. Perlakuan diberikan selama 4 hari, pada hari ke-5 semua hewan uji didekapitasi dan dilakukan pemeriksaan histologi untuk menghitung jumlah sel fibroblas kemudian dianalisis menggunakan uji Independent t-test. Hasil penelitian : terdapat perbedaan yang signifikan antara jumlah sel fibroblas kelompok uji dengan jumlah sel fibroblas kelompok kontrol (sig < 0,05). Kesimpulan : pemberian ekstrak lidah buaya 75% dapat meningkatkan jumlah sel fibroblas dalam proses penyembuhan luka insisi pada marmut.]]>
<![CDATA[Inhibition effect of hydrocolloid irreversible alginate on soaking spray using aloe vera juice ]]>
<![CDATA[Dedi Sumantri]]>;
<![CDATA[Chaira Maulida]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018) ]]>
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DOI: 10.15562/ism.v9i3.274
<![CDATA[Introduction: Alginate impression material is the most commonly used in dentistry to get a negative mold of the oral tissues. Alginate impression material has imbibition effect when in contact with the liquid during the disinfection process. This study aimed to observe the imbibition effect on alginate impression material soaked and sprayed using Aloe vera juice.Methods: The research method used was a laboratory experimental with pretest and posttest. Alginate was molded by using a mold with the size of 28 mm in diameter and 18 mm high. The results of molding alginate were soaked and sprayed using Aloe vera juice 100% for 5 minutes and 10 minutes. Calculation of imbibition was performed by weighing using digital scales. The normality tested by Shapiro-Wilk and the data were analyzed by Mann Whitney.Result: The results showed that there were imbibition effects on alginate molding soaked and sprayed for 5 minutes and 10 minutes, the test indicated that there were significant differences (p<0.05) between 10 minutes and 5 minutes soaking. Meanwhile, between 5 minutes and 10 minutes spraying, no significant difference was obtained (p>0.05).Conclusion: This study concludes that it occurs the smallest imbibition effect on a spraying treatment using Aloe vera 100% for five minutes.]]>
<![CDATA[Pengaruh suhu penyimpanan terhadap kedalaman pengerasan dan kekuatan resin komposit ]]>
<![CDATA[Kholidina Imanda Harahap]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018) ]]>
Publisher : <![CDATA[DiscoverSys Inc. ]]>
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DOI: 10.15562/ism.v9i3.275
<![CDATA[Introduction: Temperature plays a role in polymerization process of composite resin. Depth of cure is often used as a marker of polymerization adequacy in composite resins. Adequate polymerization will increase the mechanical properties of composite resin. The aim of this study was to evaluate the effect of storage temperature on depth of cure and compressive strength of composite resin. Method: Samples were made from nanofiller composite resin (Filtek Z350 XT,3M,ESPE,USA) after the materials were stored at 4°C and 24°C for two weeks. Twenty samples of nanofiller composite resins for each test group were prepared using metal mould with 6 mm in diameter and 4 mm thick. Samples were cured under visible blue light for 20 second. The polymerized composite resin was measured for determining the depth of cure. Compressive strength of samples was tested by using Universal Testing Machine. Result: The results showed that depth of cure value of 24°C (3.90 ± 0.07 mm) was higher than 4°C (3.83 ± 0.17 mm) and compressive strength of 24°C (35.20 ± 4.63 MPa) was higher than 4°C (26.47 ± 3.13 MPa). Statistical analysis showed that depth of cure were no siginificant differences (p > 0.05) but in compressive strength were significant differences between test groups (p < 0.05). Conclusion: Storage temperature can affect the depth of cure and compressive strength of composite resin, although no significant difference on the depth of cure.]]>
<![CDATA[Insiden Malaria, penunjang diagnostik, dan hubungannya dengan curah hujan di Kecamatan Golewa Selatan, Ngada, NTT periode Oktober 2014 – April 2016 ]]>
<![CDATA[Stephanie Darda Susilowati]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 2 (2018): (Available online: 1 August 2018) ]]>
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DOI: 10.15562/ism.v9i2.276
<![CDATA[Latar belakang: Malaria masih banyak ditemui. Di Indonesia, terutama bagian timur. NTT menduduki prevalensi ketiga terbanyak di Indonesia setelah Papua Barat dan Papua. Insiden malaria yang berfluktuasi sepanjang tahun diduga berhubungan dengan curah hujan setempat. Perlu uji diagnostik yang akurat untuk mengkonfirmasi adanya parasit dalam darah pada setiap penderita dengan gejala klinis yang bervariasi, terutama di daerah endemis. Tujuan penelitian: Tujuan dari penelitian ini adalah untuk mengetahui pola kasus malaria di kecamatan Golewa Selatan, melihat perbedaan metode diagnostik malaria, dan melihat hubungan curah hujan dan kejadian malaria. Metode: Penelitian ini merupakan studi observasional dan studi pre-eksperimental yang diuji dengan chisquare dan uji koreksi lanjutan. Sampel berupa penderita suspek malaria yang dilakukan dua pemeriksaan laboratorium (RDT malaria dan uji sediaan tebal malaria). Sedangkan data observasional diambil dari rekam medik seluruh penderita malaria dan data curah hujan dari BMKG Kupang. Hasil: Hasil penelitian ini menunjukkan klinis diare terutama dijumpai pada usia balita, muntah pada usia remaja, dan nyeri punggung pada usia dewasa. Penderita perempuan lebih banyak dibanding pria. Tidak ditemukan hubungan antara curah hujan dengan insiden malaria di kecamatan Golewa Selatan selama bulan Januari 2014 hingga April 2016 (p=0,184). Tidak ada perbedaan yang bermakna antara hasil uji diagnostik malaria menggunakan RDT malaria dibanding pemeriksaan sediaan tebal (p=0,632). Simpulan: Disarankan meningkatkan kualitas pemeriksaan mikroskopik dan penelitian yang lebih lama untuk melihat lebih jelas korelasi curah hujan dan dikaitkan dengan topografi spesifik daerah setempat.]]>
<![CDATA[Prevalensi anemia pada ibu hamil di Puskesmas IV Denpasar Selatan Tahun 2015 ]]>
<![CDATA[Yayang Christian]]>;
<![CDATA[I Wayan Putu Sutirta Yasa]]>
<![CDATA[ Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019) ]]>
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DOI: 10.15562/ism.v10i2.277
<![CDATA[Introduction: The prevalence of pregnant women with anemia is quite high in Indonesia up to 63.5%. Though anemia can cause various complications in the fetus and in pregnant women themselves. There is still no data supporting the prevalence of anemia in pregnant women in Bali Province. The purpose of this study was to find the prevalence of anemia in pregnant women in Bali Province, especially the city of Denpasar and complete the data library regarding anemia in preganancy in Indonesia.Method: The research used cross-sectional design, and secondary data collection from medical record of Primary Health Care IV South Denpasar year 2015.Result: Anemia pregnant women amounted to 166 of total 521 pregnant women with 31.9% prevalence, with an average of 43 cases of pregnant women with anemia every month.Conclusion: From the data obtained found the prevalence of pregnant women who suffer from anemia is still relatively high (31.9%).]]>
<![CDATA[Hubungan antara obesitas dan insiden kanker kolorektal di RSUP Sanglah tahun 2016-2017 ]]>
<![CDATA[Anak Agung Sagung Mirah Trisuladara]]>;
<![CDATA[Made Agus Dwianthara Sueta]]>;
<![CDATA[Made Suka Adnyana]]>
<![CDATA[ Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019) ]]>
Publisher : <![CDATA[DiscoverSys Inc. ]]>
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DOI: 10.15562/ism.v10i2.278
<![CDATA[Introduction: Colorectal cancer is the third malignant disease in Indonesia. Obesity is one of the risk factors related to colorectal cancer. This research aims to role out relationships between obese and age to the incidence of colorectal cancer at Sanglah General Hospital.Method: Study design using case-control analytic model, covering 274 samples, divided into the group of colorectal cancer (137 persons) and non-cancer samples (137 persons). Secondary data were used for analysis obtained from medical records in year period of 2016-2017 at Sanglah General Hospital. Data were analyzed using Chi-square analysis and risk estimate model.Result: The result showed that the majority of colorectal cancer patients were male (53.3%), meanwhile for non-cancer patients were female (50.4%). The average age of colorectal cancer patients was 54 years old while 42 years for non-colorectal cancer patients. Based on the BMI groups, majority of cancer colorectal patients (62%) belongs to obese, while only 39.4% for non-colorectal cancer patients. Result of analysis showed that there is significant relationship between obese and the incidence of colorectal cancer (p value <0.001), with the risk increase of prevalence by 1.588 times higher for those patients with BMI ≥23.00 kg/m2 (95% CI 1.235-2.040). Result from the Chi-square test also indicated that there is significant relationship between age above 40 years and the incidence of colorectal cancer (p value <0.001).Conclusion: It can be concluded that there is significant relationships between obese and age above 40 years to the incidence of colorectal cancer.]]>
<![CDATA[Ethanolic extract cream of red cabbage (Brassica oleracea L. var. capitata f.rubra) on the epidermal thickness in Wistar rats (Rattus norvegicus) after ultraviolet-B exposure ]]>
<![CDATA[Yogarani V.C Rajappan]]>;
<![CDATA[I Gusti Kamasan Arijana]]>;
<![CDATA[I Wayan Sugiritama]]>;
<![CDATA[IGA Dewi Ratnayanti]]>
<![CDATA[ Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018) ]]>
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DOI: 10.15562/ism.v9i3.279
<![CDATA[Background: UV exposure is related to oxidative stress and also as an essential factor in skin photoaging. Several antioxidants are widely used in preventing skin photoaging by influencing epidermal skin layer. High concentrations of antioxidant properties in red cabbage are known to have these effects. This study aims to determine the role of ethanolic extract cream of red cabbage on the epidermal thickness in Wistar rats after UV-B exposure.Methods: An experimental study was carried out among 25 Wistar rats which divided into 5 groups as follows: P1 as control (only exposed to UB-B), P2 (placebo and UV-B), P3 (5% ethanolic extract cream and UV-B), P4 (10% ethanolic extract cream and UV-B), and P5 (20% ethanolic extract cream and UVB). The UV-B dosage applied for each group was 65 mJ/cm2. The thickness of epidermis is calculated by direct measurement using Image Raster software from basal membrane to stratum corneum. The statistical analyses were performed using SPSS ver. 20.0.Results: There was a significantly different in the epidermal thickness among groups (P < 0.05). The mean of epidermal thickness in the control group (P1) was 36.00±1.08 µm, followed by 27.66±0.87 µm in the treatment group I (P2), 26.76±1.02 µm in the treatment group II (P3), 24.94±1.25 µm in the treatment group III (P4), and 20.24±1.47 µm in the treatment group IV (P5).Conclusion: The ethanolic extract cream of red cabbage (Brassica oleracea L.Var. capitata f. rubra) in different doses have a statistically significant impact on the epidermal thickness in Wistar rats after UV-B exposure.]]>
