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INDONESIA
ISM (Intisari Sains Medis) : Jurnal Kedokteran
Published by Universitas Udayana
ISSN : 25033638     EISSN : -     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.
Arjuna Subject : -
Articles 1,063 Documents
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The influence of light physical activity on scale of pain in elderly with knee osteoarthritis Prasenah Subramaniam; Nyoman Astika; Ketut Mariadi
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.194 KB) | DOI: 10.15562/ism.v10i2.293

Abstract

Background: Osteoarthritis (OA) is a collection of mechanical variations of joint thinning, including the articular ligament and the subchondral bone.Aim: This study aims to find out how some light physical activity correlates with the pain scale among elderly with knee osteoarthritis and also to find out whether light physical activity in the elderly helps reduce pain in knee osteoarthritis.Method: This research is a descriptive cross sectional study. The sample in this study was elderly people aged 50 years and above with a total of 70 samples were selected using multistage random sampling technique located in Badung Market, Kumbasari Market, and Renon Field. Data were obtained by interviewing respondents who previously provided informed consent using structured questionnaires. The degree of pain caused by osteoarthritis was measured using The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and the total score.Results: Distribution of sex within samples found that women (54.3%) and men (45.7%). Researchers found that the mean age of respondents was 61.2 (SD + 3.75) years. The total number of respondents who have exercise habits is 52.9%. The average WOMAC score was 23 (SD +2,319) with a minimum score of 18 and a maximum of 27. Respondents with WOMAC score <23 were 52.9% whereas respondents with WOMAC score> 23 were 47.1%. Cross-tabulation results showed 97.3% of respondents with a WOMAC score <23 had exercise habits.Conclusion: The exercise habits of the elderly with knee osteoarthritis can reduce pain when measured using a 0-4 scale and the WOMAC pain scale.
The effect of purple mangosteen (Garcinia mangostana) peel extract on collagen fiber in male Wistar rats after Ultraviolet-B (UV-B) exposure Tarvin Jit Singh Gill; I Gusti Ayu Dewi Ratnayanti; I Gusti Kamasan Nyoman Arijana
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (669.557 KB) | DOI: 10.15562/ism.v9i3.295

Abstract

Background: Skin aging can be caused by long-term ultraviolet (UV) exposure that usually called as photoaging. Administered antioxidant substances can delay the photoaging process. Purple mangosteen is known to have abundant antioxidant properties such as xanthones and anthocyanins. This study aims to determine the effect of purple mangosteen peel extract on the collagen fiber in male Wistar rats after UV-B exposure.Methods: An experimental study was conducted among 21 male Wistar rats at Histology Laboratorium, Udayana University from a period of March-October 2017. The samples were divided into 3 groups as follows: control, placebo, and mangosteen extract with 7 rats in each group. Collagen fiber was assessed by using a light microscope with 400 times magnification. Statistical analysis was carried out using SPSS ver. 21 software using one way ANOVA.Results: The study found that percentage of collagen area within control group was 61.94%, placebo group 72.90%, and mangosteen peel extract 73.63%. The mean between-group analyzed using one way ANOVA found that there was a statistically significant difference in mangosteen peel extract than control group (p=0.0000), but not statistically significant if compared with placebo group (p=0.640) on the collagen fiber in male Wistar rats.Conclusion: there was a statistically significant difference in mangosteen peel extract than control group on the thickness of collagen fiber in male Wistar rats after UV-B exposure.
Pengaruh kepatuhan pendokumentasian asuhan medis terhadap kelengkapan dokumen pengajuan klaim JKN di Instalasi Rawat Inap RSUD Badung tahun 2018 Raditya Putra Pratama Suryadhi; Dyah Pradnyaparamita Duarsa; Komang Ayu Kartika Sari
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (209.84 KB) | DOI: 10.15562/ism.v10i2.298

Abstract

Background: BPJS as a health insurance institution runs the National Health Insurance (JKN) program. JKN implements a prospective financing system whereby payments made after the provision of services are in accordance with the agreement at the beginning in the form of packages. As regard with the fee, the hospital should take an effort to submit the proof document as the condition for the filing of the claim.Aim: This study aims to determine the effect of medical documenting compliance with the completeness of the JKN claim filing documents at the inpatient installation of Badung Hospital.Method: This study is a cross-sectional analytic study with the sample used is 120 documents of in-patient medical treatment that has been repatriated at the in-patient installation of Badung General Hospital in February 2018.  Results: This research get result that the price rs = 0.861 and p-value = 0,003.Conclusion: There is an effect of compliance with documenting medical care on the completeness of claim filing documents in the in-patient installation of Badung General Hospital.
Gambaran fraktur elbow pada anak-anak di RSUP Sanglah tahun 2012-2013 Ketut Arya Surya Pranata; IGST Ngurah Wien Arnaya
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.827 KB) | DOI: 10.15562/ism.v10i2.299

Abstract

Introduction: Fracture is a loss of bone continuity, either total or partial, usually caused by trauma. Fractures in children are more common due to the immature musculoskeletal system, this is because the child is more susceptible to tears on joint surfaces, epiphyseal plates, aphophyseal insertion of large tendon muscle units. This study aims to determine the prevalence of elbow fracture in children at Sanglah Hospital Denpasar in 2012 until 2013.Method: Study design using cross-sectional method, evaluating the characteristics of elbow fracture in children at Sanglah General Hospital in the period 2012 to 2013.Results: Males tend to have more elbow fractures compared with females with a 73% proportion, based on the cause of overall fracture of the sample due to falling during activity, based on the fracture type  more subjects experiencing fractures of the supracondylar humerus fracture compared with olecranon fractures as much as 93%.Conclusion: The prevalence of elbow fracture in children in Sanglah General Hospital in 2012-2013 is 15 cases, all caused by falling during the activity. The type of elbow fracture found in most children is a supracondylar humerus fracture.
Potensi FuMA stem cells, kombinasi fukoidan dan Bone Marrow Stem Cells (BMSCs), sebagai penatalaksanaan mutakhir pada Infark Miokard Akut Agung Bagus Sista Satyarsa; Sang Ayu Arta Suryantari; Putu Gupta Arya Gumilang; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (648.161 KB) | DOI: 10.15562/ism.v10i1.300

Abstract

Introduction: Acute myocardial infarction (AMI) is the leading cause of death worldwide. One of the causes of high morbidity and mortality is progressive and irreversible nature of the disease and current treatments are still not optimal in resolving these problems. Thus, this paper aims to describe the potential effect of combination of fucoidan and bone marrow stem cells (namely FuMA stem cells) as the novel management of AMI.Method: The method used in our paper was literature searching by including the keywords of AMI, BMSCs, and fucoidan.Result: Fucoidan from brown seaweed has shown a great potential effect as anti-inflammatory, anti-coagulant, anti-atherogenic, anti-oxidant, and anti-fibrotic. It limits the infarct area and increases SDF-1, CXCR4 and Akt expression as well as LVEF. However, fucoidan has not been able to regenerate cardiomyocyte cells in AMI. It takes a combination of BMSCs that have been shown to prevent the expansion of infarction area and improve post-infarction function.Conclusion: Thus, FuMA stem cells hold a great potential novel therapy for AMI. Further studies are needed to unveil the potential of FuMA stem cells in AMI management.
Gambaran penggunaan kontrasepsi hormonal dan non hormonal di wilayah kerja UPT Puskesmas Tampak Siring 1 Firdy Liwang; Agha Bhargah; I.B. Hendra Kusuma; Gede Giri Prathiwindya; I Gst Indaya Surya Putra; Luh Seri Ani
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.294 KB) | DOI: 10.15562/ism.v9i3.301

Abstract

 Pertumbuhan penduduk di Indonesia yang sangat pesat membutuhkan suatu stategi pencegahan untuk menanggulangi ledakan penduduk, metode keluarga berencana dapat menjadi solusi masalah tersebut. Sampai saat ini paradigma penggunaan kontrasepsi masih didominasi oleh penggunaan kontrasepsi jenis hormonal yang lebih diminati dibandingkan kontrasepsi non hormonal, walaupun mengingat berbagai efek samping yang dapat timbul dalam penggunannya. Mengingat banyaknya efek samping dalam penggunaan kontrasepsi hormonal, sehingga diperlukan suatu penelitian yang bertujuan untuk mendapatkan gambaran penggunaan kontrasepsi hormonal dan non hormonal di wilayah kerja UPT puskesmas Tampak Siring 1.Penelitian ini menggunakan rancangan cross-sectional deskriptif, subjek penelitian didapatkan melalui metode consecutive door to door sampling pada wanita di Desa Tampak Siring, dengan basis pengumpulan data melalui wawancara kuesioner.Penelitian ini menggunakan 95 subjek wanita yang saat ini menggunakan kontrasepsi baik jenis hormonal maupun non hormonal. Penggunaan kontrasepsi hormonal masih lebih banyak digunakan (62,1%) dengan jenis kontrasepsi Pil KB (30,5%) yang lebih banyak digunakan. Kemudian kontrasepsi non hormonal terbanyak adalah AKDR (25,3%). Selain itu analisis mengenai alasan penggunaan kontrasepsi menemukan penggunaan kontrasepsi hormonal lebih berdasarkan kemudahan menggunakan (77,8%), sedangkan pada kontrasepsi non hormonal lebih didasarkan alasan saran dari petugas kesehatan (57,6%). Penggunaan kontrasepsi hormonal masih mendominasi di wilayah kerja UPT Puskesmas Tampak Siring 1, selain itu alasan penggunaan kontrasepsi hormonal sebagian besar masih pada kemudahan penggunaan, bukan dari profil jenis kontrasepsi dan berbagai macam efek samping yang ditimbulkannya.
Polusi udara terkait lalu lintas dan kesehatan respirasi I Gusti Ngurah Bagus Artana; Ida Bagus Ngurah Rai
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (642.646 KB) | DOI: 10.15562/ism.v9i3.303

Abstract

Polusi udara meningkatkan risiko menderita berbagai masalah kesehatan, terutama di bidang respirasi. Pajanan polusi udara terkait lalu lintas bersifat involunter dan mengenai manusia sejak dalam kandungan hingga kematian. Polutan udara mengandung bahan-bahan seperti nitrogen dioksida, sulfur dioksida, karbon monoksida, benzene, ozon, particulate matter 10 (PM10), timbal, arsenik, cadmium, nikel, benzopyrene, dan particulate matter 2,5 (PM2.5) yang dapat mempengaruhi kesehatan paru. Menentukan hubungan sebab akibat berbagai polutan utama dari jalan raya terhadap system respirasi manusia merupakan hal yang sangat rumit dilakukan. Secara umum dapat disimpulkan, polutan terkait lalu lintas akan mencetuskan reaksi inflamasi yang akan bergulir sesuai variasi individu manusia yang terpajan. Konsep stress oksidatif akibat polutan terkait lalu lintas juga mulai banyak diteliti. Hal ini memberikan harapan dalam membantu mekanisme anti-oksidan manusia dalam menghadapi ancaman polusi udara yang semakin sulit dihindari.
SYOK SEPTIK DISERTAI HIPOKSIA HEPATIK PADA RUMAH SAKIT UMUM DAERAH KLUNGKUNG, BALI-INDONESIA: SEBUAH LAPORAN KASUS Putu Herdita Sudiantara; Juslaksmi Dharmapala
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.602 KB) | DOI: 10.15562/ism.v9i3.304

Abstract

Latar Belakang: Sepsis merupakan suatu kondisi sindroma klinik yang terjadi oleh karena respon tubuh yang berlebihan terhadap suatu infeksi yang meliputi proses inflamasi, autoimun, dan koagulasi. Penanganan sepsis membutuhkan diagnosis yang cepat serta terapi yang tepat untuk menurunkan angka mortalitas yang diakibatkan oleh kondisi ini. Laporan kasus ini bertujuan untuk memberikan gambaran sepsis yang disertai dengan hipoksia hepatik serta penanganan yang diberikan untuk menangani kondisi tersebut.Kasus: Pasien laki-laki 68 tahun datang diantar keluarga ke Rumah Sakit Umum Daerah Klungkung dengan keluhan penurunan kesadaran. pemeriksaan fisik ditemukan adanya sesak (laju respirasi 30 kali/menit), tekanan darah 60 mmHg per palpasi, saturasi 85% via non rebreathing mask oksigen 12 liter per menit, denyut nadi 122 kali per menit, GCS E1V3M4, suhu 35,9o C. Kedua sklera tampak mengalami ikterus, dari pemeriksaan fisik paru ditemukan adanya ronkhi bilateral, akral teraba dingin. Melalui pemeriksaan complete blood count ditemukan adanya leukositosis (26,3 x 109/L) dengan predominan limfosit (11,2 x 109/L). Dari pemeriksaan fungsi hati ditemukan adanya peningkatan SGOT (473 mg/dl) dan SGPT (208 mg/dl), total protein yag rendah (4,6 mg/dl), dan albumin yang rendah (2,5 mg/dl). Pemeriksaan fungsi ginjal ditemukan adanya peningkatan dari ureum (137 mg/dl) dan kreatinin (2,1 mg/dl).Simpulan: Penanganan sepsis harus didasarkan pada diagnosis cepat dan penanganan resusitasi yang tepat untuk mengurangi angka mortalitas yang disebabkan oleh sepsis.
Pola penggunaan insulin pada pasien diabetes mellitus tipe 2 di poli penyakit dalam RSU Negara Periode Juli - Agustus 2018 Komang ayu Vitriana Gamayanti; Ni Luh Made Novi Ratnasari; Agha Bhargah
Intisari Sains Medis Vol. 9 No. 3 (2018): (Available online: 1 December 2018)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.609 KB) | DOI: 10.15562/ism.v9i3.306

Abstract

Aim: This study aims to determine the pattern of insulin therapy in type 2 Diabetes Mellitus patient in Internal Medicine Policlinic Negara Hospital, Bali.Method: This research was an observational study with cross-sectional design at Internal Medicine Policlinic Negara Hospital, Bali period August 2018. A total of 177 samples were selected by total sampling technique.Result: According to the duration of action, majority of insulin usage was rapid acting insulin in 93 patients (52,5%). The most frequent combination of two insulin types was long-acting with rapid-acting insulin in 30 patients (33,7%), meanwhile the  most frequent combination of insulin and OHD was premixed insulin with gluconeogenesis inhibitor in 43 patients (48,9%). Fasting Plasma Glucose mean was 185,12 mg/dL, Post Prandial Plasma Glucose mean was 252,9 mg/dL. This study also found the Fasting Plasma Glucose ≥ 126 mg/dL count in 129 patients (72,9%), Post Prandial Plasma Glucose ≥ 180 mg/dl count in 133 patients (75,1%). The mean of systolic blood pressure was 128,81/ 78,53 mmHg, patients with targeted blood pressure <140/90 mm/Hg count in 110 patients (62,1%).Conclusion: The profile of insulin therapy in patients with Type 2 DM at Internal Medicine Polyclinic, Negara Hospital varies according to the indication in each patient. The most frequent type of insulin use is rapid acting insulin. Most patients with insulin therapy have not achieved targeted glycemic control, but have achieved the targeted blood pressure according to the PERKENI.
The risk of atopic dermatitis in post-term gestational age at Sanglah Hospital Denpasar: A preliminary study Made Ardinata; Ketut Dewi Kumara Wati; Wayan Dharma Artana; Hendra Santosa; Komang Ayu Witarini
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.2 KB) | DOI: 10.15562/ism.v10i1.307

Abstract

Backgrounds: Several studies reported that Atopic Dermatitis (AD) increases with gestational age. Prolong dominancy of Th2 activity during gestation might contribute to the risk of atopic disease in infancy or beyond the period. This study aimed to evaluate the risk AD in post-term gestational age.Methods: A prospective observational study was conducted among 73 living births at Sanglah Hospital Denpasar from December 2015 to January 2016 period. Infants were classified into 2 such as exposed (post-term) and non exposed (term and preterm) group. Parents-follow up by phone was carried out in 1 until 2 months interval. The study was finished once AD diagnosed, subject died or lost to follow up. Statistical analysis was carried out using SPSS ver. 20 software whereas P-value > 0.05 was considered significant.Results: About 20 (233%) infants were preterm, 36 (49.3%) a term, and 17 (23,3%) post-term. The median value of follow up duration was 28 (14-35) days. Based on AD, there were total 24 cases which divided into 15(62.5%), 8(33.3%) and 1(4.17%) cases of AD in post-term, aterm, and preterm respectively. The incidence rate of AD in post-term was 88.2% while in non-post-term the incidence rate was 16.1%. The relative risk (RR) of AD in post-term was 5.47 (95% CI 2.94-10.23; P = 0.001)Conclusion: Post-term is 5.47 times more likely to develop AD compared with aterm and preterm infant. In addition, the incidence rate of AD in post-term infant was 88.2% at Sanglah Hospital Denpasar

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