Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

All

Jurnal Farmasi Higea

higea
Website

Published by Sekolah Tinggi Ilmu Farmasi Padang

ISSN : - EISSN : 25413554 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Arjuna Subject : -

Articles 9 Documents

Search results for , issue "Vol 2, No 1 (2010)" : 9 Documents clear

Karakterisasi Ekstrak Spon Laut Axinella carteri Dendy Secara Fisika, Kimia Dan Fisikokimia Harrizul Rivai; Meliyana Meliyana; Dian Handayani
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Characterization of the liquid extract of marine sponge (Axinella carteri Dendy) has been carried out by using the physical, chemical and physicochemical methods. The physical character of the extract was yellowish brown liquid, smells fishy and bitter taste, with a specific gravity of 0.9644 ± 0.02576. The marine sponge contained alkaloids, steroids and terpenoids, with total alkaloid content of 0.9433% ± 0.136133%. In physicochemical analysis, residu on drying was 7.156% ± 0.2944%, ash content 2.5576% ± 0.2668%, acid insoluble ash 0.014% ± 0.0035%, concentration of substances dissolved in water 5.6153% ± 0.2759%, concentration of substances dissolved in ethanol was 6.4263% ± 0.4622%, levels of a substance extracted from each fraction was 0.9066% ± 0.0666% in hexane fraction, 0.1866% ± 0.03045% in chloroform fraction, 0.0616% ± 0.04297% in ethyl acetate fraction and 6.449% ± 0.07642% in water fraction. Profile of thin layer chromatography (TLC) showed the existence five stain with value Rf 0.1; 0.16; 0.3; 0.44 and 0.56.

Efek Diuretik dan Daya Larut Batu Ginjal Dari Ekstrak Daun Mangkokan (Nothopanax scutellarium. Merr) Elisma Elisma; Fitri Maya Sari; Helmi Arifin
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Research on the effects of diuretics and solubility of kidney stones of Mangkokan leaf (Nothopanax scutellarium Merr.) extract has been done. Testing the solubility of kidney stones performed on 4 groups of test animals, namely the control group (without extract), The treatment dose groups of 0.5%, 1%, and 2%. Level of kidney stones are dissolved in the control group, 0.5%, 1% and 2% are 0.00521%, 0.01232%, 0.02433% and 0.05669% respectively. These result indicate a difference in dissolving kidney stones. Diuretic effect tested on 15 white male rats were divided into 5 groups of tests, one positive control group (furosemide), 1 negative control group (tween 80 1%), 3 treatment groups (doses of 125; 250 and 500 mg/kg BW). The result showed that all of three doses of extract have diuretic effect.

Produksi Bioplastik Poli (3-Hidroksibutirat) (P(3HB)) Secara Proses Fermentasi Menggunakan Bakteri Bacillus brevis FAAC-20801 Dari Minyak Kelapa Sawit Sebagai Sumber Karbon Krisyanella Krisyanella; Mimi Susanti; Akmal Djamaan
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

The production of bioplastic P(3HB) with fermentation process by Bacillus brevis FAAC-20801 from palm oil as carbon has been carried out. The fermentation process was conducted throug at pH 7, 37oC and agitation rate of 200 rpm for 60 hours. The characterization of the bioplastic production was based on cell growth, P(3HB) content and P(3HB) percentage. Results showed that the optimum time was 48 hours, with fermentation biomassa 277 mg, P(3HB) content of 7.2 mg/ 20 mg biomassa (36 % b/b). Fermentation process in bioreactor produced P(3HB) higher than in rotary shaker incubator.

Profil Disolusi Parasetamol Mukoadhesif Menggunakan Kombinasi Polimer Natrium Karboksimetilselulosa dan Gom Arab Auzal Halim; Riri Hariyani; Maria Dona Octavia
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Dissolution profiles of 4 formulas of paracetamol mucoadeshif formulas has been done. The test done by using pH 5,8 phosphate buffer as dissolution medium with rowing method, as stated in the Indonesian Pharmacopoeia IV edition. Paracetamol concentrations were measured by UV spectrophotometer at 243 nm. The average dissolution from each formula at 60 minutes are 10.1641%, 15.015%, 11.0631% and 11.8493% respectively. Adhesion test of some mucoadhesive granule adhesion test formulated by using Na-CMC single polymer and a combination of Na-CMC and gum arabic done bioadhesif in vitro assay using rabbit intestinal tissue. The result showed that the combination of Na-CMC polymer and gum Arabic can be used as a polymer bioadhesif because it shows results that meet the requirements of the test bioadhesif.

Efek Diuretik dan Daya Melarutkan Batu Ginjal Dari Ekstrak Herba Pecut Kuda (Stachytarpheta jamaicensis (L)Vahl) Helmi Arifin; Masitah Masitah; Elisma Elisma
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

The herbal extract of pecut kuda’s potencies on dissolving kidney stones and it’s diuretic effect has been studied. Test dissolve kidney stones performed in vitro by dissolving the crystals or stones are usually found in the kidney. Test were carried out at 4 treatment groups, control (no extract), 0.1%; 1% and and 2% groups. In the control group, the levels of dissolved kidney stones at 52.116 ppm, while the group of 0.5%, 1% and 2% at 56.140 ppm, 61.592 ppm and 76.602 ppm respectively. One-way ANOVA test result and test advanced non-parametric Kruskal-wallis test showed that of the three consentrations of the extract has a difference in dissolving kidney stones. Diuretic effect tested on 15 white male rats were divided into 5 groups, where in the extract is administered orally. The test group was divided into a positive group (furosemide), 1 negative group (given Na-CMC) and the 3 treatment groups (125; 250 and 500 mg/kg BW). Volume of rat urine into variable observations. Based on the results of two-way ANOVA test and test advanced non-parametric Friedman test show that all three doses of the test has diuretic effect. So that the conclutions of this study are horse whip herbal extracts can dissolve kidney stones and has a diuretic effect on test animals.

Pengaruh Cara Pengeringan Oven Dan Microwave Terhadap Perolehan Kadar Senyawa Fenolat Dan Daya Antioksidan Dari Herba Meniran (Phyllanthus niruri L.) Zet Rizal; Fitri Ledia; Harrizul Rivai
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Effect of drying method in gaining of extractive, phenolic content and antioxidant activity from Phyllanthus niruri (Linn.) leaves have been investigated by UV-Visible spectrofotometric. The drying method tested were air-drying, microwave drying and oven drying at 400C. The determination of phenolics compounds was carried out accourding to Folin Ciocalteau method and antioxidant activity was evaluated by DPPH as oxidant and gallic acid as reference. The determination of extractive compounds showed that the air-drying, microwave drying and oven drying at 40 0C countained 17.54 %; 11.84 %; 14.22 % with the water content 8.2%; 6.6%; 6.7%. The phenolic compounds 2,63900 %; 2,24585 %; 2,28095 %. Then IC50 of the sample were 0.49 mg/mL, 0.51 mg/mL, 0.53 mg/mL respectively.

Pengaruh Cara Pengeringan Oven Dan Microwave Terhadap Perolehan Kadar Senyawa Fenolat Dan Daya Antioksidan Dari Daun Jambu Biji (Psidii folium) Maria Dona Octavia; Stephany Stephany; Harrizul Rivai
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Effects of drying methods in gaining of extracted material, phenolic content, and antioxidant activity in Psidii folium leaves have been investigated. The drying methods tested were air-drying, microwave oven-drying, and oven-drying at 60ºC. The determination of extracted material compound showed that the air-drying, microwave oven-drying, and oven-drying at 60ºC contained 184,767; 333,767; and 208,533 mg/g, phenolic of these sample were 46,0474; 53,8402; and 51,4532 mg/g, and IC50 of these sample were 0,529; 0,477; and 0,505 mg/mL. Among the drying methods tested, the highest extracted material, phenolic concentration, and antioxidant activity were by microwave oven-drying.

Penentuan Pengaruh Jenis Pelarut Ekstraksi Terhadap Perolehan Kadar Senyawa Fenolat dan Daya Antioksidan Dari Herba Miniran (Phyllanthus niruri L.) Zulharmitta Zulharmitta; Derisa Elrika; Harrizul Rivai
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

The influence of solvents on the gaining of phenolic compounds and antioxidant activity of meniran herbs (Phyllanthus niruri L.) have been evaluated. The meniran herbs were extracted with methanol-water, ethanol-water and acetone-water. Total phenolic content of these extracts were determined by using the Folin-Ciocalteau method and antioxidant activity of these extracts were determined by using DPPH method. The results showed that extraction with methanol-water, ethanol-water and acetone-water give extractives in ammount of 167.9, 152.8 and 135.7 mg/g, respectively. The total phenolic compound content of these extracts were 73.4584, 59.9798 and 48.9976 mg/g respectively. Where as the antioxidant activity (IC50 value) of these extract were 0.3987, 0.4323 and 0.4495 mg/mL, respectively.

Isolasi Flavonoid Dari Herba Sida Rhombifolia, Linn. Junuarti Jubahar; Husnal Hayati; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 2, No 1 (2010)
Publisher : STIFARM Padang

Flavonoid compounds have been isolated from Sida rhombifolia, Linn herbs. One kilogram of the dried herbs produced 1,7339 g ( 0.17339 % ) congealed extract and 3.87 mg of flavonoid A. Flavonoid A was yellow in colour, amorph solid which was decomposed at 232-234º C. Based on ultraviolet and infrared data and product of its hydrolysis, compound A was Flavonol-3-O-Galaktose.

Page 1 of 1 | Total Record : 9

Filter by Year

2010 2010

Filter By Issues

All Issue Vol 17, No 2 (2025) Vol 17, No 1 (2025) Vol 16, No 2 (2024) Vol 16, No 1 (2024) Vol 15, No 2 (2023) Vol 15, No 1 (2023) Vol 14, No 2 (2022) Vol 14, No 1 (2022) Vol 13, No 2 (2021) Vol 13, No 1 (2021) Vol 12, No 2 (2020) Vol 12, No 1 (2020) Vol 11, No 2 (2019) Vol 11, No 1 (2019) Vol 10, No 2 (2018) Vol 10, No 2 (2018) Vol 10, No 1 (2018) Vol 9, No 2 (2017) Vol 9, No 1 (2017) Vol 8, No 2 (2016) Vol 8, No 1 (2016) Vol 8, No 1 (2016) Vol 7, No 2 (2015) Vol 7, No 1 (2015) Vol 6, No 2 (2014) Vol 6, No 1 (2014) Vol 5, No 2 (2013) Vol 5, No 1 (2013) Vol 4, No 2 (2012) Vol 4, No 1 (2012) Vol 3, No 2 (2011) Vol 3, No 1 (2011) Vol 2, No 2 (2010) Vol 2, No 1 (2010) Vol 1, No 2 (2009) Vol 1, No 1 (2009) More Issue

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota padang,

Sumatera barat

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name -

Contact Email -

Phone -

Journal Mail Official -

Editorial Address -

Location Kota padang, Sumatera barat INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
-

Contact Email
-

Phone
-

Journal Mail Official
-

Editorial Address
-

Location
Kota padang,

Sumatera barat

INDONESIA