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Jurnal Farmasi Higea

higea
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Published by Sekolah Tinggi Ilmu Farmasi Padang

ISSN : - EISSN : 25413554 DOI : -

Core Subject : Health,

Medicine & Pharmacology

Arjuna Subject : -

Articles 8 Documents

Search results for , issue "Vol 3, No 1 (2011)" : 8 Documents clear

Aktifitas Stimulan Sistem Saraf Pusat Ekstrak Biji Pinang ( Areca catechu, L ) Terhadap Mencit Putih ( Mus musculus, L) Suhatri Suhatri; Yimmi Syavardie; Zet Rizal
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

The stimulant activity of central nerve systems of areca seed (Areca cathecu, L.), at white mouse ( Mus musculus, L ) had been done by using method hanging test, evasi test, swim test and discrimination maze. Drug dose given is 0.5 mg/20 gram BW white mouse, 1 mg/20 gram BW white mouse, 2 mg/ 20 gram BW white mouse in oral mechanism. As negative control is applied by Tween 80 2% and condensation of comparator is applied by Caffeine.Activity test result from seed extract Pinang ( Areca cathecu, L. ) to white mouse ( Mus musculus, L. ) the obtained result signifikan ( P < 0.01 ) as stimulant central nerve systems.

Pengaruh Pemberian Jus Wortel (Daucus carota, Linn) Terhadap Kadar Glukosa Darah Mencit Putih Betina Surya Dharma; Hendra Saputra; Netty Suharti
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Research on the effect of carrot juice (Daucus carota, Linn) on blood glucose levels of female white mice have been done. These experiments use advantage glucose meter (Roche) to measure the glucose blood level with the enzymatic method. The treatment carried out for 21 days with observation time at day 7, 14 and 21. carrot juice given Doses is 0.52; 1.04, and 2.08 g/20g bw. The results showed that administration of carrot juice at all dose groups can lower blood glucose levels of mice was significantly (P, 0.05) After giving 3 mg/20 g bw alloxan and glucose 195 mg/20 g bw.

Perbandingan Mutu Tablet Ibuprofen Generik Dan Merek Dagang Maria Dona Octavia; Fitriani Fitriani; Firmansyah Firmansyah
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Ibuprofen is a non Steroid Anti-Inflamation Drug (NSAID) and most of Ibuprofen Tablets have been sold with generics name and branded name. This study is done to compare quality of Ibuprofen tablets 400 mg, there were 6 brands of tablet which they had consisted 3 brands of generic tablets and 3 brands of branded name tablets. Determination of quality Ibuprofen tablets could be showed from standard quality of Ibuprofen tablets were based at Farmakope Indonesia and USP. Quality parameter of Ibuprofen tablets included physical tablet evaluation, assay and dissolution profile test. Dissolution profile testing of Ibuprofen tablets was performed by paddle method and measured by Spectrofotometer UV used pH 7.2 phosphate buffer as medium. Assay of tablet was performed by Spectrofotometer UV in NaOH 0.1 N as medium. The test resulted that quality of Ibuprofen generic and branded tablets were same and fulfilled standard quality of Farmakope Indonesia and USP.

Penentuan Kadar Senyawa Fenolat Dan Uji Aktivitas Antioksidan Pada Buah Terung Belanda (Cyphomandra betacea (Cav.) Sendtn) Secara Spektrofotometri Visibel Fithriani Armin; Yuli Yani Dewi; Mahyuddin Mahyuddin
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Levels Determination of phenolic compounds and antioxidant activity assay of eggplant belanda fruit (Cyphomandra betacea (Cav.) Sendtn) with visible spektofotometri has been done. Determination of phenolic compounds performed by the method of Folin ciocalteu, while DPPH is used as an antioxidant. The antioxidant activity is determined by its IC50 value. In this treatment gallic acid used as a comparison. The results showed that the levels of phenolic compounds from the sample extract solution is 0.288845 mg / g; 0.29678 mg / g and 0.28964 mg / g respectively. The antioxidant activity determined by IC50 values, where the value of its IC50 was 240.0811 µg / mL; 204.5010 µg / mL; 196.8531 µg / mL.

Karakterisasi Alginat Dari Ganggang Coklat ( Sargassum crassifolium, Mont ) Dengan Menggunakan CaCl2 14 % Auzal Halim; Yeni Novita Sari; Maria Dona Octavia
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Analysis of the synthetic sweetener sodium saccharin and sodium cyclamate in tea packaging has been done. The content of synthetic sweeteners are identified by color reactions and test microcrystals. The results obtained were compared with the reference standard material. Of the four samples tested, obtained three samples containing sodium cyclamate, while the other samples did not contain sodium cyclamate and sodium saccharin. Levels are determined by sodium cyclamate spektrofoto, ether UV-Vis. Levels of sodium cyclamate were obtained not exceed the maximum limit allowed by the Ministry of Health of the Republic of Indonesia is 0.3% for soft drinks.

Karakterisasi Ekstrak Air Daun Dewa (Gynura pseudochina (L.) DC Dan Penetapan Kadar Flavonoid Totalnya Harrizul Rivai; Femiwati Femiwati; Krisyanella Krisyanella
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

The study about characterization of water extract of Gynura pseudochina (L.) DC leaves has been done. The study reveals the following non-spesific and specific parameters. It’s water content, density, total ash, insoluble acid ash are 78.69 + 0.21 %; 1.08 + 0.0 %; 3.99 + 0.12%; and 0.67 + 0.10% respectively. It’s bacterial count are 4.4 x 103 colonies/g and 2.3 x 102 colonies/g for fungis count. Gynura pseudochina (L.) DC also known as daun dewa in Indonesia. It has Gynura pseudochina Folium Aqueous Liquidum Extractum as it’s identity. The extract is a liquid extract, with swarthy brown colored, specific smells and tasteless. It’s contains secondary metabolites such as alkaloids, flavonoids, saponins and tannins. The content of compounds soluble in water are 20.25 + 0.53% and soluble in ethanol are 8.59 + 0.79%. The total flavonoids content obtained using spectrophotometry UV-Visible method was 0.07 + 0.01 % w/w.

Analisis Pemanis Sintesis Natrium Sakarin Dan Natrium Siklamat Dalam Teh Kemasan Roslinda Rasyid; Melly Yohana; Mahyuddin Mahyuddin
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

It has been studied analysis of the synthetic sweetener sodium saccharin and sodium cyclamate in the tea drink. Synthetic sweetener were identified by color reactions and microcrystalline test. The result were compared with standard substances. Of the four samples examined here are three samples contain sodium cyclamate, while one other sample not find the content of sodium cyclamate and sodium saccharin. Levels of sodium cyclamate in the sample were determined by uv-vis spektofotometer.These levels are below the limit determined by Health Minister’s Regulation of Indonesian Republic which is 0.3 % for the soft drink.

Pengaruh Ekstrak Etanol Herba Ginseng Sumatera (Talinum triangulare (Jacq. ) Willd) Terhadap Aktivitas SGOT Dan SGPT Pada Serum Darah Mencit Putih Jantan Yang Terinduksi Karbontetraklorida Elisma Elisma; Ella Handalia; Helmi Arifin
Jurnal Farmasi Higea Vol 3, No 1 (2011)
Publisher : STIFARM Padang

Influence of the ethanolic extracts of Sumateran ginseng (Talinum triangulare (Jacq.) Willd) on SGOT and SGPT activities in serum of male mice induced CCl4 has been done. The extract was given orally once a day for 14, 21, and 28 days respectively,at various doses 125, 250, and 500 mg/kg BW. The group of mice treated with Na CMC 0,5 % was used as control. The results suggest a possible hepatoprotective potential of the ethanol extract of Talinum triangulare can decrease the SGOT and SGPT activities on male mice induced CCl4.

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