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Jurnal Biomedika dan Kesehatan
Published by Universitas Trisakti
ISSN : 2621539x     EISSN : 26215470     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal Biomedika dan Kesehatan is an official publication of Faculty of Medicine Trisakti University. Jurnal Biomedika dan Kesehatan is a third-monthly medical journal that publishes new research findings on a wide variety of topics of importance to biomedical science and clinical practice. Jurnal Biomedika dan Kesehatan online contains both the current issue and an online archive that can be accessed through browsing, advanced searching, or collections by disease or topic.
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Articles 13 Documents
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Search results for , issue "Vol 5 No 3 (2022)" : 13 Documents clear
Hubungan Asupan Kalsium dengan Intensitas Dismenore Primer pada Remaja Vebby Grace Carolina; Arleen Devita
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.214-220

Abstract

BackgroundPrimary dysmenorrhea is lower abdominal pain happening during menstruation which is not associated with other diseases or pathology, mostly experienced by adolescents around the world, including in Indonesia. Calcium intake is considered to affect decreasing the intensity of primary dysmenorrhea. Lack of calcium can cause muscle spasms and contractions. However, the average daily intake of calcium in adolescents in Indonesia is still below the recommended adequacy rate. This study aimed to assess the correlation between calcium intake and the intensity of primary dysmenorrhea in adolescents. MethodsThis study was done from March 2019 until January 2020; Analyzed the correlation between calcium intake and intensity of primary dysmenorrhea in 62 adolescents. Calcium intake was assessed using a semi-quantitative food frequency questionnaire, while the power of primary dysmenorrhea was assessed using a Visual Analogue Scale questionnaire. ResultsThere were 45.2% of adolescents experienced moderate and severe primary dysmenorrhea. In addition, 51.6% of adolescents experienced less calcium intake, with an average of 804.9 mg per day. The results showed a correlation between calcium intake and the intensity of primary dysmenorrhea (p = 0.000). ConclusionsCalcium intake is related to the intensity of primary dysmenorrhea. While calcium intake in adolescents is still lacking, it is recommended to consume adequate calcium intake.
Hubungan antara Indeks Massa Tubuh dan Lingkar Pinggang dengan Kejadian Hipertensi Sistolik Terisolasi pada Lansia Yasinta Saraswati Hakim; Setyoko Setyoko; Yanurita Tursinawati
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.182-191

Abstract

BackgroundGlobally, it is estimated that 15% of the elderly had isolated systolic hypertension (ISH). ISH in the elderly may occur because of the aging process or other risk factors, such as obesity. Obesity is divided into total obesity which is measured by body mass index (BMI), and abdominal obesity which is measured by waist circumference (WC). The difference in these measurement parameters made this study aim to determine the relationship between BMI and WC with the incidence of ISH in the elderly. MethodsThe study was an analytical observational cross-sectional method and used a consecutive sampling technique with the samples aged ≥ 60 years old that had ISH. The research measured blood pressure, weight, height, and waist circumference. The data was analyzed by Rank Spearman test for the relationship between BMI with the incidence of ISH and Chi-Square test for the relationship between waist circumference with the incidence of ISH, with α values for both tests being 0,05. ResultsThe samples in this study were 110 elderlies with the most criteria being young elderlies (60%), female gender (67,3%), work as farm worker/farmer (41,8%), ISH grade I (66,4%), obesity (36,4%), and abdominal obesity (54,5%). There was no relationship between BMI with the incidence of ISH in the elderly (p= 0,827) but had a relationship between waist circumference with the incidence of ISH in the elderly (p= 0,001). ConclusionsBMI as an indicator of total obesity is not associated with the incidence of ISH in the elderly, but waist circumference as an indicator of abdominal obesity shows a relationship with the incidence of ISH in the elderly.
Hubungan Beban Angkut Terhadap Kejadian Kifosis Pada Buruh Panggul Tiffany Gita Yunilia Sari; Nuryani Sidarta
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.192-202

Abstract

BackgroundOccupational diseases that are often found in the porter (transport worker) are related with the changes in the structure of the spine. Work load, length and duration of work are factors that affect the spine curve. This study aims to see whether there is a relationship between those factors with the incidence of kyphosis among the workers. MethodsThe study used an observational study with a cross-sectional design that included 51 male workers aged 15-65 years in Sumbawa Regency. Sample selection is done in consecutive random sampling. Workers who had conditions such as a history of spinal surgery, spinal fractures, spinal tumors, spinal infections and osteoporosis were not included in the study. The curve of thoracic kyphosis is measured by flexible ruler. The calculation of the degree uses a standard and predetermined kyphosis index formula. Data on carrying loads, duration of work per day and length of work is obtained from the results of questions and answers with workers. The Fisher test was used as a statiscal analysis with a p value <0.05. ResultsIn this study, 60.8% of the porter had worked for more than 10 years and most had a carrying load of > 40 kg with the duration of work more than 8 hours per day. Measurements of the curvature of the vertebrae found that 35 people (68.6%) had normal curves followed by 16 people (31.3%) had kyphosis. Statistical test results with Fishertest found a significant relationship between carry load (p=0.003), duration of work (p=0.047) and working period (p=0.037) with kyphosis. ConclusionsThere is a significant relationship between the load of transport and the incidence of kyphosis in transport workers. The length of work per day and working period also have a significant influence on the efficacy of kyphosis.
Hubungan antara Kontak Erat dengan Anggota Keluarga Kasus Terkonfirmasi dan COVID-19 pada Anak di Puskesmas Panjatan II Kulon Progo Anggita Bintari Handayaningrum; Tubagus Ferdi Fadilah
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.161-170

Abstract

BackgroundIt is estimated that the positive infection rate of COVID-19 in Indonesia is 4.261.412 cases confirmed. Indonesian Pediatric Society noted that since May 2021, cases of pediatric COVID-19 infection have been rising; it is related to many factors such as host immunity, nutrition, sociodemographics, and close contact. Our research evaluated the closed contact factor with confirmed cases in a family member or household contact and pediatric COVID-19 infection, the incidence of pediatric COVID-19, the association between closed contact with confirmed cases in family members and pediatric COVID-19 infection. MethodsOur research uses the observational analytics method, cohort retrospective design, based on medical records, 242 samples collected, period November 2020-November 2021, with sampling technique consecutive nonrandom sampling; our inclusion criteria are 0-18 years old, have positive or negative antigen swab or RT-PCR, wholly followed up by the health center. ResultsUsing chi-square in SPSS application, our research stated Mother and Father are the main sources of household contact transmission, children 12-18 years old, women sex are the highest number the incidence, statistical result p<0,05. ConclusionsAccordingly, there is an association between closed contact with confirmed cases in family members and pediatric COVID-19 infection.
Fenomena Gejala Pilek paling Sering pada Pasien COVID-19 Joekly Wahidan Muharaam; Diana Samara
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.136-143

Abstract

BackgroundCOVID-19 is an infectious disease caused by SARS-CoV-2, a new coronavirus that has never been identified in humans that causes various symptoms. Symptoms of COVID-19 that are quite often found are cough, runny nose, fever. Antigen rapid test is an examination with high sensitivity and specificity, often used in COVID-19 detection. This study aims to determine the relationship between cough, cold, and fever symptoms with positive results of COVID-19 antigen rapid test. MethodsThis study used cross-sectional design using medical records. The variables assessed were cough, cold, fever, and the results of COVID-19 antigen rapid test. Data analysis was performed using chisquare test and logistic regression test with significance level of p<0.05. ResultsSubject are mostly are 31-45 years old and female. Subjects had symptoms of cough (88.2%), fever (80%), and runny nose (60%). The results of the COVID-19 rapid test antigen were found to be more reactive (80%). The distribution of reactive results of the COVID-19 rapid antigen test was 86.7% in cough, 92.2% in colds, and 91.2% in fever. There was a significant relationship between cough (p=0.000), runny nose (p=0.001), and fever (p=0.000) with reactive results of the COVID-19 rapid test antigen. Patients with cold symptoms have an 8.67 times greater risk of reactive COVID-19 antigen rapid tests. ConclusionsThere is a relationship between symptoms of cough, runny nose, and fever with reactive results in patients aged 17 years and over. Complaints of a cold have a higher risk of reactive results on the COVID-19 rapid test antigen examination compared to cough and fever. This means that patients with colds need to be more aware of being infected with COVID-19.
Hubungan Asupan Vitamin B6 dengan Sindrom Pramenstruasi pada Siswi SMP Carissa Maharani Amry; Purnamawati Tjhin
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.144-152

Abstract

BackgroundMany women complain of uncomfortable symptoms a few days before menstruation in the form of emotional problems to discomfort in the abdominal area, this condition is called premenstrual syndrome. Lack of nutrients, one of which is vitamin B6, is a risk factor for premenstrual syndrome. This study was conducted to assess the relationship between vitamin B6 intake and premenstrual syndrome in junior high school students. MethodsThe study used an analytical observational method with a cross-sectional design, in 162 students of SMPN 75 Jakarta, which was taken with cluster random sampling and simple random samplingtechniques. Measurement of the incidence of premenstrual syndrome was carried out using sPAF questionnaires and vitamin B6 intake using SQ-FFQ questionnaires. The data from the study were analyzed using the chi-square test. The research was conducted after obtaining the approval of the number ethics 7/KER-FK/II/2022. ResultsThe results showed that female students who experienced premenstrual syndrome were mostly aged 15-16 years (20.8%), had menarche at the age of under 12 years (16.4%), did less exercise (15.6%), had a body mass index (BMI) in the category of excess nutrition (25.0%), and consumed foods that contained enough vitamin B6 (15.0%). The results of the bivariate analysis between free and dependent variables found no meaningful relationship between premenstrual syndrome and age (p = 0.054), menarche age (p = 0.630), exercise (p = 0.726), BMI (p = 0.131), and vitamin B6 intake (p = 1.000). ConclusionsThere was no relationship between vitamin B6 intake, sociodemographic characteristics (age, menarche age), exercise, and body mass index (BMI) and premenstrual syndrome.
Laporan Kasus: Diagnosis dan Tatalaksana Meningoensefalitis Tuberkulosis dan Ensefalitis Toksoplasma pada Pasien dengan HIV Positif Della Septa; Yudhisman Imran; Ronny Yoesyanto Pragono
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.221-227

Abstract

Background Tuberculous meningoencephalitis (TBME) and toxoplasma encephalitis (TE) are the most frequent cerebral opportunistic infections in positive HIV patients in developed countries. This study aims to determine a presumptive diagnosis of TBME and TE based only on clinical, CD4-count, and radiology features and to attend suitable early treatment for better patient outcomes. Case Description A 40-year-old presented to the emergency unit of dr. Mintohardjo Naval Hospital with decreased consciousness. History of positive HIV status, pulmonary tuberculosis for six months and anti-tubercular-treatment (ATT) drop-out. The GCS was E2M5V2, lung crackles, nuchal rigidity, positive Babinski reflex, and duplex hemiparesis. CD4-count: 4 cells/mm3. Multiple hypodense lesions, “finger-like-oedema”, featured on non-contrast head CT-scan. A lumbar puncture was not performed. Treatment of TBME included an ATT regimen, pyridoxine, cotrimoxazole, anti-oedema, and TE treatment included clindamycin and pyrimethamine. Based on the clinical and radiological diagnosis of TBME (nuchal rigidity, history of ATT drop-out, multiple hypodense lesions on CT-scan) and TE (altered mental status, duplex hemiparesis, CD4-count, “finger-like-oedema” projections on CT-scan), ATT and TE treatment were given for ten days. There were significant clinical improvements by GCS E4M6V3, negative nuchal rigidity after being treated early by ATT and TE treatment. Conclusions Presumptive Diagnosis of TBME and TE in HIV patients can be determined only based on clinical, CD4-count, and radiology examination. However, there are significant clinical improvements in giving ATT along with TE treatment immediately in positive HIV patients.
Derajat Miopia Berhubungan dengan Ketebalan Kornea Sentral pada Usia 18-40 Tahun Elizabeth Ravinka Rossabel ER; Kartini Kartini
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.203-213

Abstract

BackgroundThe central corneal thickness (CCT) is important in assessing the cornea’s condition and correlates with refractive errors in which myopic eyes have the thinnest central cornea. Based on the 2018 Riskesdas, 2,133,017 people suffer from severe low vision, of which 42% were connected to refractive errors. One of the treatments for myopia is to perform LASIK surgery, but complications may occur during its process. One of the risk factors for post-LASIK complications is a CCT of less than 500 microns. This study aimed to assess the association between the degree of myopia and CCT at 18-40 years old. MethodsThis study was a cross-sectional design with data taken from 124 medical records from the Gading Laser Eye Center with subjects aged 18-40 years consisting of 88 males and 36 females. Variables collected were initials, age, gender, CCT, and degree of myopia. Data analysis was carried out using the Chi-Square test with a significance level of p<0.05. ResultsThe age category was 18-28 (87.9%), dominated by males (71.0%). Most degrees of myopia were mild (48.4%), and CCT was dominated by thinning corneas (63.7%). Data analysis based on the Chi-Square test regarding the degree of myopia and CCT showed a significant association (p=0.001). ConclusionsThis study showed an association between the degree of myopia and CCT at the age of 18-40 years.
Konsentrasi dan Kebugaran Meningkatkan Produktivitas Kerja Ivo Kristina Dalimunthe; Fransisca Chondro
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.171-181

Abstract

Background Work productivity is important for a company to maximise company performance. Work productivity can be affected by concentration and physical fitness. Concentration is the ability to focus attention on work. Meanwhile, physical fitness is the ability of the body to perform activities without exhaustion. This study was conducted to determine the value of the relationship between concentration, fitness and employees' work productivity. MethodsThis study used a cross-sectional design. The subjects were employees of Cooperative Service Bandung, and the subject selection used non-probability sampling. Army Alpha Test measured concentration. A non-exercise fitness test assessed the level of physical fitness. Work productivity was assessed using a work productivity questionnaire. Data analysis was performed using SPSS version 20 with univariate analysis and bivariate Chi-square test. A total of 130 respondents participated in this study. ResultsThe Chi-square test results showed a significant relationship between concentration level and work productivity (p=0.001) and a relationship between the level of fitness and work productivity (p=0.031). ConclusionsThus concentration and physical fitness lead to work productivity.
Review: Pengaruh Nanopartikel ZnO sebagai Antimikroba pada Multidrug Resistance Klebsiella Pneumonia Nuha Kudaer; Mohsen Hashim Risan; Emad Yousif; Mohammed Kadhom; Rasha Raheem; Nany Hairunisa; Husnun Amalia
Jurnal Biomedika dan Kesehatan Vol 5 No 3 (2022)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2022.v5.236-242

Abstract

Klebsiella pneumoniae (K. pneumoniae)is a common microorganism for different infections, including respiratory, urinary tract, and biliary diseases, where immunocompromised individuals are directly affected by this bacterium. However, with the emergence of hypervirulent strains, individuals,whether healthy or immunocompetent, are equally susceptible to K. pneumoniae infections. This problem is diagnosed by the wide spreading of multidrug-resistant bacteria in the environment with multiple resistance mechanisms, which are the main challenges for an effective treatment. This put physicians in an inflexible confusion because of the limitation of medical treatment options. Among many remedy substances, zinc oxide (ZnO) nanoparticles (NPs) showed remarkable antibacterial properties versus many Gram-positive and Gram-negative bacteria. This work focuses on presenting the influence of these NPs on the expression of genes in charged in generating the K. pneumoniae capsule. Furthermore, perspectives for applying ZnO NPs in clinical practices are also discussed. As the in vivo studies show a powerful impact of ZnO on bacteria, it is anticipated that this method of treatment will be utilized by hospitals.

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