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Dina Keumala Sari
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Sumatera Medical Journal
Published by Universitas Sumatera Utara
ISSN : 26229234     EISSN : 26221357     DOI : 10.32734
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 169 Documents
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Analysis of Risk Factors Associated with Maskne in the Era of the COVID-19 Pandemic Az-Zahra, Salsabila; Jusuf, Nelva Kamilah
Sumatera Medical Journal Vol. 6 No. 1 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i1.8015

Abstract

Background: The necessity to always use a mask in the era of the COVID-19 pandemic has given rise to a new term called maskne. Maskne is the appearance of acne that is triggered by wearing a mask. It usually occurs specifically in the area covered by the mask, focused on the cheeks, chin, and nose. Objective: This study aims to determine the risk factors associated with the occurrence of maskne. Methods: A cross-sectional study was conducted on the Faculty of Medicine students, Universitas Sumatera Utara class 2018. This study uses primary data from questionnaires and observation of respondents' face photos. Results: Based on statistical analysis, 99 out of 221 respondents (44.8%) experienced maskne. Bivariate analysis shows p-values <0.05 for gender, duration of mask use, and previous acne history. On the other hand, it was obtained p-value >0.05 for the type of mask and mask changing habit. Conclusion: Based on multivariate analysis, the p-value <0.05 for gender indicates that gender is the most dominant risk factor in the incidence of maskne. Furthermore, there is a significant association between gender and the occurrence of maskne. Females are twice as likely to experience maskne.
Identification of Soil-Transmitted Helminths in Soil of Sheep Farm in Manggis Village, Serbajadi District, Serdang Bedagai Regency Tesalonika, Natasya Cornelia; Carolina Panggabean, Yoan; Panggabean, Merina; Sugih Arto, Nindia
Sumatera Medical Journal Vol. 6 No. 1 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i1.8039

Abstract

Background: More than one and a half million of whole world population are infected by Soil Transmitted Helminths. The most common types of Soil Transmitted Helminths found in human are Ascaris lumbricoides, Trichuris trichiura and Hookworm (Necator americanus and Ancylostoma duodenale). Soil Transmitted Helminths infections are usually found on individuals with poor hygiene, low socioeconomic status, and high risk occupations, such as sheep farmer. Sheep farming in Indonesia is generally a small-scale farm with modest technology. Livestock herding on the pasture may cause the livestock to consume Soil Transmitted Helminths-contaminated grass. Soil is the medium for the maturing of Soil Transmitted Helminths fertilized egg into infective form. Modest handling aspect and poor sanitation allow Soil Transmitted Helminths to be found in farm soil. Objective: To identify Soil Transmitted Helminths in the soil of a sheep farm in Manggis Village, Serbajadi District, Serdang Bedagai Regency. Methods: This observational descriptive study was conducted with cross-sectional approach. 100 of soil samples were collected per 8 square meters through quota sampling from a sheep farm in Manggis Village, Serbajadi District, Serdang Bedagai Regency. The data was collected by carrying out flotation technique in laboratory.. Results: Soil Transmitted Helminths eggs were discovered in 17 (17%) out of 100 samples, Hookworm eggs in 14 samples (14%), and Ascaris lumbricoides eggs in 5 (5%) samples. Conclusion: There are Soil Transmitted Helminths in soil of the sheep farm in in Manggis Village, Serbajadi District, Serdang Bedagai Regency.
Association between Serum Alp Levels and Pre- Operative LDH towards Clinical Prognosis of Osteosarcoma Patients in H. Adam Malik Hospital, Medan Christoffel Tampubolon , Gerhard; Siregar, Otman; Andriandi
Sumatera Medical Journal Vol. 6 No. 1 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i1.8991

Abstract

Background: Osteosarcoma remains a challenging disease, especially for young patients, due to its tendency to spread to the lungs and resist treatment. Identifying reliable markers at diagnosis could help doctors start more effective treatment earlier and improve patient outcomes. Two blood markers, ALP and LDH, may offer insight into a patient’s prognosis. Objective: This study explored whether pre-surgery levels of ALP and LDH could predict survival in osteosarcoma patients. Methods: Researchers reviewed medical records of patients diagnosed with osteosarcoma at RSUP Haji Adam Malik Medan from 2015 to 2017. This retrospective study included those who met the necessary criteria and had complete data. Results: The study found no strong evidence linking ALP or LDH levels to five-year survival. ALP had a very weak negative correlation with survival (r = -0.019), while LDH showed a weak positive correlation (r = 0.093). Median ALP was 212 U/L; LDH was 489 U/L. Sensitivity and specificity were moderate for both markers. Conclusion: There is no significant relationship between ALP and LDH with five-year survival.
Clinicopathological Characteristics of Invasive Breast Carcinoma on PDL-1 Immunohistochemical Expression in H. Adam Malik Hospital Medan Prawira Lesmana , Daniel Kristian; Rifsal Siregar, Denny; Hermansyah, Dedy
Sumatera Medical Journal Vol. 6 No. 1 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i1.9061

Abstract

Background: Immune biologic markers that can predict clinical response to anti-PD-1/PD-L1 therapy are needed to identify and validate tumor immunotherapy studies. High PD-L1 expression is associated with increased clinical response in patients with various types of cancer treated with inhibitors of the PD-1/PD-L1 pathway. Objective: The researcher wanted to see the clinicopathological characteristics of invasive breast carcinoma according to the immunohistochemical expression of PD-L1. Methods: This study is a descriptive study with a cross-sectional, retrospective approach by looking at secondary data from the medical records of the Department of Surgery, Haji Adam Malik Hospital from January 1, 2019, to December 31, 2021. Results: Immunohistochemical expression of PD- L1 was positive in 76.6% of invasive breast carcinomas and negative in 23.3% of invasive breast carcinomas. Immunohistochemical expression of PD-L1 was positive in non-specific IBCs that predominated in every molecular subgroup of breast carcinoma. Conclusion: Tumours can show positive or negative PD-L1 expression through several biological processes with different functional significance, namely the genetic mechanism of constitutive or oncogene-induced PD-L1 expression, PD-L1 expression induced in T cells, and absence of PD-L1 expression. Due to the absence of T cells and genetic events that block the expression of PD-L1 despite T cell infiltration.
Correlation between Pregnant Women’s Anxiety Level and Their Decision toward COVID-19 Vaccine Acceptance Hanna, Kyrie; Indah Sari, Mutiara; Hidayat, Hidayat; Pase, M. Aron
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.10963

Abstract

Introduction: High number of COVID-19 cases cause various effects, namely increased anxiety and depression in pregnant women, who are susceptible to transmission. To prevent further transmission, a vaccination policy was implemented which then elicited various responses. Low percentage of pregnant women’s willingness to be vaccinated was found. This happened because of anxiety and hesitancy towards COVID-19 vaccine among them. Objective: Knowing the correlation between the level of anxiety in pregnant women towards COVID-19 vaccine and the decision to accept COVID-19 vaccine at Abadijaya Public Health Center, Depok. Methods: Analytic with cross sectional method is used. Population and sample of this study were 96 pregnant women who visited Abadijaya Public Health Center, Depok. Results: Analysis conducted using chi squared and fisher’s exact test shows majority of pregnant women do not experience symptoms of anxiety (50%), no correlation between age, gestational age, gravidity, occupation and education level on the decision to accept COVID-19 vaccine, and correlation between pregnant women’s anxiety levels and the decision to accept COVID-19 vaccine was found (p value = 0.000). Conclusion: There is a correlation between anxiety levels in pregnant women towards COVID-19 vaccine and the decision to accept COVID-19 vaccine at Abadijaya Public Health Center, Depok.
Prevalence and Correlated Factors of Urinary Incontinence in Geriatrics Purba, Adriel John Junior; Mirsya Warli, Syah; Dharma Kadar, Dhirajaya; Charani Eyanoer, Putri
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11030

Abstract

Background: Urinary incontinence is involuntary or uncontrollable urine passing. This is very disruptive, it causes a lot of problems and is often seen as an embarrassing thing. The prevalence of urinary incontinence was found to increase with age. Objective: This research aimed to determine the prevalence and factors associated with the incidence of urinary incontinence in geriatric patients at the Haji Adam Malik General Central Hospital and the University of North Sumatera Hospital. Methods: This type of research is an analytic observational study with a cross-sectional design. The research sample is determined by consecutive sampling technique using a questionnaire as primary data. Results: Out of 100 respondents, 22 geriatric patients experienced urinary incontinence, with the majority experiencing moderate severity and stress urinary incontinence. Based on bivariate analysis using chi-square found gender (p=0.617), age (p=0.617), overweight (p=<0.01), diabetes mellitus (p=<0.01), hypertension (p=0.01), history of chronic cough (p=<0.01), history of pelvic surgery (p=<0.01), and history of vaginal delivery (0=0.055). Conclusion: In this study, the risk factors associated with urinary incontinence are overweight, diabetes mellitus, hypertension, and a history of chronic cough while risk factors that are not found to be associated in this study are age, sex, and history of vaginal delivery.
Correlation Between Blue Light Exposure from Digital Device Screens and Sleep Quality Among Students in the Faculty of Medicine, Universitas Sumatera Utara Class of 2019 Lubis, Muhammad Rizki Zaini; Kadri, Alfansuri
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11051

Abstract

Background: The use of information and communication technology facilities such as cellphones, laptops, computers, and other information facilities is really needed. From several previous studies it was noted that blue light has an impact on sleep quality, as we already know sleep quality is one of the foundations of health. Objective: The aim is to determine the relationship between blue light exposure on digital device screens and sleep quality, knowing the level of blue light exposure and sleep quality. Methods: This research is an analytical study with a cross-sectional design, namely a type of research in which the measurement of the variables is carried out simultaneously at one time. Results: Of the 150 study subjects, there were 64% women, 36% men. Age, 1.30% were 19 years old, 18.70% were 20 years old, 58% were 21 years old, 20% were 22 years old, 2% were 23 years old. Blue light exposure, bad 94%, good 6%. Sleep quality, bad 87.30%, good 12.70%. The relationship between blue light exposure and sleep quality obtained p-value <0.01 and coefficent r is 0.663. Conclusion: there is significant relationship between blue light exposure on digital screen device and sleep quality of student.
Knowledge and Behavior of the Tembung Village Community about Sunscreen to Prevent Melanoma Ali, M. Fakhri; Utama Pohan, Pimpin; Prayugo, Bambang; Rahmadhany, Heru
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11092

Abstract

Background: Indonesia is one of the tropical countries in the world that is illuminated by the sun all year round. High sun exposure requires Indonesian people to be more concerned about skin protection, especially melanoma. The risk factor for melanoma is exposure to UV radiation so melanoma can be prevented by reducing exposure to UV rays, one of them by using sunscreen. The use of sunscreen with SPF 15+ every day can reduce the risk of developing melanoma by 50%. Objective: This study aims to obtain information about the level of knowledge and behavior of people in Tembung about the use of sunscreen to prevent melanoma. Methods: The research design used is descriptive research using a cross-sectional study. The Data was obtained through the distribution of online questionnaires with 100 people. Furthermore, the data obtained will be processed using SPSS. Results: 41 people had sufficient knowledge about melanoma, 67 people had less knowledge about sunscreen, and 38 people had good behavior. Conclusion: Most of people in Tembung have sufficient knowledge about melanoma, lack knowledge about sunscreen, and have a good behavior in using sunscreen.
Association of Multiple Trauma Referral Distance with Mortality in H. Adam Malik General Hospital Medan Nasution, Ahmad Akbar; Irsyam, OK Ilham Abdullah; Siregar, M. Hidayat
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11196

Abstract

Background: The increasing distance from the location of the trauma to the trauma center can cause an increase in mortality. The farther the distance from the trauma center, the higher the mortality of trauma patients. Geographical variations in care may contribute to the effect of the relationship between distance and mortality in trauma patients. Objective: This study wanted to determine the relationship between multiple traumas referral distances and mortality based on ISS at Haji Adam Malik General Hospital Medan. Methods: The study design was an analytic study with the independent variable being the patient's referral distance and the dependent variable being the predictor of mortality in multiple traumas. The approach used in this research design is a retrospective approach. Results: The mean age of the patients was 31.08±17.82 years. Most of the patients were male, most died, and the average referral distance was 79.67 ± 63,244 km. The majority of the ISS scores were 16. The relationship between referral distance and death in the hospital has a P value of < 0.05. Conclusion: There is a significant relationship between multiple trauma patients' referral distance and hospital mortality.
Diets That Have Potential to Stimulate the Hypothalamic-Pituitary-Adrenal (HPA) Axis in Sprague Dawley Rats Khairil Azwan; Mona, Resni; Firdous, Jannathul; Rosie David, Pamela; Keumala Sari, Dina; Muhammad, Noorzaid
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11650

Abstract

Background: The pituitary gland is the master gland regulating body hormones. From the anterior pituitary’s corticotrophs, adrenocorticotrophic hormone (ACTH) is secreted and influences corticosterone production in rodents via the hypothalamic–pituitary–adrenal (HPA) axis. ACTH and corticosterone are commonly used as hormonal stress markers. Disturbances in ACTH and corticosterone are seen in diseases like Addison’s disease, Cushing’s syndrome, and metabolic syndrome. Objective: To observe which diet induces the most and least stress on Sprague Dawley rats’ physiology. Methods: Thirty-five Sprague Dawley rats were divided into five groups (n=7) and given different diets (control, high-fat, high-protein, high-sugar, and high-starch) with tap water ad libitum. After eight weeks, blood samples were collected and serum separated. ACTH and corticosterone were extracted, purified, identified, and quantified using High-Performance Liquid Chromatography (HPLC) with photodiode array (PDA) analysis. Results: High-sugar diet led to the highest ACTH blood level. Both high-fat and high-sugar diets showed the highest corticosterone peaks. Conclusion: Consumption of high-fat and high-sugar diets for eight weeks is suggested to induce physiological and metabolic stress in Sprague Dawley rats, as evidenced by HPA axis activation.

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