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Interdental Jurnal Kedokteran Gigi (IJKG)
Published by Universitas Mahasaraswati
ISSN : 19799144     EISSN : 26855208     DOI : 10.46862
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Medicine & Pharmacology Public Health
Interdental Journal is a scientific published and supported by Faculty of Dentistry Universitas Mahasaraswati Denpasar and published Three Times a year. The submission process opens throughout the year. All submitted manuscript will be screened with double-blind peer review and editorial decision before the manuscript was accepted to be published. Interdental Journal present original research articles, review articles, and case report that sounding the innovation and recent development in dentistry including oral biology; dental material science and technology; oral and maxillofacial surgery; pedodontics; dental public health, epidemiology, preventive and community dentistry; conservative dentistry; periodontics; prosthodontics; orthodontics; oral medicine; dentomaxillofacial radiology; forensic dentistry as well as with their development through interdisciplinary and multidisciplinary approach. We accept publication in Indonesian or English.
Arjuna Subject : Kedokteran Gigi - Kedokteran Gigi (Lain-Lain)
Articles 375 Documents
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Increase in Interleukin-6 Levels in the Gingiva of Male Wistar Rats Induced by Porphyromonas gingivalis Sardi, Ni Wayan Arni; Yasa, Wayan Putu Sutirta; Linawati, Ni Made
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.12869

Abstract

Introduction: Interleukin-6 (IL-6) in healthy gingiva contributes to regulating the immune response and tissue homeostasis. Exposure of lipopolysaccharide (LPS) from the Porphyromonas gingivalis bacteria (P. gingivalis) in periodontal tissues can influence the role of IL-6, shifting it from a tissue homeostatic agent to a pro-inflammatory cytokine. This study aimed to determine the levels of IL-6 in the gingiva of male Wistar rats induced by P. gingivalis bacteria. Material and Methods: This research uses a posttest-only control group design. Thirty-two male Wistar rats were divided into two groups, each consisting of sixteen rats. The control group consisted of 16 male Wistar rats that were not induced with bacteria. The experimental group consisted of sixteen male Wistar rats with the induction of P. gingivalis bacteria. Results and Discussions: The results showed that the IL-6 levels in the healthy male Wistar rat group were lower than the IL-6 levels in the male Wistar rat group induced with P. gingivalis bacteria. More exposure to LPS due to the induction of P. gingivalis bacteria causes increased permeability of the gingival mucosal barrier, which can shift the tissue balance towards a pro-inflammatory state, resulting in increased production of IL-6. Conclusion: IL-6 levels increased in the gingiva of male Wistar rats induced with P. gingivalis bacteria.
Application Of Edible Coating Chitosan and Nanochitosan Shrimp Shells on Heat-Polymerized Acrylic Resin Based on Water Absorption Koesoemawati, Ria; Sapitri, Kadek Dwi Dessy; Wirayuni, Kadek Ayu
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.12910

Abstract

Introduction: The base material commonly used for removable dentures is heat-polymerized acrylic resin. Its weakness is water absorption, causing dimensional changes, discoloration, and effects on mechanical properties such as transverse strength, hardness, and biocompatibility. Shrimp shell chitosan, a natural biopolymer, can form a thin film coating and has the potential to be used as an edible coating. The purpose of this study was to examine the effect of applying edible chitosan and nanochitosan coatings from shrimp shells to heat-cured acrylic resin in inhibiting water absorption. Materials and Methods: The research design was a true experimental laboratory with a posttest-only control group design. Thirty plates measuring 60X10X2.5 mm were divided into 5 groups, namely 1 control group without coating (distilled water) and 4 treatment groups with 2% chitosan, 3% chitosan, 2% nanochitosan, and 3% nanochitosan Aldrich® shrimp shells. The coating was applied by immersion for 5 minutes and dried for 1 hour for all treatment groups. Water absorption was tested by immersion in distilled water for 7 days at a temperature of 37±2 °C, calculated according to the formula in ISO 4049. Results and Discussion: One-way ANOVA analysis showed significant differences (p<0,001). The LSD post-hoc test showed that all treatment groups differed significantly from the control group (p=0.001). Meanwhile, there were no significant differences between the chitosan and nanochitosan treatment groups (p>0.05). Conclusion: It can be concluded that the application of 2% and 3% edible chitosan and nanochitosan coatings from shrimp shells can inhibit water absorption in a heat-polymerized acrylic resin base.
The Effect of Calcium Hydroxide Particle Size on the Viability of NIH3T3 Fibroblast Cells Sidiqa, Atia Nurul; Nursaena, Maysa; Zakaria, Myrna Nurlatifah
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.12911

Abstract

Introduction: Calcium hydroxide [Ca(OH)₂] is a widely used intracanal medicament due to its antimicrobial properties and its ability to stimulate hard tissue formation. Ca(OH)₂ plays a crucial role in endodontic therapy, primarily for its antimicrobial properties and its potential to facilitate reparative dentin formation. Its cytotoxic effects, particularly in relation to particle size, require in-depth investigation. This study aims to evaluate the cytotoxicity of calcium hydroxide with varying particle sizes on cultured fibroblast cells, thus providing insights into the implications of particle size on the biological responses elicited by calcium hydroxide. Material and Methods: This study was an in vitro experimental research aimed to evaluate the effect of Ca(OH)2 particle size on the viability of NIH3T3 fibroblast cells. Three forms of Ca(OH)2 were used: nanoparticles, microparticles, and commercial Ca(OH)2 as the positive control. Each sample was mixed with distilled water to form a paste and applied to cell cultures, while untreated cells served as the negative control. Cytotoxicity was assessed using the MTT assay after 24 hours of exposure, and cell viability was calculated relative to the control. Data were analyzed using the Kruskal Wallis and Mann Whitney tests with a significance level of α = 0.05. Results and Discussions: The nanoparticle Ca(OH)2 group showed the lowest cell viability (1.8%), which was significantly lower than that of the microparticle group (3.0%) and the commercial Ca(OH)2 group (5.0%) (p = 0.1). All Ca(OH)2 groups exhibited a high level of cytotoxicity, with cell viability below 20%, categorized as highly toxic. These results indicate that nanoparticle Ca(OH)2 may increase the risk of cellular toxicity. Conclusion: These findings emphasize the importance of considering particle size in the use of Ca(OH)2 as an intracanal medicament. Further biocompatibility evaluations are required to balance its antibacterial effectiveness with the safety of surrounding tissues.
In Vitro Evaluation of Turmeric Extract (Curcuma domestica) Antibacterial Activity against Staphylococcus aureus Causing Dental Abscess Astuti, Ni Putu Widani; Pratama, I Wayan Agus Wirya; Yudistian, Ilma
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.12996

Abstract

Introduction: Dental abscess is a common odontogenic infection characterized by pus accumulation due to an inflammatory response to microorganism invasion. Staphylococcus aureus is a major opportunistic pathogen frequently found in periapical abscesses and endodontic infections. Increasing bacterial resistance to conventional antibiotics has become a global health concern. Turmeric (Curcuma domestica) possesses antibacterial activity attributed to curcumin and phenolic compounds. Materials and Methods: This experimental laboratory study with a post-test only control group design was conducted at the Microbiology Laboratory, Faculty of Dentistry, Airlangga University in October 2023. Turmeric extract at 50%, 75%, and 100% concentrations was tested against Staphylococcus aureus isolates using the disc diffusion method on Mueller-Hinton Agar. Data were analyzed using One-Way ANOVA and LSD post-hoc test (α = 0.05). Results and Discussion: Phytochemical screening detected six active compounds: saponins, phenols, steroids, alkaloids, flavonoids, and tannins. Turmeric extract at 100% produced the highest inhibition zone of 16.38 mm, compared to 23.20 mm for the positive control (0.2% chlorhexidine). ANOVA analysis showed significant differences among groups (F = 277.78; p < 0.05), with a positive correlation between increasing extract concentration and antibacterial effectiveness. Conclusion: Turmeric rhizome extract at 50%, 75%, and 100% concentrations demonstrates significant antibacterial activity against Staphylococcus aureus, with effectiveness increasing proportionally to concentration, showing potential as a natural antibacterial alternative therapy in dentistry, especially in instances of dental abscesses.
Content of Volume 21 Issue 3 December 2025
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Page 38 of 38 | Total Record : 375

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