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Contagion: Scientific Periodical Journal of Public Health and Coastal Health
Published by Universitas Islam Negeri Sumatera Utara
ISSN : -     EISSN : 26850389     DOI : 10.30829/contagion
Core Subject : Health,
Health Professions Public Health
Contagion: Scientific Periodical Journal of Public Health and Coastal Health, A Scientific Periodic Journal of Public Health published by the Public health Study Program of The Faculty of Public Health UINSU Medan. This Journal prioritiez the collaboration of lecturers and students with scope of the discussion is about Public Health, Health and Islam, and Coastal Health. This Journal is published twice, published on June and December.
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Articles 465 Documents
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Effects of Online Prenatal Yoga on Anxiety Level and Quality of Life Among Third Trimester Pregnant Women in North Cikarang District Bambang Amelia Fajriati Urbaningrum; Akhmad Yogi Pramatirta; Puspa Sari; Hadi Susiarno; Vita Murniati Tarawan; Shelly Iskandar
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 3 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i3.26236

Abstract

The third trimester of pregnancy, is a vulnerable period for anxiety due to physical changes, sleep disturbances, hormonal shifts, and concerns about childbirth. According to statistics from the WHO, up to 10% of pregnant women and 13% of postpartum women suffer from mental health problems, among which the prevalence of prenatal anxiety is as high as 15%. These conditions may impair maternal and fetal health and reduce quality of life. Prenatal yoga, especially movements targeting the psoas muscle, has been proposed to alleviate stress and anxiety. This study aimed to examine the effects of prenatal yoga on anxiety levels and quality of life among women in the later stages of pregnancy in North Cikarang District. A total of 64 participants took part in this quasi-experimental study. They were allocated into two groups based on health centers: an intervention group (n=32), which received eight online prenatal yoga sessions, and a control group (n=32), which continued routine antenatal care. To assess the impact of the intervention, anxiety levels were evaluated both before and after the treatment using the “Perinatal Anxiety Screening Scale (PASS)”, and quality of life was measured using the “World Health Organization Quality of Life Scale-Brief (WHOQOL-BREF)”. Data analysis was performed using the Wilcoxon and Mann-Whitney statistical tests. The findings revealed a significant decrease in anxiety levels among participants in the intervention group compared to those in the control group (p < 0.001). Furthermore, participants who engaged in prenatal yoga experienced notable enhancements in their quality of life, encompassing physical, psychological, social, and environmental aspects (p < 0.001). Overall, the study concludes that prenatal yoga serves as an effective approach to alleviating anxiety and enhancing the overall quality of life for women in the later stages of pregnancy in North Cikarang District Keywords: Anxiety, Third-Trimester Pregnancy, Quality of Life, Pregnant Women, Online Prenatal Yoga
Reduction of VEGF Levels by Phaleria macrocarpa Flavonoids in an Endometriosis Mouse (Mus musculus) Model Amina Diarsy; Fany Hardiati Amalia; Sutrisno Sutrisno; Tatit Nurseta; Safrina Dewi Ratnaningrum
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 3 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i3.25355

Abstract

Endometriosis occurs when endometrial-like cells proliferate at ectopic sites outside the uterus. The advancement of endometriotic lesions is strongly influenced by VEGF, as it stimulates the formation of new blood vessels. In contrast, flavonoids derived from Phaleria macrocarpa extract possess inhibitory effects on both pro-inflammatory signaling molecules and pro-angiogenic pathways. This study investigated the effects of flavonoids from Phaleria macrocarpa extract on VEGF levels in the peritoneal fluid of endometriosis mouse models. This research employed a post-test-only control group experimental design. A total of thirty mice (Mus musculus) were assigned to six groups: a healthy control group, an untreated endometriosis group, and four endometriosis groups receiving isolated flavonoids from Phaleria macrocarpa extract at doses of 3.75, 7.5, 15, and 30 mg/mouse/day (n=5). Peritoneal fluid samples were collected from all groups to examine VEGF levels using ELISA. The results were expressed as mean ± SD and subsequently evaluated using a one-way ANOVA with LSD post-hoc test at a significance level of p-value < 0.05. Flavonoids at the dose of 30 mg/day significantly decreased the VEGF levels compared to the group of endometriosis mouse models (p-value=0.001). Flavonoids decreased VEGF levels as an angiogenic factor in peritoneal fluid, which may play a role in the proliferation of endometriosis tissue. Keywords: Flavonoid, Phaleria macrocarpa, VEGF, Endometriosis
Bladder Rhabdomyosarcoma in Adolescents at a Tertiary Centre in Indonesia: A Case Series with Focus on Age-Specific Treatment Response and Diagnostic Challenges Andhyka Brillian Kharisma; Ahmad Zulfan Hendri; Indrawarman Soeroharjo
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 3 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i3.25908

Abstract

Bladder rhabdomyosarcoma (RMS) is a rare type of soft tissue cancer in adolescents, and it often shows up with vague urinary symptoms that can be easy to miss. Compared to younger children, teenagers tend to respond less well to treatment and have lower survival rates, even when given equally intensive therapies. This difference seems to come from both biology and the challenges of diagnosis. We saw two adolescent male patients, aged 17 and 21, who came in with blood in the urine. Imaging with ultrasound and contrast CT scans revealed solid bladder masses with clear hyperenhancement (delta HU 37-38). Pathology and immunohistochemistry (desmin, myogenin, MyoD1) confirmed embryonal RMS, one conventional type and one botryoid variant. Both were staged as pT2bN0M0. Each patient underwent partial cystectomy after an initial TURBT. Neither received chemotherapy. Case 1 had a laparoscopic partial cystectomy in February 2023, while Case 2 had surgery three years earlier. Both were followed closely with cystoscopy every 3-6 months. At 30 and 36 months post-surgery, respectively, both remain disease-free, with normal bladder function and no need for catheters. These cases show that adolescents with localized bladder RMS can do well when the tumor is completely removed, even without chemotherapy. CT hyperenhancement helps raise suspicion, while immunohistochemistry confirms the diagnosis. Partial cystectomy not only achieves complete resection but also preserves bladder function. Ongoing surveillance is critical, and age-specific treatment strategies, focused on surgery plus careful follow-up, deserve further study for this group. Keywords: Rhabdomyosarcoma, Bladder Tumour, Adolescent, Age-Specific Treatment, Diagnostic Delay, Bladder Preservation, Partial Cystectom
Determinants of Relapse Among Schizophrenia Patients in West Kalimantan: A Cross-sectional Study Wahyu Kirana; Dewin Safitri; Yunita Dwi Anggreini
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 3 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i3.26541

Abstract

Relapse can affect functional impairment, rehospitalization, readmission, and long-term disability among schizophrenia patients. Although several factors, such as medication adherence, internalized stigma, and family support, are recognized as determining factors, there is still limited evidence from the Indonesian context, especially in West Kalimantan. This study aimed to evaluate the factors associated with relapse among schizophrenia patients. A quantitative, cross-sectional design was conducted at a mental hospital in West Kalimantan. A total of 63 patients and their families participated in this study, selected using a consecutive sampling technique. The MMAS-8, ISMI-9, and family support questionnaires were used to collect the data; patients completed the MMAS-8 and ISMI-9 questionnaires directly, whereas their&#8194;families completed the family support questionnaire using a Google Form. The patients' medical reports were used to identify the relapse rate. Data were analyzed using Fisher's exact test and multivariate logistic regression.? Fisher's exact test showed that medication adherence was significantly associated with relapse (p = 0.02, p < 0.05), while internalized stigma and family support were not associated (p = 0.21; p = 0.12, p > 0.05). Medication adherence was the strongest factor associated with relapse, with an Adjusted Odds Ratio (AOR) of 2.091. This finding suggests that schizophrenia patients with a low level of medication adherence were over two times more likely to experience a lifetime relapse compared to those with a higher level of medication adherence?Keywords: ?Family Support, Internalized Stigma, Medication Adherence, Relapse, Schizophrenia
Immunohistochemical Profile of Er, Pr, Her2, and Ki-67 In Breast Cancer Patients Marliana Nurprilinda; Erida Manalu; Tiroy Sari B. Simanjuntak; Reinhard Christovel Andreas
Contagion: Scientific Periodical Journal of Public Health and Coastal Health Vol 7, No 3 (2025): CONTAGION
Publisher : Universitas Islam Negeri Sumatera Utara, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/contagion.v7i3.25681

Abstract

Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide, with hormonal factors playing a critical role in tumor development and progression. This study aims to describe the immunohistochemical profile of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 in breast cancer patients at MRCCC Siloam Semanggi Hospital in 2022. A retrospective descriptive study was conducted using a total sampling of anatomical pathology archives, comprising 316 breast cancer cases. The most common age group was 40-49 years. ER positivity was observed in 229 patients (72.5%), while PR positivity was found in 183 patients (57.9%). HER2 overexpression (3+) was identified in 75 patients (23.7%); cases with equivocal HER2 (2+) required confirmation by in situ hybridization. High proliferative activity, indicated by Ki-67 ≥20%, was present in 262 patients (82.9%). These findings indicate a predominance of hormone receptor-positive tumors with high proliferative indices, highlighting the importance of immunohistochemical profiling in guiding prognosis assessment, therapeutic decision-making, and selection of targeted and systemic treatments in breast cancer management. Keywords: Breast Cancer, Immunohistochemistry, Estrogen Receptor (ER), HER2, Ki-67

Page 47 of 47 | Total Record : 465

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