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Sriwijaya Journal of Ophthalmology
Published by Universitas Sriwijaya
ISSN : -     EISSN : 27229807     DOI : https://doi.org/10.37275/sjo.v2i2.35
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology
Sriwijaya Journal of Opthalmology (SJO) is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Sriwijaya Journal of Opthalmology (SJO) publishes original article, case report and review article related opthalmology.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 91 Documents
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An Investigation of Keratoplasty Procedures and Their Outcomes in Iraq Leki, Rafid Hameed; Hind Essa Khairan; Meqdam Dawood Salman
Sriwijaya Journal of Ophthalmology Vol. 7 No. 1 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i1.118

Abstract

Introduction: The treatment of corneal disorders involves the use of various forms of keratoplasty. The objective of this study was to provide a detailed description of the various types of keratoplasty procedures performed in Iraq, as well as their corresponding outcomes. Methods: An observational study was conducted at Al-Zahraa Teaching Hospital to document cases of keratoplasty. The collected data included age, gender, types of keratoplasty, indications, previous surgical or medical history, and postoperative outcomes. The types of keratoplasty included penetrating keratoplasty (PKP), deep anterior lamellar keratoplasty (DALK), and Descemet's stripping endothelial keratoplasty (DSEK). Additionally, we performed cataract surgery and intraocular lens (IOL) insertion for those with cataracts, using either IOLs with scleral fixation or IOLs with iris fixation. We complete the task on the first day following the purchase order, then the first week, the first month, and every six months thereafter. Prior to surgery, patients with corneal vascularization had laser photocoagulation of the blood vessels in the cornea. Results: Ages range from 4 to 90. People over 40 (60.8%) were the most common age group. The female prevalence was 52.9%. Right-eye illness was diagnosed 51.6% of the time. 60% of patients underwent PKP. 26.8% had DALK, 12.4% had DSEK. Post keratoplasty, the statistically-significant improvement-ratio was 68.5% as eyes best corrected visual acuity (BCVA) improvement, while 12.2% of eyes showed a decline in BCVA and 19.3% discharged with no changes in BCVA. Postoperatively, BCVA was significantly lower in cases with a duration below 1 year (1.5), and better among the duration > 3 years (0.5). The greatest improvements were seen in cases with infective keratitis (-0.7), corneal dystrophies (-0.6), and advanced keratoconus (-0.7) whereas the lowest rates were documented in cases with a graft rejection (-0.3), and bullous keratopathy (-0.3) Conclusion: Keratoplasty is associated with a substantial enhancement of visual acuity in the younger population. Infective keratitis, keratoconus, and corneal dystrophy produce the most optimal and superior results. The PKP method is the most frequently performed.
Impact of COVID-19 on Preventable Blindness Detection in Bali, Indonesia Lestari, Ni Putu Dharmi; Gede Benny Setia Wirawan; I Putu Rustama Putra; Ni Wayan Sedani; Cynthia Dewi M
Sriwijaya Journal of Ophthalmology Vol. 7 No. 1 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i1.119

Abstract

Introduction: WHO, and the Indonesian government, have agreed to a plan to eradicate preventable blindness by 2020 in VISION 2020. However, the COVID-19 pandemic has caused a strain on the healthcare system. It is difficult to assess the impact of the pandemic on preventable blindness. Here we approach the issue by evaluating hospital visits for visual impairments in one regency in Bali, Indonesia. Methods: We collected outpatient visit records from three hospitals providing ophthalmologic clinics in Tabanan, Bali, Indonesia, a regency of 445 thousand people. We then conducted a descriptive analysis of the general changes in outpatient visits to these clinics and changes observed in different diagnoses identified as causes for preventable blindness. Results: The result showed a 35% downtrend in outpatient visits to the ophthalmologic clinic throughout the provinces. A more pronounced downtrend (45.22%) was observed for one public hospital that also serves as a COVID-19 referral hospital compared to private hospitals (around 30% each). By diagnoses, visits for cataracts were shown with a less severe downtrend compared to glaucoma, pterygium, and refractive disorders. Conclusion: Our study found a downtrend in outpatient visits for visual impairment in ophthalmologic clinics, which may be attributed to COVID-19 preventive measures by the hospital as well as patient reluctance due to fear of COVID-19 transmission. Public health communication needs to address this fear to recover patient confidence while maintaining vigilance in practicing COVID-19 preventive behavior.
Risk Factors and Management Strategies for Dry Eye Syndrome: A Comparative Study Ehsan Khalil Abed; Abbood, Aiad Ali
Sriwijaya Journal of Ophthalmology Vol. 7 No. 2 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i2.120

Abstract

Introduction: Dry eye syndrome (DES) is a prevalent multifactorial ocular surface disorder characterized by discomfort, visual disturbances, and tear film instability. This study aimed to investigate the risk factors associated with DES and compare the effectiveness of various management strategies. Methods: A cross-sectional comparative study was conducted at an ophthalmic consultant clinic from March 2023 to October 2023. One hundred patients diagnosed with DES were enrolled. Demographic data, including age, gender, and body mass index (BMI), were collected. Ophthalmological examinations, including slit-lamp examination, non-contact tonometry, fundus examination, tear break-up time (TBUT) measurement, and ocular surface disease index (OSDI) questionnaire assessment, were performed. The management strategies employed were categorized as medical, surgical, or a combination of both. Results: The study population predominantly consisted of females (70%) with a mean age of 49.65 years. The majority of patients (57%) fell within the overweight BMI category (25-29 kg/m2). TBUT values of 7 seconds and 8 seconds were most prevalent (35% and 37%, respectively), and the majority of patients (65%) reported an OSDI score of 2. Notably, two-thirds of patients received medical treatment, one-third underwent a combination of medical and surgical treatment, and a small proportion (5%) underwent surgery alone. Conclusion: Female gender, increased BMI, and older age were identified as significant risk factors for DES. Patients with DES symptoms exhibited shorter TBUT values and higher OSDI scores, indicating tear film instability and increased disease severity. Medical treatment was the most common management strategy, followed by a combination of medical and surgical interventions. These findings underscore the importance of early diagnosis and individualized treatment plans for effective DES management.
Computer Vision Syndrome in High School Students: The Role of Gadget Use Intensity Gufraan, Ghathan; Said Munazar Rahmat
Sriwijaya Journal of Ophthalmology Vol. 7 No. 2 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i2.121

Abstract

Introduction: The ubiquity of digital devices in the lives of high school students has raised concerns about the potential impact on their visual health. Computer vision syndrome (CVS), a constellation of eye and vision-related problems, has been linked to prolonged digital screen use. This study aimed to investigate the relationship between gadget use intensity and the prevalence and severity of CVS in high school students. Methods: A cross-sectional study was conducted involving a sample of high school students. Data on gadget use intensity (hours per day) and CVS symptoms were collected through validated questionnaires. The Computer Vision Symptom Scale (CVSS) was used to assess the severity of CVS. Statistical analyses were performed to examine the association between gadget use intensity and CVS prevalence and severity. Results: The study found a significant positive correlation between gadget use intensity and the prevalence and severity of CVS in high school students. Students who reported higher levels of gadget use were more likely to experience CVS symptoms and exhibit greater symptom severity. Conclusion: The findings underscore the importance of promoting healthy gadget use habits among high school students. Interventions aimed at reducing screen time and encouraging regular breaks may be crucial in mitigating the risk of CVS and its associated visual discomfort.
Refractive Error Correction in Bali, Indonesia: A Retrospective Cohort Study of ReLEx SMILE and Femto-LASIK Outcomes Semara Budiyasa; Indira Putri
Sriwijaya Journal of Ophthalmology Vol. 7 No. 2 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i2.122

Abstract

Introduction: Technological advances have driven progress in surgical techniques for refractive problems, including the use of laser-assisted in situ keratomileusis (LASIK) through the ReLEx SMILE and Femto-LASIK methods. While Bali Mandara Eye Hospital pioneered LASIK procedures in Bali Province, there has been no research to date evaluating the outcomes of these procedures. Methods: This retrospective cohort study analyzed medical record data from patients with refractive disorders who underwent LASIK surgery at Bali Mandara Eye Hospital between January and December 2023. The data collected included patient demographics, pre-and post-operative visual acuity, and the type of LASIK surgery performed. Results: The study included 151 eyes. The majority of patients were male (52.3%), aged 17-29 years, had a college education (60.3%), worked in the private sector (38%), resided in Bali (86%), and underwent the ReLEx SMILE procedure (60.3%). Both Femto-LASIK and ReLEx SMILE procedures yielded excellent visual outcomes and were considered safe. Post-operative uncorrected visual acuity (UCVA) improved to the level of pre-operative best-corrected visual acuity (BCVA) in 137 eyes (90.73%). Conclusion: The ReLEx SMILE and Femto-LASIK methods are both safe and effective procedures for correcting refractive errors, particularly mild myopia. There was no significant difference in visual outcomes between the two methods.
Shifting Patterns of Ocular Emergencies: A Comparative Study in Basrah, Iraq Mokhles Jerri Meften Al-Sabti; Khalid Tawfeeq Najm Alsayab
Sriwijaya Journal of Ophthalmology Vol. 7 No. 2 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i2.123

Abstract

Introduction: Ocular emergencies present a significant public health concern, potentially leading to vision loss if not addressed promptly. Understanding the dynamics of these emergencies is essential for effective healthcare planning and resource allocation. This study aimed to analyze the trends and characteristics of ocular emergencies in Basrah, Iraq, and compare them with historical data. Methods: A retrospective study was conducted at Al-Sayab Teaching Hospital in Basrah, involving 250 patients presenting to the ophthalmology emergency department between January 1st, 2023, and December 31st, 2023. Data regarding demographics, presentation time, causes of emergencies, and visual acuity were analyzed. Results: The leading causes of ocular emergencies were inflammatory diseases (32%), trauma (28%), and foreign bodies (33.2%). A significant proportion of patients (20%) presented with severe visual impairment (less than 20/200). Most emergencies occurred in males (72.4%), primarily in the 20-40 year age group. Conclusion: The study highlights a high prevalence of inflammatory diseases and trauma among ocular emergencies in Basrah. Public health interventions should focus on preventing ocular trauma and improving access to eye care services. Continuous monitoring of these patterns is crucial for effective public health planning.
Predicting Glaucoma Progression with Artificial Intelligence: A Meta-Analysis of Machine Learning Models Indira Putri
Sriwijaya Journal of Ophthalmology Vol. 7 No. 2 (2024): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v7i2.124

Abstract

Introduction: Glaucoma, a leading cause of irreversible blindness, requires early detection and prediction of progression to preserve vision. Artificial intelligence (AI) offers promising tools for analyzing complex ophthalmic data and identifying high-risk individuals. This meta-analysis evaluates the performance of machine learning (ML) models in predicting glaucoma progression. Methods: A systematic search of PubMed, Scopus, and Web of Science databases was conducted for studies published between 2013 and 2024 that investigated the use of ML models to predict glaucoma progression. Studies reporting performance metrics like sensitivity, specificity, area under the receiver operating characteristic curve (AUC), and accuracy were included. Results: Six studies met the inclusion criteria, encompassing 1,250 participants. The pooled sensitivity and specificity of ML models for predicting glaucoma progression were 0.81 (95% CI: 0.78-0.84) and 0.77 (95% CI: 0.73-0.81), respectively. The pooled AUC was 0.88 (95% CI: 0.86-0.90), indicating excellent discriminatory ability. Conclusion: ML models hold significant potential for predicting glaucoma progression with high accuracy. Further research with larger, more diverse datasets is needed to validate these findings and develop clinically applicable tools.
Eyelid Squamous Cell Carcinoma in Palembang, Indonesia: A 5-Year Retrospective Study Zahratul Riadho; Adinda Dwivana Malika; Wardiansah
Sriwijaya Journal of Ophthalmology Vol. 8 No. 1 (2025): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v8i1.128

Abstract

Introduction: Eyelid squamous cell carcinoma (SCC) is a prevalent malignancy with potentially severe consequences if not detected and managed early. This study aimed to investigate the prevalence, clinical characteristics, and histopathological features of eyelid SCC patients at Dr. Mohammad Hoesin General Hospital Palembang, Indonesia, over a 5-year period. Methods: A retrospective analysis of medical records was conducted on 20 patients diagnosed with eyelid SCC between 2020 and 2024. Data on demographics, clinical presentation, tumor characteristics, and histopathological findings were collected and analyzed. Univariate analysis was performed to describe the characteristics of the study population. Correlation tests were conducted to explore the relationships between various factors and eyelid SCC. Results: The prevalence of eyelid SCC was 16.67%, with the highest incidence in 2024 (25%). The majority of patients were ≥ 50 years old (60%), with an equal distribution between males and females. Outdoor occupations (45%) and lower education levels (60% with primary education) were common characteristics. Lesions were mostly multiple (45%), >3cm in size (55%), and located on the right side (60%). Histopathological analysis revealed well-differentiated (25%) and poorly differentiated (25%) SCC as the most common subtypes. Correlation analysis revealed significant associations between age and tumor size, occupation and tumor size, education level and tumor size, smoking status and differentiation, tumor size and lymphovascular invasion, and perineural invasion and differentiation. Conclusion: Eyelid SCC in Palembang predominantly affects older individuals with outdoor occupations and lower education levels. Multiple, large, and right-sided lesions are frequent findings. Emphasis on sun protection and early detection is crucial, particularly for outdoor workers.
Neutrophil-to-Lymphocyte Ratio as a Predictive Biomarker for Retinopathy of Prematurity: A Systematic Review Ayu Diah Permatasari; I Wayan Eka Sutyawan; Ni Made Ayu Surasmiati
Sriwijaya Journal of Ophthalmology Vol. 8 No. 1 (2025): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v8i1.130

Abstract

Introduction: Retinopathy of prematurity (ROP) remains a leading cause of childhood blindness, with its pathogenesis linked to aberrant vascular development and systemic inflammation. There is a critical need for accessible biomarkers to improve risk stratification beyond current screening standards. This systematic review critically appraises the evidence for the neutrophil-to-lymphocyte ratio (NLR), a widely available inflammatory marker, as a predictor of ROP. Methods: Following PRISMA 2020 guidelines, a systematic search was conducted in PubMed, ScienceDirect, ProQuest, and SpringerLink for observational studies published between January 1st, 2015, and December 31st, 2024. Studies assessing the association between NLR and ROP in preterm infants were included. Two reviewers independently performed study selection, data extraction, and a formal risk-of-bias assessment using the Newcastle-Ottawa Scale (NOS). A narrative synthesis was performed due to significant heterogeneity. Results: The search identified 32 records, with 6 retrospective studies ultimately meeting the inclusion criteria, encompassing a total reported sample of 1,065 infants. The methodological quality of the included studies was low to moderate, with NOS scores ranging from 5 to 7 out of a possible 9. The evidence base was defined by profound methodological heterogeneity, particularly in the timing of blood sample collection, which was unspecified in half of the studies, and inconsistent reporting of core population data. A narrative synthesis of the findings showed that several studies reported a statistical association between an elevated NLR or related inflammatory markers and ROP. However, one study reported no significant association, and the interpretation of others was complicated by a focus on different biomarkers or a lack of statistical significance. Conclusion: The available evidence, derived exclusively from retrospective studies of varying quality, suggests a possible association between elevated NLR and ROP, a link supported by strong biological plausibility. However, the current evidence base is severely limited by methodological flaws and profound heterogeneity, making it insufficient to support the adoption of NLR into clinical practice. NLR is not a standalone diagnostic or predictive tool for ROP. Its potential utility can only be realized through large-scale, methodologically rigorous prospective studies designed to overcome the limitations identified in this review.
Navigating Therapeutic Challenges in Adult-Onset Coats' Disease: Successful Vitrectomy for Tractional Retinal Detachment Following Laser Photocoagulation Albatool Alqahtani; Faisal Al-Qahtani; Abdullah Al Hilali; Alwaleed Alsulaiman
Sriwijaya Journal of Ophthalmology Vol. 8 No. 1 (2025): Sriwijaya Journal of Ophthalmology
Publisher : Department of Opthalmology, Faculty of Medicine, Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjo.v8i1.131

Abstract

Introduction: Adult-onset Coats' disease, an infrequent variant of idiopathic exudative retinopathy, presents a unique management paradigm. While laser photocoagulation is a primary treatment for the characteristic retinal telangiectasia, it can paradoxically trigger a severe inflammatory and fibrotic cascade, leading to vision-threatening complications. This report addresses a critical clinical question: What is the optimal management strategy when first-line ablative therapy not only fails but leads to iatrogenic tractional retinal detachment? Case presentation: A 35-year-old male presented with a 15-day history of metamorphopsia in his right eye. Best-corrected visual acuity (BCVA) was 20/20. Multimodal imaging confirmed Stage 2B Coats' disease. Following sectoral argon laser photocoagulation, his BCVA declined to a nadir of 20/60. Within two months of laser, optical coherence tomography (OCT) documented the rapid development of an epiretinal membrane and a subsequent superior macular tractional retinal detachment (TRD). A 23-gauge pars plana vitrectomy (PPV) with membrane peeling was performed. Anatomical success was achieved, and at the six-month follow-up, the retina remained attached, and BCVA improved to 20/40. Conclusion: This case demonstrates that laser-induced inflammation can rapidly convert an exudative process into a complex fibro-proliferative state in adult-onset Coats' disease. When confronted with iatrogenic fibrosis, medical management is insufficient. This report validates that timely and definitive surgical intervention with PPV is not merely an option but an essential strategy for reversing the disease trajectory, achieving anatomical restoration, and salvaging vision.

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